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Research Article

Investigation of Prandial Effects on Hydrophilic Matrix Tablets

Pages 765-771 | Published online: 18 May 1999

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Read on this site (3)

Ali Nokhodchi & Kofi Asare-Addo. (2014) Drug release from matrix tablets: physiological parameters and the effect of food. Expert Opinion on Drug Delivery 11:9, pages 1401-1418.
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Joseph Kukura, Paulo E. Arratia, Edit S. Szalai & Fernando J. Muzzio. (2003) Engineering Tools for Understanding the Hydrodynamics of Dissolution Tests. Drug Development and Industrial Pharmacy 29:2, pages 231-239.
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Xiaohong Mu, Michael J. Tobyn & John N. Staniforth. (2003) Influence of Physiological Variables on the In Vitro Drug-Release Behavior of a Polysaccharide Matrix Controlled-Release System. Drug Development and Industrial Pharmacy 29:1, pages 19-29.
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Articles from other publishers (38)

Zherui Zhang, Shumin Chen, Man Wen, Haibing He, Yu Zhang, Tian Yin, Jingxin Gou & Xing Tang. (2022) Alleviating the Influence of Circadian Rhythms and Drug Properties to the Release of Paliperidone Gel Matrix Tablets with Compression Coating Technology and Microenvironment Shaping. AAPS PharmSciTech 23:7.
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Matthew D. Burke & Michael C. Koetting. (2020) Development of a Clinically Relevant Dissolution Approach to Simulate Physiological Forces with a USP 2 Apparatus: “Peristaltic Dissolution”. Journal of Pharmaceutical Innovation 16:4, pages 699-714.
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Seyedreza Goldoozian, Valentyn Mohylyuk, Andriy Dashevskiy & Roland Bodmeier. (2021) Gel Strength of Hydrophilic Matrix Tablets in Terms of In Vitro Robustness. Pharmaceutical Research.
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Helena Vrbanac, Jurij Trontelj, Sandra Berglez, Klemen Kreft, Dejan Krajcar & Igor Legen. (2020) Simulated migrating motor complex and its impact on the release properties of hydrophilic matrix systems. Journal of Drug Delivery Science and Technology 55, pages 101338.
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Helena Vrbanac & Ana Krese. (2019) The influence of different mechanical stress on the release properties of HPMC matrix tablets in sucrose-NaCl media. Journal of Drug Delivery Science and Technology 54, pages 101246.
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Matthew Hopgood, Gavin Reynolds & Richard Barker. (2018) Using Computational Fluid Dynamics to Compare Shear Rate and Turbulence in the TIM-Automated Gastric Compartment With USP Apparatus II. Journal of Pharmaceutical Sciences 107:7, pages 1911-1919.
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R. Ali, A. Dashevsky & R. Bodmeier. (2017) Poly vinyl acetate and ammonio methacrylate copolymer as unconventional polymer blends increase the mechanical robustness of HPMC matrix tablets. International Journal of Pharmaceutics 516:1-2, pages 3-8.
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Jens Van Den Abeele, Jari Rubbens, Joachim Brouwers & Patrick Augustijns. (2017) The dynamic gastric environment and its impact on drug and formulation behaviour. European Journal of Pharmaceutical Sciences 96, pages 207-231.
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Bart Hens, Maura Corsetti, Joachim Brouwers & Patrick Augustijns. (2016) Gastrointestinal and Systemic Monitoring of Posaconazole in Humans After Fasted and Fed State Administration of a Solid Dispersion. Journal of Pharmaceutical Sciences 105:9, pages 2904-2912.
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Laura M. Mason, Simona Chessa, Hiep Huatan, David E. Storey, Pranav Gupta, Jonathan Burley & Colin D. Melia. (2016) Use of the Dynamic Gastric Model as a tool for investigating fed and fasted sensitivities of low polymer content hydrophilic matrix formulations. International Journal of Pharmaceutics 510:1, pages 210-220.
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Kofi Asare-Addo, Enes Supuk, Mohammed H. Mahdi, Adeola O. Adebisi, Elijah Nep, Barbara R. Conway, Waseem Kaialy, Hiba Al-Hamidi & Ali Nokhodchi. (2016) Drug release from E chemistry hypromellose tablets using the Bio-Dis USP type III apparatus: An evaluation of the effect of systematic agitation and ionic strength. Colloids and Surfaces B: Biointerfaces 143, pages 481-489.
