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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 34, 2004 - Issue 24
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Original Articles

First Report on the Abnormal Dearylation/Alkylation Reaction in One‐Pot Hantzch Synthesis with 6‐Amino‐1,3‐Dimethyl Uracil

Anu Agarwal Medicinal and Process Chemistry Division, Central Drug Research Institute, Lucknow, 226001, India
&
Prem M. S. Chauhan Medicinal and Process Chemistry Division, Central Drug Research Institute, Lucknow, 226001, IndiaCorrespondence[email protected] [email protected]
Pages 4447-4461 | Received 06 Aug 2004, Published online: 10 Jan 2011

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Chetan K. Jadhav, Amol S. Nipate, Asha V. Chate & Charansingh H. Gill. (2022) An Organocatalytic Newer Synthetic Approach toward the Access of Dihydropyrido[2,3-d] Pyrimidine in Water: A Perfect Synergy for Eco-compatible Organic Synthesis. Polycyclic Aromatic Compounds 42:10, pages 7368-7384.
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Mohamed Adnen Hadj Ayed, Thouraya Gmiza, Jamel Eddine Khiari & Béchir Ben Hassine. (2012) Efficient One-Pot Synthesis of Substituted Pyrido[2,3-d]pyrimidines from Vinamidinium and Chloropropeniminium Salts. Synthetic Communications 42:12, pages 1824-1831.
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Articles from other publishers (20)

