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Research Article

Immunomodulatory and Antitumor Actions of Medicinal Plant Tinospora cordifolia Are Mediated Through Activation of Tumor‐Associated Macrophages

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Pages 145-162 | Published online: 03 Nov 2004

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Vinod Prabhu & C. Guruvayoorappan. (2010) Nitric oxide: pros and cons in tumor progression. Immunopharmacology and Immunotoxicology 32:3, pages 387-392.
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Nisha Singh, Sukh Mahendra Singh & Pratima Shrivastava. (2005) Effect of Tinospora Cordifolia on the Antitumor Activity of Tumor-Associated Macrophages–Derived Dendritic Cells. Immunopharmacology and Immunotoxicology 27:1, pages 1-14.
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Feng Z. Jin, Mu L. Lian, Xia Wang & Qun Wei. (2005) Studies of the Anticancer Effect of Calcineurin B. Immunopharmacology and Immunotoxicology 27:2, pages 199-210.
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Pratima Shrivastava, Sukh Mahendra Singh & Nisha Singh. (2005) Antitumor Activation of Peritoneal Macrophages by Thymosin Alpha-1. Cancer Investigation 23:4, pages 316-322.
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Nisha Singh, Sukh Mahendra Singh, Prakash & Gajendra Singh. (2005) Restoration of Thymic Homeostasis in a Tumor-Bearing Host by in Vivo Administration of Medicinal Herb Tinospora Cordifolia. Immunopharmacology and Immunotoxicology 27:4, pages 585-599.
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Articles from other publishers (30)

