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Research Article

Topical Liposomal Gel of Tretinoin for the Treatment of Acne: Research and Clinical Implications

, , Professor of Pharmaceutics &
Pages 455-464 | Received 06 Apr 1999, Accepted 13 Jan 2000, Published online: 21 Nov 2000

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Ghada M. El-Zaafarany & Maha Nasr. (2021) Insightful exploring of advanced nanocarriers for the topical/transdermal treatment of skin diseases. Pharmaceutical Development and Technology 26:10, pages 1136-1157.
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Antonia Mancuso, Maria Chiara Cristiano, Massimo Fresta & Donatella Paolino. (2020) The Challenge of Nanovesicles for Selective Topical Delivery for Acne Treatment: Enhancing Absorption Whilst Avoiding Toxicity. International Journal of Nanomedicine 15, pages 9197-9210.
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Aleksandra Marchwicka, Alan Cunningham, Ewa Marcinkowska & Geoffrey Brown. (2016) Therapeutic use of selective synthetic ligands for retinoic acid receptors: a patent review. Expert Opinion on Therapeutic Patents 26:8, pages 957-971.
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Nina Dragicevic-Curic & Alfred Fahr. (2012) Liposomes in topical photodynamic therapy. Expert Opinion on Drug Delivery 9:8, pages 1015-1032.
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Gisele A Castro & Lucas AM Ferreira. (2008) Novel vesicular and particulate drug delivery systems for topical treatment of acne. Expert Opinion on Drug Delivery 5:6, pages 665-679.
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Martin Brandl. (2007) Vesicular Phospholipid Gels: A Technology Platform. Journal of Liposome Research 17:1, pages 15-26.
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Josbert M Metselaar & Gert Storm. (2005) Liposomes in the treatment of inflammatory disorders. Expert Opinion on Drug Delivery 2:3, pages 465-476.
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S. S. Bhalerao & A. Raje Harshal. (2003) Preparation, Optimization, Characterization, and Stability Studies of Salicylic Acid Liposomes. Drug Development and Industrial Pharmacy 29:4, pages 451-467.
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V. B. Patel, A. N. Misra & Y. S. Marfatia. (2001) Preparation and Comparative Clinical Evaluation of Liposomal Gel of Benzoyl Peroxide for Acne. Drug Development and Industrial Pharmacy 27:8, pages 863-870.
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Articles from other publishers (31)

