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Journal of Liquid Chromatography & Related Technologies Volume 26, 2003 - Issue 9-10
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Original Articles

Separation of Dammarane‐Saponins from Notoginseng, Root of Panax notoginseng (Burk.) F. H. Chen, by HSCCC Coupled with Evaporative Light Scattering Detector

Xue‐Li Cao Beijing Institute of New Technology Application, Xizhimen South Street, No. 16, Beijing, 100035, P.R. China
,
Yu Tian Beijing Institute of New Technology Application, Xizhimen South Street, No. 16, Beijing, 100035, P.R. China
,
Tian‐You Zhang Beijing Institute of New Technology Application, Xizhimen South Street, No. 16, Beijing, 100035, P.R. ChinaCorrespondence[email protected]
,
Qing‐Hui Liu Beijing Institute of New Technology Application, Xizhimen South Street, No. 16, Beijing, 100035, P.R. China
,
Li‐Jun Jia Beijing Institute of New Technology Application, Xizhimen South Street, No. 16, Beijing, 100035, P.R. China
&
Yoichiro Ito Biophysical Chemical Laboratory, Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA
Pages 1579-1591 | Received 21 Apr 2002, Accepted 07 Oct 2002, Published online: 06 Feb 2007

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Chun Wang, Zhimao Chao, Wen Sun, Xiaoyi Wu & Yoichiro Ito. (2014) ISOLATION OF FIVE GLYCOSIDES FROM THE BARKS OF ILEX ROTUNDA BY HIGH-SPEED COUNTER-CURRENT CHROMATOGRAPHY. Journal of Liquid Chromatography & Related Technologies 37:16, pages 2363-2376.
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Jing Wang, Jing Yu, Li Li, Chun-ming Liu, Yuchi Zhang & Qiang Wang. (2013) ISOLATION OF HIGH PURITY GINSENOSIDES FROM PLANT EXTRACT OF PANAX GINSENG BY HIGH PERFORMANCE CENTRIFUGAL PARTITION CHROMATOGRAPHY COUPLED WITH EVAPORATIVE LIGHT SCATTERING DETECTION. Journal of Liquid Chromatography & Related Technologies 36:5, pages 583-590.
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Fengqin Chen, Jianguang Luo & Lingyi Kong. (2012) FAST ISOLATION OF GINSENOSIDES Re AND Rg1 FROM THE ROOTS OF PANAX GINSENG BY HSCCC-ELSD COMBINED WITH MCI GEL CC GUIDED BY HPLC-MS. Journal of Liquid Chromatography & Related Technologies 35:7, pages 912-923.
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Qiang Ma, Jianguang Luo & Lingyi Kong. (2011) PREPARATIVE ISOLATION OF STEROIDAL SAPONINS FROM GARLIC (ALLIUM SATIVUM L.) USING HIGH-SPEED COUNTER-CURRENT CHROMATOGRAPHY COUPLED WITH EVAPORATIVE LIGHT SCATTERING DETECTION. Journal of Liquid Chromatography & Related Technologies 34:17, pages 1997-2007.
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Lianhong Yin, Yingnan Li, Binan Lu, Yujie Jia & Jinyong Peng. (2010) Trends in Counter-Current Chromatography: Applications to Natural Products Purification. Separation & Purification Reviews 39:1-2, pages 33-62.
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Articles from other publishers (36)

Shuai Li, Han Zhang, Jie Huai, Huixia Wang, Shengfu Li, Linwu Zhuang & Junjie Zhang. (2023) An online preparative high-performance liquid chromatography system with enrichment and purification modes for the efficient and systematic separation of Panax notoginseng saponins. Journal of Chromatography A, pages 464378.
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Hengmian Sun, Li‐Juan Ma, Jian‐Bo Wan & Shengqiang Tong. (2021) Preparative separation of gypenoside XVII, ginsenoside Rd2, and notoginsenosides Fe and Fd from Panax notoginseng leaves by countercurrent chromatography and orthogonality evaluation for their separation . Journal of Separation Science 44:15, pages 2996-3003.
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Yuangui Yang, Zhengcai Ju, Yingbo Yang, Yanhai Zhang, Li Yang & Zhengtao Wang. (2021) Phytochemical analysis of Panax species: a review. Journal of Ginseng Research 45:1, pages 1-21.
