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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 31, 2001 - Issue 22
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Original Articles

THE DESIGN AND SYNTHESIS OF STRUCTURALLY RELATED MERCAPTOPURINE ANALOGUES: REACTION OF DIMETHYL N-CYANO-DITHIOIMINOCARBONATE WITH 5-AMINOPYRAZOLES

Galal H. Elgemeie Chemistry Department, Faculty of Science, Helwan University, Ain Helwan, Cairo, Egypt
,
Samia R. El-Ezbawy Chemistry Department, Faculty of Science, Helwan University, Ain Helwan, Cairo, Egypt
&
Hany A. El-Aziz Chemistry Department, Faculty of Science, Helwan University, Ain Helwan, Cairo, Egypt
Pages 3453-3458 | Received 20 Mar 2000, Published online: 22 Aug 2006

Citations (22)

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Read on this site (9)

Galal Elgemeie, Farag Altalbawy, Mohammed Alfaidi, Rania Azab & Atef Hassan. (2017) Synthesis, characterization, and antimicrobial evaluation of novel 5-benzoyl-N-substituted amino- and 5-benzoyl-N-sulfonylamino-4-alkylsulfanyl-2-pyridones. Drug Design, Development and Therapy 11, pages 3389-3399.
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Imen Jalloul, Maha Hachicha, Madiha Kammoun, Mohamed Lotfi Efrit & Azaiez Ben Akacha. (2014) Nouvelle Voie de Synthèse de Pyrazolotriazines Phosphonatées. Phosphorus, Sulfur, and Silicon and the Related Elements 189:10, pages 1596-1602.
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GalalH. Elgemeie, ShahinazH. Elsayed & AshrafS. Hassan. (2008) Direct Route to a New Class of Acrylamide Thioglycosides and Their Conversions to Pyrazole Derivatives. Synthetic Communications 38:16, pages 2700-2706.
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Galal H. Elgemeie, Wafaa A. Zaghary, Kamelia M. Amin & Tamer M. Nasr. (2008) A Direct Route to a New Class of Acrylamide Thioglycosides. Journal of Carbohydrate Chemistry 27:6, pages 373-378.
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Galal H. Elgemeie, Ahmed H. Elghandour & Ghada W. Abd Elaziz. (2007) Novel Cyanoketene N,S‐Acetals and Pyrazole Derivatives using Potassium 2‐Cyanoethylene‐1‐thiolates. Synthetic Communications 37:17, pages 2827-2834.
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G. H. Elgemeie, A. M. Elzanaty, A. H. Elghandour & S. A. Ahmed. (2006) Novel Alkylsulfanylisothiazoles and Alkylsulfanylthiophenes Using Sodium α‐Cyanoketene Dithiolates as Starting Materials. Synthetic Communications 36:6, pages 825-834.
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Galal H. Elgemeie, Ahmed H. Elghandour & Ahmed M. Hussein. (2004) Amino Acids in Heterocyclic Synthesis: Novel Synthesis of Pyrano[2,3‐c]pyrazoles, Pyrazolo[3,4‐b]pyridine, and Pyrido[1,2‐a]benzimidazoles. Synthetic Communications 34:18, pages 3293-3302.
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Galal H. Elgemeie, Ahmed H. Elghandour & Ghada W. Abd Elaziz. (2004) Potassium 2‐Cyanoethylene‐1‐thiolate Derivatives: A New Preparative Route to 2‐Cyanoketene S,N‐Acetals and Pyrazole Derivatives. Synthetic Communications 34:18, pages 3281-3291.
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Galal H. Elgemeie & Mona A. Ahmed. (2002) A NEW CLASS OF BIHETEROCYCLIC THIOGLYCOSIDES FROM PYRIDINE-2-(1H)-THIONES. Nucleosides, Nucleotides & Nucleic Acids 21:11-12, pages 837-847.
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Articles from other publishers (13)