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Marija Ilić, Ivan Kovačević & Jelena Parojčić. (2015) Deciphering nifedipine in vivo delivery from modified release dosage forms: Identification of food effect. Acta Pharmaceutica 65:4.
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Raxit Y. Mehta, Shahrzad Missaghi, Sandip B. Tiwari & Ali R. Rajabi-Siahboomi. (2014) Application of Ethylcellulose Coating to Hydrophilic Matrices: A Strategy to Modulate Drug Release Profile and Reduce Drug Release Variability. AAPS PharmSciTech 15:5, pages 1049-1059.
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Patrik Knöös, Marie Wahlgren, Daniel Topgaard, Stefan Ulvenlund & Lennart Piculell. (2014) Effects of Added Surfactant on Swelling and Molecular Transport in Drug-Loaded Tablets Based on Hydrophobically Modified Poly(acrylic acid). The Journal of Physical Chemistry B 118:32, pages 9757-9767.
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Patrik Knöös, Christopher Schulz, Lennart Piculell, Roland Ludwig, Lo Gorton & Marie Wahlgren. (2014) Quantifying the release of lactose from polymer matrix tablets with an amperometric biosensor utilizing cellobiose dehydrogenase. International Journal of Pharmaceutics 468:1-2, pages 121-132.
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Mirko Koziolek, Kristin Görke, Marco Neumann, Grzegorz Garbacz & Werner Weitschies. (2014) Development of a bio-relevant dissolution test device simulating mechanical aspects present in the fed stomach. European Journal of Pharmaceutical Sciences 57, pages 250-256.
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Fiona MacDougall, Lee Ann Hodges & Howard N. E. Stevens. 2014. Hydrophilic Matrix Tablets for Oral Controlled Release. Hydrophilic Matrix Tablets for Oral Controlled Release 281 321 .
Mirko Koziolek, Grzegorz Garbacz, Marco Neumann & Werner Weitschies. (2013) Simulating the Postprandial Stomach: Biorelevant Test Methods for the Estimation of Intragastric Drug Dissolution. Molecular Pharmaceutics 10:6, pages 2211-2221.
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Kofi Asare-Addo, Waseem Kaialy, Marina Levina, Ali Rajabi-Siahboomi, Mohammed U. Ghori, Enes Supuk, Peter R. Laity, Barbara R. Conway & Ali Nokhodchi. (2013) The influence of agitation sequence and ionic strength on in vitro drug release from hypromellose (E4M and K4M) ER matrices—The use of the USP III apparatus. Colloids and Surfaces B: Biointerfaces 104, pages 54-60.
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Kofi Asare-Addo, Marina Levina, Ali R. Rajabi-Siahboomi & Ali Nokhodchi. (2011) Effect of ionic strength and pH of dissolution media on theophylline release from hypromellose matrix tablets—Apparatus USP III, simulated fasted and fed conditions. Carbohydrate Polymers 86:1, pages 85-93.
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L. Ochoa, M. Igartua, R.M. Hernández, A.R. Gascón, M.A. Solinis & J.L. Pedraz. (2011) Novel extended-release formulation of lovastatin by one-step melt granulation: In vitro and in vivo evaluation. European Journal of Pharmaceutics and Biopharmaceutics 77:2, pages 306-312.
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Kofi Asare-Addo, Marina Levina, Ali R. Rajabi-Siahboomi & Ali Nokhodchi. (2010) Study of dissolution hydrodynamic conditions versus drug release from hypromellose matrices: The influence of agitation sequence. Colloids and Surfaces B: Biointerfaces 81:2, pages 452-460.
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Hywel D. Williams, David A. Barrett, Robert Ward, Ian J. Hardy & Colin D. Melia. (2010) A liquid chromatography method for quantifying caffeine dissolution from pharmaceutical formulations into colloidal, fat-rich media. Journal of Chromatography B 878:21, pages 1739-1745.
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Alistair C Ross, Ross J Macrae, Mathias Walther & Howard N E Stevens. (2000) Chronopharmaceutical Drug Delivery from a Pulsatile Capsule Device based on Programmable Erosion. Journal of Pharmacy and Pharmacology 52:8, pages 903-909.
