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Drug Development and Industrial Pharmacy Volume 28, 2002 - Issue 6
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Research Article

Determination of Steroid Hormones in Oral Contraceptives by High-Performance Liquid Chromatography

Maria Inês R. M. Santoro Departamento de Farmácia, Universidade de São Paulo, Faculdade de Ciências Farmacêuticas, Caixa Postal 66083, São Paulo, CEP 05315-970, Brazil
,
Nájla M. Kassab Departamento de Farmácia, Universidade de São Paulo, Faculdade de Ciências Farmacêuticas, Caixa Postal 66083, São Paulo, CEP 05315-970, Brazil
,
Maya Hasegawa Departamento de Farmácia, Universidade de São Paulo, Faculdade de Ciências Farmacêuticas, Caixa Postal 66083, São Paulo, CEP 05315-970, Brazil
&
Érika R. M. Kedor-Hackmann Departamento de Farmácia, Universidade de São Paulo, Faculdade de Ciências Farmacêuticas, Caixa Postal 66083, São Paulo, CEP 05315-970, Brazil
Pages 741-747 | Published online: 17 Jun 2002

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Bhaskara P. V. Mantena, Sumathi V. Rao, K. M. Ch. Appa Rao, K. Ramakrishna & S. P. Vittal. (2015) HPLC Method for Simultaneous Determination of Potential Impurities of Norgestimate and Ethinyl Estradiol in Combination Drug Product Using Sub-2 µm Column. Journal of Liquid Chromatography & Related Technologies 38:10, pages 1014-1025.
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Aleksandra Laban, Slavko Markovic, Milena Stankov & Predrag Djurdjevic. (2004) Simultaneous Determination of Gestodene and Ethinyl Estradiol in Contraceptive Formulations by RP‐HPLC. Analytical Letters 37:2, pages 273-282.
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Articles from other publishers (10)

Srinivasa Reddy Chinta, Vaishnavi Chintala, Vishnu Nandimalla, Rajyalakshmi Ch, Sasikiran Goud Ediga, Leela Prasad Kowtharapu & Naresh Kumar Katari. (2023) Quantification of Drospirenone and Ethinyl Estradiol Related Impurities in a Combined Pharmaceutical Dosage Form by Chromatography Method with QbD Robustness Study. Journal of AOAC International.
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Midhu George Veeran, Karthikeyan C.Bharaniraja B.Diksha Painuly & Abi Santhosh Aprem. (2021) RP-HPLC method validation for fast extraction and quantification of Levonorgestrel drug from silicone based intrauterine device intended for in-process and finished formulation. DARU Journal of Pharmaceutical Sciences 29:1, pages 185-193.
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Inas A. Abdallah, Dana C. Hammell, Hazem E. Hassan & Audra L. Stinchcomb. (2016) Norelgestromin/ethinyl estradiol intravenous infusion formulation optimization, stability and compatibility testing: A case study to overcome polysorbate 80 interference in chromatographic analysis. Journal of Pharmaceutical and Biomedical Analysis 125, pages 145-153.
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Viviane Benevenuti Silva, Angel Arturo Gaona Galdos, Cintia Maria Alves Mothe, Michele Bacchi Pallastrelli, Maria Segunda Aurora Prado, Anil Kumar Singh, Erika Rosa Maria Kedor-Hackmann & Maria Inês Rocha Miritello Santoro. (2013) Simultaneous determination of ethinyl estradiol and drospirenone in oral contraceptive by high performance liquid chromatography. Brazilian Journal of Pharmaceutical Sciences 49:3, pages 521-528.
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David Zamora & Marcelo Blanco. (2012) Improving the efficiency of ion mobility spectrometry analyses by using multivariate calibration. Analytica Chimica Acta 726, pages 50-56.
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T. A. Denisova, V. V. Chistyakov & N. P. Sadchikova. (2008) Quantitative estimation of components of combined hormonal contraceptives by HPLC. Pharmaceutical Chemistry Journal 42:5, pages 291-293.
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Valeria Tripodi, Sabrina Flor, Adriana Carlucci & Silvia Lucangioli. (2006) Simultaneous determination of natural and synthetic estrogens by EKC using a novel microemulsion. ELECTROPHORESIS 27:22, pages 4431-4438.
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Ali Reza Fakhari, Afshin Rajabi Khorrami & Mojtaba Shamsipur. (2006) Stability-indicating high-performance thin-layer chromatographic determination of levonorgestrel and ethinyloestradiol in bulk drug and in low-dosage oral contraceptives. Analytica Chimica Acta 572:2, pages 237-242.
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E.M. Ghoneim, H.S. El-Desoky & M.M. Ghoneim. (2006) Adsorptive cathodic stripping voltammetric assay of the estrogen drug ethinylestradiol in pharmaceutical formulation and human plasma at a mercury electrode. Journal of Pharmaceutical and Biomedical Analysis 40:2, pages 255-261.
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SÁndor GÖrÖg. (2004) Recent Advances in the Analysis of Steroid Hormones and Related Drugs. Analytical Sciences 20:5, pages 767-782.
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