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Drug Metabolism Reviews Volume 31, 1999 - Issue 3
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Research Article

DAMAGE AND REPAIR OF NERVE CELL DNA IN TOXIC STRESS*

GLEN E. KISBY Center for Research on Occupational and Environmental Toxicology, School of Medicine, Oregon Health Sciences University, 3181 S.W. Sam Jackson Park Road, Portland, Oregon, 97201, U.S.A.
,
HANS KABEL Center for Research on Occupational and Environmental Toxicology, School of Medicine, Oregon Health Sciences University, 3181 S.W. Sam Jackson Park Road, Portland, Oregon, 97201, U.S.A.
,
JACQUES HUGON Department of Histology and Cell Biology (ERS CNRS 6101), Faculty of Medicine, University of Limoges, Limoges, 87025, France
&
PETER SPENCER Center for Research on Occupational and Environmental Toxicology, School of Medicine, Oregon Health Sciences University, 3181 S.W. Sam Jackson Park Road, Portland, Oregon, 97201, U.S.A.
Pages 589-618 | Published online: 16 Aug 1999

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Shy‐Shin Chang, Yi‐Ling Chan, Ming‐Ling Wu, Jou‐Fang Deng, Te‐Fa Chiu, Jih‐Chang Chen, Feng‐Lin Wang & Ching‐Ping Tseng. (2004) Acute Cycas Seed Poisoning in Taiwan. Journal of Toxicology: Clinical Toxicology 42:1, pages 49-54.
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Articles from other publishers (42)

