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Research Article

Scaleup of a Pharmaceutical Granulation in Planetary Mixers

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Pages 145-150 | Received 23 Mar 1998, Accepted 13 Jul 1998, Published online: 22 Apr 1999

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Preetanshu Pandey & Sherif Badawy. (2016) A quality by design approach to scale-up of high-shear wet granulation process. Drug Development and Industrial Pharmacy 42:2, pages 175-189.
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Carlos Ufret & Ken Morris. (2001) Modeling of Powder Blending Using On-line Near-Infrared Measurements. Drug Development and Industrial Pharmacy 27:7, pages 719-729.
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Articles from other publishers (29)

Guillaume Delaplace, Jie Xiao, Felipe Buendia, Romain Jeantet & Xiao Dong Chen. (2023) Framework for choosing energy efficient mixing equipment whatever motions it induces: Example of application for planetary and helical ribbon mixers. Chemical Engineering Research and Design 198, pages 173-183.
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Angga Pratama Herman, Zongyan Zhou, Jieqing Gan & Aibing Yu. (2022) Scaling up studies for mixing of granular materials in rotating drums. Powder Technology 403, pages 117408.
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Angga Pratama Herman, Jieqing Gan, Zongyan Zhou & Aibing Yu. (2022) Discrete particle simulation for mixing of granular materials in ribbon mixers: A scale-up study. Powder Technology 400, pages 117222.
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Abdoulah Ly, Inès Esma Achouri, Ryan Gosselin & Nicolas Abatzoglou. (2021) Wet granulation end point prediction using dimensionless numbers in a mixer torque rheometer: Relationship between capillary and Weber numbers and the optimal wet mass consistency. International Journal of Pharmaceutics 605, pages 120823.
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Maitraye Sen & Salvador García Muñoz. (2021) Development and implementation of a hybrid scale up model for a batch high shear wet granulation operation. AIChE Journal 67:5.
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Angga Pratama Herman, Jieqing Gan & Aibing Yu. (2021) GPU-based DEM simulation for scale-up of bladed mixers. Powder Technology 382, pages 300-317.
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Krista Taipale-Kovalainen, Jarkko Ketolainen, Ossi Korhonen & Tuomas Ervasti. (2020) Converting a batch based high-shear granulation process to a continuous dry granulation process; a demonstration with ketoprofen tablets. European Journal of Pharmaceutical Sciences 151, pages 105381.
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Eun Ha Jang, Yun Sang Park, Min-Soo Kim & Du Hyung Choi. (2020) Model-Based Scale-up Methodologies for Pharmaceutical Granulation. Pharmaceutics 12:5, pages 453.
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Preetanshu Pandey & Sherif I.F. Badawy. 2019. Handbook of Pharmaceutical Wet Granulation. Handbook of Pharmaceutical Wet Granulation 615 650 .
S. Badawy & P. Pandey. 2017. Developing Solid Oral Dosage Forms. Developing Solid Oral Dosage Forms 749 776 .
. 2016. How to Scale-Up a Wet Granulation End Point Scientifically. How to Scale-Up a Wet Granulation End Point Scientifically 67 72 .
Jing Tao, Preetanshu Pandey, Dilbir S. Bindra, Julia Z. Gao & Ajit S. Narang. (2015) Evaluating Scale-Up Rules of a High-Shear Wet Granulation Process. Journal of Pharmaceutical Sciences 104:7, pages 2323-2333.
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Karen P. Hapgood & Rachel M. Smith. 2015. Pharmaceutical Blending and Mixing. Pharmaceutical Blending and Mixing 153 182 .
C. André, J.F. Demeyre, C. Gatumel, H. Berthiaux & G. Delaplace. (2014) Derivation of dimensionless relationships for the agitation of powders of different flow behaviours in a planetary mixer. Powder Technology 256, pages 33-38.
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Leon Shargel & Isadore KanferSalah Ahmed, Ashok Katdare, Venkatesh Naini & Dilip Wadgaonkar. 2013. Generic Drug Product Development. Generic Drug Product Development 95 138 .
C. André, J.F. Demeyre, C. Gatumel, H. Berthiaux & G. Delaplace. (2012) Dimensional analysis of a planetary mixer for homogenizing of free flowing powders: Mixing time and power consumption. Chemical Engineering Journal 198-199, pages 371-378.
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Guillaume Delaplace, Philippe Coppenolle, José Cheio & Fabrice Ducept. (2012) Influence of whip speed ratios on the inclusion of air into a bakery foam produced with a planetary mixer device. Journal of Food Engineering 108:4, pages 532-540.
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Guillaume Delaplace, Laurent Bouvier, Anne Moreau & Christophe Andre. (2011) An arrangement of ideal reactors as a way to model homogenizing processes with a planetary mixer. AIChE Journal 57:7, pages 1678-1683.
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Hans Leuenberger, Maxim Puchkov, Etienne Krausbauer & Gabrielle Betz. (2009) Manufacturing pharmaceutical granules: Is the granulation end-point a myth?. Powder Technology 189:2, pages 141-148.
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Lirong Liu, Michael Levin & Paul Sheskey. 2009. Developing Solid Oral Dosage Forms. Developing Solid Oral Dosage Forms 667 699 .
Xiaorong He, Keith A. Lunday, Liang‐chi Li & Mark J. Sacchetti. (2008) Formulation Development and Process Scale Up of a High Shear Wet Granulation Formulation Containing a Poorly Wettable Drug. Journal of Pharmaceutical Sciences 97:12, pages 5274-5289.
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. 2008. Pharmaceutical Dosage Forms - Tablets. Pharmaceutical Dosage Forms - Tablets 17 64 .
G. Delaplace, Rajeev K. Thakur, L. Bouvier, C. André & C. Torrez. (2007) Dimensional analysis for planetary mixer: Mixing time and Reynolds numbers. Chemical Engineering Science 62:5, pages 1442-1447.
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Hans Leuenberger & Gabriele Betz. 2007. Granulation. Granulation 705 733 .
Anders Darelius, Henric Brage, Anders Rasmuson, Ingela Niklasson Björn & Staffan Folestad. (2006) A volume-based multi-dimensional population balance approach for modelling high shear granulation. Chemical Engineering Science 61:8, pages 2482-2493.
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G. Delaplace, R. Guérin & J. C. Leuliet. (2005) Dimensional analysis for planetary mixer: Modified power and Reynolds numbers. AIChE Journal 51:12, pages 3094-3100.
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Ingela Niklasson Björn, Anders Jansson, Magnus Karlsson, Staffan Folestad & Anders Rasmuson. (2005) Empirical to mechanistic modelling in high shear granulation. Chemical Engineering Science 60:14, pages 3795-3803.
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Hans Leuenberger. (2001) New trends in the production of pharmaceutical granules: the classical batch concept and the problem of scale-up. European Journal of Pharmaceutics and Biopharmaceutics 52:3, pages 279-288.
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A. Faure, P. York & R.C. Rowe. (2001) Process control and scale-up of pharmaceutical wet granulation processes: a review. European Journal of Pharmaceutics and Biopharmaceutics 52:3, pages 269-277.
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