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Drug Development and Industrial Pharmacy Volume 31, 2005 - Issue 1
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Research Article

Evaluation of Different Fast Melting Disintegrants by Means of a Central Composite Design

Piera Di Martino Laboratorio di Tecnica Farmaceutica, Dipartimento di Scienze Chimiche, Via S. Agostino, Camerino, Italy; Laboratorio di Tecnica Farmaceutica, Dipartimento di Scienze Chimiche, Via S. Agostino, Camerino, Italy, 62032
,
Sante Martelli Laboratorio di Tecnica Farmaceutica, Dipartimento di Scienze Chimiche, Via S. Agostino, Camerino, Italy
&
Pascal Wehrlé Laboratoire de Pharmacotechnie, Faculté de Pharmacie, ULP Strasbourg I, 74, route du Rhin, Illkirch, France, BP 24F-67401
Pages 109-121 | Published online: 26 Sep 2008

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Kamran Zaheer & Peter Langguth. (2018) Formulation strategy towards minimizing viscosity mediated negative food effect on disintegration and dissolution of immediate release tablets. Drug Development and Industrial Pharmacy 44:3, pages 444-451.
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Piera Di Martino, Ledjan Malaj, Roberta Censi, Sante Martelli, Etienne Joiris & Christine Barthélémy. (2007) The Role of Several l-HPCs in Preventing Tablet Capping During Direct Compression of Metronidazole. Drug Development and Industrial Pharmacy 33:12, pages 1308-1317.
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Muhammad Tayyab, Muhammad Tahir Haseeb, Tariq G. Alsahli, Nisar Ul Khaliq, Muhammad Ajaz Hussain, Rabeea Khan, Ayesha Nawaz, Asif Iqbal, Abdullah Salah Alanazi & Syed Nasir Abbas Bukhari. (2024) Fabrication and optimization of febuxostat-loaded chitosan nanocarriers for better pharmacokinetics profile. International Journal of Biological Macromolecules 257, pages 128448.
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Ozge Didem Uluhan, Tugba Gulsun & Selma Sahin. (2023) Development and characterization of trimethobenzamide hydrochloride containing orally disintegrating tablets. Journal of Drug Delivery Science and Technology 88, pages 104980.
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Candela Juan, Daiana Rodriguez, Laura Ceballos, Carlos Lanusse, Loreana Gallo & Noelia Gonzalez Vidal. (2023) Development of ivermectin orally disintegrating tablets using factorial design: In-vitro evaluation and in vivo absorption pattern in rats. Journal of Drug Delivery Science and Technology 87, pages 104757.
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Lukmankhan S. Pathan, Chetna D. Modi, Mukesh C. Gohel, Nikita H. Udhwani, Vaishali T. Thakkar & Hardik B. Rana. (2022) Introducing novel hybridization technique for solubility enhancement of Bosentan formulation. Food Hydrocolloids for Health 2, pages 100055.
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Evelin Gutiérrez Moreno, José A. Rodriguez Ávila & Julián Cruz Borbolla. 2022. Quality Control Applications in the Pharmaceutical and Medical Device Manufacturing Industry. Quality Control Applications in the Pharmaceutical and Medical Device Manufacturing Industry 1 23 .
Vivek Dave, Renu Bala Yadav, Richa Ahuja & Sachdev Yadav. (2017) Formulation design and optimization of novel fast dissolving tablet of chlorpheniramine maleate by using lyophilization techniques. Bulletin of Faculty of Pharmacy, Cairo University 55:1, pages 31-39.
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P. Zarmpi, T. Flanagan, E. Meehan, J. Mann & N. Fotaki. (2017) Biopharmaceutical aspects and implications of excipient variability in drug product performance. European Journal of Pharmaceutics and Biopharmaceutics 111, pages 1-15.
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Tze Ning Hiew, Nur Atiqah Binte Johan, Parind Mahendrakumar Desai, Siang Meng Chua, Zhi Hui Loh & Paul Wan Sia Heng. (2016) Effect of moisture sorption on the performance of crospovidone. International Journal of Pharmaceutics 514:1, pages 322-331.
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Parind Mahendrakumar Desai, Celine Valeria Liew & Paul Wan Sia Heng. (2016) Review of Disintegrants and the Disintegration Phenomena. Journal of Pharmaceutical Sciences 105:9, pages 2545-2555.
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Parind Mahendrakumar Desai, Patrick Xuan Hua Er, Celine Valeria Liew & Paul Wan Sia Heng. (2014) Functionality of Disintegrants and Their Mixtures in Enabling Fast Disintegration of Tablets by a Quality by Design Approach. AAPS PharmSciTech 15:5, pages 1093-1104.
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Iyad Rashid, Mahmoud M. H. Al Omari & Adnan A. Badwan. (2013) From native to multifunctional starch-based excipients designed for direct compression formulation. Starch - Stärke 65:7-8, pages 552-571.
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Bhatu Badgujar & Atish Mundada. (2011) The technologies used for developing orally disintegrating tablets: A review. Acta Pharmaceutica 61:2, pages 117-139.
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Adamo Fini, Valentina Bergamante, Gian Carlo Ceschel, Celestino Ronchi & Carlos Alberto Fonseca de Moraes. (2008) Fast dispersible/slow releasing ibuprofen tablets. European Journal of Pharmaceutics and Biopharmaceutics 69:1, pages 335-341.
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H. Omidian & K. Park. (2008) Swelling agents and devices in oral drug delivery. Journal of Drug Delivery Science and Technology 18:2, pages 83-93.
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