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Pharmaceutical Development and Technology Volume 9, 2005 - Issue 3
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Research Article

Toward the Development of an Injectable Dosage Form of Propofol: Preparation and Evaluation of Propofol–Sulfobutyl Ether 7‐β‐Cyclodextrin Complex

M. K. Manoj Babu DSM Pharmaceuticals Inc., 5900 NW Greenville Blvd., Greenville, North Carolina, 27834, USA; 4600 Willow Branches Close, Winterville, North Carolina, 28590, USA
&
Tapan N. Godiwala Brody School of Medicine, East Carolina University, Greenville, North Carolina, 27858, USA; 314‐22, Treybrooke Circle, Greenville, North Carolina, 27858, USA
Pages 265-275 | Received 23 Jun 2003, Accepted 19 Oct 2003, Published online: 08 Sep 2004

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S. Basavaraj, Vaibhav Sihorkar, T.R. Shantha Kumar, Prakash Sundaramurthi, Nuggehally R. Srinivas, P. Venkatesh, Mullangi Ramesh & Sunil Kumar Singh. (2006) Bioavailability Enhancement of Poorly Water Soluble and Weakly Acidic New Chemical Entity with 2-Hydroxy Propyl-β-Cyclodextrin: Selection of Meglumine, a Polyhydroxy Base, as a Novel Ternary Component. Pharmaceutical Development and Technology 11:4, pages 443-451.
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Articles from other publishers (10)

Benedikt Wilhelms, Jens Broscheit & Sergey Shityakov. (2023) Chemical Analysis and Molecular Modelling of Cyclodextrin-Formulated Propofol and Its Sodium Salt to Improve Drug Solubility, Stability and Pharmacokinetics (Cytogenotoxicity). Pharmaceuticals 16:5, pages 667.
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Hongfei Chen, Long He, Da Li, Feng Jin & Yanqiu Ai. (2021) Propofol-loaded nanomicelle with improved anesthetic, pharmacokinetic, hemocompatibility, safety, and permeation profiles. Arabian Journal of Chemistry 14:5, pages 103093.
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Thorsteinn Loftsson. (2021) Cyclodextrins in Parenteral Formulations. Journal of Pharmaceutical Sciences 110:2, pages 654-664.
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Thorsteinn Loftsson, Maria D Moya-Ortega, Carmen Alvarez-Lorenzo & Angel Concheiro. (2016) Pharmacokinetics of cyclodextrins and drugs after oral and parenteral administration of drug/cyclodextrin complexes. Journal of Pharmacy and Pharmacology 68:5, pages 544-555.
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Sergey Shityakov, István Puskás, Katalin Pápai, Ellaine Salvador, Norbert Roewer, Carola Förster & Jens-Albert Broscheit. (2015) Sevoflurane-Sulfobutylether-β-Cyclodextrin Complex: Preparation, Characterization, Cellular Toxicity, Molecular Modeling and Blood-Brain Barrier Transport Studies. Molecules 20:6, pages 10264-10279.
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WeiHui Cai, WanDing Deng, HuiHui Yang, XiaoPing Chen & Fang Jin. (2012) A propofol microemulsion with low free propofol in the aqueous phase: Formulation, physicochemical characterization, stability and pharmacokinetics. International Journal of Pharmaceutics 436:1-2, pages 536-544.
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Alexei Merzlikine, Yuriy A. Abramov, Stacy J. Kowsz, V. Hayden Thomas & Takashi Mano. (2011) Development of machine learning models of β-cyclodextrin and sulfobutylether-β-cyclodextrin complexation free energies. International Journal of Pharmaceutics 418:2, pages 207-216.
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Alka Ahuja, Sanjula Baboota, Javed Ali & Gulam Mustafa. 2011. Cyclodextrins in Pharmaceutics, Cosmetics, and Biomedicine. Cyclodextrins in Pharmaceutics, Cosmetics, and Biomedicine 19 43 .
Jaepyoung Cho, Jin Cheol Cho, Pungsok Lee, Mase Lee & Euichaul Oh. (2010) Formulation and evaluation of an alternative triglyceride-free propofol microemulsion. Archives of Pharmacal Research 33:9, pages 1375-1387.
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Abhijit A. Date & Mangal S. Nagarsenker. (2008) Design and Evaluation of Microemulsions for Improved Parenteral Delivery of Propofol. AAPS PharmSciTech 9:1, pages 138-145.
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