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A review of current approaches to identifying human genes involved in myopia

, BSc(Hons), , PhD MCOptom FAAO & , MPhil PhD FIBMS
Pages 4-22 | Received 13 Mar 2007, Accepted 17 May 2007, Published online: 15 Apr 2021

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Kai Xiong Cheong, Rita Yu Yin Yong, Mellisa Mei Hui Tan, Frederick Lian Kheng Tey & Bryan Chin Hou Ang. (2021) Association of SNTB1 with High Myopia. Current Eye Research 46:1, pages 144-150.
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Kai Xiong Cheong, Rita Yu Yin Yong, Mellisa Mei Hui Tan, Frederick Lian Kheng Tey & Bryan Chin Hou Ang. (2020) Association of VIPR2 and ZMAT4 with high myopia. Ophthalmic Genetics 41:1, pages 41-48.
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Katie M Williams & Christopher J Hammond. (2016) GWAS in myopia: insights into disease and implications for the clinic. Expert Review of Ophthalmology 11:2, pages 101-110.
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Lili Dai, Ying Li, Chun Yu Du, Ling Min Gong, Cheng Cheng Han, Xiao Guang Li, Pan Fan & Song Bin Fu. (2012) Ten SNPs of PAX6, Lumican, and MYOC genes are not associated with high myopia in Han Chinese. Ophthalmic Genetics 33:3, pages 171-178.
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Articles from other publishers (28)

