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Drug Development and Industrial Pharmacy Volume 30, 2004 - Issue 6
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Research Article

Effect of Formulation Composition on the Properties of Controlled Release Tablets Prepared by Roller Compaction

Madhusudan Hariharan Pfizer Global R&D, Pharmaceutical Sciences, Skokie, IllinoisUSA; Abbott Laboratories, Global Pharmaceutical Operations, North Chicago, Illinois, 60064, USA
, Ph.D.,
Christina Wowchuk Pfizer Global R&D, Pharmaceutical Sciences, Skokie, IllinoisUSA
,
Paul Nkansah Pfizer Global R&D, Pharmaceutical Sciences, Skokie, IllinoisUSA
&
Vishal K. Gupta Pfizer Global R&D, Pharmaceutical Sciences, Skokie, IllinoisUSA; Tyco HealthCare Mallinckrodt, Pharmaceutical R&D, St. Louis, MissouriUSA
Pages 565-572 | Published online: 03 Jun 2004

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Nathan Boersen, David Belair, Garnet E. Peck & Rodolfo Pinal. (2016) A dimensionless variable for the scale up and transfer of a roller compaction formulation. Drug Development and Industrial Pharmacy 42:1, pages 60-69.
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Nathan Boersen, M. Teresa Carvajal, Kenneth R. Morris, Garnet E. Peck & Rodolfo Pinal. (2015) The influence of API concentration on the roller compaction process: modeling and prediction of the post compacted ribbon, granule and tablet properties using multivariate data analysis. Drug Development and Industrial Pharmacy 41:9, pages 1470-1478.
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Josephine L. P. Soh, Feng Wang, Nathan Boersen, Rodolfo Pinal, Garnet E. Peck, M. Teresa Carvajal, James Cheney, Hedinn Valthorsson & Jim Pazdan. (2008) Utility of Multivariate Analysis in Modeling the Effects of Raw Material Properties and Operating Parameters on Granule and Ribbon Properties Prepared in Roller Compaction. Drug Development and Industrial Pharmacy 34:10, pages 1022-1035.
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Paul Nkansah, Sy-Juen Wu, Stephanie Sobotka, Ken Yamamoto & Zezhi J. Shao. (2008) A Novel Method for Estimating Solid Fraction of Roller-Compacted Ribbons. Drug Development and Industrial Pharmacy 34:2, pages 142-148.
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Articles from other publishers (14)

Yvonne Rosiaux, Vincent Jannin & Cécile Morin. 2022. Oral Drug Delivery for Modified Release Formulations. Oral Drug Delivery for Modified Release Formulations 205 213 .
Aleša Dular Vovko, Bor Hodžić, Tina Brec, Grega Hudovornik & Franc Vrečer. (2022) Influence of Formulation Factors, Process Parameters, and Selected Quality Attributes on Carvedilol Release from Roller-Compacted Hypromellose-Based Matrix Tablets. Pharmaceutics 14:4, pages 876.
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Hui Xu, Li Liu, Xuehui Li, Junyuan Ma, Rui Liu & Shaoning Wang. (2019) Extended tacrolimus release via the combination of lipid-based solid dispersion and HPMC hydrogel matrix tablets. Asian Journal of Pharmaceutical Sciences 14:4, pages 445-454.
Crossref
Johanna Heiman, Farhad Tajarobi, Bindhumadhavan Gururajan, Anne Juppo & Susanna Abrahmsén-Alami. (2014) Roller Compaction of Hydrophilic Extended Release Tablets—Combined Effects of Processing Variables and Drug/Matrix Former Particle Size. AAPS PharmSciTech 16:2, pages 267-277.
Crossref
Yvonne Rosiaux, Vincent Jannin, Sophie Hughes & Delphine Marchaud. 2015. Excipient Applications in Formulation Design and Drug Delivery. Excipient Applications in Formulation Design and Drug Delivery 237 271 .
Yvonne Rosiaux, Vincent Jannin, Sophie Hughes & Delphine Marchaud. (2014) Solid lipid excipients — Matrix agents for sustained drug delivery. Journal of Controlled Release 188, pages 18-30.
Crossref
Iyad Rashid, Mahmoud M. H. Al Omari & Adnan A. Badwan. (2013) From native to multifunctional starch-based excipients designed for direct compression formulation. Starch - Stärke 65:7-8, pages 552-571.
Crossref
Y. Takeuchi, M. Yoshida, A. Ito & H. Sunada. (2009) Uniformity of drug content during pharmaceutical dry granulating by roller compaction and tableting processes. Journal of Drug Delivery Science and Technology 19:2, pages 119-124.
Crossref
Garnet Peck, Josephine Soh & Kenneth Morris. 2008. Pharmaceutical Dosage Forms - Tablets. Pharmaceutical Dosage Forms - Tablets 303 336 .
Garnet Peck, Josephine Soh & Kenneth Morris. 2008. Pharmaceutical Dosage Forms - Tablets, Third Edition. Pharmaceutical Dosage Forms - Tablets, Third Edition 303 336 .
Chialu Kevin Chang, Fernando A. Alvarez–Nunez, Joseph V. Rinella, Lars-Erik Magnusson & Katsuhiko Sueda. (2008) Roller Compaction, Granulation and Capsule Product Dissolution of Drug Formulations Containing a Lactose or Mannitol Filler, Starch, and Talc. AAPS PharmSciTech 9:2, pages 597-604.
Crossref
Josephine L. P. Soh, Nathan Boersen, M. Teresa Carvajal, Kenneth R. Morris, Garnet E. Peck & Rodolfo Pinal. (2007) Importance of Raw Material Attributes for Modeling Ribbon and Granule Properties in Roller Compaction: Multivariate Analysis on Roll Gap and NIR Spectral Slope as Process Critical Control Parameters. Journal of Pharmaceutical Innovation 2:3-4, pages 106-124.
Crossref
Manoj N. Gambhire, Kshitij W. Ambade, Sushma D. Kurmi, Vilasrao J. Kadam & Kisan R. Jadhav. (2007) Development and in vitro evaluation of an oral floating matrix tablet formulation of diltiazem hydrochloride. AAPS PharmSciTech 8:3, pages E166-E174.
Crossref
N Anthony Armstrong. 2006. Pharmaceutical Experimental Design and Interpretation, 2nd Edition. Pharmaceutical Experimental Design and Interpretation, 2nd Edition 189 208 .

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