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Drug Development and Industrial Pharmacy Volume 28, 2002 - Issue 6
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Research Article

Hydrodynamic Flows Around Tablets in Different Pharmacopeial Dissolution Tests

M. Morihara National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-Ku, Tokyo, 158-8501, Japan
,
N. Aoyagi National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-Ku, Tokyo, 158-8501, Japan
,
N. Kaniwa National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-Ku, Tokyo, 158-8501, Japan
,
N. Katori National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-Ku, Tokyo, 158-8501, Japan
&
S. Kojim National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-Ku, Tokyo, 158-8501, Japan
Pages 655-662 | Published online: 17 Jun 2002

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Yan Wu, D. O. Kildsig & E. S. Ghaly. (2004) Effect of Hydrodynamic Environment on Tablets Dissolution Rate. Pharmaceutical Development and Technology 9:1, pages 25-37.
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Articles from other publishers (24)

Shotaro Ikuta, Hidetoshi Nakagawa, Toshiya Kai & Kiyohiko Sugano. (2024) Bicarbonate buffer dissolution test with gentle mechanistic stress for bioequivalence prediction of enteric-coated pellet formulations. European Journal of Pharmaceutical Sciences 192, pages 106622.
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Shotaro Ikuta, Hidetoshi Nakagawa, Toshiya Kai & Kiyohiko Sugano. (2023) Development of bicarbonate buffer flow-through cell dissolution test and its application in prediction of in vivo performance of colon targeting tablets. European Journal of Pharmaceutical Sciences 180, pages 106326.
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Freja Fredholt, Camilla Di Meo, Stine Sloth, Anette Müllertz & Ragna Berthelsen. (2022) Direct visualizing of paracetamol immediate release tablet disintegration in vivo and in vitro. European Journal of Pharmaceutics and Biopharmaceutics 180, pages 63-70.
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Hiroyuki Yoshida, Keita Teruya, Yasuhiro Abe, Takayuki Furuishi, Kaori Fukuzawa, Etsuo Yonemochi & Ken-ichi Izutsu. (2021) Altered Media Flow and Tablet Position as Factors of How Air Bubbles Affect Dissolution of Disintegrating and Non-disintegrating Tablets Using a USP 4 Flow-Through Cell Apparatus. AAPS PharmSciTech 22:7.
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Kaushalendra Chaturvedi, Harsh S. Shah, Rusha Sardhara, Kajal Nahar, Rutesh H. Dave & Kenneth R. Morris. (2021) Protocol development, validation, and troubleshooting of in-situ fiber optic bathless dissolution system (FODS) for a pharmaceutical drug testing. Journal of Pharmaceutical and Biomedical Analysis 195, pages 113833.
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Hiroyuki Yoshida, Yasuhiro Abe, Naomi Tomita & Ken-ichi Izutsu. (2020) Utilization of Diluted Compendial Media as Dissolution Test Solutions with Low Buffer Capacity for the Investigation of Dissolution Rate of Highly Soluble Immediate Release Drug Products. Chemical and Pharmaceutical Bulletin 68:7, pages 664-670.
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Andres F. Martinez, Kushal Sinha, Nandkishor Nere, Russell Slade & Steven Castleberry. (2020) Characterization of the Hydrodynamics in the USP Basket Apparatus Using Computational Fluid Dynamics. Journal of Pharmaceutical Sciences 109:3, pages 1231-1241.
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Vaibhav Rastogi, Pragya Yadav, Niharika Lal, Pallavi Rastogi, B.K. Singh, Navneet Verma & Anurag Verma. (2018) Mathematical prediction of pharmacokinetic parameters-an in-vitro approach for investigating pharmaceutical products for IVIVC. Future Journal of Pharmaceutical Sciences 4:2, pages 175-184.
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Yoshiko Takeuchi, Rina Usui, Hidekazu Ikezaki, Kohei Tahara & Hirofumi Takeuchi. (2017) Characterization of orally disintegrating films: A feasibility study using an electronic taste sensor and a flow-through cell. Journal of Drug Delivery Science and Technology 39, pages 104-112.
