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Research Papers

Drug delivery to the posterior segment of the eye through hydrogel contact lenses

, PhD, , , PharmD & , DVM PhD
Pages 212-218 | Received 17 May 2010, Accepted 06 Sep 2010, Published online: 15 Apr 2021

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Thorsteinn Loftsson. (2022) Topical drug delivery to the retina: obstacles and routes to success. Expert Opinion on Drug Delivery 19:1, pages 9-21.
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Jennifer J. Kang-Mieler, Emily Dosmar, Wenqiang Liu & William F. Mieler. (2017) Extended ocular drug delivery systems for the anterior and posterior segments: biomaterial options and applications. Expert Opinion on Drug Delivery 14:5, pages 611-620.
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Yuko Shikamura, Yoshiko Yamazaki, Toru Matsunaga, Takao Sato, Akira Ohtori & Kakuji Tojo. (2016) Hydrogel Ring for Topical Drug Delivery to the Ocular Posterior Segment. Current Eye Research 41:5, pages 653-661.
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Mariko Nakano, Catherine M. Lockhart, Edward J. Kelly & Allan E. Rettie. (2014) Ocular cytochrome P450s and transporters: roles in disease and endobiotic and xenobiotic disposition. Drug Metabolism Reviews 46:3, pages 247-260.
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Stephen G Schwartz, Ingrid U Scott, Harry W Flynn$suffix/text()$suffix/text() & Michael W Stewart. (2014) Drug delivery techniques for treating age-related macular degeneration. Expert Opinion on Drug Delivery 11:1, pages 61-68.
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Articles from other publishers (23)

Pinal Chaudhari, Vivek M. Ghate & Shaila A. Lewis. (2021) Next-generation contact lenses: Towards bioresponsive drug delivery and smart technologies in ocular therapeutics. European Journal of Pharmaceutics and Biopharmaceutics 161, pages 80-99.
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Nadia Toffoletto, Benilde Saramago & Ana Paula Serro. (2020) Therapeutic Ophthalmic Lenses: A Review. Pharmaceutics 13:1, pages 36.
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Xin Fan, Cesar Torres-Luna, Marjan Azadi, Roman Domszy, Naiping Hu, Arthur Yang & Allan E. David. (2020) Evaluation of commercial soft contact lenses for ocular drug delivery: A review. Acta Biomaterialia 115, pages 60-74.
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Assumpta Peral, Alejandro Martinez-Aguila, Cristina Pastrana, Fernando Huete-Toral, Carlos Carpena-Torres & Gonzalo Carracedo. (2020) Contact Lenses as Drug Delivery System for Glaucoma: A Review. Applied Sciences 10:15, pages 5151.
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Francesco Baino & Saeid Kargozar. (2020) Regulation of the Ocular Cell/Tissue Response by Implantable Biomaterials and Drug Delivery Systems. Bioengineering 7:3, pages 65.
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Valeria De Matteis & Loris Rizzello. (2020) Noble Metals and Soft Bio-Inspired Nanoparticles in Retinal Diseases Treatment: A Perspective. Cells 9:3, pages 679.
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Sheetal Devi, Vipin Saini, Manish Kumar, Shailendra Bhatt, Sumeet Gupta & Aman Deep. (2019) A Novel Approach of Drug Localization through Development of Polymeric Micellar System Containing Azelastine HCl for Ocular Delivery. Pharmaceutical Nanotechnology 7:4, pages 314-327.
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Debby Chang, Kinam Park & Amin Famili. (2019) Hydrogels for sustained delivery of biologics to the back of the eye. Drug Discovery Today 24:8, pages 1470-1482.
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Shabir Hassan & Yu Shrike Zhang. 2019. Microfluidics for Pharmaceutical Applications. Microfluidics for Pharmaceutical Applications 281 305 .
Jiawen Xu, Yingyan Xue, Gaoyong Hu, Tianyu Lin, Jingxin Gou, Tian Yin, Haibing He, Yu Zhang & Xing Tang. (2018) A comprehensive review on contact lens for ophthalmic drug delivery. Journal of Controlled Release 281, pages 97-118.
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Komal Parmar, Jayvadan K. Patel, Deepak Bhatia & Yashwant V. Pathak. 2018. Drug Delivery for the Retina and Posterior Segment Disease. Drug Delivery for the Retina and Posterior Segment Disease 397 409 .
Komal Parmar & Jayvadan K. Patel. 2018. Drug Delivery for the Retina and Posterior Segment Disease. Drug Delivery for the Retina and Posterior Segment Disease 229 239 .
Sai Prachetan Balguri, Goutham R. Adelli, Akshaya Tatke, Karthik Yadav Janga, Prakash Bhagav & Soumyajit Majumdar. (2017) Melt-Cast Noninvasive Ocular Inserts for Posterior Segment Drug Delivery. Journal of Pharmaceutical Sciences 106:12, pages 3515-3523.
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Mohd Abul Kalam & Aws Alshamsan. (2017) Poly (d, l-lactide-co-glycolide) nanoparticles for sustained release of tacrolimus in rabbit eyes. Biomedicine & Pharmacotherapy 94, pages 402-411.
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Abhirup Mandal, Rohit Bisht, Ilva D. Rupenthal & Ashim K. Mitra. (2017) Polymeric micelles for ocular drug delivery: From structural frameworks to recent preclinical studies. Journal of Controlled Release 248, pages 96-116.
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Frances Lasowski & Heather Sheardown. (2016) Atropine and Roscovitine Release from Model Silicone Hydrogels. Optometry and Vision Science 93:4, pages 404-411.
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Eugen Barbu. 2015. Encyclopedia of Biomedical Polymers and Polymeric Biomaterials. Encyclopedia of Biomedical Polymers and Polymeric Biomaterials 5742 5758 .
Barbara Wirostko, MaryJane Rafii, David A. Sullivan, Julia Morelli & Juan Ding. (2015) Novel Therapy to Treat Corneal Epithelial Defects: A Hypothesis with Growth Hormone. The Ocular Surface 13:3, pages 204-212.e1.
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George Chatzipirpiridis, Olgaç Ergeneman, Juho Pokki, Franziska Ullrich, Stefano Fusco, José A. Ortega, Kartik M. Sivaraman, Bradley J. Nelson & Salvador Pané. (2015) Electroforming of Implantable Tubular Magnetic Microrobots for Wireless Ophthalmologic Applications. Advanced Healthcare Materials 4:2, pages 209-214.
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Yunfeng Shi, Hongling Lv, Yeyun Fu, Qingjun Lu, Jingxiang Zhong, Dong Ma, Yuexin Huang & Wei Xue. (2013) Preparation and characterization of a hydrogel carrier to deliver gatifloxacin and its application as a therapeutic contact lens for bacterial keratitis therapy. Biomedical Materials 8:5, pages 055007.
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Ana Guzman-AranguezBasilio ColligrisJesús Pintor. (2013) Contact Lenses: Promising Devices for Ocular Drug Delivery. Journal of Ocular Pharmacology and Therapeutics 29:2, pages 189-199.
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Changhai Lu, Roshan B. Yoganathan, Michael Kociolek & Christine Allen. (2013) Hydrogel Containing Silica Shell Cross-Linked Micelles for Ocular Drug Delivery. Journal of Pharmaceutical Sciences 102:2, pages 627-637.
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Alex Hui, Heather Sheardown & Lyndon Jones. (2012) Acetic and Acrylic Acid Molecular Imprinted Model Silicone Hydrogel Materials for Ciprofloxacin-HCl Delivery. Materials 5:12, pages 85-107.
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