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Pharmaceutical Development and Technology Volume 5, 2000 - Issue 1
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Research Article

Waxy Corn Starch: A Potent Cofiller in Pellets Produced by Extrusion–Spheronization

Riitta Junnila Department of Pharmacy, Pharmaceutical Technology Division, University of Helsinki, P.O. Box 56 (Viikinkaari 5)FIN-00014, Finland
,
Päivi Palviainen Department of Pharmacy, Pharmaceutical Technology Division, University of Helsinki, P.O. Box 56 (Viikinkaari 5)FIN-00014, Finland
,
Jyrki Heinämäki Department of Pharmacy, Pharmaceutical Technology Division, University of Helsinki, P.O. Box 56 (Viikinkaari 5)FIN-00014, Finland
,
Päivi Myllärinen
,
Pirkko Forssell
&
Jouko Yliruusi Department of Pharmacy, Pharmaceutical Technology Division, University of Helsinki, P.O. Box 56 (Viikinkaari 5)FIN-00014, Finland
Pages 67-76 | Received 21 Sep 1998, Accepted 12 Jul 1999, Published online: 18 Jan 2000

Citations (12)

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Read on this site (3)

Namdeo R. Jadhav, Atmaram P. Pawar & Anant R. Paradkar. (2011) Preparation and evaluation of talc agglomerates obtained by wet spherical agglomeration as a substrate for coating. Pharmaceutical Development and Technology 16:2, pages 152-161.
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Satishkumar P. Jain, Pirthi Pal Singh & Purnima D. Amin. (2010) Alternative extrusion–spheronization aids. Drug Development and Industrial Pharmacy 36:11, pages 1364-1376.
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Anikó Szepes, Piroska Szabó-Révész & Mandy Mohnicke. (2007) Water Sorption Behavior and Swelling Characteristics of Starches Subjected to Dielectric Heating. Pharmaceutical Development and Technology 12:6, pages 555-561.
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Articles from other publishers (9)

Namdeo Jadhav, Mukund Gade, Nitin Salunkhe & Anant Paradkar. (2014) Extrusion-Spheronization of Talc using Microcrystalline Cellulose as a Pellet Aid: Part I. Journal of Pharmaceutical Innovation 9:4, pages 321-330.
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F.J. Otero-Espinar, A. Luzardo-Alvarez & J. Blanco-Méndez. (2010) Non-MCC materials as extrusion-spheronization aids in pellets production. Journal of Drug Delivery Science and Technology 20:4, pages 303-318.
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Aleksandra Dukić-Ott, Jean Paul Remon, Paul Foreman & Chris Vervaet. (2007) Immediate release of poorly soluble drugs from starch-based pellets prepared via extrusion/spheronisation. European Journal of Pharmaceutics and Biopharmaceutics 67:3, pages 715-724.
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Markus Thommes & Peter Kleinebudde. (2006) Use of κ-carrageenan as alternative pelletisation aid to microcrystalline cellulose in extrusion/spheronisation. I. Influence of type and fraction of filler. European Journal of Pharmaceutics and Biopharmaceutics 63:1, pages 59-67.
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S. Almeida Prieto, J. Blanco Méndez & F.J. Otero Espinar. (2005) Starch–dextrin mixtures as base excipients for extrusion–spheronization pellets. European Journal of Pharmaceutics and Biopharmaceutics 59:3, pages 511-521.
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Ingunn Tho, Sverre Arne Sande & Peter Kleinebudde. (2003) Disintegrating pellets from a water-insoluble pectin derivative produced by extrusion/spheronisation. European Journal of Pharmaceutics and Biopharmaceutics 56:3, pages 371-380.
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Ingunn Tho, Sverre Arne Sande & Peter Kleinebudde. (2002) Pectinic acid, a novel excipient for production of pellets by extrusion/spheronisation: preliminary studies. European Journal of Pharmaceutics and Biopharmaceutics 54:1, pages 95-99.
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HX Guo, J Heinämäki & J Yliruusi. (2002) Diffusion of a freely water-soluble drug in aqueous enteric-coated pellets. AAPS PharmSciTech 3:2, pages 97-104.
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J.F Pinto, M.H Lameiro & P Martins. (2001) Investigation on the co-extrudability and spheronization properties of wet masses. International Journal of Pharmaceutics 227:1-2, pages 71-80.
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