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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 34, 2004 - Issue 13
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Original Articles

Zirconium(IV) Chloride Mediated Cyclodehydration of 1,2‐Diacylhydrazines: A Convenient Synthesis of 2,5‐Diaryl 1,3,4‐Oxadiazoles

G. V. M. Sharma Discovery Laboratory, Organic Chemistry Division‐III, Indian Institute of Chemical Technology, Hyderabad, 500 007, IndiaCorrespondence[email protected]
,
Asra Begum Discovery Laboratory, Organic Chemistry Division‐III, Indian Institute of Chemical Technology, Hyderabad, 500 007, India
,
Rakesh Discovery Laboratory, Organic Chemistry Division‐III, Indian Institute of Chemical Technology, Hyderabad, 500 007, India
&
Palakodety Radha Krishna Discovery Laboratory, Organic Chemistry Division‐III, Indian Institute of Chemical Technology, Hyderabad, 500 007, India
Pages 2387-2391 | Received 02 Mar 2004, Published online: 10 Jan 2011

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KinjalD. Patel, ShraddhaM. Prajapati, ShyamaliN. Panchal & HiteshD. Patel. (2014) Review of Synthesis of 1,3,4-Oxadiazole Derivatives. Synthetic Communications 44:13, pages 1859-1875.
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David Ellis, PatrickS. Johnson, Andrew Nortcliffe & Simon Wheeler. (2010) Improved Method for the Preparation of Oxadiazoles from Diacyl Hydrazines. Synthetic Communications 40:20, pages 3021-3026.
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SantoshP. Pardeshi, SachinS. Patil & VivekD. Bobade. (2010) N-Chlorosuccinimide/1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU)–Mediated Synthesis of 2,5-Disubstituted 1,3,4-Oxadiazoles. Synthetic Communications 40:11, pages 1601-1606.
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D. M. Pore, S. M. Mahadik & U. V. Desai. (2008) Trichloroisocyanuric Acid–Mediated One-Pot Synthesis of Unsymmetrical 2,5-Disubstituted 1,3,4-Oxadiazoles at Ambient Temperature. Synthetic Communications 38:18, pages 3121-3128.
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Articles from other publishers (21)

