155
Views
18
CrossRef citations to date
0
Altmetric
Research Article

WHAT MAKES P450s WORK? SEARCHES FOR ANSWERS WITH KNOWN AND NEW P450s*

, , , , , & show all
Pages 267-281 | Published online: 10 Oct 2000

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Slobodan Rendic. (2002) Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metabolism Reviews 34:1-2, pages 83-448.
Read now

Articles from other publishers (14)

H.M. Chandra Mouli, Adithya Vinod, Shikha Kumari, Amit K. Tiwari, M.K. Kathiravan, V. Ravichandiran & Ramalingam Peraman. (2023) Deuterated driven new chemical entities: An optimistic way to improve therapeutic efficacy. Bioorganic Chemistry 135, pages 106490.
Crossref
Lydia Benkaidali, François André, Gautier Moroy, Bahoueddine Tangour, François Maurel & Michel Petitjean. (2019) Four Major Channels Detected in the Cytochrome P450 3A4: A Step toward Understanding Its Multispecificity. International Journal of Molecular Sciences 20:4, pages 987.
Crossref
Line Zurkinden, Dmitri Sviridov, Bruno Vogt & Geneviève Escher. (2018) Sterol 27-hydroxylase gene dosage and the antiatherosclerotic effect of Rifampicin in mice. Bioscience Reports 38:1.
Crossref
Thomas G. Gant. (2013) Using Deuterium in Drug Discovery: Leaving the Label in the Drug. Journal of Medicinal Chemistry 57:9, pages 3595-3611.
Crossref
Helena Líbalová, Kateřina Uhlířová, Jiří Kléma, Miroslav Machala, Radim J Šrám, Miroslav Ciganek & Jan Topinka. (2012) Global gene expression changes in human embryonic lung fibroblasts induced by organic extracts from respirable air particles. Particle and Fibre Toxicology 9:1.
Crossref
Igor Shamovsky, Lena Ripa, Lena Börjesson, Christine Mee, Bo Nordén, Peter Hansen, Catrin Hasselgren, Mike O’Donovan & Peter Sjö. (2011) Explanation for Main Features of Structure–Genotoxicity Relationships of Aromatic Amines by Theoretical Studies of Their Activation Pathways in CYP1A2. Journal of the American Chemical Society 133:40, pages 16168-16185.
Crossref
Sean C Gay, Arthur G Roberts & James R Halpert. (2010) Structural features of cytochromes P450 and ligands that affect drug metabolism as revealed by x-ray crystallography and NMR. Future Medicinal Chemistry 2:9, pages 1451-1468.
Crossref
Patrik Rydberg, Poongavanam Vasanthanathan, Chris Oostenbrink & Lars Olsen. (2009) Fast Prediction of Cytochrome P450 Mediated Drug Metabolism. ChemMedChem 4:12, pages 2070-2079.
Crossref
K.E. Janak. 2007. Comprehensive Organometallic Chemistry III. Comprehensive Organometallic Chemistry III 541 571 .
Ragulan Ramanathan, Swapan K. Chowdhury & Kevin B. Alton. 2005. Identification and Quantification of Drugs, Metabolites and Metabolizing Enzymes by LC-MS. Identification and Quantification of Drugs, Metabolites and Metabolizing Enzymes by LC-MS 225 276 .
Thomas Kraemer, Thomas Pflugmann, Michael Bossmann, Nicole M Kneller, Frank T Peters, Liane D Paul, Dietmar Springer, Roland F Staack & Hans H Maurer. (2004) Fenproporex N-dealkylation to amphetamine—enantioselective in vitro studies in human liver microsomes as well as enantioselective in vivo studies in Wistar and Dark Agouti rats. Biochemical Pharmacology 68:5, pages 947-957.
Crossref
Rita Bernhardt. 2004. Encyclopedia of Biological Chemistry. Encyclopedia of Biological Chemistry 544 549 .
Guang Yao, Eric B. Harstad & Christopher A. Bradfield. 2003. PAS Proteins: Regulators and Sensors of Development and Physiology. PAS Proteins: Regulators and Sensors of Development and Physiology 149 182 .
Suchitra Banerjee, Tanya Q. Shang, Angela M. Wilson, Allison L. Moore, Stuart E. Strand, Milton P. Gordon & Sharon Lafferty Doty. (2002) Expression of functional mammalian P450 2E1 in hairy root cultures. Biotechnology and Bioengineering 77:4, pages 462-466.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.