Katerina Menšíková, John C. Steele, Raymond Rosales, Carlo Colosimo, Peter Spencer, Annie Lannuzel, Yoshikazu Ugawa, Ryogen Sasaki, Santiago Giménez-Roldán, Radoslav Matej, Lucie Tuckova, Dominik Hrabos, Kristyna Kolarikova, Radek Vodicka, Radek Vrtel, Miroslav Strnad, Petr Hlustik, Pavel Otruba, Martin Prochazka, Martin Bares, Susana Boluda, Luc Buee, Gerhard Ransmayr & Petr Kaňovský. (2023) Endemic parkinsonism: clusters, biology and clinical features. Nature Reviews Neurology.
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Peter S. Spencer, Valerie S. Palmer, Glen E. Kisby, Emmeline Lagrange, B. Zane Horowitz, Raquel Valdes Angues, Jacques Reis, Jean-Paul Vernoux, Cédric Raoul & William Camu. (2023) Early-onset, conjugal, twin-discordant, and clusters of sporadic ALS: Pathway to discovery of etiology via lifetime exposome research. Frontiers in Neuroscience 17.
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Glen E. Kisby & Peter S. Spencer. (2021) Genotoxic Damage During Brain Development Presages Prototypical Neurodegenerative Disease. Frontiers in Neuroscience 15.
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Peter S. Spencer, Valerie S. Palmer & Glen E. Kisby. (2020) Western Pacific ALS-PDC: Evidence implicating cycad genotoxins. Journal of the Neurological Sciences 419, pages 117185.
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Carmel Armon. (2018) From Snow to Hill to ALS: An epidemiological odyssey in search of ALS causation. Journal of the Neurological Sciences 391, pages 134-140.
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Christopher A. Shaw. 2017. Neural Dynamics of Neurological Disease. Neural Dynamics of Neurological Disease 301 354 .
Peter S. Spencer, Valerie S. Palmer & Glen E. Kisby. (2016) Seeking environmental causes of neurodegenerative disease and envisioning primary prevention. NeuroToxicology 56, pages 269-283.
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Carmel Armon. (2016) Accrued somatic mutations (nucleic acid changes) trigger ALS: 2005-2015 update. Muscle & Nerve 53:6, pages 842-849.
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M.R. Vasko, B. Shariati & N. Zanville. 2016. DNA Repair in Cancer Therapy. DNA Repair in Cancer Therapy 383 428 .
Sofia M. Dibble, Yijuan Du & Anthony A. Grace. 2016. Modeling the Psychopathological Dimensions of Schizophrenia - From Molecules to Behavior. Modeling the Psychopathological Dimensions of Schizophrenia - From Molecules to Behavior 107 124 .
Ellen Fritsche, Henrik Alm, Jenny Baumann, Lieve Geerts, Helen Håkansson, Stefan Masjosthusmann & Hilda Witters. (2015) Literature review on in vitro and alternative Developmental Neurotoxicity (DNT) testing methods. EFSA Supporting Publications 12:4.
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Peter S. Spencer, C. Edwin Garner, Valerie S. Palmer & Glen E. Kisby. 2015. Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders. Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders 211 252 .
Katrin Hayess, Christian Riebeling, Ralph Pirow, Matthias Steinfath, Dana Sittner, Birgitta Slawik, Andreas Luch & Andrea E.M. Seiler. (2013) The DNT-EST: A predictive embryonic stem cell-based assay for developmental neurotoxicity testing in vitro. Toxicology 314:1, pages 135-147.
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Glen E. Kisby, Holly Moore & Peter S. Spencer. (2013) Animal models of brain maldevelopment induced by cycad plant genotoxins. Birth Defects Research Part C: Embryo Today: Reviews 99:4, pages 247-255.
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Amit S. Kalgutkar, Deepak Dalvie, R. Scott Obach & Dennis A. Smith. 2012. Reactive Drug Metabolites. Reactive Drug Metabolites 203 224 .
Djane Braz Duarte & Michael R. Vasko. 2012. DNA Repair in Cancer Therapy. DNA Repair in Cancer Therapy 283 299 .
Glen E. Kisby & Peter S. Spencer. (2011) Is Neurodegenerative Disease a Long-Latency Response to Early-Life Genotoxin Exposure?. International Journal of Environmental Research and Public Health 8:10, pages 3889-3921.
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Antonio Migheli. 2011. DNA Damage Detection In Situ, Ex Vivo, and In Vivo. DNA Damage Detection In Situ, Ex Vivo, and In Vivo 29 36 .
N.C. Burton, D.A. Johnson, J.-M. Lee, A.D. Kraft, M.J. Calkins, R.J. Jakel & J.A. Johnson. 2010. Comprehensive Toxicology. Comprehensive Toxicology 59 69 .
Vardan T. Karamyan & Robert C. Speth. (2008) Animal models of BMAA neurotoxicity: A critical review. Life Sciences 82:5-6, pages 233-246.
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Stefania Bassanini, Kerri Hallene, Giorgio Battaglia, Adele Finardi, Stefano Santaguida, Marilyn Cipolla & Damir Janigro. (2007) Early cerebrovascular and parenchymal events following prenatal exposure to the putative neurotoxin methylazoxymethanol. Neurobiology of Disease 26:2, pages 481-495.
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Glen E. Kisby, Antoinette Olivas, Melissa Standley, Xinfang Lu, Patrick Pattee, Jean O’Malley, Xiaorong Li, Juan Muniz & Srinavasa R. Nagalla. (2006) Genotoxicants Target Distinct Molecular Networks in Neonatal Neurons. Environmental Health Perspectives 114:11, pages 1703-1712.
