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Original Articles

Spices as Beneficial Hypolipidemic Food Adjuncts: A Review

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Pages 187-220 | Published online: 06 Feb 2007

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (8)

Ozgur Ozalp, Z. Pinar Gumus & Mustafa Soylak. (2023) Magnetic solid-phase extraction of atrazine with ACC@NiCo2O4@Fe3O4 nanocomposite in spice and water samples. Separation Science and Technology 58:5, pages 916-928.
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Xin Jian Lei, Hyeok Min Yun, Jung Sun Kang & In Ho Kim. (2018) Effects of Herbiotic FS supplementation on growth performance, nutrient digestibility, blood profiles, and faecal scores in weanling pigs. Journal of Applied Animal Research 46:1, pages 702-706.
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Krishnapura Srinivasan. (2017) Anti-cholelithogenic potential of dietary spices and their bioactives. Critical Reviews in Food Science and Nutrition 57:8, pages 1749-1758.
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T Deprem, Se Yıldız, Ek Sari, Sa Bingol, Sk Tasci, S Aslan, M Sozmen & G Nur. (2015) Distribution of glutathione peroxidase 1 in liver tissues of healthy and diabetic rats treated with capsaisin. Biotechnic & Histochemistry 90:1, pages 1-7.
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Masood Sadiq Butt, Imran Pasha, Muhammad Tauseef Sultan, Muhammad Atif Randhawa, Farhan Saeed & Waqas Ahmed. (2013) Black Pepper and Health Claims: A Comprehensive Treatise. Critical Reviews in Food Science and Nutrition 53:9, pages 875-886.
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K. Srinivasan. (2006) Fenugreek (Trigonella foenum-graecum): A Review of Health Beneficial Physiological Effects. Food Reviews International 22:2, pages 203-224.
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K. Srinivasan. (2005) Role of Spices Beyond Food Flavoring: Nutraceuticals with Multiple Health Effects. Food Reviews International 21:2, pages 167-188.
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Articles from other publishers (54)

Rositta Varghese & J.G. Ray. (2023) Sustainable agriculture of tropical spices: arbuscular mycorrhizal fungi as an ecotechnological tool − A critical review. Journal of Applied Research on Medicinal and Aromatic Plants 36, pages 100507.
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E. Malematja, T. G. Manyelo, J. W. Ng’ambi, M. F. D. Nemauluma & S. D. Kolobe. (2023) Effects of onion extracts (Allium cepa) inclusion in diets on growth performance, carcass characteristics, and bone morphometric of broiler chickens. Animal Bioscience 36:7, pages 1075-1082.
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Sarah Elizabeth Prakash, Vaishnavi Chikkamagalur Manjunatha, Praveen Nagella & Vasantha Veerappa Lakshmaiah. 2023. Nutraceuticals. Nutraceuticals 269 291 .
Abdur Rauf, Muhammad Akram, Hina Anwar, Muhammad Daniyal, Naveed Munir, Sami Bawazeer, Saud Bawazeer, Maksim Rebezov, Abdelhakim Bouyahya, Mohammad Ali Shariati, Muthu Thiruvengadam, Orynzhamal Sarsembenova, Yahia N. Mabkhot, Mohammad Nazmul Islam, Talha Bin Emran, Sergey Hodak, Gokhan Zengin & Haroon Khan. (2022) Therapeutic potential of herbal medicine for the management of hyperlipidemia: latest updates. Environmental Science and Pollution Research 29:27, pages 40281-40301.
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Takashi Kuroiwa & Yoshiki Higuchi. (2022) One-Step Encapsulation of Capsaicin into Chitosan–Oleic Acid Complex Particles: Evaluation of Encapsulation Ability and Stability. Polymers 14:11, pages 2163.
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Adeyemi Ojutalayo Adeeyo, Tshianeo Mellda Ndou, Mercy Adewumi Alabi, Hosana Dumisani Mkoyi, Erinfolami Motunrayo Enitan, Daniso Beswa, Rachel Makungo & John O. Odiyo. 2021. Herbs and Spices - New Processing Technologies. Herbs and Spices - New Processing Technologies.