Kim Hung Leung, Shumeng Luo, Regina Kwarteng, Sin-Guang Chen, Maurice K. H. Yap, Chien-Ling Huang & Shea Ping Yip. (2019) The myopia susceptibility locus vasoactive intestinal peptide receptor 2 (VIPR2) contains variants with opposite effects. Scientific Reports 9:1.
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Haiyan WuLingxi JiangRui ZhengDongyan LuoXiaoqi LiuFang HaoZhilin JiangBo GongZhenglin YangYi Shi. (2018) Genetic Association Study Between the COL11A1 and COL18A1 Genes and High Myopia in a Han Chinese Population . Genetic Testing and Molecular Biomarkers 22:6, pages 359-365.
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Ljiljana Sretić. (2018) Association between fingerprint patterns and myopia. The University Thought - Publication in Natural Sciences 8:2, pages 15-18.
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V. Galvis, A. Tello, P.A. Camacho, M.M. Parra & J. Merayo-Lloves. (2017) Bio-environmental factors associated with myopia: An updated review. Archivos de la Sociedad Española de Oftalmología (English Edition) 92:7, pages 307-325.
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V. Galvis, A. Tello, P.A. Camacho, M.M. Parra & J. Merayo-Lloves. (2017) Los factores bioambientales asociados a la miopía: una revisión actualizada. Archivos de la Sociedad Española de Oftalmología 92:7, pages 307-325.
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Bo Jiang, Yanan Huo, Yangshun Gu & Jianyong Wang. (2016) The role of microRNAs in myopia. Graefe's Archive for Clinical and Experimental Ophthalmology 255:1, pages 7-13.
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Yanzheng Song, Fengju Zhang, Yanyan Zhao, Mingshen Sun, Jun Tao, Yanchuang Liang, Ling Ma, Yanqiu Yu, Jianhua Wang & Junfeng Hao. (2016) Enlargement of the Axial Length and Altered Ultrastructural Features of the Sclera in a Mutant Lumican Transgenic Mouse Model. PLOS ONE 11:10, pages e0163165.
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Fang-yu Lin, Zhu Huang, Ning Lu, Wei Chen, Hui Fang & Wei Han. (2016) Controversial opinion: evaluation of EGR1 and LAMA2 loci for high myopia in Chinese populations中国汉族人群病理性高度近视与EGR1和LAMA2基因多态位点的关联分析. Journal of Zhejiang University-SCIENCE B 17:3, pages 225-235.
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Miao He, Wei Wang, Dina Ragoonundun & Wenyong Huang. (2014) Meta-Analysis of the Association between Lumican Gene Polymorphisms and Susceptibility to High Myopia. PLoS ONE 9:6, pages e98748.
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A. Landmann & E. Bechrakis. (2013) Anlage versus UmweltNature or nurture. Der Ophthalmologe 110:12, pages 1179-1184.
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Shea Ping Yip, Choi Chu Li, Wai Chi Yiu, Wing Hong Hung, Wai Wa Lam, Man Chi Lai, Po Wah Ng, Wai Yan Fung, Patrick HW Chu, Bo Jiang, Henry HL Chan & Maurice KH Yap. (2013) A novel missense mutation in the NYX gene associated with high myopia . Ophthalmic and Physiological Optics 33:3, pages 346-353.
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Wai Chi Yiu, Maurice K. H. Yap, Wai Yan Fung, Po Wah Ng & Shea Ping Yip. (2013) Genetic Susceptibility to Refractive Error: Association of Vasoactive Intestinal Peptide Receptor 2 (VIPR2) with High Myopia in Chinese. PLoS ONE 8:4, pages e61805.
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Miao-miao Zhu, Maurice KH Yap, Daniel WH Ho, Wai Yan Fung, Po Wah Ng, Yang-shun Gu & Shea Ping Yip. (2012) Investigating the relationship between UMODL1 gene polymorphisms and high myopia: a case–control study in Chinese. BMC Medical Genetics 13:1.
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Daniel W. H. Ho, Maurice K. H. Yap, Po Wah Ng, Wai Yan Fung & Shea Ping Yip. (2012) Association of High Myopia with Crystallin Beta A4 (CRYBA4) Gene Polymorphisms in the Linkage-Identified MYP6 Locus. PLoS ONE 7:6, pages e40238.
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Lei Feng, T. Rowan Candy & Yabo Yang. (2012) Severe Myopic Anisometropia in a Chinese Family. Optometry and Vision Science 89:4, pages 507-511.
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Zhiqiang Yu, Jiaqi Zhou, Xueli Chen, Xingtao Zhou, Xinghuai Sun & Renyuan Chu. (2012) Polymorphisms in the CTNND2 Gene and 11q24.1 Genomic Region Are Associated with Pathological Myopia in a Chinese Population . Ophthalmologica 228:2, pages 123-129.
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Yang Gao, Panfeng Wang, Shiqiang Li, Xueshan Xiao, Xiaoyun Jia, Xiangming Guo & Qingjiong Zhang. (2012) Common variants in chromosome 4q25 are associated with myopia in Chinese adults. Ophthalmic and Physiological Optics 32:1, pages 68-73.
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Bo Jiang, Maurice K. H. Yap, Kim Hung Leung, Po Wah Ng, Wai Yan Fung, Wai Wa Lam, Yang-shun Gu & Shea Ping Yip. (2011) PAX6 Haplotypes Are Associated with High Myopia in Han Chinese. PLoS ONE 6:5, pages e19587.
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R Wojciechowski. (2011) Nature and nurture: the complex genetics of myopia and refractive error. Clinical Genetics 79:4, pages 301-320.
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Chia-Lang Hsu, Yen-Hua Huang, Chien-Ting Hsu & Ueng-Cheng Yang. (2011) Prioritizing disease candidate genes by a gene interconnectedness-based approach. BMC Genomics 12:Suppl 3, pages S25.
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Yan-shu Yu, Lin-ling Wang, Ye Shen, Maurice K. H. Yap, Shea-ping Yip & Wei Han. (2010) Investigation of the association between all-trans-retinol dehydrogenase (RDH8) polymorphisms and high myopia in Chinese. Journal of Zhejiang University SCIENCE B 11:11, pages 836-841.
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Paul N. Baird, Maria Schäche & Mohamed Dirani. (2010) The GEnes in Myopia (GEM) study in understanding the aetiology of refractive errors. Progress in Retinal and Eye Research 29:6, pages 520-542.
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Weihua Meng, Jacqueline Butterworth, Francois Malecaze & Patrick Calvas. (2010) Axial length: An underestimated endophenotype of myopia. Medical Hypotheses 74:2, pages 252-253.
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Hideo Nakanishi, Ryo Yamada, Norimoto Gotoh, Hisako Hayashi, Kenji Yamashiro, Noriaki Shimada, Kyoko Ohno-Matsui, Manabu Mochizuki, Masaaki Saito, Tomohiro Iida, Keitaro Matsuo, Kazuo Tajima, Nagahisa Yoshimura & Fumihiko Matsuda. (2009) A Genome-Wide Association Analysis Identified a Novel Susceptible Locus for Pathological Myopia at 11q24.1. PLoS Genetics 5:9, pages e1000660.
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Zuzana Kubistova, Frantisek Mrazek & Martin Petrek. (2009) POLYMORPHISMS OF THE IMMUNE RESPONSE GENES:SELECTED BIOLOGICAL, METHODICAL AND MEDICAL ASPECTS. Biomedical Papers 153:2, pages 93-102.
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Elise Ciner, Grace Ibay, Robert Wojciechowski, Debra Dana, Taura N. Holmes, Joan E. Bailey-Wilson & Dwight Stambolian. (2009) Genome-wide Scan of African-American and White Families for Linkage to Myopia. American Journal of Ophthalmology 147:3, pages 512-517.e2.
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Donald O. Mutti & Karla Zadnik. (2009) Has Near Work's Star Fallen?. Optometry and Vision Science 86:2, pages 76-78.
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RB Fillingim, MR Wallace, DM Herbstman, M Ribeiro-Dasilva & R Staud. (2008) Genetic contributions to pain: a review of findings in humans. Oral Diseases 14:8, pages 673-682.
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