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Research Article

CYTOCHROME P450-NULL MICE

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Pages 437-447 | Published online: 05 Dec 1999

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Diana M. E. Otto, Colin J. Henderson, Dianne Carrie, Megan Davey, Thomas E. Gundersen, Rune Blomhoff, Ralf H. Adams, Cheryll Tickle & C. Roland Wolf. (2003) Identification of Novel Roles of the Cytochrome P450 System in Early Embryogenesis: Effects on Vasculogenesis and Retinoic Acid Homeostasis. Molecular and Cellular Biology 23:17, pages 6103-6116.
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Sarrah L. Hannon & Xinxin Ding. 2022. Pharmacology and Toxicology of Cytochrome P450 – 60th Anniversary. Pharmacology and Toxicology of Cytochrome P450 – 60th Anniversary 253 284 .
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Alexa N. Carrera, Marianne K.O. Grant & Beshay N. Zordoky. (2020) CYP1B1 as a therapeutic target in cardio-oncology. Clinical Science 134:21, pages 2897-2927.
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Marten Michaelis, Alexander Sobczak, Dirk Koczan, Martina Langhammer, Norbert Reinsch, Jennifer Schoen & Joachim M. Weitzel. (2017) Selection for female traits of high fertility affects male reproductive performance and alters the testicular transcriptional profile. BMC Genomics 18:1.
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Fang Yang, Hong Yang, Aramandla Ramesh, J. Shawn Goodwin, Emmanuel U. Okoro & ZhongMao Guo. (2016) Overexpression of Catalase Enhances Benzo(a)pyrene Detoxification in Endothelial Microsomes. PLOS ONE 11:9, pages e0162561.
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Rebeca Santes-Palacios, Diego Ornelas-Ayala, Noel Cabañas, Ana Marroquín-Pérez, Alexis Hernández-Magaña, Sitlali del Rosario Olguín-Reyes, Rafael Camacho-Carranza & Jesús Javier Espinosa-Aguirre. (2016) Regulation of Human Cytochrome P4501A1 (hCYP1A1): A Plausible Target for Chemoprevention?. BioMed Research International 2016, pages 1-17.
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Rima Dada, Tanuj Dada, Muneeb A Faiq & Rizwana Qadri. (2016) CYP1B1-mediated Pathobiology of Primary Congenital Glaucoma. Journal of Current Glaucoma Practice 9:3, pages 77-80.
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Tajamul Hussain, Omar S. Al-Attas, Nasser M. Al-Daghri, Arif A. Mohammed, Edgard De Rosas, Shebl Ibrahim, Benjamin Vinodson, Mohammed G. Ansari & Khaled I. Alam El-Din. (2014) Induction of CYP1A1, CYP1A2, CYP1B1, increased oxidative stress and inflammation in the lung and liver tissues of rats exposed to incense smoke. Molecular and Cellular Biochemistry 391:1-2, pages 127-136.
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Yvonne Dempsie, Neil A. MacRitchie, Kevin White, Ian Morecroft, Audrey F. Wright, Margaret Nilsen, Lynn Loughlin, Kirsty M. Mair & Margaret R. MacLean. (2013) Dexfenfluramine and the oestrogen-metabolizing enzyme CYP1B1 in the development of pulmonary arterial hypertension. Cardiovascular Research 99:1, pages 24-34.
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K. White, A. K. Johansen, M. Nilsen, L. Ciuclan, E. Wallace, L. Paton, A. Campbell, I. Morecroft, L. Loughlin, J. D. McClure, M. Thomas, K. M. Mair & M. R. MacLean. (2012) Activity of the Estrogen-Metabolizing Enzyme Cytochrome P450 1B1 Influences the Development of Pulmonary Arterial Hypertension. Circulation 126:9, pages 1087-1098.
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T. Einem Lindeman, M. C. Poirier & R. L. Divi. (2011) The resveratrol analogue, 2,3',4,5'-tetramethoxystilbene, does not inhibit CYP gene expression, enzyme activity and benzo[a]pyrene-DNA adduct formation in MCF-7 cells exposed to benzo[a]pyrene. Mutagenesis 26:5, pages 629-635.
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M. C. Kowalczyk, Z. Walaszek, P. Kowalczyk, T. Kinjo, M. Hanausek & T. J. Slaga. (2009) Differential effects of several phytochemicals and their derivatives on murine keratinocytes in vitro and in vivo: implications for skin cancer prevention. Carcinogenesis 30:6, pages 1008-1015.
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Jui-Pin Wu, Louis W. Chang, Hsien-Tsung Yao, Han Chang, Hui-Ti Tsai, Ming-Hsien Tsai, Teng-Kuang Yeh & Pinpin Lin. (2009) Involvement of Oxidative Stress and Activation of Aryl Hydrocarbon Receptor in Elevation of CYP1A1 Expression and Activity in Lung Cells and Tissues by Arsenic: An In Vitro and In Vivo Study. Toxicological Sciences 107:2, pages 385-393.
