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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 34, 2004 - Issue 5
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Original Articles

A Practical Two‐Step Synthesis of 3‐Alkyl‐2,3‐dihydro‐1H‐isoindolin‐1‐ones

Yuan‐Ping Ruan Department of Chemistry, Xiamen University, Xiamen, Fujian, 361005, China
,
Ming‐De Chen Department of Chemistry, Xiamen University, Xiamen, Fujian, 361005, China
,
Ming‐Zhu He Department of Chemistry, Xiamen University, Xiamen, Fujian, 361005, China
,
Xiang Zhou Department of Chemistry, Xiamen University, Xiamen, Fujian, 361005, China
&
Pei‐Qiang Huang Department of Chemistry, Xiamen University, Xiamen, Fujian, 361005, ChinaCorrespondence[email protected]
Pages 853-861 | Received 21 Aug 2003, Published online: 20 Aug 2006

Citations (20)

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Zujian Lan, Xiaoyu Xu, Wenkai Xu, Jin Li, Zengrong Liang, Xuefei Zhang, Ming Lei & Chunshun Zhao. (2015) Discovery of 3-n-butyl-2,3-dihydro-1H-isoindol-1-one as a potential anti-ischemic stroke agent. Drug Design, Development and Therapy 9, pages 3377-3391.
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Articles from other publishers (19)

Mohammad Sadeq Mousavi, Antonia Di Mola & Antonio Massa. (2023) Multifaceted Behavior of 2‐Cyanobenzaldehyde and 2‐Acylbenzonitriles in the Synthesis of Isoindolinones, Phthalides and Related Heterocycles. European Journal of Organic Chemistry 26:24.
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Jules Brom, Antoine Maruani, Laurent Micouin & Erica Benedetti. (2023) Light-Driven Reductive Cleavage of Sulfonamides Promoted by Thiourea Organophotosensitizers. The Journal of Organic Chemistry 88:9, pages 5923-5935.
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Veerababurao Kavala, Chen-Yu Wang, Cheng-Chuan Wang, Prakash Bhimrao Patil, ChiaChi Fang, Chun-Wei Kuo & Ching-Fa Yao. (2020) Copper-catalysed synthesis of 3-hydroxyisoindolin-1-ones from benzylcyanide 2-iodobenzamides. Organic & Biomolecular Chemistry 18:5, pages 988-998.
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Antonia Di Mola, Antonio Macchia, Consiglia Tedesco, Giovanni Pierri, Laura Palombi, Rosanna Filosa & Antonio Massa. (2019) Synthetic Strategies and Cascade Reactions of 2‐Cyanobenzophenones for the Access to Diverse 3,3‐Disubstituted Isoindolinones and 3‐Aryl‐3‐Hydroxyisoindolinones. ChemistrySelect 4:17, pages 4820-4826.
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Antonia Di Mola, Miriam Di Martino, Vito Capaccio, Giovanni Pierri, Laura Palombi, Consiglia Tedesco & Antonio Massa. (2018) Synthesis of 2-Acetylbenzonitriles and Their Reactivity in Tandem Reactions with Carbon and Hetero Nucleophiles: Easy Access to 3,3-Disubstituted Isoindolinones. European Journal of Organic Chemistry 2018:14, pages 1699-1708.
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Yiliang Zhang, Li He & Lei Shi. (2018) Asymmetric hydrogenolysis of racemic 3-substitued-3-hydroxy-isoindolin-1-ones employing SPINOL-derived chiral phosphoric acid. Tetrahedron Letters 59:16, pages 1592-1595.
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Jinhai Shen, Qihua You, Qi Fu, Changsheng Kuai, Huabin Huang, Li Zhao & Zhixia Zhuang. (2017) Base-Promoted Cascade C–C Coupling/ N -α-sp 3 C–H Hydroxylation for the Regiospecific Synthesis of 3-Hydroxyisoindolinones . Organic Letters 19:19, pages 5170-5173.
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Richard C. LarockRichard C. Larock & Tuanli Yao. 2018. Comprehensive Organic Transformations. Comprehensive Organic Transformations 1 85 .
Richard C. LarockRichard C. Larock & Xiaoxia Zhang. 2018. Comprehensive Organic Transformations. Comprehensive Organic Transformations 1 189 .
Chao Li, Kun Jiang, Qin Ouyang, Tian-Yu Liu & Ying-Chun Chen. (2016) [3 + 1]- and [3 + 2]-Cycloadditions of Azaoxyallyl Cations and Sulfur Ylides. Organic Letters 18:11, pages 2738-2741.
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Bohumír Grüner, Václav Šícha, Drahomír Hnyk, Michael G.S. Londesborough & Ivana Císařová. (2015) The Synthesis and Structural Characterization of Polycyclic Derivatives of Cobalt Bis(dicarbollide)(1 – ) . Inorganic Chemistry 54:7, pages 3148-3158.
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Chen-ming Hu, Lian-you Zheng, Ya-zhong Pei & Xu Bai. (2013) Synthesis of novel 3-aryl isoindolinone derivatives. Chemical Research in Chinese Universities 29:3, pages 487-494.
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Zh. R. Sagirova, E. V. Starodubtseva, O. V. Turova & M. G. Vinogradov. (2014) Hydrogenolysis of the C-O bond of hydroxylactams as a convenient method for the synthesis of substituted isoindolin-1-ones. Russian Chemical Bulletin 62:4, pages 1032-1037.
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Vangelis Agouridas, Frédéric Capet, Axel Couture, Eric Deniau & Pierre Grandclaudon. (2011) A highly diastereoselective synthesis of isoindolinone-centered Meyers’ tetracyclic lactams. Application to the asymmetric synthesis of 3-alkylisoindolinones. Tetrahedron: Asymmetry 22:13, pages 1441-1447.
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Xiaolei Yu, Youming Wang, Guiping Wu, Haibin Song, Zhenghong Zhou & Chuchi Tang. (2011) Organocatalyzed Enantioselective Synthesis of Quaternary Carbon‐Containing Isoindolin‐1‐ones. European Journal of Organic Chemistry 2011:16, pages 3060-3066.
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Gerald L. Larson & James L. Fry. 2009. Ionic and Organometallic‐Catalyzed Organosilane Reductions. Ionic and Organometallic‐Catalyzed Organosilane Reductions 1 746 .
Gerald L. Larson & James L. Fry. 2004. Organic Reactions. Organic Reactions 1 737 .
Ming-De Chen, Ming-Zhu He, Xiang Zhou, Li-Qiang Huang, Yuan-Ping Ruan & Pei-Qiang Huang. (2005) Studies on the diastereoselective reductive alkylation of (R)-phenylglycinol derived phthalimide: observation of stereoelectronic effects. Tetrahedron 61:5, pages 1335-1344.
Crossref
Yuan‐Ping Ruan, Ming‐De Chen, Ming‐Zhu He, Xiang Zhou & Pei‐Qiang Huang. (2004) A Practical Two‐Step Synthesis of 3‐Alkyl‐2,3‐dihydro‐1H‐isoindolin‐1‐ones.. ChemInform 35:31.
Crossref

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