Advanced search
Publication Cover
Journal of Liquid Chromatography & Related Technologies Volume 24, 2001 - Issue 11-12
Submit an article Journal homepage
151
Views
21
CrossRef citations to date
0
Altmetric
Original Articles

SEPARATION OF CRUDE PLANT EXTRACTS WITH HIGH SPEED CCC FOR PRIMARY SCREENING IN DRUG DISCOVERY

Jean A. Armbruster Department of Natural Products Drug Discovery, Merck Research Laboratories, R80Y-355, P. O. Box 2000, Rahway, NJ, 07065, U.S.A.
,
Robert P. Borris Department of Natural Products Drug Discovery, Merck Research Laboratories, R80Y-355, P. O. Box 2000, Rahway, NJ, 07065, U.S.A.
,
Quirico Jimenez Instituto Nacional de Biodiversidad (INBio), Apdo. 22-3100, Santo Domingo, Heredia, Costa Rica
,
Nelson Zamora Instituto Nacional de Biodiversidad (INBio), Apdo. 22-3100, Santo Domingo, Heredia, Costa Rica
,
Giselle Tamayo-Castillo Instituto Nacional de Biodiversidad (INBio), Apdo. 22-3100, Santo Domingo, Heredia, Costa Rica
&
Guy H. Harris Department of Natural Products Drug Discovery, Merck Research Laboratories, R80Y-355, P. O. Box 2000, Rahway, NJ, 07065, U.S.A.Correspondence[email protected]
Pages 1827-1840 | Received 21 Sep 2000, Accepted 10 Dec 2000, Published online: 06 Feb 2007

Citations (21)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Qizhen Du. (2011) THE FEATURES OF RAPID COUNTER-CURRENT CHROMATOGRAPHIC SEPARATIONS. Journal of Liquid Chromatography & Related Technologies 34:18, pages 2074-2084.
Read now
Taichi Inui, Ryan Case, Edward Chou, D. Doel Soejarto, HarryH. S. Fong, Scott G. Franzblau, David C. Smith & Guido F. Pauli. (2005) CCC in the Phytochemical Analysis of Anti‐Tuberculosis Ethnobotanicals. Journal of Liquid Chromatography & Related Technologies 28:12-13, pages 2017-2028.
Read now

Articles from other publishers (19)

Roberto G. S. Berlinck, Camila M. Crnkovic, Juliana R. Gubiani, Darlon I. Bernardi, Laura P. Ióca & Jairo I. Quintana-Bulla. (2022) The isolation of water-soluble natural products – challenges, strategies and perspectives. Natural Product Reports 39:3, pages 596-669.
Crossref
Xiao Sun, Dong Pei, Wen‐Da Duan, Jian‐Fei Liu, Duo‐Long Di & Xin‐Yi Huang. (2020) Full use of the liquid nature of the stationary phase: The development of elution‐extrusion counter current chromatography. Journal of Separation Science 43:17, pages 3573-3584.
Crossref
Walter Vetter, Marco Müller, Michael Englert & Simon Hammann. 2020. Liquid-Phase Extraction. Liquid-Phase Extraction 289 325 .
Ngoc Pham, Stephen Toms, David Camp & Ronald Quinn. 2015. Marine Biomedicine. Marine Biomedicine 91 104 .
Karine Faure, Nazim Mekaoui & Alain Berthod. 2014. Green Chromatographic Techniques. Green Chromatographic Techniques 1 18 .
Dingfang Wu, Xiaoji Cao & Shihua Wu. (2012) Overlapping elution–extrusion counter-current chromatography: A novel method for efficient purification of natural cytotoxic andrographolides from Andrographis paniculata. Journal of Chromatography A 1223, pages 53-63.
Crossref
Tim S. Bugni*Mary Kay Harper, Malcolm W.B. McCulloch & Emily L. Whitson. 2009. Natural Product Chemistry for Drug Discovery. Natural Product Chemistry for Drug Discovery 272 298 .
Vanessa Gisele Pasqualotto Severino, Cristiane de Melo Cazal, Moacir Rossi Forim, Maria Fátima das Graças Fernandes da Silva, Edson Rodrigues-Filho, João Batista Fernandes & Paulo Cezar Vieira. (2009) Isolation of secondary metabolites from Hortia oreadica (Rutaceae) leaves through high-speed counter-current chromatography. Journal of Chromatography A 1216:19, pages 4275-4281.
Crossref
Christopher Napolitano, Michael Wismer, Elio Furlano, Guy Harris, Brian Uhrig, Kevin Blake, Gary Kath & Claude Dufresne. (2009) An In-House Built Semiautomated Countercurrent Chromatography Workstation. JALA: Journal of the Association for Laboratory Automation 14:1, pages 27-35.
Crossref
Guido F. Pauli, Samuel M. Pro & J. Brent Friesen. (2008) Countercurrent Separation of Natural Products. Journal of Natural Products 71:8, pages 1489-1508.
Crossref
Ryan J. Case, Yuehong Wang, Scott G. Franzblau, D. Doel Soejarto, Lohi Matainaho, Pius Piskaut & Guido F. Pauli. (2007) Advanced applications of counter-current chromatography in the isolation of anti-tuberculosis constituents from Dracaena angustifolia. Journal of Chromatography A 1151:1-2, pages 169-174.
Crossref
Carole Jubert & George Bailey. (2007) Isolation of chlorophylls a and b from spinach by counter-current chromatography. Journal of Chromatography A 1140:1-2, pages 95-100.
Crossref
Wilfried Rémus-Borel, Nancy Shallow, David J. McNally, Caroline Labbé & Richard R. Bélanger. (2006) High-speed counter-current chromatography for the study of defense metabolites in wheat. Journal of Chromatography A 1121:2, pages 200-208.
Crossref
Mark S. Butler. (2004) The Role of Natural Product Chemistry in Drug Discovery. Journal of Natural Products 67:12, pages 2141-2153.
Crossref
Antony D. Buss & Mark S. Butler. (2004) A new model for utilising chemical diversity from natural sources. Drug Development Research 62:4, pages 362-370.
Crossref
Alain Berthod, Maria Jose Ruiz-Angel & Samuel Carda-Broch. (2003) Elution−Extrusion Countercurrent Chromatography. Use of the Liquid Nature of the Stationary Phase To Extend the Hydrophobicity Window. Analytical Chemistry 75:21, pages 5886-5894.
Crossref
Jed W Fahey, Kristina L Wade, Katherine K Stephenson & F.Edward Chou. (2003) Separation and purification of glucosinolates from crude plant homogenates by high-speed counter-current chromatography. Journal of Chromatography A 996:1-2, pages 85-93.
Crossref
Guy H. Harris. 2002. Countercurrent Chromatography - The Support-Free Liquid Stationary Phase. Countercurrent Chromatography - The Support-Free Liquid Stationary Phase 301 330 .
. (2002) Current Awareness in phytochemical analysis. Phytochemical Analysis 13:1, pages 55-62.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.