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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 33, 2003 - Issue 6
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Original Articles

A Convenient Procedure for the Synthesis of O6-Benzylguanine Derivatives by Phase Transfer Catalysis

, , , , , , , , , & show all
Pages 941-952 | Received 02 Apr 2002, Published online: 17 Aug 2006

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Qi‐Huang Zheng, Ji‐Quan Wang, Xuan Liu, Xiangshu Fei, Bruce H. Mock, Barbara E. Glick‐Wilson, Michael L. Sullivan, Sudhanshu P. Raikwar, Thomas A. Gardner, Chinghai Kao & Gary D. Hutchins. (2004) An Improved Total Synthesis of PET HSV‐tk Gene Reporter Probe 9‐(4‐[18F]Fluoro‐3‐hydroxymethylbutyl)guanine ([18F]FHBG). Synthetic Communications 34:4, pages 689-704.
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Hiroko Koyama, Hiroshi Ikenuma, Hiroshi Toda, Goro Kondo, Masaki Hirano, Masaya Kato, Junichiro Abe, Takashi Yamada, Toshihiko Wakabayashi, Kengo Ito, Atsushi Natsume & Masaaki Suzuki. (2017) Synthesis of PET probe O6-[(3-[11C]methyl)benzyl]guanine by Pd0-mediated rapid C-[11C]methylation toward imaging DNA repair protein O6-methylguanine-DNA methyltransferase in glioblastoma. Bioorganic & Medicinal Chemistry Letters 27:9, pages 1892-1896.
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Mingzhang Gao, Min Wang, Kathy D. Miller & Qi-Huang Zheng. (2012) Simple synthesis of carbon-11-labeled chromen-4-one derivatives as new potential PET agents for imaging of DNA-dependent protein kinase (DNA-PK) in cancer. Applied Radiation and Isotopes 70:8, pages 1558-1563.
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Nadejda Valiaeva, Mark N. Prichard, R. Mark Buller, James R. Beadle, Caroll B. Hartline, Kathy A. Keith, Jill Schriewer, Julissa Trahan & Karl Y. Hostetler. (2009) Antiviral evaluation of octadecyloxyethyl esters of (S)-3-hydroxy-2-(phosphonomethoxy)propyl nucleosides against herpesviruses and orthopoxviruses. Antiviral Research 84:3, pages 254-259.
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Ji-Quan Wang, Emiko L. Kreklau, Barbara J. Bailey, Leonard C. Erickson & Qi-Huang Zheng. (2005) Synthesis and preliminary biological evaluation of O6-[4-(2-[18F]fluoroethoxymethyl)benzyl]guanine as a novel potential PET probe for the DNA repair protein O6-alkylguanine-DNA alkyltransferase in cancer chemotherapy. Bioorganic & Medicinal Chemistry 13:20, pages 5779-5786.
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Xuan Liu, Ji‐Quan Wang & Qi‐Huang Zheng. (2005) Lipophilicity coefficients of potential tumor imaging agents, positron‐labeled O 6 ‐benzylguanine derivatives . Biomedical Chromatography 19:5, pages 379-384.
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Ji-Quan Wang, Xiangshu Fei, Thomas A. Gardner, Gary D. Hutchins & Qi-Huang Zheng. (2005) Synthesis of 2-amino-6-(4-[11C]methoxyphenylthio)-9-[2-(phosphonomethoxy)ethyl]purine bis(2,2,2-trifluoroethyl) ester as a novel potential PET gene reporter probe for HBV and HSV-tk in cancers. Bioorganic & Medicinal Chemistry 13:2, pages 549-556.
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Carmen Ochoa, Pilar Goya & Cristina Gómez. 2005. A critical review of the 2003 literature preceded by two chapters on current heterocyclic topics. A critical review of the 2003 literature preceded by two chapters on current heterocyclic topics 385 404 .
Qi‐Huang Zheng & et al. et al.. (2003) A Convenient Procedure for the Synthesis of O 6 ‐Benzylguanine Derivatives by Phase Transfer Catalysis. . ChemInform 34:28.
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Qi‐Huang Zheng, Xuan Liu, Xiangshu Fei, Ji‐Quan Wang, David W. Ohannesian, Leonard C. Erickson, K. Lee Stone, Tanya D. Martinez, Kathy D. Miller & Gary D. Hutchins. (2002) Synthesis of radiolabeled O 6 ‐benzylguanine derivatives as new potential PET tumor imaging agents for the DNA repair protein O 6 ‐alkylguanine‐DNA alkyltransferase . Journal of Labelled Compounds and Radiopharmaceuticals 45:14, pages 1239-1252.
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