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Journal of Liquid Chromatography & Related Technologies Volume 26, 2003 - Issue 8
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Original Articles

A Rapid and Sensitive HPLC Method for the Determination of Venlafaxine and O‐Desmethylvenlafaxine in Human Plasma with UV Detection

B. B. Raut Wockhardt Research Centre, Aurangabad, Maharashtra State, India; Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, Maharashtra State, 431004, India
,
B. L. Kolte Wockhardt Research Centre, Aurangabad, Maharashtra State, India; Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, Maharashtra State, 431004, India
,
A. A. Deo Wockhardt Research Centre, Aurangabad, Maharashtra State, India
,
M. A. Bagool Wockhardt Research Centre, Aurangabad, Maharashtra State, India
&
D. B. Shinde Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, Maharashtra State, 431004, IndiaCorrespondence[email protected]
Pages 1297-1313 | Received 12 Nov 2002, Accepted 20 Dec 2002, Published online: 24 Jun 2011

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D. Chandrapal Reddy, A.T. Bapuji, V. Suryanarayana Rao, V. Himabindu & S. Ravinder. (2013) HIGH THROUGHPUT AND SENSITIVE LC-MS/MS METHOD FOR THE ESTIMATION OF VENLAFAXINE AND ITS ACTIVE METABOLITE O-DESMETHYL VENLAFAXINE IN HUMAN PLASMA AND ITS APPLICATION TO A PHARMACOKINETIC STUDY. Journal of Liquid Chromatography & Related Technologies 36:7, pages 897-913.
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Cafer Saka & Ömer Şahin. (2013) Determination of Serotonin-Norepinephrine Reuptake Inhibitor Antidepressants in Pharmaceuticals and Biological Material. Critical Reviews in Analytical Chemistry 43:1, pages 2-34.
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Sarah M. R. Wille, Sarah G. Cooreman, Hugo M. Neels & Willy E. E. Lambert. (2008) Relevant Issues in the Monitoring and the Toxicology of Antidepressants. Critical Reviews in Clinical Laboratory Sciences 45:1, pages 25-89.
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Articles from other publishers (12)

K. Bhavya SriMaimuna BegumNarmada NarmadaMogili Sumakanth. (2023) Development and Validation of a RP-HPLC Method for the determination of Venlafaxine hydrochloride in bulk and Pharmaceutical Dosage Forms. Research Journal of Pharmacy and Technology, pages 524-528.
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Gui-Feng Tong, Nan Qin & Li-Wei Sun. (2017) Development and evaluation of Desvenlafaxine loaded PLGA-chitosan nanoparticles for brain delivery. Saudi Pharmaceutical Journal 25:6, pages 844-851.
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Paulo Magalhães, Gilberto Alves, Márcio Rodrigues, Adrián LLerena & Amílcar Falcão. (2014) First MEPS/HPLC assay for the simultaneous determination of venlafaxine and O -desmethylvenlafaxine in human plasma . Bioanalysis 6:22, pages 3025-3038.
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Karri Visweswara Rao, Kesareddy Padmaja Reddy & Yelavarthi Ravindra Kumar. (2014) Stability Indicating LC Method for Rapid Determination of Related Substances of O-Desmethyl Venlafaxine in Active Pharmaceutical Ingredients and Pharmaceutical Formulations. Journal of Chromatographic Science 52:10, pages 1247-1254.
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Sunil Kumar Dubey, R.N. Saha, Hemanth Jangala & S. Pasha. (2013) Rapid sensitive validated UPLC–MS method for determination of venlafaxine and its metabolite in rat plasma: Application to pharmacokinetic study. Journal of Pharmaceutical Analysis 3:6, pages 466-471.
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Bokka Ramesh, Panguluri Narayana, Ala Reddy & Potturi Devi. (2011) Stability-indicating HPTLC method for analysis of venlafaxine hydrochloride, and use of the method to study degradation kinetics. Journal of Planar Chromatography ? Modern TLC 24:2, pages 160-165.
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Sheikh Shahnawaz, Zaki Siddiqui & Quaisul Hoda. (2010) Sensitive Spectrofluorimetric Method of Analysis for Venlafaxine in Spiked Rat Plasma and Formulations. Journal of Fluorescence 20:4, pages 821-825.
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Donata Favretto, Giulia Stocchero, Susanna Vogliardi, Giampietro Frison, Daniele Trevisanuto, Franca Castagna & Santo Davide Ferrara. (2010) Neonatal Hair Analysis by Liquid Chromatography-High-Resolution Mass Spectrometry to Reveal Gestational Exposure to Venlafaxine. Therapeutic Drug Monitoring 32:1, pages 30-39.
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Gaurang R. Shah, Bharat T. Thaker, Kiran R. Surati & Minu H. Parabia. (2009) Simultaneous Determination of Venlafaxine and Its Main Active Metabolite O-Desmethyl Venlafaxine in Rat Plasma by LC-MS/MS. Analytical Sciences 25:10, pages 1207-1210.
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Victoria SamanidouParaskevi Kourti. (2009) Modern bioanalytical methods for the rapid detection of antidepressants: SNRIs and SSRIs in human biological samples. Bioanalysis 1:2, pages 451-488.
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Roberto Mandrioli, Laura Mercolini, Roberta Cesta, Salvatore Fanali, Mario Amore & Maria Augusta Raggi. (2007) Analysis of the second generation antidepressant venlafaxine and its main active metabolite O-desmethylvenlafaxine in human plasma by HPLC with spectrofluorimetric detection. Journal of Chromatography B 856:1-2, pages 88-94.
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Paraskevas D. Tzanavaras, Aspasia Verdoukas & Demetrius G. Themelis. (2005) Development and Validation of a Flow-Injection Assay for Dissolution Studies of the Anti-depressant Drug Venlafaxine. Analytical Sciences 21:12, pages 1515-1518.
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