Arvind Singh, Bhupinder Kaur, Aditi Sharma, Anu Priya, Manmeet Kaur, Mussarat Shamim & Bubun Banerjee. (2023) One-pot multi-component synthesis of diverse bioactive heterocyclic scaffolds involving 6-aminouracil or its N -methyl derivatives as a versatile reagent . Physical Sciences Reviews 8:10, pages 3475-3499.
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Zeinab Hussain, Magdy A. Ibrahim, Nasser M. El-Gohary, Yassin A. Gabr, Hassan A. Allimony & Al-Shimaa Badran. (2023) Utility of 6-Aminouracils for Building Substituted and Heteroannulated Pyrimidines: A Comprehensive Review. HETEROCYCLES 106:4, pages 594.
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Kiran R. Khillare, Dipak S. Aher, Laxmikant D. Chavan & Sunil G. Shankarwar. (2021) Cesium salt of 2-molybdo-10-tungstophosphoric acid as an efficient and reusable catalyst for the synthesis of uracil derivatives via a green route . RSC Advances 11:54, pages 33980-33989.
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Tushar Das, Amit Ranjan, Lesław Sieroń, Waldemar Maniukiewicz & Subrata Das. (2021) Direct Synthesis, Characterization and Theoretical Studies of N‐(6‐Amino‐1,3‐dimethyl‐2,4‐dioxo‐1,2,3,4‐tetrahydropyrimidin‐5‐yl)benzamide Derivatives. ChemistrySelect 6:4, pages 726-732.
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Boshra Mirhosseini-Eshkevari, Manzarbanoo Esnaashari & Mohammad Ali Ghasemzadeh. (2019) Novel Brönsted Acidic Ionic Liquids Confined in UiO-66 Nanocages for the Synthesis of Dihydropyrido[2,3- d ]Pyrimidine Derivatives under Solvent-Free Conditions . ACS Omega 4:6, pages 10548-10557.
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Tiago Zaminelli, Elisa Magli, Francesco Frecentese, Caroline H. Lescano, Rafael Campos, Irene Saccone, Angela Corvino, Paola Di Vaio, Flavia Giordano, Paolo Luciano, Ferdinando Fiorino, Elisa Perissutti, Vincenzo Santagada, Beatrice Severino, Giuseppe Caliendo & Gilberto De Nucci. (2019) Synthesis and Pharmacological Screening of Pyridopyrimidines as Effective Anti‐Diarrheal Agents through the Suppression of Cyclic Nucleotide Accumulation. ChemistryOpen 8:4, pages 464-475.
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Majid M. Heravi, Vahideh Zadsirjan, Mahzad Dehghani & Tahereh Ahmadi. (2018) Towards click chemistry: Multicomponent reactions via combinations of name reactions. Tetrahedron 74:27, pages 3391-3457.
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Manouchehr Mamaghani & Roghayeh Hossein Nia. (2016) Recent Developments in the MCRs Synthesis of Pyridopyrimidines and Spiro‐Pyridopyrimidines. Journal of Heterocyclic Chemistry 54:3, pages 1700-1722.
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Ghodsi Mohammadi Ziarani, Narges Hosseini Nasab & Negar Lashgari. (2016) Synthesis of heterocyclic scaffolds through 6-aminouracil-involved multicomponent reactions. RSC Advances 6:45, pages 38827-38848.
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Subhasis Samai, Ganesh Chandra Nandi, Sushobhan Chowdhury & Maya Shankar Singh. (2011) l-Proline catalyzed synthesis of densely functionalized pyrido[2,3-d]pyrimidines via three-component one-pot domino Knoevenagel aza-Diels–Alder reaction. Tetrahedron 67:33, pages 5935-5941.
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Ghazaleh Imani Shakibaei, Afsaneh Feiz, Hamid Reza Khavasi, Ali Abolhasani Soorki & Ayoob Bazgir. (2010) Simple Three-Component Method for the Synthesis of Spiroindeno[1,2- b ]pyrido[2,3- d ]pyrimidine-5,3′-indolines . ACS Combinatorial Science 13:1, pages 96-99.
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V. D. Dyachenko & E. N. Karpov. (2011) Aliphatic aldehydes in the synthesis of carbo- and heterocycles: Part II. Synthesis of six- and seven-membered rings, bicyclic compounds, and macrocycles. Russian Journal of Organic Chemistry 47:1, pages 1-29.
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Ezzat Rafiee, Sara Eavani, Solmaz Rashidzadeh & Mohammad Joshaghani. (2009) Silica supported 12-tungstophosphoric acid catalysts for synthesis of 1,4-dihydropyridines under solvent-free conditions. Inorganica Chimica Acta 362:10, pages 3555-3562.
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I. B. Dzvinchuk. (2009) Dearylation with aromatization on cyclocondensation of 4-(dimethyl-amino)benzaldehyde, 2-phenacylaza-heterocycles, and 1,3-[N,C]dinucleophiles. Chemistry of Heterocyclic Compounds 45:1, pages 85-92.
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Alexander Y. KotsByung-Kwon ChoiMaria E. Estrella-Jimenez, Cirle A. Warren, Scott R. Gilbertson, Richard L. Guerrant & Ferid Murad. (2008) Pyridopyrimidine derivatives as inhibitors of cyclic nucleotide synthesis: Application for treatment of diarrhea. Proceedings of the National Academy of Sciences 105:24, pages 8440-8445.
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E.S.H. El Ashry & N. Rashed. 2008. Comprehensive Heterocyclic Chemistry III. Comprehensive Heterocyclic Chemistry III 759 845 .
N. A. Hassan, M. I. Hegab, F. M. Abdel-Motti, S. H. A. Hebah, F. M. E. Abdel-Megeid & A. I. Hashem. (2007) Three-component, one-pot synthesis of pyrimido[4,5- b ]-quinoline and pyrido[2,3- d ]pyrimidine derivatives . Journal of Heterocyclic Chemistry 44:4, pages 775-782.
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I. B. Dzvinchuk & M. O. Lozinskii. (2007) The p-(dimethylamino)benzaldehyde modification of Hantzsch reaction: Synthesis of 6-(1H-benzimidazol-2-yl)pyrido[2,3-d]pyrimidino-2,4(1H, 3H)-diones. Chemistry of Heterocyclic Compounds 43:4, pages 480-484.
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Anu Agarwal, Ramesh, Ashutosh, Neena Goyal, Prem M.S. Chauhan & Suman Gupta. (2005) Dihydropyrido[2,3-d]pyrimidines as a new class of antileishmanial agents. Bioorganic & Medicinal Chemistry 13:24, pages 6678-6684.
Crossref
Anu Agarwal & Prem M. S. Chauhan. (2005) First Report on the Abnormal Dearylation/Alkylation Reaction in One‐Pot Hantzch Synthesis with 6‐Amino‐1,3‐dimethyl Uracil.. ChemInform 36:21.
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