Poonam Kulyal, Satyabrata Acharya, Aditya B. Ankari, Praveen K. Kokkiripati, Sarada D. Tetali & Agepati S. Raghavendra. (2021) Variable Secondary Metabolite Profiles Across Cultivars of Curcuma longa L. and C. aromatica Salisb.. Frontiers in Pharmacology 12.
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M. Esteki, M.J. Cardador, N. Jurado-Campos, A. Martín-Gómez, L. Arce & J. Simal-Gandara. 2021. Innovative Food Analysis. Innovative Food Analysis 181 248 .
Adedayo O. Ademiluyi, Olubukola H. Oyeniran & Ganiyu Oboh. (2020) Tropical Food Spices: A Promising Panacea for the Novel Coronavirus Disease (COVID‐19). eFood 1:5, pages 347-356.
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Guilherme B.L. De Freitas, Durinézio J. De Almeida, Emerson Carraro, Ivo I. Kerppers, Guilherme A.G. Martins, Rubiana M. Mainardes, Najeh M. Khalil & Iara J.T. Messias-Reason. (2018) Formulation, characterization, and in vitro/in vivo studies of capsaicin-loaded albumin nanoparticles. Materials Science and Engineering: C 93, pages 70-79.
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Mary Gulumian, Ewura Seidu Yahaya & Vanessa Steenkamp. (2018) African Herbal Remedies with Antioxidant Activity: A Potential Resource Base for Wound Treatment. Evidence-Based Complementary and Alternative Medicine 2018, pages 1-58.
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Keith W. Singletary. (2017) Fenugreek. Nutrition Today 52:2, pages 93-111.
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Sneha Jagtap, Pragyanshu Khare, Priyanka Mangal, Kanthi Kiran Kondepudi, Mahendra Bishnoi & Kamlesh Kumar Bhutani. (2017) Effect of mahanimbine, an alkaloid from curry leaves, on high-fat diet-induced adiposity, insulin resistance, and inflammatory alterations. BioFactors 43:2, pages 220-231.
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Muwen Lu, Chi-Tang Ho & Qingrong Huang. (2017) Extraction, bioavailability, and bioefficacy of capsaicinoids. Journal of Food and Drug Analysis 25:1, pages 27-36.
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Puttaswamy Mukthamba & Krishnapura Srinivasan. (2016) Hypolipidemic and antioxidant effects of dietary fenugreek (Trigonella foenum-graecum) seeds and garlic (Allium sativum) in high-fat fed rats. Food Bioscience 14, pages 1-9.
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Marcela Klimešová, Jiří­ Horáček, Michal Ondřej, Ivan Manga, Ivana Koláčková, Ludmila Nejeschlebová & Antoní­n Poní­žil. (2015) Microbial contamination of spices used in production of meat products. Potravinarstvo Slovak Journal of Food Sciences 9:1, pages 154-159.
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Puttaswamy Mukthamba & Krishnapura Srinivasan. (2014) Beneficial hypolipidemic influence of a combination of dietary fenugreek (Trigonella foenum-graecum) seeds and garlic (Allium sativum) in induced hypercholesterolemic rats. European Food Research and Technology 240:5, pages 1049-1058.
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B. K. An, J. Y. Kim, S. T. Oh, C. W. Kang, S. Cho & S. K. Kim. (2014) Effects of Onion Extracts on Growth Performance, Carcass Characteristics and Blood Profiles of White Mini Broilers. Asian-Australasian Journal of Animal Sciences 28:2, pages 247-251.
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Suhaila Mohamed. (2014) Functional foods against metabolic syndrome (obesity, diabetes, hypertension and dyslipidemia) and cardiovasular disease. Trends in Food Science & Technology 35:2, pages 114-128.
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Won-Jae Song, Hye-Jung Sung, Sung-Youn Kim, Kwang-Pyo Kim, Sangryeol Ryu & Dong-Hyun Kang. (2014) Inactivation of Escherichia coli O157:H7 and Salmonella Typhimurium in black pepper and red pepper by gamma irradiation. International Journal of Food Microbiology 172, pages 125-129.
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S.T. Hasan, J.-M. Zingg, P. Kwan, T. Noble, D. Smith & M. Meydani. (2014) Curcumin modulation of high fat diet-induced atherosclerosis and steatohepatosis in LDL receptor deficient mice. Atherosclerosis 232:1, pages 40-51.
