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Pharmaceutical Development and Technology Volume 10, 2005 - Issue 2
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Research Article

In Vitro Release of Levonorgestrel from Phase Sensitive and Thermosensitive Smart Polymer Delivery Systems

Sibao Chen Department of Pharmaceutical Sciences, College of Pharmacy, North Dakota State University, Fargo, North Dakota, 58105, USA
&
Jagdish Singh Department of Pharmaceutical Sciences, College of Pharmacy, North Dakota State University, Fargo, North Dakota, 58105, USA
Pages 319-325 | Received 27 Aug 2004, Accepted 29 Oct 2004, Published online: 07 Oct 2008

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Debarupa Dutta Chakraborty, L. K. Nath & Prithviraj Chakraborty. (2018) Recent Progress in Smart Polymers: Behavior, Mechanistic Understanding and Application. Polymer-Plastics Technology and Engineering 57:10, pages 945-957.
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Xian Jun Loh & Jun Li. (2007) Biodegradable thermosensitive copolymer hydrogels for drug delivery. Expert Opinion on Therapeutic Patents 17:8, pages 965-977.
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Lalit Ranakoti, Brijesh Gangil, Prabhakar Bhandari, Tej Singh, Shubham Sharma, Jujhar Singh & Sunpreet Singh. (2023) Promising Role of Polylactic Acid as an Ingenious Biomaterial in Scaffolds, Drug Delivery, Tissue Engineering, and Medical Implants: Research Developments, and Prospective Applications. Molecules 28:2, pages 485.
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Sowmya Sivasankaran & Sriramakamal Jonnalagadda. (2022) Levonorgestrel loaded biodegradable microparticles for injectable contraception: Preparation, characterization and modelling of drug release. International Journal of Pharmaceutics 624, pages 121994.
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Buddhadev Layek. 2021. Tailor-Made and Functionalized Biopolymer Systems. Tailor-Made and Functionalized Biopolymer Systems 723 746 .
Mehran Kurdtabar & Ghasem Rezanejade Bardajee. (2019) Drug release and swelling behavior of magnetic iron oxide nanocomposite hydrogels based on poly(acrylic acid) grafted onto sodium alginate. Polymer Bulletin 77:6, pages 3001-3015.
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Lindsey Lipp, Divya Sharma, Amrita Banerjee & Jagdish Singh. (2020) In Vitro and in Vivo Optimization of Phase Sensitive Smart Polymer for Controlled Delivery of Rivastigmine for Treatment of Alzheimer’s Disease. Pharmaceutical Research 37:3.
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Somayyah Abdul Munim & Zulfiqar Ali Raza. (2018) Poly(lactic acid) based hydrogels: formation, characteristics and biomedical applications. Journal of Porous Materials 26:3, pages 881-901.
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Divya Sharma, Lindsey Lipp, Sanjay Arora & Jagdish Singh. 2019. Materials for Biomedical Engineering. Materials for Biomedical Engineering 449 477 .
A JEROME, S K SRIVASTAVA, R K SHARMA & S K PHULIA. (2017) Efficacy of progesterone implants on induction of cyclicity in anestrous buffaloes. The Indian Journal of Animal Sciences 87:7.
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LiNa Wang, Xiao Lin, YanLong Hong, Lan Shen & Yi Feng. (2017) Hydrophobic mixed solvent induced PLGA-based in situ forming systems for smooth long-lasting delivery of Radix Ophiopogonis polysaccharide in rats. RSC Advances 7:9, pages 5349-5361.
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Arijit Basu, Konda Reddy Kunduru, Sindhu Doppalapudi, Abraham J. Domb & Wahid Khan. (2016) Poly(lactic acid) based hydrogels. Advanced Drug Delivery Reviews 107, pages 192-205.
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Linfeng Wu, Dileep R. Janagam, Timothy D. Mandrell, James R. Johnson & Tao L. Lowe. (2015) Long-Acting Injectable Hormonal Dosage Forms for Contraception. Pharmaceutical Research 32:7, pages 2180-2191.
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Marianne Parent, Cécile Nouvel, Martin Koerber, Anne Sapin, Philippe Maincent & Ariane Boudier. (2013) PLGA in situ implants formed by phase inversion: Critical physicochemical parameters to modulate drug release. Journal of Controlled Release 172:1, pages 292-304.
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Piyush Jain & Ajay K. Banga. (2012) Induction and Inhibition of Crystallization in Drug-in-Adhesive-Type Transdermal Patches. Pharmaceutical Research 30:2, pages 562-571.
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Guang Hui Gao, Yi Li & Doo Sung Lee. 2002. Encyclopedia of Polymer Science and Technology. Encyclopedia of Polymer Science and Technology.
D.J. Overstreet, H.A. Von Recum & B.L. Vernon. 2011. Injectable Biomaterials. Injectable Biomaterials 95 141 .
Yu Tang, Mayura Oak, Rhishikesh Mandke, Buddhadev Layek, Gitanjali Sharma & Jagdish Singh. 2011. Active Implants and Scaffolds for Tissue Regeneration. Active Implants and Scaffolds for Tissue Regeneration 457 479 .
Minh Khanh Nguyen & Doo Sung Lee. (2010) Injectable Biodegradable Hydrogels. Macromolecular Bioscience 10:6, pages 563-579.
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Rubina P. Shaikh, Viness Pillay, Yahya E. Choonara, Lisa C. du Toit, Valence M. K. Ndesendo, Priya Bawa & Shivaan Cooppan. (2010) A Review of Multi-Responsive Membranous Systems for Rate-Modulated Drug Delivery. AAPS PharmSciTech 11:1, pages 441-459.
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Alexandra Fidalgo, Tessy M. Lopez & Laura M. Ilharco. (2008) Wet sol–gel silica matrices as delivery devices for phenytoin. Journal of Sol-Gel Science and Technology 49:3, pages 320-328.
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Kun-Ho Liu, Ting-Yu Liu, San-Yuan Chen & Dean-Mo Liu. (2008) Drug release behavior of chitosan–montmorillonite nanocomposite hydrogels following electrostimulation. Acta Biomaterialia 4:4, pages 1038-1045.
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Chaoliang He, Sung Wan Kim & Doo Sung Lee. (2008) In situ gelling stimuli-sensitive block copolymer hydrogels for drug delivery. Journal of Controlled Release 127:3, pages 189-207.
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Ashok Khanna, Yamini S. Sudha, Sandeep Pillai & Swagat S. Rath. (2008) Molecular modeling studies of poly lactic acid initiation mechanisms. Journal of Molecular Modeling 14:5, pages 367-374.
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Sibao Chen & Jagdish Singh. (2008) Controlled release of growth hormone from thermosensitive triblock copolymer systems: In vitro and in vivo evaluation. International Journal of Pharmaceutics 352:1-2, pages 58-65.
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Sumit Chhabra, Vishal Sachdeva & Somnath Singh. (2007) Influence of end groups on in vitro release and biological activity of lysozyme from a phase-sensitive smart polymer-based in situ gel forming controlled release drug delivery system. International Journal of Pharmaceutics 342:1-2, pages 72-77.
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Somnath Singh, Dean C. Webster & Jagdish Singh. (2007) Thermosensitive polymers: Synthesis, characterization, and delivery of proteins. International Journal of Pharmaceutics 341:1-2, pages 68-77.
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