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Lijie Wang, Kai Chen, Haoyang Wen, Defang Ouyang, Xue Li, Yunyun Gao, Weisan Pan & Xinggang Yang. (2016) Design and Evaluation of Hydrophilic Matrix System Containing Polyethylene Oxides for the Zero-Order Controlled Delivery of Water-Insoluble Drugs. AAPS PharmSciTech 18:1, pages 82-92.
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Hiroyuki Yoshida, Akemi Kuwana, Hiroko Shibata, Ken-ichi Izutsu & Yukihiro Goda. (2016) Effects of Pump Pulsation on Hydrodynamic Properties and Dissolution Profiles in Flow-Through Dissolution Systems (USP 4). Pharmaceutical Research 33:6, pages 1327-1336.
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Hiroyuki Yoshida, Akemi Kuwana, Hiroko Shibata, Ken-ichi Izutsu & Yukihiro Goda. (2015) Particle Image Velocimetry Evaluation of Fluid Flow Profiles in USP 4 Flow-Through Dissolution Cells. Pharmaceutical Research 32:9, pages 2950-2959.
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Jozef Al-Gousous & Peter Langguth. (2015) Oral Solid Dosage Form Disintegration Testing — The Forgotten Test. Journal of Pharmaceutical Sciences 104:9, pages 2664-2675.
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Asma Radwan, Manfred Wagner, Gordon L. Amidon & Peter Langguth. (2014) Bio-predictive tablet disintegration: Effect of water diffusivity, fluid flow, food composition and test conditions. European Journal of Pharmaceutical Sciences 57, pages 273-279.
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C. Ferrero & M.R. Jiménez-Castellanos. (2014) In vitro release testing of matrices based on starch–methyl methacrylate copolymers: Effect of tablet crushing force, dissolution medium pH and stirring rate. International Journal of Pharmaceutics 461:1-2, pages 270-279.
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Anne Seidlitz & Werner Weitschies. (2012) In-vitro dissolution methods for controlled release parenterals and their applicability to drug-eluting stent testing. Journal of Pharmacy and Pharmacology 64:7, pages 969-985.
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G. Shiko, L.F. Gladden, A.J. Sederman, P.C. Connolly & J.M. Butler. (2011) MRI Studies of the Hydrodynamics in a USP 4 Dissolution Testing Cell. Journal of Pharmaceutical Sciences 100:3, pages 976-991.
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Emmanuel Scheubel, Marc Lindenberg, Eric Beyssac & Jean-Michel Cardot. (2010) Small Volume Dissolution Testing as a Powerful Method during Pharmaceutical Development. Pharmaceutics 2:4, pages 351-363.
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Saeed A Qureshi. (2004) Improved drug dissolution and product characterization using a crescent-shaped spindle. Journal of Pharmacy and Pharmacology 56:9, pages 1135-1141.
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Dave A. Miller, Mirko Gamba, Dorothea Sauer, Troy P. Purvis, Noel T. Clemens & Robert O. WilliamsIIIIII. (2007) Evaluation of the USP dissolution test method A for enteric-coated articles by planar laser-induced fluorescence. International Journal of Pharmaceutics 330:1-2, pages 61-72.
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Deirdre M. D’Arcy, Owen I. Corrigan & Anne Marie Healy. (2006) Evaluation of hydrodynamics in the basket dissolution apparatus using computational fluid dynamics—Dissolution rate implications. European Journal of Pharmaceutical Sciences 27:2-3, pages 259-267.
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Saeed A. Qureshi. (2004) Choice of rotation speed (rpm) for bio-relevant drug dissolution testing using a crescent-shaped spindle. European Journal of Pharmaceutical Sciences 23:3, pages 271-275.
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J Kukura, J.L Baxter & F.J Muzzio. (2004) Shear distribution and variability in the USP Apparatus 2 under turbulent conditions. International Journal of Pharmaceutics 279:1-2, pages 9-17.
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Brett Kralj & Robert A.W Dryfe. (2003) The rotating paddle cell. Electrochemistry Communications 5:4, pages 325-328.
Crossref

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