Galal H. Elgemeie, Rasha A. Azzam, Wafaa A. Zaghary, Mohammed A. Khedr & Gihad E. Elsherif. (2022) Medicinal Chemistry of Pyrazolopyrimidine Scaffolds Substituted with Different Heterocyclic Nuclei. Current Pharmaceutical Design 28:41, pages 3374-3403.
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Galal H. Elgemeie & Reham A. Mohamed-Ezzat. 2022. New Strategies Targeting Cancer Metabolism. New Strategies Targeting Cancer Metabolism 547 611 .
Ahmad Shaabani, Mohammad Taghi Nazeri & Ronak Afshari. (2018) 5-Amino-pyrazoles: potent reagents in organic and medicinal synthesis. Molecular Diversity 23:3, pages 751-807.
Crossref
Marwa Manachou, Christophe Morell, Henry Chermette & Salima Boughdiri. (2019) Theoretical study of the mechanism and regioselectivity in the formation of pyrazolo[1,5-a]-[1,3,5]-triazines and pyrazolo[1,5-a]-[1,3,5]triazinones: A DFT study. Chemical Physics Letters 727, pages 95-104.
Crossref
Rasha A. Azzam & Galal H. Elgemeie. (2018) Synthesis and antimicrobial evaluation of novel N-substituted 4-ethylsulfanyl-2-pyridones and triazolopyridines. Medicinal Chemistry Research 28:1, pages 62-70.
Crossref
Sheng Song, Shenglan Li, Nana Su, Jinglei Li, Fang Shi & Ming Ye. (2016) Structural characterization, molecular modification and hepatoprotective effect of melanin from Lachnum YM226 on acute alcohol-induced liver injury in mice. Food & Function 7:8, pages 3617-3627.
Crossref
G.H. Elgemeie, K.A. Ahmed, E.A. Ahmed, M.H. Helal & D.M. Masoud. (2015) Synthesis of novel tetrasubstituted thiophenes based dye using sodium a-cyanoketene dithiolates as starting materials. Pigment & Resin Technology 44:6, pages 339-346.
Crossref
Felicia Phei Lin Lim & Anton V. Dolzhenko. (2014) 4-Amino-substituted pyrazolo[1,5-a][1,3,5]triazin-2-amines: a new practical synthesis and biological activity. Tetrahedron Letters 55:49, pages 6684-6688.
Crossref
Henry Insuasty, Sandra Estrada, Jairo Quiroga, Braulio Insuasty, Rodrigo Abonia, Manuel Nogueras & Justo Cobo. (2012) Solvent‐Free Microwave‐Assisted Synthesis of Novel 4‐Hetarylpyrazolo[1,5‐ a ][1,3,5]triazines . Journal of Heterocyclic Chemistry 49:6, pages 1339-1345.
Crossref
G. Hajós & Z. Riedl. 2008. Comprehensive Heterocyclic Chemistry III. Comprehensive Heterocyclic Chemistry III 765 817 .
Henry Insuasty, Martín Estrada, Edward Cortés, Jairo Quiroga, Braulio Insuasty, Rodrigo Abonía, Manuel Nogueras & Justo Cobo. (2006) Regioselective synthesis of novel 4-aryl-2-ethylthio-7-methyl pyrazolo[1,5-a]-[1,3,5]-triazines. Tetrahedron Letters 47:31, pages 5441-5443.
Crossref
Galal H. Elgemeie, Samia R. El‐Ezbawy & Hany A. El‐Aziz. (2010) ChemInform Abstract: The Design and Synthesis of Structurally Related Mercaptopurine Analogues: Reaction of Dimethyl N‐Cyanodithioiminocarbonate with 5‐Aminopyrazoles.. ChemInform 33:3.
Crossref
Carmen Ochoa & Pilar Goya. 2002. A Critical Review of the 2001 Literature Preceded by Two Chapter on Current Heterocyclic Topics. A Critical Review of the 2001 Literature Preceded by Two Chapter on Current Heterocyclic Topics 310 331 .

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