SHUBHRIKA CHANDWANI, T. R. SAINI, REENA SONI, SURESH K. PASWAN & PRAKASH K. SONI. (2023) BOX-BEHNKEN DESIGN OPTIMIZATION OF SALICYLIC ACID LOADED LIPOSOMAL GEL FORMULATION FOR TREATMENT OF FOOT CORN. International Journal of Applied Pharmaceutics, pages 220-233.
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Shruti Dudhat, Prabha Singh & Prachi Pimple. (2023) Insights of Lipid Vesicular and Particulate Carrier Mediated Approach for Acne Management. Current Drug Delivery 20:1, pages 57-74.
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Maryam Rezaeizadeh, Amir Eskanlou, Hoda Soltani, Abbas Pardakhty, Mohammad-Hassan Moshafi & Fatemeh Hosseini-Nejad. (2021) Preparation of Stable Clindamycin Phosphate Niosomes by Combination of Sorbitan Esters and their Ethoxylaed Derivatives. Journal of Pharmaceutical Innovation 17:4, pages 1189-1198.
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Parisa Ghasemiyeh, Soliman Mohammadi-Samani, Kiarash Noorizadeh, Ouriel Zadmehr, Shiva Rasekh, Shiva Mohammadi-Samani & Dorsa Dehghan. (2022) Novel topical drug delivery systems in acne management: Molecular mechanisms and role of targeted delivery systems for better therapeutic outcomes. Journal of Drug Delivery Science and Technology 74, pages 103595.
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Muhammad Raza Shah, Muhammad Imran & Shafi Ullah. 2022. Nanocarriers for Organ-Specific and Localized Drug Delivery. Nanocarriers for Organ-Specific and Localized Drug Delivery 135 166 .
Saurabh Shivalkar, Arushi Verma, Vishal Singh & Amaresh Kumar Sahoo. 2021. Nanotechnology in Medicine. Nanotechnology in Medicine 259 280 .
Merve Karpuz, Evren Atlihan-Gundogdu, E. Selin Demir & Zeynep Senyigit. (2021) Radiolabeled Tedizolid Phosphate Liposomes for Topical Application: Design, Characterization, and Evaluation of Cellular Binding Capacity. AAPS PharmSciTech 22:2.
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Niranjan G. Kotla, Bhargavi Chandrasekar, Peadar Rooney, Gandhi Sivaraman, Aitor Larrañaga, K. Vijaya Krishna, Abhay Pandit & Yury Rochev. (2017) Biomimetic Lipid-Based Nanosystems for Enhanced Dermal Delivery of Drugs and Bioactive Agents. ACS Biomaterials Science & Engineering 3:7, pages 1262-1272.
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Sveinung G. Ingebrigtsen, Nataša Škalko-Basnet, Cristiane de Albuquerque Cavalcanti Jacobsen & Ann Mari Holsæter. (2017) Successful co-encapsulation of benzoyl peroxide and chloramphenicol in liposomes by a novel manufacturing method - dual asymmetric centrifugation. European Journal of Pharmaceutical Sciences 97, pages 192-199.
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Evren H. Gökçe, Evren Algın Yapar, Sakine Tuncay Tanrıverdi & Özgen Özer. 2016. Nanobiomaterials in Galenic Formulations and Cosmetics. Nanobiomaterials in Galenic Formulations and Cosmetics 363 393 .
Sanjay Dey, Supriya Datta, Sandipan Dasgupta, Bhaskar Mazumder & Yasvant V. Pathak. 2016. Nanobiomaterials in Galenic Formulations and Cosmetics. Nanobiomaterials in Galenic Formulations and Cosmetics 327 361 .
Mihaela D. Leonida & Ish KumarMihaela D. Leonida & Ish Kumar. 2016. Bionanomaterials for Skin Regeneration. Bionanomaterials for Skin Regeneration 53 60 .
Ryan F. Donnelly & Thakur Raghu Raj SinghVenkata K. Yellepeddi. 2015. Novel Delivery Systems for Transdermal and Intradermal Drug Delivery. Novel Delivery Systems for Transdermal and Intradermal Drug Delivery 125 146 .
Yuanyuan Guan, Tiantian Zuo, Minglu Chang, Fang Zhang, Ting Wei, Wei Shao & Guimei Lin. (2015) Propranolol hydrochloride-loaded liposomal gel for transdermal delivery: Characterization and in vivo evaluation. International Journal of Pharmaceutics 487:1-2, pages 135-141.
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Gihan Fetih, Dina Fathalla & Mahmoud El-Badry. (2014) Liposomal Gels for Site-Specific, Sustained Delivery of Celecoxib: In Vitro and In Vivo Evaluation. Drug Development Research 75:4, pages 257-266.
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Yosra S.R. Elnaggar, Wessam M. El-Refaie, Magda A. El-Massik & Ossama Y. Abdallah. (2014) Lecithin-based nanostructured gels for skin delivery: An update on state of art and recent applications. Journal of Controlled Release 180, pages 10-24.
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Joao Roberto Antonio, Carlos Roberto Antonio, Izabela Lidia Soares Cardeal, Julia Maria Avelino Ballavenuto & Joao Rodrigo Oliveira. (2014) Nanotechnology in Dermatology. Anais Brasileiros de Dermatologia 89:1, pages 126-136.
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Sara BrennerDavid Schairer, MD Chouake, MD Nasir & Adam Friedman. 2013. The Clinical Nanomedicine Handbook. The Clinical Nanomedicine Handbook 85 194 .
A. Nast, B. Dréno, V. Bettoli, K. Degitz, R. Erdmann, A. Y. Finlay, R. Ganceviciene, M. Haedersdal, A. Layton, J.L. López-Estebaranz, F. Ochsendorf, C. Oprica, S. Rosumeck, B. Rzany, A. Sammain, T. Simonart, N.K. Veien, M.V. Živković, C.C. Zouboulis & H. Gollnick. (2012) European Evidence-based (S3) Guidelines for the Treatment of Acne. Journal of the European Academy of Dermatology and Venereology 26, pages 1-29.
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Maria Bernadete Riemma Pierre & Irina dos Santos Miranda Costa. (2011) Liposomal systems as drug delivery vehicles for dermal and transdermal applications. Archives of Dermatological Research 303:9.
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Dimitrios Papakostas, Fiorenza Rancan, Wolfram Sterry, Ulrike Blume-Peytavi & Annika Vogt. (2011) Nanoparticles in dermatology. Archives of Dermatological Research 303:8, pages 533-550.
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J De Leeuw, N Van Der Beek, P Bjerring & HA Martino Neumann. (2010) Photodynamic therapy of acne vulgaris using 5‐aminolevulinic acid 0.5% liposomal spray and intense pulsed light in combination with topical keratolytic agents. Journal of the European Academy of Dermatology and Venereology 24:4, pages 460-469.
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Srinivasan Shanmugam, Chung-Kil Song, Santhoshkumar Nagayya-Sriraman, Rengarajan Baskaran, Chul-Soon Yong, Han-Gon Choi, Dae-Duk Kim, Jong Soo Woo & Bong-Kyu Yoo. (2009) Physicochemical characterization and skin permeation of liposome formulations containing clindamycin phosphate. Archives of Pharmacal Research 32:7, pages 1067-1075.
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J de Leeuw, HC de Vijlder, P Bjerring & HAM Neumann. (2009) Liposomes in dermatology today. Journal of the European Academy of Dermatology and Venereology 23:5, pages 505-516.
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Anja Thielitz & Harald Gollnick. (2008) Topical Retinoids in Acne Vulgaris. American Journal of Clinical Dermatology 9:6, pages 369-381.
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M. Manconi, F. Marongiu, G. Ennas, A. Scano, C. Sinico, D. Valenti & A.M. Fadda. (2008) Liposomes for (trans)dermal delivery of tretinoin: influence of drug concentration and vesicle composition. Journal of Drug Delivery Science and Technology 18:5, pages 309-313.
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Wolfgang Meier & Jörg Schreiber. 2005. Delivery System Handbook for Personal Care and Cosmetic Products. Delivery System Handbook for Personal Care and Cosmetic Products 587 602 .
Vitthal S. Kulkarni. 2005. Delivery System Handbook for Personal Care and Cosmetic Products. Delivery System Handbook for Personal Care and Cosmetic Products 285 302 .
Andrea Krautheim & Harald Gollnick. (2003) Transdermal Penetration of Topical Drugs Used in the Treatment of Acne. Clinical Pharmacokinetics 42:14, pages 1287-1304.
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Andreas Wagner, Karola Vorauer-Uhl & Hermann Katinger. (2002) Liposomes produced in a pilot scale: production, purification and efficiency aspects. European Journal of Pharmaceutics and Biopharmaceutics 54:2, pages 213-219.
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Vandana B. Patel, Ambikanandan Misra & Yogesh S. Marfatia. (2001) Clinical assessment of the combination therapy with liposomal gels of tretinoin and benzoyl peroxide in acne. AAPS PharmSciTech 2:3, pages 1-5.
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