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M.S. Mekha, R.I. Shobha, C.U. Rajeshwari & B. Andallu. 2014. Aging. Aging 233 245 .
Akram Mohammadi, Amirhossein Sahebkar, Mehrdad Iranshahi, Maral Amini, Roshanak Khojasteh, Majid Ghayour-Mobarhan & Gordon A. Ferns. (2013) Effects of Supplementation with Curcuminoids on Dyslipidemia in Obese Patients: A Randomized Crossover Trial. Phytotherapy Research 27:3, pages 374-379.
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Ekeanyanwu, R.C.. (2013) Evaluation of the Crude Protein and Amino Acid Composition of Nigerian Monodora myristica (Ehuru). Pakistan Journal of Nutrition 12:3, pages 219-223.
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Krishnapura Srinivasan. (2013) Dietary spices as beneficial modulators of lipid profile in conditions of metabolic disorders and diseases. Food & Function 4:4, pages 503.
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Jean-Marc Zingg, Syeda T. Hasan & Mohsen Meydani. (2013) Molecular mechanisms of hypolipidemic effects of curcumin. BioFactors 39:1, pages 101-121.
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Shubhra Pande & Krishnapura Srinivasan. (2012) Potentiation of Hypolipidemic and Weight-Reducing Influence of Dietary Tender Cluster Bean (Cyamopsis tetragonoloba) When Combined with Capsaicin in High-Fat-Fed Rats. Journal of Agricultural and Food Chemistry 60:33, pages 8155-8162.
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Shubhra Pande & Krishnapura Srinivasan. (2012) Potentiation of the hypolipidemic influence of dietary tender cluster bean (Cyamopsis tetragonoloba) by garlic in cholesterol fed rats. Food Chemistry 133:3, pages 798-805.
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Memy H Hassan, Mohamed Edfawy, Ahmed Mansour & Abdel-Aziz Hamed. (2011) Antioxidant and antiapoptotic effects of capsaicin against carbon tetrachloride-induced hepatotoxicity in rats. Toxicology and Industrial Health 28:5, pages 428-438.
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A. Kurian. 2012. Handbook of Herbs and Spices. Handbook of Herbs and Spices 72 88 .
Fernández-López Juana, Pérez-Alvarez José Angel & Viuda-Martos Manuel. 2012. Studies in Natural Products Chemistry Volume 37. Studies in Natural Products Chemistry Volume 37 115 134 .
RAGHUNATHA R. L. REDDY & KRISHNAPURA SRINIVASAN. (2011) HEPATOPROTECTIVE AND ANTIOXIDANT EFFECT OF FENUGREEK (TRIGONELLA FOENUM-GRAECUM) SEEDS IN MICE UNDER LITHOGENIC CONDITION. Journal of Food Biochemistry 35:6, pages 1619-1626.
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L. Yan, Q.W. Meng & I.H. Kim. (2011) The effect of an herb extract mixture on growth performance, nutrient digestibility, blood characteristics and fecal noxious gas content in growing pigs. Livestock Science 141:2-3, pages 143-147.
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Raghunatha R. L. Reddy & Krishnapura Srinivasan. (2011) Dietary fenugreek and onion attenuate cholesterol gallstone formation in lithogenic diet-fed mice. International Journal of Experimental Pathology 92:5, pages 308-319.
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Ki Sung Kang, Satowa Yahashi, Morio Azuma, Atsushi Sakashita, Seiji Shioda & Kouhei Matsuda. (2010) Effect of Intraperitoneal Injection of Curcumin on Food Intake in a Goldfish Model. Journal of Molecular Neuroscience 45:2, pages 172-176.
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Mohammad B. Hossain, Ankit Patras, Catherine Barry-Ryan, Ana B. Martin-Diana & Nigel P. Brunton. (2011) Application of principal component and hierarchical cluster analysis to classify different spices based on in vitro antioxidant activity and individual polyphenolic antioxidant compounds. Journal of Functional Foods 3:3, pages 179-189.
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Kee-Hong KimYeonhwa Park. (2011) Food Components with Anti-Obesity Effect. Annual Review of Food Science and Technology 2:1, pages 237-257.