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Andrea H. Devlin, Marie McIlroy, Hayley D. McKeen, Pramode Bonde, A.A. Carlos Menezes, Christine J. Swarbrick, Tracy Robson, David G. Hirst, F. Charles Campbell, James A. McGuigan & Stephanie R. McKeown. (2009) Cytochrome P450 1B1 expression in rat esophageal tumorigenesis promoted by gastric and duodenal reflux. Molecular Carcinogenesis 48:2, pages 110-117.
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Maureen K. Bunger, Edward Glover, Susan M. Moran, Jacqueline A. Walisser, Garet P. Lahvis, Erin L. Hsu & Christopher A. Bradfield. (2008) Abnormal Liver Development and Resistance to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Toxicity in Mice Carrying a Mutation in the DNA-Binding Domain of the Aryl Hydrocarbon Receptor. Toxicological Sciences 106:1, pages 83-92.
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Shanbeh Zienolddiny, Daniele Campa, Helge Lind, David Ryberg, Vidar Skaug, Lodve B. Stangeland, Federico Canzian & Aage Haugen. (2008) A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of non-small cell lung cancer in smokers. Carcinogenesis 29:6, pages 1164-1169.
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Nadine Dragin, Timothy P. Dalton, Marian L. Miller, Howard G. Shertzer & Daniel W. Nebert. (2006) For Dioxin-induced Birth Defects, Mouse or Human CYP1A2 in Maternal Liver Protects whereas Mouse CYP1A1 and CYP1B1 Are Inconsequential. Journal of Biological Chemistry 281:27, pages 18591-18600.
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Jeanine A. Harrigan, Barbara P. McGarrigle, Thomas R. Sutter & James R. Olson. (2006) Tissue specific induction of cytochrome P450 (CYP) 1A1 and 1B1 in rat liver and lung following in vitro (tissue slice) and in vivo exposure to benzo(a)pyrene. Toxicology in Vitro 20:4, pages 426-438.
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Ai-Ming Yu, Katsumi Fukamachi, Kristopher W. Krausz, Connie Cheung & Frank J. Gonzalez. (2005) Potential Role for Human Cytochrome P450 3A4 in Estradiol Homeostasis. Endocrinology 146:7, pages 2911-2919.
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Jerrold M. Ward, Nikolay P. Nikolov, Jolynne R. Tschetter, Jeffrey B. Kopp, Frank J. Gonzalez, Shioko Kimura & Richard M. Siegel. (2016) Progressive Glomerulonephritis and Histiocytic Sarcoma Associated with Macrophage Functional Defects in CYP1B1-Deficient Mice. Toxicologic Pathology 32:6, pages 710-718.
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B L Chang, S L Zheng, S D Isaacs, A Turner, G A Hawkins, K E Wiley, E R Bleecker, P C Walsh, D A Meyers, W B Isaacs & J Xu. (2003) Polymorphisms in the CYP1B1 gene are associated with increased risk of prostate cancer. British Journal of Cancer 89:8, pages 1524-1529.
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Haydn Prosser & Sohaila Rastan. (2003) Manipulation of the mouse genome: a multiple impact resource for drug discovery and development. Trends in Biotechnology 21:5, pages 224-232.
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Andreas Labedzki, Jeroen Buters, Wafaâ Jabrane & Uwe Fuhr. (2002) Differences in caffeine and paraxanthine metabolism between human and murine CYP1A2. Biochemical Pharmacology 63:12, pages 2159-2167.
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William F. Elmquist & Donald W. Miller. (2001) The use of transgenic mice in pharmacokinetic and pharmacodynamic studies. Journal of Pharmaceutical Sciences 90:4, pages 422-435.
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J L Raucy & S W Allen. (2001) Recent advances in P450 research. The Pharmacogenomics Journal 1:3, pages 178-186.
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P. J. Korytko, R. J. Maclntyre & J. G. Scott. (2001) Expression and activity of a house‐fly cytochrome P450, CYP6D1, in Drosophila melanogaster . Insect Molecular Biology 9:5, pages 441-449.
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Claudia Traidl, Hans F. Merk, Andrea Cavani & Nicolas Hunzelmann. (2000) New Insights into the Pathomechanisms of Contact Dermatitis by the Use of Transgenic Mouse Models. Skin Pharmacology and Physiology 13:6, pages 300-312.
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