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Pharmaceutical Development and Technology Volume 5, 2000 - Issue 4
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Research Article

The Influence of Varying Precompaction and Main Compaction Profile Parameters on the Mechanical Strength of Compacts

Colleen E. Ruegger Novartis Pharmaceutical Corporation, East Hanover, New Jersey, U.S.A.
&
Metin Çelik Pharmaceutical Technologies International, Inc., Belle Mead, New Jersey, U.S.A.; PTI, Inc., P.O. Box 186, Belle Mead, NJ, 08502, U.S.A.
Pages 495-505 | Received 16 Jun 1999, Accepted 08 Feb 2000, Published online: 21 Nov 2000

Citations (15)

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Read on this site (2)

Claudia Al-Karawi, Thorsten Cech, Florian Bang & Claudia S. Leopold. (2018) Investigation of the tableting behavior of Ibuprofen DC 85 W. Drug Development and Industrial Pharmacy 44:8, pages 1262-1272.
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Elisabeth Peeters, Valérie Vanhoorne, Chris Vervaet & Jean-Paul Remon. (2016) Lubricant sensitivity in function of paddle movement in the forced feeder of a high-speed tablet press. Drug Development and Industrial Pharmacy 42:12, pages 2078-2085.
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Articles from other publishers (13)

Daisuke MizunagaMika KosekiNaoki KamemotoSatoru Watano. (2021) Characterization of Tableting Speed-Dependent Deformation Properties of Active Pharmaceutical Ingredients in Powder Mixtures Using Out-of-Die Method. Chemical and Pharmaceutical Bulletin 69:12, pages 1184-1194.
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Nailla Jiwa, Yildiz Ozalp, Gizem Yegen & Buket Aksu. (2021) Critical Tools in Tableting Research: Using Compaction Simulator and Quality by Design (QbD) to Evaluate Lubricants’ Effect in Direct Compressible Formulation. AAPS PharmSciTech 22:4.
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Alexander Kalies, Hüseyin Özcoban & Claudia S. Leopold. (2019) Performance Characteristics of a Novel Vibration Technique for the Densification of a Powder Bed within a Die of a Rotary Tablet Press — a Proof of Concept. AAPS PharmSciTech 20:4.
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E. Peeters, A.F.T. Silva, M. Fonteyne, T. De Beer, C. Vervaet & J.P. Remon. (2018) Influence of extended dwell time during pre- and main compression on the properties of ibuprofen tablets. European Journal of Pharmaceutics and Biopharmaceutics 128, pages 300-315.
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Takayuki Kamata, Koichi Wada & Hideki Ichikawa. (2018) Dry pre-coating of active pharmaceutical ingredient with submicron-sized hydroxypropylcellulose in dry granulation using roller compactor improves granule properties. Journal of Drug Delivery Science and Technology 43, pages 34-43.
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Parthiban Anbalagan, Paul Wan Sia Heng & Celine Valeria Liew. (2017) Tablet compression tooling – Impact of punch face edge modification. International Journal of Pharmaceutics 524:1-2, pages 373-381.
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Srimanta Sarkar, Shing Ming Ooi, Celine Valeria Liew & Paul Wan Sia Heng. (2015) Influence of Rate of Force Application During Compression on Tablet Capping. Journal of Pharmaceutical Sciences 104:4, pages 1319-1327.
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Sarsvatkumar Patel, Sandeepkumar Dahiya, Changquan Calvin Sun & Arvind Kumar Bansal. (2011) Understanding Size Enlargement and Hardening of Granules on Tabletability of Unlubricated Granules Prepared by Dry Granulation. Journal of Pharmaceutical Sciences 100:2, pages 758-766.
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Ian J Hardy & Walter G Cook. (2003) Predictive and correlative techniques for the design, optimisation and manufacture of solid dosage forms. Journal of Pharmacy and Pharmacology 55:1, pages 3-18.
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Jørn M. Sonnergaard. (2006) Quantification of the compactibility of pharmaceutical powders. European Journal of Pharmaceutics and Biopharmaceutics 63:3, pages 270-277.
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Kyriakos Kachrimanis & Stavros Malamataris. (2005) Compact size and mechanical strength of pharmaceutical diluents. European Journal of Pharmaceutical Sciences 24:2-3, pages 169-177.
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Franziska Freitag & Peter Kleinebudde. (2003) How do roll compaction/dry granulation affect the tableting behaviour of inorganic materials? Comparison of four magnesium carbonates. European Journal of Pharmaceutical Sciences 19:4, pages 281-289.
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Kung‐Hsu Lin, Shan‐Yang Lin & Mei‐Jane Li. (2001) Compression forces and amount of outer coating layer affecting the time‐controlled disintegration of the compression‐coated tablets prepared by direct compression with micronized ethylcellulose. Journal of Pharmaceutical Sciences 90:12, pages 2005-2009.
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