Shivani Saxena, Rajnish Kumar, Avijit Mazumder, Sunita Kumari, Divya Sharma, Sagar Joshi & Vikas Sharma. (2023) A Review on Synthetic Strategies for Useful Oxadiazole Derivatives in Psychological Disorders. Mini-Reviews in Organic Chemistry 20:4, pages 324-332.
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Sunita Kumari, Rajnish Kumar, Avijit Mazumder, Salahuddin, Shivani Saxena, Divya Sharma & Sagar Joshi. (2022) A Comprehensive Review on Synthetic Approaches and Biological Activities of 1,3,4-oxadiazole. Mini-Reviews in Organic Chemistry 19:8, pages 906-919.
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Sunita Kumari, Rajnish Kumar, Avijit Mazumder, Salahuddin, Shivani Saxena, Divya Sharma, Sagar Joshi & Mohd. Mustaqeem Abdullah. (2022) Recent Updates on Synthetic Strategies and Biological Potential of 1,3,4- oxadiazole: Review. Letters in Organic Chemistry 19:9, pages 689-704.
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Kuantao Mao, Yangyang Ma, Leiyang Lv & Zhiping Li. (2022) [4+1] Cyclization of α‐CF 3 Carbonyls with Hydrazides: Synthesis of 1,3,4‐Oxadiazoles under Ambient Conditions . Asian Journal of Organic Chemistry 11:8.
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Valentin Karabelyov, Magdalena Kondeva-Burdina & Violina T. Angelova. (2021) Synthetic approaches to unsymmetrical 2,5-disubstituted 1,3,4-oxadiazoles and their MAO-B inhibitory activity. A review. Bioorganic & Medicinal Chemistry 29, pages 115888.
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Mojtaba LashkariSeyyed Jalal RoudbarakiMajid Ghashang. (2020) Preparation of 1,3,4-oxadiazole derivatives via supported and unsupported phosphinium dibromide reagents. Canadian Journal of Chemistry 98:11, pages 670-675.
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Soheir Shaker & Magda Marzouk. (2016) Utilization of Cyanoacetohydrazide and Oxadiazolyl Acetonitrile in the Synthesis of Some New Cytotoxic Heterocyclic Compounds. Molecules 21:2, pages 155.
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A. Paun, N. D. Hadade, C. C. Paraschivescu & M. Matache. (2016) 1,3,4-Oxadiazoles as luminescent materials for organic light emitting diodes via cross-coupling reactions. Journal of Materials Chemistry C 4:37, pages 8596-8610.
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Qiang Li, Yi Tao, Dongfang Xu, Haobing Zhang & Liping Duan. (2014) One‐pot Synthesis of 2,5‐Disubstituted‐1,3,4‐oxadiazoles Based on the Reaction of N , N ‐Dimethyl Amides with Acid Hydrazides . Journal of the Chinese Chemical Society 61:6, pages 665-670.
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Sushma Singh, Laxmi K. Sharma, Apoorv Saraswat, Ibadur R. Siddiqui & Rana K. Pal Singh. (2013) Electrochemical oxidation of aldehyde-N-arylhydrazones into symmetrical-2,5-disubstituted-1,3,4-oxadiazoles. Research on Chemical Intermediates 40:3, pages 947-960.
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S. Singh, L. K. Sharma, A. Saraswat, M. K. Srivastava, I. R. Siddiqui & R. K. P. Singh. (2014) Anodic Cyclization: A Protocol for the Green Synthesis of 2,5-Disubstituted 1,3,4-Oxadiazoles. Chemistry of Heterocyclic Compounds 49:10, pages 1508-1514.
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Codruţa C. Paraschivescu, Mihaela Matache, Cristian Dobrotă, Alina Nicolescu, Cătălin Maxim, Călin Deleanu, Ileana C. Fărcăşanu & Niculina D. Hădade. (2013) Unexpected Formation of N -(1-(2-Aryl-hydrazono)isoindolin-2-yl)benzamides and Their Conversion into 1,2-(Bis-1,3,4-oxadiazol-2-yl)benzenes . The Journal of Organic Chemistry 78:6, pages 2670-2679.
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Z. Ribcovskaia & F. Macaev. (2012) Synthesis of Mono-Substituted and Simmetrically 2, 5-Disubstituted 1, 3, 4-Oxadiazoles. Chemistry Journal of Moldova 7:2, pages 136-142.
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Cledualdo Soares de Oliveira, Bruno Freitas Lira, José Maria Barbosa-Filho, Jorge Gonçalo Fernandez Lorenzo & Petrônio Filgueiras de Athayde-Filho. (2012) Synthetic Approaches and Pharmacological Activity of 1,3,4-Oxadiazoles: A Review of the Literature from 2000–2012. Molecules 17:9, pages 10192-10231.
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Agnieszka Kudelko. (2012) Reactions of α-mercaptocarboxylic acid hydrazides with triethyl orthoesters: synthesis of 1,3,4-thiadiazin-5(6H)-ones and 1,3,4-oxadiazoles. Tetrahedron 68:18, pages 3616-3625.
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Agnieszka Kudelko, Wojciech Zieliński & Krzysztof Ejsmont. (2011) The reaction of optically active α-aminocarboxylic acid hydrazides with triethyl orthoesters. Tetrahedron 67:40, pages 7838-7845.
Crossref
Kai Zhang, Youtian Tao, Chuluo Yang, Han You, Yang Zou, Jingui Qin & Dongge Ma. (2008) Synthesis and Properties of Carbazole Main Chain Copolymers with Oxadiazole Pendant toward Bipolar Polymer Host: Tuning the HOMO/LUMO Level and Triplet Energy. Chemistry of Materials 20:23, pages 7324-7331.
Crossref
J. Suwiński & W. Szczepankiewicz. 2008. Comprehensive Heterocyclic Chemistry III. Comprehensive Heterocyclic Chemistry III 397 466 .
Lise-Lotte Gundersen, Frode Rise, Kjell Undheim & Yvan Le Huérou. 2001. Encyclopedia of Reagents for Organic Synthesis. Encyclopedia of Reagents for Organic Synthesis.
Clint A. James, Brigitte Poirier, Christiane Grisé, Alain Martel & Edward H. Ruediger. (2006) General synthesis of tetrasubstituted alkenyl-1,3,4-oxadiazoles. Tetrahedron Letters 47:4, pages 511-514.
Crossref
G. V. M. Sharma, Asra Begum, Rakesh Rakesh & Palakodety Radha Krishna. (2004) Zirconium(IV) Chloride Mediated Cyclodehydration of 1,2‐Diacylhydrazines: A Convenient Synthesis of 2,5‐Diaryl 1,3,4‐Oxadiazoles.. ChemInform 35:46.
Crossref

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