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Fabiana de Souza Figueiredo, Rita Celano, Danila de Sousa Silva, Fernanda das Neves Costa, Peter Hewitson, Svetlana Ignatova, Anna Lisa Piccinelli, Luca Rastrelli, Suzana Guimarães Leitão & Gilda Guimarães Leitão. (2017) Countercurrent chromatography separation of saponins by skeleton type from Ampelozizyphus amazonicus for off-line ultra-high-performance liquid chromatography/high resolution accurate mass spectrometry analysis and characterisation. Journal of Chromatography A 1481, pages 92-100.
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Hua Song, Jianhong Lin, Xuan Zhu & Qing Chen. (2016) Developments in high-speed countercurrent chromatography and its applications in the separation of terpenoids and saponins. Journal of Separation Science 39:8, pages 1574-1591.
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Sainan Li, Ying Tang, Chunming Liu & Yuchi Zhang. (2015) Development of a method to screen and isolate potential α-glucosidase inhibitors from Panax japonicus C.A. Meyer by ultrafiltration, liquid chromatography, and counter-current chromatography . Journal of Separation Science 38:12, pages 2014-2023.
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Bo Li, Li Li, Anqi Zhao, Binhua Han, Yajun Fan, Chunming Liu & Jianjun Liu. (2015) Preparative separation of isoflavones in plant extract of Pueraria lobata by high performance counter-current chromatography. Analytical Methods 7:4, pages 1321-1327.
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Mengshun Liu, Ling Tao, Siu Leung Chau, Rong Wu, Hong Zhang, Yifu Yang, Dajian Yang, Zhaoxiang Bian, Aiping Lu, Quanbin Han & Hongxi Xu. (2014) Folding fan mode counter-current chromatography offers fast blind screening for drug discovery. Case study: Finding anti-enterovirus 71 agents from Anemarrhena asphodeloides. Journal of Chromatography A 1368, pages 116-124.
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Krystyna Skalicka-Woźniak & Ian Garrard. (2014) Counter-current chromatography for the separation of terpenoids: a comprehensive review with respect to the solvent systems employed. Phytochemistry Reviews 13:2, pages 547-572.
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Patrick Chaimbault. 2014. Recent Advances in Redox Active Plant and Microbial Products. Recent Advances in Redox Active Plant and Microbial Products 31 94 .
Yuchi Zhang, Liping Guo, Chunming Liu, Yanjuan Qi, Dongping Li & Sainan Li. (2013) Combination of pressurized liquid extraction with countercurrent chromatography for systematical isolation of ginsenosides from Panax ginseng. Separation and Purification Technology 116, pages 240-247.
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Guoan Luo, Yiming Wang, Qionglin Liang & Qingfei Liu. 2012. Systems Biology for Traditional Chinese Medicine. Systems Biology for Traditional Chinese Medicine 66 130 .
Shun Yao, Yu Cao, Chun-mei Jia, Yan Wang & Hang Song. (2012) Developments of instruments and methods related with high-speed countercurrent chromatography and their applications in research of natural medicines. Open Chemistry 10:3, pages 417-432.
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Omer Shehzad, Salman Khan, In Jin Ha, Youmie Park & Yeong Shik Kim. (2012) Rational development of a selection model for solvent gradients in single‐step separation of ginsenosides from P anax ginseng using high‐speed counter‐current chromatography . Journal of Separation Science 35:12, pages 1462-1469.
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In J. Ha, Minseok Kang, Yun C. Na, Youmie Park & Yeong S. Kim. (2011) Preparative separation of minor saponins from Platycodi Radix by high‐speed counter‐current chromatography . Journal of Separation Science 34:19, pages 2559-2565.
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Dae-Young Lee, Jin-Gyeong Cho, Myun-Ho Bang, Min-Woo Han, Min-Ho Lee, Deok-Chun Yang & Nam-In Baek. (2011) Discrimination of Korean ginseng (Panax ginseng) roots using rapid resolution LC-QTOF/MS combined by multivariate statistical analysis. Food Science and Biotechnology 20:4, pages 1119-1124.
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Jing Wang, Chun‐ming Liu, Li Li & He‐long Bai. (2011) Isolation of four high‐purity dammarane saponins from extract of Panax notoginseng by centrifugal partition chromatography coupled with evaporative light scattering detection in one operation . Phytochemical Analysis 22:3, pages 263-267.
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Omer Shehzad, In Jin Ha, Youmie Park, Young Wan Ha & Yeong Shik Kim. (2011) Development of a rapid and convenient method to separate eight ginsenosides from Panax ginseng by high‐speed counter‐current chromatography coupled with evaporative light scattering detection . Journal of Separation Science 34:10, pages 1116-1122.
