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Original Articles

Immunomodulating Activities of Ganoderma, a Mushroom with Medicinal Properties

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Pages 123-161 | Published online: 06 Feb 2007

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Jing-Xia Shi, Guo-Yu Chen, Qian Sun, Shi-Yang Meng & Wei-Qun Chi. (2022) Antimicrobial lanostane triterpenoids from the fruiting bodies of Ganoderma applanatum. Journal of Asian Natural Products Research 24:11, pages 1001-1007.
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Mario Forzan, Maria Irene Pacini, Pamela Bonaccini & Maurizio Mazzei. (2022) Antiviral effect of a commercially phytotherapeutic compound against feline immunodeficiency virus. Natural Product Research 36:16, pages 4159-4164.
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Yu Chen, Jie Gao, Qibin Chen, Wei Liu, Yanru Qi, Haji Akber Aisa & Tao Yuan. (2021) Applanaic acids A–C, three new highly oxygenated lanostane triterpenoids from the fruiting bodies of Ganoderma applanatum. Natural Product Research 35:21, pages 3918-3924.
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Zheng-Wei Cui, Shi-Ying Xu, Da-Wen Sun & Wei Chen. (2006) Dehydration of Concentrated Ganoderma lucidum Extraction by Combined Microwave-Vacuum and Conventional Vacuum Drying. Drying Technology 24:5, pages 595-599.
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John W. M. Yuen & Mayur Danny I. Gohel. (2005) Anticancer Effects of Ganoderma lucidum: A Review of Scientific Evidence. Nutrition and Cancer 53:1, pages 11-17.
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Yihuai Gao, He Gao, Eli Chan, Wenbo Tang, Xiaotian Li, Jun Liang & Shufeng Zhou. (2005) Protective Effect of Ganoderma (a Mushroom with Medicinal Properties) Against Various Liver Injuries. Food Reviews International 21:1, pages 27-52.
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Articles from other publishers (40)

Mohammed Sharif Swallah, Precious Bondzie-Quaye, Han Wang, Chang-Sheng Shao, Pei Hua, Mona Alrasheed Bashir, Joseph Benjamin Holman, Frederick Leo Sossah & Qing Huang. (2023) Potentialities of Ganoderma lucidum extracts as functional ingredients in food formulation. Food Research International 172, pages 113161.
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Katarzyna Sułkowska-Ziaja, Monika Balik, Andrzej Szczepkowski, Monika Trepa, Gokhan Zengin, Katarzyna Kała & Bożena Muszyńska. (2023) A Review of Chemical Composition and Bioactivity Studies of the Most Promising Species of Ganoderma spp.. Diversity 15:8, pages 882.
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Poonam RahangdaleA. M. WankhadeJ. V. VyasV. V. Paithnakar. (2023) A Review on Management of Varius Disease by Traditional Chinese Medicine Ganoderma lucidum. Research Journal of Pharmacognosy and Phytochemistry, pages 167-172.
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Isabel Barbosa, Cátia Domingues, Rui M. Barbosa & Fernando Ramos. (2022) Amanitins in Wild Mushrooms: The Development of HPLC-UV-EC and HPLC-DAD-MS Methods for Food Safety Purposes. Foods 11:23, pages 3929.
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Afifa, Nazim Hussain, Zulqarnain Baqar, Mehvish Mumtaz, Ahmed H. El-Sappah, Pau Loke Show, Hafiz M.N. Iqbal, Sunita Varjani & Muhammad Bilal. (2022) Bioprospecting fungal-derived value-added bioproducts for sustainable pharmaceutical applications. Sustainable Chemistry and Pharmacy 29, pages 100755.
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Xiong Gao, Ranhua Zeng, Jiayi Qi, Chi-Tang Ho, Bin Li, Zhongzheng Chen, Shaodan Chen, Chun Xiao, Huiping Hu, Manjun Cai, Yizhen Xie & Qingping Wu. (2022) Immunoregulatory activity of a low-molecular-weight heteropolysaccharide from Ganoderma leucocontextum fruiting bodies in vitro and in vivo. Food Chemistry: X 14, pages 100321.
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Aly Farag El El Sheikha. (2022) Nutritional Profile and Health Benefits of Ganoderma lucidum “Lingzhi, Reishi, or Mannentake” as Functional Foods: Current Scenario and Future Perspectives. Foods 11:7, pages 1030.
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Elena Vetchinkina, Alexander Fomin, Nikita Navolokin & Alexander Shirokov. (2022) Proteins and polysaccharides from vegetative mycelium of medicinal basidiomycete Lentinus edodes display cytotoxicity towards human and animal cancer cell lines. International Journal of Biological Macromolecules 195, pages 398-411.