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Malenahalli C. ShubhaRaghunatha R.L. ReddyKrishnapura Srinivasan. (2011) Antilithogenic influence of dietary capsaicin and curcumin during experimental induction of cholesterol gallstone in mice. Applied Physiology, Nutrition, and Metabolism 36:2, pages 201-209.
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Krishnapura Srinivasan. 2010. Functional Foods of the East. Functional Foods of the East 51 84 .
Satyakumar Vidyashankar, Kari Sambaiah & Krishnapura Srinivasan. (2010) Regression of preestablished cholesterol gallstones by dietary garlic and onion in experimental mice. Metabolism 59:10, pages 1402-1412.
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H. G. Vidyavati, H. Manjunatha, J. Hemavathy & K. Srinivasan. (2010) Hypolipidemic and antioxidant efficacy of dehydrated onion in experimental rats. Journal of Food Science and Technology 47:1, pages 55-60.
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R.L.R. ReddyK. Srinivasan. (2009) Fenugreek seeds reduce atherogenic diet-induced cholesterol gallstone formation in experimental mice. Canadian Journal of Physiology and Pharmacology 87:11, pages 933-943.
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R.L.R. ReddyK. Srinivasan. (2009) Dietary fenugreek seed regresses preestablished cholesterol gallstones in mice. Canadian Journal of Physiology and Pharmacology 87:9, pages 684-693.
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Satyakumar Vidyashankar, Kari Sambaiah & Krishnapura Srinivasan. (2008) Dietary garlic and onion reduce the incidence of atherogenic diet-induced cholesterol gallstones in experimental mice. British Journal of Nutrition 101:11, pages 1621-1629.
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Magdolna Pákáski, Marietta Hugyecz, Péter Sántha, Gábor Jancsó, Annamária Bjelik, Ágnes Domokos, Zoltán Janka & János Kálmán. (2009) Capsaicin promotes the amyloidogenic route of brain amyloid precursor protein processing. Neurochemistry International 54:7, pages 426-430.
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Lilian Regina Barros Mariutti & Neura Bragagnolo. (2009) A oxidação lipídica em carne de frango e o impacto da adição de sálvia (Salvia officinalis, L.) e de alho (Allium sativum, L.) como antioxidantes naturais. Revista do Instituto Adolfo Lutz 68:1, pages 1-11.
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K. Srinivasan, K. Platel & M. V. L. Rao. (2008) Hypotriglyceridemic effect of dietary vanillin in experimental rats. European Food Research and Technology 228:1, pages 103-108.
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M. R. Srinivasan, N. Chandrasekhara & K. Srinivasan. (2008) Cholesterol lowering activity of mango ginger (Curcuma amada Roxb.) in induced hypercholesterolemic rats. European Food Research and Technology 227:4, pages 1159-1163.
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H. Manjunatha & K. Srinivasan. (2007) Hypolipidemic and Antioxidant Effects of Dietary Curcumin and Capsaicin in Induced Hypercholesterolemic Rats. Lipids 42:12, pages 1133-1142.
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D. Suresh & K. Srinivasan. (2007) Studies on the in vitro absorption of spice principles – Curcumin, capsaicin and piperine in rat intestines. Food and Chemical Toxicology 45:8, pages 1437-1442.
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H. ManjunathaK. Srinivasan. (2007) Hypolipidemic and antioxidant effects of curcumin and capsaicin in high-fat-fed rats. Canadian Journal of Physiology and Pharmacology 85:6, pages 588-596.
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D. SureshK. Srinivasan. (2006) Influence of curcumin, capsaicin, and piperine on the rat liver drug-metabolizing enzyme system in vivo and in vitro. Canadian Journal of Physiology and Pharmacology 84:12, pages 1259-1265.
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Rayavara K. Kempaiah & Krishnapura Srinivasan. (2007) Influence of dietary spices on the fluidity of erythrocytes in hypercholesterolaemic rats. British Journal of Nutrition 93:1, pages 81-91.
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Krishnapura Srinivasan. (2005) Spices as influencers of body metabolism: an overview of three decades of research. Food Research International 38:1, pages 77-86.
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