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Dae-Young Lee, Jin-Gyeong Cho, Min-Kyung Lee, Jae-Woong Lee, Youn-Hyung Lee, Deok-Chun Yang & Nam-In Baek. (2011) Discrimination of Panax ginseng Roots Cultivated in Different Areas in Korea Using HPLC-ELSD and Principal Component Analysis. Journal of Ginseng Research 35:1, pages 31-38.
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Lian-Wen Qi, Chong-Zhi Wang & Chun-Su Yuan. (2011) Isolation and analysis of ginseng: advances and challenges. Natural Product Reports 28:3, pages 467.
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Yijun Cheng, Qionglin Liang, Ping Hu, Yiming Wang, Frank Wu Jun & Guoan Luo. (2010) Combination of normal-phase medium-pressure liquid chromatography and high-performance counter-current chromatography for preparation of ginsenoside-Ro from panax ginseng with high recovery and efficiency. Separation and Purification Technology 73:3, pages 397-402.
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In Jin Ha, Young Wan Ha, Minseok Kang, Jongsung Lee, Deokhoon Park & Yeong Shik Kim. (2010) Enzymatic transformation of platycosides and one-step separation of platycodin D by high-speed countercurrent chromatography. Journal of Separation Science 33:13, pages 1916-1922.
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Jin-Gyeong Cho, Min-Kyung Lee, Jae-Woong Lee, Hee-Jung Park, Dae-Young Lee, Youn-Hyung Lee, Deok-Chun Yang & Nam-In Baek. (2010) Physicochemical Characterization and NMR Assignments of Ginsenosides Rb 1 , Rb 2 , R c , and Rd Isolated from Panax ginseng . Journal of Ginseng Research 34:2, pages 113-121.
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Xiaocheng Qi, Svetlana Ignatova, Guoan Luo, Qionglin Liang, Frank Wu Jun, Yiming Wang & Ian Sutherland. (2010) Preparative isolation and purification of ginsenosides Rf, Re, Rd and Rb1 from the roots of Panax ginseng with a salt/containing solvent system and flow step-gradient by high performance counter-current chromatography coupled with an evaporative light scattering detector. Journal of Chromatography A 1217:13, pages 1995-2001.
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A. Berthod, M.J. Ruiz-Ángel & S. Carda-Broch. (2009) Countercurrent chromatography: People and applications. Journal of Chromatography A 1216:19, pages 4206-4217.
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Shun YAO. (2009) Methodology Research of High-speed Counter-current Chromatography in Separation of Natural Products. Chinese Journal of Natural Medicines 6:1, pages 13-19.
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Ian A. Sutherland & Derek Fisher. (2009) Role of counter-current chromatography in the modernisation of Chinese herbal medicines. Journal of Chromatography A 1216:4, pages 740-753.
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Tingting Wang, Xinhang Jiang, Lu Yang & Shihua Wu. (2008) pH-gradient counter-current chromatography isolation of natural antioxidant chlorogenic acid from Lonicera japonica Thumb. using an upright coil planet centrifuge with three multi-layer coils connected in series. Journal of Chromatography A 1180:1-2, pages 53-58.
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Young Wan Ha, Soon Sung Lim, In Jin Ha, Yun-Cheol Na, Jung-Ju Seo, Heungsop Shin, Sung Ho Son & Yeong Shik Kim. (2007) Preparative isolation of four ginsenosides from Korean red ginseng (steam-treated Panax ginseng C. A. Meyer), by high-speed counter-current chromatography coupled with evaporative light scattering detection. Journal of Chromatography A 1151:1-2, pages 37-44.
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Shun Yao, Renming Liu, Xuefeng Huang & Lingyi Kong. (2007) Preparative isolation and purification of chemical constituents from the root of Adenophora tetraphlla by high-speed counter-current chromatography with evaporative light scattering detection. Journal of Chromatography A 1139:2, pages 254-262.
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Quan Bin Han, Jing Zheng Song, Chun Feng Qiao, Lina Wong & Hong Xi Xu. (2007) Preparative isolation of cyclolanostane‐type saponins from Astragalus membranaceus Bge. var. mongholicus (Bge.) Hsiao by TLC‐MS/MS guided high‐speed counter‐current chromatography . Journal of Separation Science 30:1, pages 135-140.
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A. Marston & K. Hostettmann. (2006) Developments in the application of counter-current chromatography to plant analysis. Journal of Chromatography A 1112:1-2, pages 181-194.
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