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H. M. Akshay Kumar, Mehulee Sarkar, K. Darshan, Thungri Ghoshal, B. S. Kavya, Bishnu Maya Bashayl, A. J. K. Asaiya & Nanitha Berry. 2022. Fungal diversity, ecology and control management. Fungal diversity, ecology and control management 255 291 .
Boris Jakopovic, Nada Oršolić & Ivan Jakopovich. (2021) Proteomic Research on the Antitumor Properties of Medicinal Mushrooms. Molecules 26:21, pages 6708.
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Akindele Oluwatosin Adeyi, Shakirat Adedoyin Awosanya, Olubisi Esther Adeyi, Adewale Segun James & Clementina Oyinkansola Adenipekun. (2021) Ganoderma lucidum ethanol extract abrogates metabolic syndrome in rats: In vivo evaluation of hypoglycemic, hypolipidemic, hypotensive and antioxidant properties. Obesity Medicine 22, pages 100320.
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Óscar J. Sánchez & Sandra Montoya. (2020) Assessment of Polysaccharide and Biomass Production from Three White-Rot Fungi by Solid-State Fermentation Using Wood and Agro-Industrial Residues: A Kinetic Approach. Forests 11:10, pages 1055.
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Mengxi Ying, Bing Zheng, Qiang Yu, Kunyou Hou, Hui Wang, Mingming Zhao, Yi Chen, Jianhua Xie, Shaoping Nie & Mingyong Xie. (2020) Ganoderma atrum polysaccharide ameliorates intestinal mucosal dysfunction associated with autophagy in immunosuppressed mice. Food and Chemical Toxicology 138, pages 111244.
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Insha Zahoor, Nadira Anjum, Ishfaq Hamid Dar & Shafaq Javid. 2020. Antioxidants in Vegetables and Nuts - Properties and Health Benefits. Antioxidants in Vegetables and Nuts - Properties and Health Benefits 265 289 .
Banani Das, Biplab De, Rishiraj Chetree & Subhash C. Mandal. 2020. Herbal Medicine in India. Herbal Medicine in India 509 532 .
Purva Sharma, Rajkumar Tulsawani & Usha Agrawal. (2019) Pharmacological effects of Ganoderma lucidum extract against high‐altitude stressors and its subchronic toxicity assessment . Journal of Food Biochemistry 43:12.
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Maryna Sukhomlyn, Vitaliia Didenko, Nadiia Tsvyd & Yurii Petrychuk. (2019) Initiation of Basidioma Formation of Rare and Medicinal Macromycetes in Pure Culture. Lesya Ukrainka Eastern European National University Scientific Bulletin. Series: Biological Sciences:3, pages 17-25.
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Zhuo Du, Cai-Hong Dong, Ke Wang & Yi-Jian Yao. 2019. Ganoderma and Health. Ganoderma and Health 15 58 .
Yu Cao, Xiaowei Xu, Shujing Liu, Linfang Huang & Jian Gu. (2018) Ganoderma: A Cancer Immunotherapy Review. Frontiers in Pharmacology 9.
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Nur Amalina Amirullah, Nurhayati Zainal Abidin & Noorlidah Abdullah. (2018) The potential applications of mushrooms against some facets of atherosclerosis: A review. Food Research International 105, pages 517-536.
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Shaoping Nie, Steve W. Cui & Mingyong Xie. 2018. Bioactive Polysaccharides. Bioactive Polysaccharides 205 294 .
Faruck L. Hakkim, Mohammed Al-Buloshi & Jackson Achankunju. (2016) Chemical composition and anti-proliferative effect of Oman's Ganoderma applanatum on breast cancer and cervical cancer cells. Journal of Taibah University Medical Sciences 11:2, pages 145-151.
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Xiyun Sun, Ning Liu, Zhaoxia Wu, Ying Feng & Xianjun Meng. (2015) Anti-Tumor Activity of a Polysaccharide from Blueberry. Molecules 20:3, pages 3841-3853.
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C. F. Song, S. G. Wang, J. Yang, Z. W. Cui & Y. H. Gu. (2015) Optimization of Vacuum-Microwave Radiation Pretreatment on Extraction of Ganoderma Polysaccharides . Mathematical Problems in Engineering 2015, pages 1-6.