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Mercedes F. Paredes, Guangnan Li, Omri Berger, Scott C. Baraban & Samuel J. Pleasure. (2006) Stromal-Derived Factor-1 (CXCL12) Regulates Laminar Position of Cajal-Retzius Cells in Normal and Dysplastic Brains. The Journal of Neuroscience 26:37, pages 9404-9412.
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Andreina Milano, Nicola Montesano Gesualdi, Raffaele Teperino, Franca Esposito, Sergio Cocozza & Paola Ungaro. (2005) Oxidative DNA Damage and Activation of c-Jun N-Terminal Kinase Pathway in Fibroblasts from Patients with Hereditary Spastic Paraplegia. Cellular and Molecular Neurobiology 25:8, pages 1245-1254.
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Carmel Armon. (2005) Acquired nucleic acid changes may trigger sporadic amyotrophic lateral sclerosis. Muscle & Nerve 32:3, pages 373-377.
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Stephen C. Bondy & Arezoo Campbell. (2005) Developmental neurotoxicology. Journal of Neuroscience Research 81:5, pages 605-612.
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David Dupret, Marie-Françoise Montaron, Elodie Drapeau, Catherine Aurousseau, Michel Le Moal, Pier-Vincenzo Piazza & Djoher Nora Abrous. (2005) Methylazoxymethanol acetate does not fully block cell genesis in the young and aged dentate gyrus. European Journal of Neuroscience 22:3, pages 778-783.
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Inna I. Kruman, Peter R. Mouton, Roland EmokpaeJrJr, Roy G. Cutler & Mark P. Mattson. (2005) Folate deficiency inhibits proliferation of adult hippocampal progenitors. NeuroReport 16:10, pages 1055-1059.
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G.E. Kisby, M. Standley, X. Lu, J. O'Malley, B. Lin, J. Muniz, N.L. Luo, P. Pattee, S.A. Back & S.R. Nagalla. (2005) Molecular networks perturbed in a developmental animal model of brain injury. Neurobiology of Disease 19:1-2, pages 108-118.
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S. Araneda, S. Pelloux, J.P. Radicella, J. Angulo, K. Kitahama, K. Gysling & M.I. Forray. (2005) 8-oxoguanine DNA glycosylase, but not Kin17 protein, is translocated and differentially regulated by estrogens in rat brain cells. Neuroscience 136:1, pages 135-146.
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Gale A Kleven, Laila Queral & Scott R Robinson. (2004) Prenatal methylazoxymethanol exposure alters evoked responses in fetal rats. Neurotoxicology and Teratology 26:5, pages 663-671.
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Arezoo Campbell & Stephen Bondy. 2004. Molecular Neurotoxicology. Molecular Neurotoxicology 107 121 .
F. Fonnum & E. A. Lock. (2003) The contributions of excitotoxicity, glutathione depletion and DNA repair in chemically induced injury to neurones: exemplified with toxic effects on cerebellar granule cells. Journal of Neurochemistry 88:3, pages 513-531.
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Christopher S Wallace, Jonathon Reitzenstein & Ginger S Withers. (2003) Diminished experience-dependent neuroanatomical plasticity: evidence for an improved biomarker of subtle neurotoxic damage to the developing rat brain.. Environmental Health Perspectives 111:10, pages 1294-1298.
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Carmel Armon. (2003) An Evidence-Based Medicine Approach to the Evaluation of the Role of Exogenous Risk Factors in Sporadic Amyotrophic Lateral Sclerosis. Neuroepidemiology 22:4, pages 217-228.
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Carmel Armon. 2003. Motor Neuron Disorders. Motor Neuron Disorders 167 205 .
P.J Brooks. (2002) DNA repair in neural cells: basic science and clinical implications. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 509:1-2, pages 93-108.
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Ruiben Feng, Claire Rampon, Ya-Ping Tang, David Shrom, Janice Jin, Maureen Kyin, Bryce Sopher, George M Martin, Seong-Hun Kim, Ronald B Langdon, Sangram S Sisodia & Joe Z Tsien. (2001) Deficient Neurogenesis in Forebrain-Specific Presenilin-1 Knockout Mice Is Associated with Reduced Clearance of Hippocampal Memory Traces. Neuron 32:5, pages 911-926.
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Chengbiao Lu, Weiming Fu & Mark P Mattson. (2001) Telomerase protects developing neurons against DNA damage-induced cell death. Developmental Brain Research 131:1-2, pages 167-171.
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Silvia Araneda, Nathalie Mermet, Thibault Verjat, Jaime Francisco Angulo & Juan Pablo Radicella. (2001) Expression of Kin17 and 8-OxoG DNA glycosylase in cells of rodent and quail central nervous system. Brain Research Bulletin 56:2, pages 139-146.
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Zhiping Liu & Lee J. Martin. (2016) Isolation of Mature Spinal Motor Neurons and Single-cell Analysis Using the Comet Assay of Early Low-level DNA Damage Induced In Vitro and In Vivo. Journal of Histochemistry & Cytochemistry 49:8, pages 957-972.
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Peter S. Spencer. 2000. Neurotoxic Factors in Parkinson’s Disease and Related Disorders. Neurotoxic Factors in Parkinson’s Disease and Related Disorders 1 16 .

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