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Drug Development and Industrial Pharmacy Volume 30, 2004 - Issue 1
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Research Article

Physicochemical and Mechanical Evaluation of a Novel High Density Grade of Silicified Microcrystalline Cellulose

D. Fraser Steele Pharmaceutical Technology Research Group, Department of Pharmacy and Pharmacology, University of Bath, Bath, BA2 7AY, UK
,
Michael Tobyn Pharmaceutical Technology Research Group, Department of Pharmacy and Pharmacology, University of Bath, Bath, BA2 7AY, UK
,
Stephen Edge Pharmaceutical Technology Research Group, Department of Pharmacy and Pharmacology, University of Bath, Bath, BA2 7AY, UK
,
Ansong Chen Pharmaceutical Technology Research Group, Department of Pharmacy and Pharmacology, University of Bath, Bath, BA2 7AY, UK
&
John N. Staniforth Pharmaceutical Technology Research Group, Department of Pharmacy and Pharmacology, University of Bath, Bath, BA2 7AY, UK
Pages 103-109 | Published online: 02 Feb 2004

Citations (11)

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Read on this site (4)

Veeran Gowda, Ritesh M. Pabari, John G. Kelly & Zebunnissa Ramtoola. (2015) Influence of Prosolv and Prosolv:Mannitol 200 direct compression fillers on the physicomechanical properties of atorvastatin oral dispersible tablets. Pharmaceutical Development and Technology 20:4, pages 394-400.
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C. M. Hentzschel, A. Sakmann & C. S. Leopold. (2012) Comparison of traditional and novel tableting excipients: Physical and compaction properties. Pharmaceutical Development and Technology 17:6, pages 649-653.
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John F. Gamble, Wing-Sin Chiu & Mike Tobyn. (2011) Investigation into the impact of sub-populations of agglomerates on the particle size distribution and flow properties of conventional microcrystalline cellulose grades. Pharmaceutical Development and Technology 16:5, pages 542-548.
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Jitka Mužíková & Petra Nováková. (2007) A Study of the Properties of Compacts from Silicified Microcrystalline Celluloses. Drug Development and Industrial Pharmacy 33:7, pages 775-781.
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Articles from other publishers (7)

Carl Allenspach, Peter Timmins, Shasad Sharif & Tamara Minko. (2020) Characterization of a novel hydroxypropyl methylcellulose (HPMC) direct compression grade excipient for pharmaceutical tablets. International Journal of Pharmaceutics 583, pages 119343.
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Sina Salimi, Rahmat Sotudeh-Gharebagh, Reza Zarghami, Siok Yee Chan & Kah Hay Yuen. (2019) Production of Nanocellulose and Its Applications in Drug Delivery: A Critical Review. ACS Sustainable Chemistry & Engineering 7:19, pages 15800-15827.
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Sayantan Chattoraj, Patrick Daugherity, Todd McDermott, Angela Olsofsky, Wyatt J. Roth & Mike Tobyn. (2018) Sticking and Picking in Pharmaceutical Tablet Compression: An IQ Consortium Review. Journal of Pharmaceutical Sciences 107:9, pages 2267-2282.
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Oluwabukola Mustafa & Cheng Shu Chaw. (2016) Silicified microcrystalline cellulose based pellets and their physicochemical properties. Journal of Applied Polymer Science 133:33.
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Xiao Hai Li, Li Jie Zhao, Ke Ping Ruan, Yi Feng, De Sheng Xu & Ke Feng Ruan. (2013) The application of factor analysis to evaluate deforming behaviors of directly compressed powders. Powder Technology 247, pages 47-54.
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John Rojas & Vijay Kumar. (2011) Comparative evaluation of silicified microcrystalline cellulose II as a direct compression vehicle. International Journal of Pharmaceutics 416:1, pages 120-128.
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D. Fraser Steele, R. Christian Moreton, John N. Staniforth, Paul M. Young, Michael J. Tobyn & Stephen Edge. (2008) Surface Energy of Microcrystalline Cellulose Determined by Capillary Intrusion and Inverse Gas Chromatography. The AAPS Journal 10:3, pages 494-503.
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