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Ding Zhao, Ming-Wei Chang, Jing-Song Li, William Suen & Jie Huang. (2014) Investigation of Ice-Assisted Sonication on the Microstructure and Chemical Quality of Ganoderma lucidum Spores . Journal of Food Science 79:11, pages E2253-E2265.
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Hui Zhang, Shao-Ping Nie, Jun-Yi Yin, Yuan-Xing Wang & Ming-Yong Xie. (2014) Structural characterization of a heterogalactan purified from fruiting bodies of Ganoderma atrum. Food Hydrocolloids 36, pages 339-347.
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Adrian Wiater, Roman Paduch, Adam Choma, Małgorzata Pleszczyńska, Marek Siwulski, Jolanta Dominik, Grzegorz Janusz, Michał Tomczyk & Janusz Szczodrak. (2012) Biological study on carboxymethylated (1→3)-α-d-glucans from fruiting bodies of Ganoderma lucidum. International Journal of Biological Macromolecules 51:5, pages 1014-1023.
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Emmanuel Ibukunoluwa Moyin-Jesu, C. S. Iyoha & M. O. Akinola. (2012) Comparative Evaluation of Different Organic Media on Soil Chemical Composition, Growth, and Yield of Mushroom ( Pleurotus tubergium L.) . ISRN Agronomy 2012, pages 1-7.
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Dilani D. De Silva, Sylvie Rapior, Françoise Fons, Ali H. Bahkali & Kevin D. Hyde. (2012) Medicinal mushrooms in supportive cancer therapies: an approach to anti-cancer effects and putative mechanisms of action. Fungal Diversity 55:1, pages 1-35.
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Hui Zhang, Wen-Juan Li, Shao-Ping Nie, Yi Chen, Yuan-Xing Wang & Ming-Yong Xie. (2012) Structural characterisation of a novel bioactive polysaccharide from Ganoderma atrum. Carbohydrate Polymers 88:3, pages 1047-1054.
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Wen-Juan Li, Shao-Ping Nie, Ming-Yong Xie, Qiang Yu, Yi Chen & Ming He. (2011) Ganoderma atrum polysaccharide attenuates oxidative stress induced by d-galactose in mouse brain. Life Sciences 88:15-16, pages 713-718.
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Wen-Juan Li, Yi Chen, Shao-Ping Nie, Ming-Yong Xie, Ming He, Shen-Shen Zhang & Ke-Xue Zhu. (2011) Ganoderma atrum polysaccharide induces anti-tumor activity via the mitochondrial apoptotic pathway related to activation of host immune response. Journal of Cellular Biochemistry 112:3, pages 860-871.
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I. Leskosek-Cukalovic, S. Despotovic, N. Lakic, M. Niksic, V. Nedovic & V. Tesevic. (2010) Ganoderma lucidum — Medical mushroom as a raw material for beer with enhanced functional properties. Food Research International 43:9, pages 2262-2269.
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Chia-Jui Weng & Gow-Chin Yen. (2010) The in vitro and in vivo experimental evidences disclose the chemopreventive effects of Ganoderma lucidum on cancer invasion and metastasis. Clinical & Experimental Metastasis 27:5, pages 361-369.
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Vincent E. C. Ooi. 2008. Mushrooms as Functional Foods. Mushrooms as Functional Foods 147 198 .
Yong‐Tae Jeong, Byung‐Keun Yang, Sang‐Chul Jeong, Sang‐Min Kim & Chi‐Hyun Song. (2008) Ganoderma applanatum : a promising mushroom for antitumor and immunomodulating activity . Phytotherapy Research 22:5, pages 614-619.
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Yi Chen, Ming-Yong Xie, Shao-Ping Nie, Chang Li & Yuan-Xing Wang. (2008) Purification, composition analysis and antioxidant activity of a polysaccharide from the fruiting bodies of Ganoderma atrum. Food Chemistry 107:1, pages 231-241.
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Joseph D. Connolly & Robert A. Hill. (2007) Triterpenoids. Natural Product Reports 24:2, pages 465.
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Wenbo TangYihuai GaoGuoliang ChenHe GaoXihu DaiJinxian YeEli ChanMin HuangShufeng Zhou. (2005) A Randomized, Double-Blind and Placebo-Controlled Study of a Ganoderma lucidum Polysaccharide Extract in Neurasthenia . Journal of Medicinal Food 8:1, pages 53-58.
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Yihuai GaoWenbo TangHe GaoEli ChanJin LanShufeng Zhou. (2004) Ganoderma lucidum Polysaccharide Fractions Accelerate Healing of Acetic Acid-Induced Ulcers in Rats . Journal of Medicinal Food 7:4, pages 417-421.
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