Atiqul Islam, Harjeet Singh & Alok Sharma. (2023) Impact of Regional Quality Assessment of Tinospora cordifolia: A Scientific Perspective for Exploration of Harvest Strategy as a Quality Marker. Agricultural Research 12:3, pages 277-284.
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Mangathayaru Kalachaveedu, Reshma Senthil, Sowndarya Azhagiyamanavalan, Ramnarayanan Ravi, Harikrishnan Meenakshisundaram & Arunasalam Dharmarajan. (2023) Traditional medicine herbs as natural product matrices in cancer chemoprevention: A trans pharmacological perspective (scoping review). Phytotherapy Research 37:4, pages 1539-1573.
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Rong Jie Zhao, Dae Geon Lee, Chan Sik Park, Chae Ha Yang, Hee Young Kim, Mi Young Lee, Chang-Hyun Song, Il Je Cho, Sang Chan Kim, Sae Kwang Ku & Bong Hyo Lee. (2022) Acupuncture Inhibits Morphine Induced-Immune Suppress via Antioxidant System. Evidence-Based Complementary and Alternative Medicine 2022, pages 1-38.
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Ankita Gautam. 2022. Research Anthology on Recent Advancements in Ethnopharmacology and Nutraceuticals. Research Anthology on Recent Advancements in Ethnopharmacology and Nutraceuticals 101 118 .
Karuppusamy Arunachalam, Xuefei Yang & Thae Thae San. (2022) Tinospora cordifolia (Willd.) Miers: Protection mechanisms and strategies against oxidative stress-related diseases. Journal of Ethnopharmacology 283, pages 114540.
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Snehal Suryavanshi, Kavita Shinde, Prerna Raina & Ruchika Kaul-Ghanekar. (2020) Tumor retardation and immunomodulatory potential of polyherbal formulation HC9 in mouse melanoma model. Pharmacognosy Magazine 16:68, pages 181.
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Ankita Gautam. 2020. Advanced Pharmacological Uses of Medicinal Plants and Natural Products. Advanced Pharmacological Uses of Medicinal Plants and Natural Products 316 337 .
Ambarish Mukherjee & Mousumi Banerjee. 2020. Herbal Medicine in India. Herbal Medicine in India 23 39 .
Shahid AkbarShahid Akbar. 2020. Handbook of 200 Medicinal Plants. Handbook of 200 Medicinal Plants 1811 1824 .
Arathi Nair, Debprasad Chattopadhyay & Bhaskar Saha. 2019. New Look to Phytomedicine. New Look to Phytomedicine 435 499 .
Kshirod K Ratha & Sudhanshu K Meher. (2018) An Enumeration and Review of Medicinal Plants Mentioned in Bhela Samhita . Journal of Drug Research in Ayurvedic Sciences 3:1, pages 53-62.
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Lalrinpuia Kawlni, Sachchidanand Upadhayay & Koyel Mukherjee. (2018) Comprehensive Pharmacology Review of Guduchi [ Tinospora cordifolia (Willd.) Miers] . Journal of Drug Research in Ayurvedic Sciences 3:1, pages 48-52.
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Picheswara Rao Polu, Udupa Nayanbhirama, Saleemulla Khan & Rajlexmi Maheswari. (2017) Assessment of free radical scavenging and anti-proliferative activities of Tinospora cordifolia Miers (Willd). BMC Complementary and Alternative Medicine 17:1.
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Md. Areeful Haque, Ibrahim Jantan & Syed Nasir Abbas Bukhari. (2017) Tinospora species: An overview of their modulating effects on the immune system. Journal of Ethnopharmacology 207, pages 67-85.
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Deepika Singh & Prabir K Chaudhuri. (2017) Chemistry and Pharmacology of Tinospora cordifolia . Natural Product Communications 12:2, pages 1934578X1701200.
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Appian Subramoniam. 2016. Plants with Anti-Diabetes Mellitus Properties. Plants with Anti-Diabetes Mellitus Properties 441 567 .
Vikas Bajpai, Awantika Singh, Preeti Chandra, M. P. S. Negi, Nikhil Kumar & Brijesh Kumar. (2016) Analysis of phytochemical variations in dioecious Tinospora cordifolia stems using HPLC/QTOF MS/MS and UPLC/QqQ LIT -MS/MS . Phytochemical Analysis 27:2, pages 92-99.
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M. Tiwari, U.N. Dwivedi & P. Kakkar. (2014) Tinospora cordifolia extract modulates COX-2, iNOS, ICAM-1, pro-inflammatory cytokines and redox status in murine model of asthma. Journal of Ethnopharmacology 153:2, pages 326-337.
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Heena Sachdeva, Rakesh Sehgal & Sukhbir Kaur. (2014) Tinospora cordifolia as a protective and immunomodulatory agent in combination with cisplatin against murine visceral leishmaniasis. Experimental Parasitology 137, pages 53-65.
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Ivan Aranha, Fatima Clement & Yeldur P. Venkatesh. (2012) Immunostimulatory properties of the major protein from the stem of the Ayurvedic medicinal herb, guduchi (Tinospora cordifolia). Journal of Ethnopharmacology 139:2, pages 366-372.
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S.K. Mallick, S. Maiti, S.K. Bhutia & T.K. Maiti. (2010) Antitumor properties of a heteroglucan isolated from Astraeus hygrometricus on Dalton’s lymphoma bearing mouse. Food and Chemical Toxicology 48:8-9, pages 2115-2121.
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Sujit K. Bhutia, Sanjaya K. Mallick & Tapas K. Maiti. (2009) In vitro immunostimulatory properties of Abrus lectins derived peptides in tumor bearing mice. Phytomedicine 16:8, pages 776-782.
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Anil Mittal & Rana P. Singh. 2009. Herbal Drugs: Ethnomedicine to Modern Medicine. Herbal Drugs: Ethnomedicine to Modern Medicine 195 206 .
Vivekanand Gupta & Sukh Mahendra Singh. (2008) Sex dimorphism in antitumor response of chemotherapeutic drug cisplatin in a murine host-bearing a T-cell lymphoma. Anti-Cancer Drugs 19:6, pages 583-592.
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T. S. Panchabhai, U. P. Kulkarni & N. N. Rege. (2007) Validation of therapeutic claims of Tinospora cordifolia : a review . Phytotherapy Research 22:4, pages 425-441.
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Sanjaya Kumar Mallick, Vivekanand Gupta, Mahendra Pal Singh, Naveen Kumar Vishvakarma, Nisha Singh & Sukh Mahendra Singh. (2008) Effect of Neem (Azadirachta indica) oil on the progressive growth of a spontaneous T cell lymphoma. Oriental Pharmacy and Experimental Medicine 7:5, pages 459-465.
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G. Thippeswamy & B.P. Salimath. (2007) Induction of caspase-3 activated DNase mediated apoptosis by hexane fraction of Tinospora cordifolia in EAT cells. Environmental Toxicology and Pharmacology 23:2, pages 212-220.
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Amritpal Singh. 2006. Compendia of World's Medicinal Flora. Compendia of World's Medicinal Flora 270 314 .
Sukh Mahendra Singh, Nisha Singh & Pratima Shrivastava. (2006) Effect of alcoholic extract of Ayurvedic herb Tinospora cordifolia on the proliferation and myeloid differentiation of bone marrow precursor cells in a tumor-bearing host. Fitoterapia 77:1, pages 1-11.
Crossref
Mahendra Pal Singh, Ambak Kumar Rai & Sukh Mahendra Singh. (2005) Gender dimorphism in the progressive in vivo growth of a T cell lymphoma: involvement of cytokines and gonadal hormones. Journal of Reproductive Immunology 65:1, pages 17-32.
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