Advanced search
Publication Cover
Molecular and Cellular Biology Volume 37, 2017 - Issue 11
Submit an article Journal homepage
356
Views
42
CrossRef citations to date
0
Altmetric
Research Article

Coordinated Hsp110 and Hsp104 Activities Power Protein Disaggregation in Saccharomyces cerevisiae

Jayasankar Mohanakrishnan KaimalDepartment of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden
,
Ganapathi KandasamyDepartment of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden
,
Fabian GasserDepartment of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden
&
Claes AndréassonDepartment of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, SwedenCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-8948-0685
ORCID Icon
Article: e00027-17 | Received 18 Jan 2017, Accepted 06 Mar 2017, Published online: 17 Mar 2023

Citations (42)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Amit K. Verma, Chetana Tamadaddi, Yogesh Tak, Silviya S. Lal, Sierra J. Cole, Justin K. Hines & Chandan Sahi. (2019) The expanding world of plant J-domain proteins. Critical Reviews in Plant Sciences 38:5-6, pages 382-400.
Read now

Articles from other publishers (41)

Liqing Hu, Cancan Sun, Justin M. Kidd, Jizhong Han, Xianjun Fang, Hongtao Li, Qingdai Liu, Aaron E. May, Qianbin Li, Lei Zhou & Qinglian Liu. (2023) A first-in-class inhibitor of Hsp110 molecular chaperones of pathogenic fungi. Nature Communications 14:1.
Crossref
Verena Kohler & Claes Andréasson. (2023) Reversible protein assemblies in the proteostasis network in health and disease. Frontiers in Molecular Biosciences 10.
Crossref
Amanda B. Abildgaard, Vasileios Voutsinos, Søren D. Petersen, Fia B. Larsen, Caroline Kampmeyer, Kristoffer E. Johansson, Amelie Stein, Tommer Ravid, Claes Andréasson, Michael K. Jensen, Kresten Lindorff-Larsen & Rasmus Hartmann-Petersen. (2023) HSP70-binding motifs function as protein quality control degrons. Cellular and Molecular Life Sciences 80:1.
Crossref
Andreas Bracher & Jacob Verghese. 2023. The Networking of Chaperones by Co-Chaperones. The Networking of Chaperones by Co-Chaperones 1 39 .
Celine Caillet, Melissa Louise Stofberg, Victor Muleya, Addmore Shonhai & Tawanda Zininga. (2022) Host cell stress response as a predictor of COVID-19 infectivity and disease progression. Frontiers in Molecular Biosciences 9.
Crossref
Yueqin Li, Yingdi Li, Ruoyun Li, Lianliang Liu, Yingjie Miao, Peifang Weng & Zufang Wu. (2021) Metabolic changes of Issatchenkia orientalis under acetic acid stress by transcriptome profile using RNA-sequencing. International Microbiology 25:3, pages 417-426.
Crossref
Zulfi Nur Amrina Rosyada, Mokhamad Fakhrul Ulum, Ligaya I. T. A. Tumbelaka, Dedy Duryadi SolihinBambang Purwantara & Erdogan Memili. (2022) Implications of sperm heat shock protein 70-2 in bull fertility. Veterinary World, pages 1456-1466.
Crossref
Haneul Yoo, Jared A.M. Bard, Evgeny V. Pilipenko & D. Allan Drummond. (2022) Chaperones directly and efficiently disperse stress-triggered biomolecular condensates. Molecular Cell 82:4, pages 741-755.e11.
Crossref
Nathan M. Rowarth, Bruce A. Curtis, Anthony L. Einfeldt, John M. Archibald, Christian R. Lacroix & Arunika H. L. A. N. Gunawardena. (2021) RNA-Seq analysis reveals potential regulators of programmed cell death and leaf remodelling in lace plant (Aponogeton madagascariensis). BMC Plant Biology 21:1.
Crossref
Austin Royster, Sheema Mir & Mohammad Ayoub Mir. (2021) A novel approach for the purification of aggregation prone proteins. PLOS ONE 16:11, pages e0260143.
Crossref
