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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 34, 2004 - Issue 23
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Original Articles

Synthesis of Some Novel Fluorinated Pyrazolo[3,4‐b]Pyridines

S. P. Singh Department of Chemistry, University of Kurukshetra, Kurukshetra, Haryana, India
,
Rajesh Naithani Department of Chemistry, University of Illinois at Chicago, Chicago, Illinois, 60607, USACorrespondence[email protected]
,
Ranjana Aggarwal Department of Chemistry, University of Kurukshetra, Kurukshetra, Haryana, India
&
Om Prakash Department of Chemistry, University of Kurukshetra, Kurukshetra, Haryana, India
Pages 4359-4367 | Received 02 Aug 2004, Published online: 10 Jan 2011

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Sundaravel Vivek Kumar, Shanmugam Muthusubramanian & Subbu Perumal. (2019) Recent Progress in the Synthesis of Pyrazolopyridines and Their Derivatives. Organic Preparations and Procedures International 51:1, pages 1-89.
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Articles from other publishers (19)

Felipe S. Stefanello, Yuri G. Kappenberg, Juliane N. Araújo, Steffany Z. Franceschini, Marcos A.P. Martins, Nilo Zanatta, Bernardo A. Iglesias & Helio G. Bonacorso. (2022) Trifluoromethyl-substituted aryldiazenyl-pyrazolo[1,5-a]pyrimidin-2-amines: Regioselective synthesis, structure, and optical properties. Journal of Fluorine Chemistry 255-256, pages 109967.
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Viktor V. Khutoryanskiy, Angelina V. Biitseva & Pavel K. Mykhailiuk. (2016) Synthesis of Functionalized 2‐Trifluoromethylquinolines and their Heteroaromatic Analogues. Asian Journal of Organic Chemistry 5:4, pages 513-520.
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Michael De Rosa, David Arnold, Douglas Hartline, Linda Truong, Roman Verner, Tianwei Wang & Christian Westin. (2015) Effect of Bronsted Acids and Bases, and Lewis Acid (Sn 2+ ) on the Regiochemistry of the Reaction of Amines with Trifluoromethyl-β-diketones: Reaction of 3-Aminopyrrole to Selectively Produce Regioisomeric 1 H -Pyrrolo[3,2- b ]pyridines . The Journal of Organic Chemistry 80:24, pages 12288-12299.
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Navjeet Kaur. (2015) Benign Approaches for the Microwave-assisted Synthesis of Five-membered 1,2- N , N -heterocycles . Journal of Heterocyclic Chemistry 52:4, pages 953-973.
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Vinod Kumar, Girish Kumar Gupta, Kamalneet Kaur & Randhir Singh. (2013) 4-Fluorophenylhydrazones as potential COX-2 inhibitors: a novel, efficient, one pot solid phase synthesis, docking study and pharmacological evaluation. Medicinal Chemistry Research 22:12, pages 5890-5900.
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Navneet Chandak, Satish Kumar, Pawan Kumar, Chetan Sharma, Kamal R. Aneja & Pawan K. Sharma. (2013) Exploration of antimicrobial potential of pyrazolo[3,4-b]pyridine scaffold bearing benzenesulfonamide and trifluoromethyl moieties. Medicinal Chemistry Research 22:11, pages 5490-5503.
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Ranjana Aggarwal, Virender Kumar, Anshul Bansal, Dionisia Sanz & Rosa M. Claramunt. (2012) Multi-component solvent-free versus stepwise solvent mediated reactions: Regiospecific formation of 6-trifluoromethyl and 4-trifluoromethyl-1H-pyrazolo[3,4-b]pyridines. Journal of Fluorine Chemistry 140, pages 31-37.
Crossref
A. S. Golubev, G. S. Starostin, K. S. Chunikhin, A. S. Peregudov, K. C. Rodygin, S. A. Rubtsova, P. A. Slepukhin, A. V. Kuchin & N. D. Chkanikov. (2011) Synthesis of new fluorine-containing pyrazolo[3,4-b]pyridinones as promising drug precursors. Russian Chemical Bulletin 60:4, pages 733-745.
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Pawan K. Sharma, Karan Singh, Surender Kumar, Pawan Kumar, S. N. Dhawan, Sukhbir Lal, Holger Ulbrich & Gerd Dannhardt. (2010) Synthesis and anti-inflammatory evaluation of some pyrazolo[3,4-b]pyridines. Medicinal Chemistry Research 20:2, pages 239-244.
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Shi-Wen Huang, Jin-Sheng Cheng, Li Qian & Suo-Yi Huang. (2010) Facile microwave-assisted synthesis of bis-pyrazol pyrimidine derivatives via an N-alkylation reaction. Research on Chemical Intermediates 37:1, pages 1-9.
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Sanghee Lee & Seung Bum Park. (2009) An Efficient One-Step Synthesis of Heterobiaryl Pyrazolo[3,4- b ]pyridines via Indole Ring Opening . Organic Letters 11:22, pages 5214-5217.
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Ranjana Aggarwal, Garima Sumran, Rosa M. Claramunt, Dionisia Sanz & J. Elguero. (2009) Synthesis and structural characterization of pyrazol-1′-ylpyrazolo[1,5-a]pyrimidines by multinuclear NMR spectroscopy. Journal of Molecular Structure 934:1-3, pages 96-102.
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Sandip B. Bharate, Tushar R. Mahajan, Yogesh R. Gole, Mahesh Nambiar, T.T. Matan, Asha Kulkarni-Almeida, Sarala Balachandran, H. Junjappa, Arun Balakrishnan & Ram A. Vishwakarma. (2008) Synthesis and evaluation of pyrazolo[3,4-b]pyridines and its structural analogues as TNF-α and IL-6 inhibitors. Bioorganic & Medicinal Chemistry 16:15, pages 7167-7176.
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E. E. Emelina, A. A. Petrov, S. I. Selivanov & D. V. Filyukov. (2011) α-aminoazoles in synthesis of heterocycles: III. 4-trifluoromethylpyrazolo[3,4-b]pyridines: Synthesis and structure. Russian Journal of Organic Chemistry 44:2, pages 251-256.
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B.R. Buckley. 2008. Comprehensive Heterocyclic Chemistry III. Comprehensive Heterocyclic Chemistry III 431 491 .
Shujiang Tu, Qian Wang, Yan Zhang, Jianing Xu, Jinpeng Zhang, Xiaotong Zhu & Feng Shi. (2009) Design and synthesis of new and significative bifunctional compounds containing two pyrazolo[3,4‐ b ]pyridine nucleis through multicomponent reaction under microwave irradiation . Journal of Heterocyclic Chemistry 44:4, pages 811-814.
Crossref
Vadim A. Soloshonok, Hironari Ohkura & Manabu Yasumoto. (2006) Novel sequence of two base-catalyzed 1,3 proton shifts and [1,2] Wittig rearrangement in the synthesis of 2,4-bis-(trifluoromethyl)-6-phenylpyridine. Journal of Fluorine Chemistry 127:6, pages 708-711.
Crossref
Vadim A. Soloshonok, Hironari Ohkura & Manabu Yasumoto. (2006) Unusual condensation of 1,1,1,5,5,5-hexafluoropentane-2,4-dione with (R)-phenylglycinol. Mendeleev Communications 16:3, pages 165-167.
Crossref
S. P. Singh, Rajesh Naithani, Ranjana Aggarwal & Om Prakash. (2005) Synthesis of Some Novel Fluorinated Pyrazolo[3,4‐b]pyridines.. ChemInform 36:18.
Crossref

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