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Pharmaceutical Development and Technology Volume 6, 2001 - Issue 4
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Research Article

Pulmonary Peptide Delivery: Effect of Taste-Masking Excipients on Leuprolide Suspension Metered-Dose Inhalers

Jack Y. Zheng
,
Mou-ying Fulu Pharmaceutical Products Division, Formulation Development Center, Abbott Laboratories, 1401 Sheridan Road, North Chicago, IL, 60064-6246, U.S.A.
,
Dennis Y. Lee Pharmaceutical Products Division, Formulation Development Center, Abbott Laboratories, 1401 Sheridan Road, North Chicago, IL, 60064-6246, U.S.A.
,
Timothy E. Barber Pharmaceutical Products Division, Formulation Development Center, Abbott Laboratories, 1401 Sheridan Road, North Chicago, IL, 60064-6246, U.S.A.
&
Akwete L. Adjei Pharmaceutical Products Division, Formulation Development Center, Abbott Laboratories, 1401 Sheridan Road, North Chicago, IL, 60064-6246, U.S.A.
Pages 521-530 | Received 28 Mar 1999, Accepted 01 Mar 2001, Published online: 04 Apr 2002

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Jean Bousquet & Carmen Dell’Anna. (2008) Modulite® technology in the development of formoterol HFA pMDI: clinical evidence and future opportunities. Expert Review of Respiratory Medicine 2:1, pages 27-36.
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Hugh DC Smyth. (2005) Propellant-driven metered-dose inhalers for pulmonary drug delivery. Expert Opinion on Drug Delivery 2:1, pages 53-74.
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Harmik Sohi, Yasmin Sultana & Roop K. Khar. (2004) Taste Masking Technologies in Oral Pharmaceuticals: Recent Developments and Approaches. Drug Development and Industrial Pharmacy 30:5, pages 429-448.
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Articles from other publishers (8)

Ernest S. Fung, Jillian A. Parker, Alexandra M. Powell & Andrew Maier. (2023) Estimating inhalation bioavailability for peptides and proteins 1 to 10 kDa in size. Regulatory Toxicology and Pharmacology 137, pages 105314.
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Susan HoeMohammed A. BoraeyJames W. IveyWarren H. FinlayReinhard Vehring. (2014) Manufacturing and Device Options for the Delivery of Biotherapeutics. Journal of Aerosol Medicine and Pulmonary Drug Delivery 27:5, pages 315-328.
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Mariam Ibrahim & Lucila Garcia-Contreras. (2013) Mechanisms of absorption and elimination of drugs administered by inhalation. Therapeutic Delivery 4:8, pages 1027-1045.
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Stephen W. Stein, Poonam Sheth & Paul B. Myrdal. (2012) A model for predicting size distributions delivered from pMDIs with suspended drug. International Journal of Pharmaceutics 422:1-2, pages 101-115.
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Sandro R. P. da Rocha, Balaji Bharatwaj & Sowmya Saiprasad. 2011. Controlled Pulmonary Drug Delivery. Controlled Pulmonary Drug Delivery 165 201 .
Shayne Cox GadMichael Hindle. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia.
Lianli Li, Venkatesh Naini & Salah U. Ahmed. (2007) Utilization of a Modified Special‐Cubic Design and an Electronic Tongue for Bitterness Masking Formulation Optimization. Journal of Pharmaceutical Sciences 96:10, pages 2723-2734.
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Paul B. Myrdal, Kelly L. Karlage, Steve W. Stein, Beth A. Brown & Alfred Haynes. (2004) Optimized dose delivery of the peptide cyclosporine using hydrofluoroalkane‐based metered dose inhalers. Journal of Pharmaceutical Sciences 93:4, pages 1054-1061.
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