Jan S. Fassler, Sydney Skuodas, Daniel L. Weeks & Bryan T. Phillips. (2021) Protein Aggregation and Disaggregation in Cells and Development. Journal of Molecular Biology 433:21, pages 167215.
Crossref
Hongtao Li, Liqing Hu, Crist William Cuffee, Mahetab Mohamed, Qianbin Li, Qingdai Liu, Lei Zhou & Qinglian Liu. (2021) Interdomain interactions dictate the function of the Candida albicans Hsp110 protein Msi3. Journal of Biological Chemistry 297:3, pages 101082.
Crossref
Benjamin C Creekmore, Yi-Wei Chang & Edward B Lee. (2021) The Cryo-EM Effect: Structural Biology of Neurodegenerative Disease Proteostasis Factors. Journal of Neuropathology & Experimental Neurology 80:6, pages 494-513.
Crossref
Stefanie Andersson, Antonia Romero, Joana Isabel Rodrigues, Sansan Hua, Xinxin Hao, Therese Jacobson, Vivien Karl, Nathalie Becker, Arghavan Ashouri, Sebastien Rauch, Thomas Nyström, Beidong Liu & Markus J. Tamás. (2021) Genome-wide imaging screen uncovers molecular determinants of arsenite-induced protein aggregation and toxicity. Journal of Cell Science 134:11.
Crossref
Masashi Yoshida, Sae Kato, Shizu Fukuda & Shingo Izawa. (2021) Acquired Resistance to Severe Ethanol Stress in Saccharomyces cerevisiae Protein Quality Control. Applied and Environmental Microbiology 87:6.
Crossref
Verena Kohler & Claes Andréasson. (2020) Hsp70-mediated quality control: should I stay or should I go?. Biological Chemistry 401:11, pages 1233-1248.
Crossref
Yuval Reiss, Elisheva Gur & Tommer Ravid. (2020) Releasing the Lockdown: An Emerging Role for the Ubiquitin-Proteasome System in the Breakdown of Transient Protein Inclusions. Biomolecules 10:8, pages 1168.
Crossref
Jessica Tittelmeier, Carl Alexander Sandhof, Heidrun Maja Ries, Silke Druffel‐Augustin, Axel Mogk, Bernd Bukau & Carmen Nussbaum‐Krammer. (2020) The HSP110/HSP70 disaggregation system generates spreading‐competent toxic α‐synuclein species. The EMBO Journal 39:13.
Crossref
Fabian den Brave, Lucas V. Cairo, Chandhuru Jagadeesan, Carmen Ruger-Herreros, Axel Mogk, Bernd Bukau & Stefan Jentsch. (2020) Chaperone-Mediated Protein Disaggregation Triggers Proteolytic Clearance of Intra-nuclear Protein Inclusions. Cell Reports 31:9, pages 107680.
Crossref
Chi-ting Ho, Tomas Grousl, Oren Shatz, Areeb Jawed, Carmen Ruger-Herreros, Marije Semmelink, Regina Zahn, Karsten Richter, Bernd Bukau & Axel Mogk. (2019) Cellular sequestrases maintain basal Hsp70 capacity ensuring balanced proteostasis. Nature Communications 10:1.
Crossref
Claes Andréasson, Martin Ott & Sabrina Büttner. (2019) Mitochondria orchestrate proteostatic and metabolic stress responses. EMBO reports 20:10.
Crossref
Anna E Masser, Wenjing Kang, Joydeep Roy, Jayasankar Mohanakrishnan Kaimal, Jany Quintana-Cordero, Marc R Friedländer & Claes Andréasson. (2019) Cytoplasmic protein misfolding titrates Hsp70 to activate nuclear Hsf1. eLife 8.
Crossref
James Shorter & Daniel R. Southworth. (2019) Spiraling in Control: Structures and Mechanisms of the Hsp104 Disaggregase. Cold Spring Harbor Perspectives in Biology 11:8, pages a034033.
Crossref
Roja Babazadeh, Doryaneh Ahmadpour, Song Jia, Xinxin Hao, Per Widlund, Kara Schneider, Frederik Eisele, Laura Dolz Edo, Gertien J. Smits, Beidong Liu & Thomas Nystrom. (2019) Syntaxin 5 Is Required for the Formation and Clearance of Protein Inclusions during Proteostatic Stress. Cell Reports 28:8, pages 2096-2110.e8.
Crossref
Eugenia M. ClericoWenli MengAlexandra PozhidaevaKarishma BhasneConstantine PetridisLila M. Gierasch. (2019) Hsp70 molecular chaperones: multifunctional allosteric holding and unfolding machines. Biochemical Journal 476:11, pages 1653-1677.
Crossref
