Trityl-Directed Regiospecific Synthesis of 2,3-Disubstituted Bioimidazoles

Pooja Chandana Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, S.A.S. Nagar, Punjab, India

Amit Nayyar Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, S.A.S. Nagar, Punjab, India

Rahul Jain Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, S.A.S. Nagar, Punjab, IndiaCorrespondence[email protected]

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Komal Sharma, Krishna K. Sharma, Amit Mahindra, Naina Sehra, Nitin Bagra, Shams Aaghaz, Rajesh Parmar, Gajanan K. Rathod & Rahul Jain. (2023) Design, synthesis, and applications of ring‐functionalized histidines in peptide‐based medicinal chemistry and drug discovery. Medicinal Research Reviews 43:4, pages 775-828.
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Yang Wang, Fan Lei, Xiaolong Li, Yi He, Jue Li, Rui Qiu, Xueying Wu, Li Hai & Yong Wu. (2015) Structure-based design, synthesis and anti-influenza A virus activities of substituted phenyl-coupled heterocyclic ethylamide derivatives. Chemical Research in Chinese Universities 31:6, pages 942-951.
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Xue-Li Geng, Jia Wang, Guo-Xing Li, Peng Chen, Shu-Fang Tian & Jin Qu. (2008) Kinetic Resolution of Racemic Alcohols Using Thioamide Modified 1-Methyl-histidine Methyl Ester. The Journal of Organic Chemistry 73:21, pages 8558-8562.
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Bruno Delest, Prosper Nshimyumukiza, Olivier Fasbender, Bernard Tinant, Jacqueline Marchand-Brynaert, Francis Darro & Raphaël Robiette. (2008) Divergent and Regioselective Synthesis of 1,2,4- and 1,2,5-Trisubstituted Imidazoles. The Journal of Organic Chemistry 73:17, pages 6816-6823.
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Surendra Kumar Nayak, Vikramdeep Monga, Navneet Kaur & Rahul Jain. (2009) Facile regiospecific syntheses of N ‐α, N ‐1(τ)‐dialkyl‐l‐histidines . Journal of Heterocyclic Chemistry 44:6, pages 1265-1269.
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Navneet Kaur, Vikramdeep Monga & Rahul Jain. (2004) Facile one-step synthesis of N-α-Boc-1-alkyl-l-histidines. Tetrahedron Letters 45:37, pages 6883-6885.
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Pooja Chandana, Amit Nayyar & Rahul Jain. (2003) Trityl‐Directed Regiospecific Synthesis of 2,3‐Disubstituted Bioimidazoles.. ChemInform 34:50.
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Trityl-Directed Regiospecific Synthesis of 2,3-Disubstituted Bioimidazoles

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Trityl-Directed Regiospecific Synthesis of 2,3-Disubstituted Bioimidazoles

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