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Drug Development and Industrial Pharmacy Volume 25, 1999 - Issue 1
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Research Article

In Vitro Release Kinetics of Gentamycin from a Sodium Hyaluronate Gel Delivery System Suitable for the Treatment of Peripheral Vestibular Disease

R. Michael Kelly Center for Pharmaceutical Biotechnology and Department of Pharmaceutical Sciences, School of Pharmacy, University of Colorado Health Sciences Center, Denver, CO, 80262, U.S.A.
,
Jeffrey D. Meyer Center for Pharmaceutical Biotechnology and Department of Pharmaceutical Sciences, School of Pharmacy, University of Colorado Health Sciences Center, Denver, CO, 80262, U.S.A.
,
James E. Matsuura Center for Pharmaceutical Biotechnology and Department of Pharmaceutical Sciences, School of Pharmacy, University of Colorado Health Sciences Center, Denver, CO, 80262, U.S.A.
,
Eli Shefter
,
Michael J. Hart Iowa Ear Clinic, 1000 73rd St., West Des Moines, IA, 50265, U.S.A.
,
Daniel J. Malone Department of Pharmacy Practice, School of Pharmacy, University of Colorado Health Sciences Center, Denver, CO, 80262, U.S.A.
&
Mark C. Manning Center for Pharmaceutical Biotechnology and Department of Pharmaceutical Sciences, School of Pharmacy, University of Colorado Health Sciences Center, Denver, CO, 80262, U.S.A.
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Pages 15-20 | Published online: 14 Jan 1999

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Guo Shan-Bin, Tian Yue & Jian Ling-Yan. (2015) Long-term sustained-released in situ gels of a water-insoluble drug amphotericin B for mycotic arthritis intra-articular administration: preparation, in vitro and in vivo evaluation. Drug Development and Industrial Pharmacy 41:4, pages 573-582.
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Hongzhuo Liu, Liang Feng, Gaurav Tolia, Mark R. Liddell, Jinsong Hao & S. Kevin Li. (2014) Evaluation of intratympanic formulations for inner ear delivery: methodology and sustained release formulation testing. Drug Development and Industrial Pharmacy 40:7, pages 896-903.
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Articles from other publishers (19)

Kwadwo Mfoafo, Rahul Mittal, Adrien Eshraghi, Yadollah Omidi & Hossein Omidian. (2023) Improved inner ear drug delivery using hydrogel carriers. Journal of Drug Delivery Science and Technology 79, pages 104086.
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Fabrice Piu & Kathie M. Bishop. (2019) Local Drug Delivery for the Treatment of Neurotology Disorders. Frontiers in Cellular Neuroscience 13.
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Batoryna Olgierd, Aleksandra Sklarek, Paulina Siwek & Ewa Waluga. 2019. Stem Cells and Biomaterials for Regenerative Medicine. Stem Cells and Biomaterials for Regenerative Medicine 163 189 .
Che Xin, Wang Lihong, Li Qiuyuan & Liu Hongzhuo. (2014) Injectable long-term control-released in situ gels of hydrochloric thiothixene for the treatment of schizophrenia: Preparation, in vitro and in vivo evaluation. International Journal of Pharmaceutics 469:1, pages 23-30.
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Clemens Honeder, Elisabeth Engleder, Hanna Schöpper, Franz Gabor, Gottfried Reznicek, Jens Wagenblast, Wolfgang Gstoettner & Christoph Arnoldner. (2014) Sustained Release of Triamcinolone Acetonide from an Intratympanically Applied Hydrogel Designed for the Delivery of High Glucocorticoid Doses. Audiology and Neurotology 19:3, pages 193-202.
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Yanina Minaberry, Diego A. ChiappettaAlejandro SosnikMatías Jobbágy. (2012) Micro/Nanostructured Hyaluronic Acid Matrices with Tuned Swelling and Drug Release Properties. Biomacromolecules 14:1, pages 1-9.
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JIARONG CHEN, LIU YANG, LIN GUO & XIAOJUN DUAN. (2012) Sodium hyaluronate as a drug-release system for VEGF 165 improves graft revascularization in anterior cruciate ligament reconstruction in a rabbit model. Experimental and Therapeutic Medicine 4:3, pages 430-434.
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Seiji B. ShibataSarah R. CortezJames A. WilerDonald L. SwiderskiYehoash Raphael. (2012) Hyaluronic Acid Enhances Gene Delivery into the Cochlea. Human Gene Therapy 23:3, pages 302-310.
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Xiaobo Wang, Luis Dellamary, Rayne Fernandez, Qiang Ye, Carl LeBel & Fabrice Piu. (2011) Principles of inner ear sustained release following intratympanic administration. The Laryngoscope 121:2, pages 385-391.
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Davide Campoccia, Lucio Montanaro, Pietro Speziale & Carla Renata Arciola. (2010) Antibiotic-loaded biomaterials and the risks for the spread of antibiotic resistance following their prophylactic and therapeutic clinical use. Biomaterials 31:25, pages 6363-6377.
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Amanj Saber, Göran Laurell, Tobias Bramer, Katarina Edsman, Cecilia Engmér & Mats Ulfendahl. (2009) Middle Ear Application of a Sodium Hyaluronate Gel Loaded with Neomycin in a Guinea Pig Model. Ear & Hearing 30:1, pages 81-89.
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Martin S. Spitzer, Efdal Yoeruek, Radoslaw T. Kaczmarek, Ana Sierra, Sabine Aisenbrey, Salvatore Grisanti, Karl U. Bartz-Schmidt & Peter Szurman. (2008) Sodium hyaluronate gels as a drug-release system for corticosteroids: release kinetics and antiproliferative potential for glaucoma surgery. Acta Ophthalmologica 86:8, pages 842-848.
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John K.M. Coleman, Cherllynn Littlesunday, Ronald Jackson & Thomas Meyer. (2007) AM-111 protects against permanent hearing loss from impulse noise trauma. Hearing Research 226:1-2, pages 70-78.
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Mar Fernandez, Juan Parra, Blanca Vazquez, Antonio Lopez-Bravo & Julio San Román. (2005) Self-curing controlled release systems for steroids. Application of prednisolone-based polymeric systems to ear diseases. Biomaterials 26:16, pages 3311-3318.
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William M. Sheppard, Hayes H. Wanamaker, Adam Pack, Satoshi Yamamoto & Norma Slepecky. (2016) Direct Round Window Application of Gentamicin with Varying Delivery Vehicles: A Comparison of Ototoxicity. Otolaryngology–Head and Neck Surgery 131:6, pages 890-896.
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Hayes H. Wanamaker. (2001) Perfusion of the inner ear: basic science considerations. Current Opinion in Otolaryngology & Head and Neck Surgery 9:5, pages 329-332.
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Tamaki Miyazaki, Chikako Yomota & Satoshi Okada. (2001) Development and release characterization of hyaluronan?doxycycline gels based on metal coordination. Journal of Controlled Release 76:3, pages 337-347.
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Yi Luo, Kelly R Kirker & Glenn D Prestwich. (2000) Cross-linked hyaluronic acid hydrogel films: new biomaterials for drug delivery. Journal of Controlled Release 69:1, pages 169-184.
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Paul F. Smith. (2000) Pharmacology of the vestibular system. Current Opinion in Neurology 13:1, pages 31-37.
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