Ali Chaari. (2019) Molecular chaperones biochemistry and role in neurodegenerative diseases. International Journal of Biological Macromolecules 131, pages 396-411.
Crossref
Kajsa Fritzell, Li-Di Xu, Magdalena Otrocka, Claes Andréasson & Marie Öhman. (2019) Sensitive ADAR editing reporter in cancer cells enables high-throughput screening of small molecule libraries. Nucleic Acids Research 47:4, pages e22-e22.
Crossref
Unekwu M. Yakubu & Kevin A. Morano. (2018) Roles of the nucleotide exchange factor and chaperone Hsp110 in cellular proteostasis and diseases of protein misfolding. Biological Chemistry 399:10, pages 1215-1221.
Crossref
Amber Tariq, JiaBei Lin, Megan M Noll, Mariana P Torrente, Korrie L Mack, Oscar Hernandez Murillo, Meredith E Jackrel & James Shorter. (2018) Potentiating Hsp104 activity via phosphomimetic mutations in the middle domain. FEMS Yeast Research 18:5.
Crossref
Debasish Kumar Ghosh, Ajit Roy & Akash Ranjan. (2018) The ATP ase VCP /p97 functions as a disaggregase against toxic Huntingtin‐exon1 aggregates . FEBS Letters 592:16, pages 2680-2692.
Crossref
Tamara Suhm, Jayasankar Mohanakrishnan Kaimal, Hannah Dawitz, Carlotta Peselj, Anna E. Masser, Sarah Hanzén, Matevž Ambrožič, Agata Smialowska, Markus L. Björck, Peter Brzezinski, Thomas Nyström, Sabrina Büttner, Claes Andréasson & Martin Ott. (2018) Mitochondrial Translation Efficiency Controls Cytoplasmic Protein Homeostasis. Cell Metabolism 27:6, pages 1309-1322.e6.
Crossref
Nadinath B. Nillegoda, Anne S. Wentink & Bernd Bukau. (2018) Protein Disaggregation in Multicellular Organisms. Trends in Biochemical Sciences 43:4, pages 285-300.
Crossref
G. Michael Preston, Christopher J. Guerriero, Meredith B. Metzger, Susan Michaelis & Jeffrey L. Brodsky. (2018) Substrate Insolubility Dictates Hsp104-Dependent Endoplasmic-Reticulum-Associated Degradation. Molecular Cell 70:2, pages 242-253.e6.
Crossref
Nathan M. Rowarth & Thomas H. MacRae. (2018) ArHsp40 and ArHsp40-2 contribute to stress tolerance and longevity in Artemia franciscana , but only ArHsp40 influences diapause entry . Journal of Experimental Biology.
Crossref
Ganapathi Kandasamy & Claes Andréasson. (2018) Hsp70-Hsp110 chaperones deliver ubiquitin dependent and independent substrates to the 26S proteasome for proteolysis. Journal of Cell Science.
Crossref
Naveen K. C. Gowda, Jayasankar M. Kaimal, Roman Kityk, Chammiran Daniel, Jobst Liebau, Marie Öhman, Matthias P. Mayer & Claes Andréasson. (2018) Nucleotide exchange factors Fes1 and HspBP1 mimic substrate to release misfolded proteins from Hsp70. Nature Structural & Molecular Biology 25:1, pages 83-89.
Crossref
Axel Mogk, Bernd Bukau & Harm H. Kampinga. (2018) Cellular Handling of Protein Aggregates by Disaggregation Machines. Molecular Cell 69:2, pages 214-226.
Crossref
Lynn Boyd & Katherine M. Sampuda. 2018. Heat Shock Proteins and Stress. Heat Shock Proteins and Stress 3 11 .
Jungsoon LeeNuri SungLythou YeoChangsoo ChangSukyeong LeeFrancis T.F. Tsai. (2017) Structural determinants for protein unfolding and translocation by the Hsp104 protein disaggregase. Bioscience Reports 37:6.
Crossref
Veronica M. Garcia, Nadinath B. Nillegoda, Bernd Bukau & Kevin A. Morano. (2017) Substrate binding by the yeast Hsp110 nucleotide exchange factor and molecular chaperone Sse1 is not obligate for its biological activities. Molecular Biology of the Cell 28:15, pages 2066-2075.
Crossref
Nadinath B Nillegoda, Antonia Stank, Duccio Malinverni, Niels Alberts, Anna Szlachcic, Alessandro Barducci, Paolo De Los Rios, Rebecca C Wade & Bernd Bukau. (2017) Evolution of an intricate J-protein network driving protein disaggregation in eukaryotes. eLife 6.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.