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Nucleosides, Nucleotides & Nucleic Acids Volume 20, 2001 - Issue 8
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Original Articles

COMPARISON OF THE ANTIVIRAL ACTIVITY OF HYDROPHOBIC AMINO ACID PHOSPHORAMIDATE MONOESTERS OF 2′, 3′-DIDEOXYADENOSINE (DDA) AND 3′-AZIDO-3′-DEOXYTHYMIDINE (AZT)

Shu-ling Chang Department of Medicinal Chemistry, University of Minnesota, Minneapolis, MN, 55455, U.S.A.
,
George Griesgraber Department of Medicinal Chemistry, University of Minnesota, Minneapolis, MN, 55455, U.S.A.
&
Carston R. Wagner Department of Medicinal Chemistry, University of Minnesota, Minneapolis, MN, 55455, U.S.A.
Pages 1571-1582 | Received 29 Sep 2000, Accepted 07 Feb 2001, Published online: 17 Aug 2006

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Larryn W Peterson & Charles E McKenna. (2009) Prodrug approaches to improving the oral absorption of antiviral nucleotide analogues. Expert Opinion on Drug Delivery 6:4, pages 405-420.
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Daliang Li, Hongli Bao, Qitao Tan, Dongmei Cai & Tianpa You. (2005) Synthesis of Ribavirin Analogues Containing Amino‐Acid Residues. Synthetic Communications 35:8, pages 1017-1026.
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Articles from other publishers (10)

Marta Rachwalak, Joanna Romanowska, Michal Sobkowski & Jacek Stawinski. (2021) Nucleoside Di- and Triphosphates as a New Generation of Anti-HIV Pronucleotides. Chemical and Biological Aspects. Applied Sciences 11:5, pages 2248.
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Uthpala Seneviratne, Susith Wickramaratne, Delshanee Kotandeniya, Arnold S. Groehler, Robert J. Geraghty, Christine Dreis, Suresh S. Pujari & Natalia Y. Tretyakova. (2021) Synthesis and biological evaluation of pyrrolidine-functionalized nucleoside analogs. Medicinal Chemistry Research 30:2, pages 483-499.
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Ugo Pradere, Ethel C. Garnier-Amblard, Steven J. Coats, Franck Amblard & Raymond F. Schinazi. (2014) Synthesis of Nucleoside Phosphate and Phosphonate Prodrugs. Chemical Reviews 114:18, pages 9154-9218.
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Nadege Hamon, Maurizio Quintiliani, Jan Balzarini & Christopher McGuigan. (2013) Synthesis and biological evaluation of prodrugs of 2-fluoro-2-deoxyribose-1-phosphate and 2,2-difluoro-2-deoxyribose-1-phosphate. Bioorganic & Medicinal Chemistry Letters 23:9, pages 2555-2559.
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Cristina Gardelli, Barbara Attenni, Monica Donghi, Malte Meppen, Barbara Pacini, Steven Harper, Annalise Di Marco, Fabrizio Fiore, Claudio Giuliano, Vincenzo Pucci, Ralph Laufer, Nadia Gennari, Isabella Marcucci, Joseph F. Leone, David B. Olsen, Malcolm MacCoss, Michael Rowley & Frank Narjes. (2009) Phosphoramidate Prodrugs of 2′- C -Methylcytidine for Therapy of Hepatitis C Virus Infection . Journal of Medicinal Chemistry 52:17, pages 5394-5407.
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Laëtitia Coudray, Isabelle Abrunhosa-Thomas & Jean-Luc Montchamp. (2007) New access to H-phosphonates via metal-catalyzed phosphorus–oxygen bond formation. Tetrahedron Letters 48:37, pages 6505-6508.
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Tsui-Fen Chou, Janina Baraniak, Renata Kaczmarek, Xin Zhou, Jilin Cheng, Brahma Ghosh & Carston R. Wagner. (2007) Phosphoramidate Pronucleotides:  A Comparison of the Phosphoramidase Substrate Specificity of Human and Escherichia coli Histidine Triad Nucleotide Binding Proteins . Molecular Pharmaceutics 4:2, pages 208-217.
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Jean-François Liotard, Mohamed Mehiri, Audrey Di Giorgio, Nicole Boggetto, Michèle Reboud-Ravaux, Anne-Marie Aubertin, Roger Condom & Nadia Patino. (2016) AZT and AZT-monophosphate Prodrugs Incorporating HIV-protease Substrate Fragment: Synthesis and Evaluation as Specific Drug Delivery Systems. Antiviral Chemistry and Chemotherapy 17:4, pages 193-213.
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Da-Liang Li, Hong-Li Bao, Qi-Tao Tan, Yu-Ping Tan & Tian-Pa You. (2005) Synthesis and Biological Evaluation of a New Category of Purine-Nucleoside Analogues. Chinese Journal of Chemistry 23:12, pages 1659-1664.
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Shu‐ling Chang, George Griesgraber & Carston R. Wagner. (2010) ChemInform Abstract: Comparison of the Antiviral Activity of Hydrophobic Amino Acid Phosphoramidate Monoesters of 2′,3′‐Dideoxyadenosine (ddA) and 3′‐Azido‐3′‐deoxythymidine (AZT).. ChemInform 33:5.
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