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N. Fotaki, A. Aivaliotis, J. Butler, J. Dressman, M. Fischbach, J. Hempenstall, S. Klein & C. Reppas. (2009) A comparative study of different release apparatus in generating in vitro–in vivo correlations for extended release formulations. European Journal of Pharmaceutics and Biopharmaceutics 73:1, pages 115-120.
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Deirdre M. D’Arcy, Anne Marie Healy & Owen I. Corrigan. (2009) Towards determining appropriate hydrodynamic conditions for in vitro in vivo correlations using computational fluid dynamics. European Journal of Pharmaceutical Sciences 37:3-4, pages 291-299.
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Farhad Tajarobi, Susanna Abrahmsén-Alami, Magnus Hansen & Anette Larsson. (2009) The Impact of Dose and Solubility of Additives on the Release from HPMC Matrix Tablets—Identifying Critical Conditions. Pharmaceutical Research 26:6, pages 1496-1503.
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A. Diakidou, M. Vertzoni, B. Abrahamsson, J. Dressman & C. Reppas. (2009) Simulation of gastric lipolysis and prediction of felodipine release from a matrix tablet in the fed stomach. European Journal of Pharmaceutical Sciences 37:2, pages 133-140.
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Grzegorz Garbacz, Ralph-Steven Wedemeyer, Stefan Nagel, Thomas Giessmann, Hubert Mönnikes, Clive G. Wilson, Werner Siegmund & Werner Weitschies. (2008) Irregular absorption profiles observed from diclofenac extended release tablets can be predicted using a dissolution test apparatus that mimics in vivo physical stresses. European Journal of Pharmaceutics and Biopharmaceutics 70:2, pages 421-428.
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Eddy Castellanos Gil, Antonio Iraizoz Colarte, José Lizardo Lara Sampedro & Bernard Bataille. (2008) Subcoating with Kollidon VA 64 as water barrier in a new combined native dextran/HPMC–cetyl alcohol controlled release tablet. European Journal of Pharmaceutics and Biopharmaceutics 69:1, pages 303-311.
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Eddy Castellanos Gil, Antonio Iraizoz Colarte, Abdelsam El Ghzaoui, Denis Durand, Jean Louis Delarbre & Bernard Bataille. (2008) A sugar cane native dextran as an innovative functional excipient for the development of pharmaceutical tablets. European Journal of Pharmaceutics and Biopharmaceutics 68:2, pages 319-329.
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H. Lennernäs, B. Abrahamsson, E.M. Persson & L. Knutson. (2007) Oral drug absorption and the Biopharmaceutics Classification System. Journal of Drug Delivery Science and Technology 17:4, pages 237-244.
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Werner Weitschies, Ralph-Steven Wedemeyer, Olaf Kosch, Kilian Fach, Stefan Nagel, Erik Söderlind, Lutz Trahms, Bertil Abrahamsson & Hubert Mönnikes. (2005) Impact of the intragastric location of extended release tablets on food interactions. Journal of Controlled Release 108:2-3, pages 375-385.
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Bertil Abrahamsson, Anupam Pal, Marie Sjöberg, Maria Carlsson, Emma Laurell & James G. Brasseur. (2005) A Novel in Vitro and Numerical Analysis of Shear-Induced Drug Release from Extended-Release Tablets in the Fed Stomach. Pharmaceutical Research 22:8, pages 1215-1226.
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Shrutidevi Agrawal & Ramesh Panchagnula. (2004) Dissolution test as a surrogate for quality evaluation of rifampicin containing fixed dose combination formulations. International Journal of Pharmaceutics 287:1-2, pages 97-112.
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Nicole Kavanagh & Owen I Corrigan. (2004) Swelling and erosion properties of hydroxypropylmethylcellulose (Hypromellose) matrices—influence of agitation rate and dissolution medium composition. International Journal of Pharmaceutics 279:1-2, pages 141-152.
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Bertil Abrahamsson, Tamsin Albery, Anna Eriksson, Ingrid Gustafsson & Marie Sjöberg. (2004) Food effects on tablet disintegration. European Journal of Pharmaceutical Sciences 22:2-3, pages 165-172.
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Xiaohong Mu, Michael J Tobyn & John N Staniforth. (2003) Development and evaluation of bio-dissolution systems capable of detecting the food effect on a polysaccharide-based matrix system. Journal of Controlled Release 93:3, pages 309-318.
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