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Molecular and Cellular Biology Volume 32, 2012 - Issue 13
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Article

The Arginine Attenuator Peptide Interferes with the Ribosome Peptidyl Transferase Center

Jiajie WeiDepartment of Biology, Texas A&M University, College Station, Texas, USA
,
Cheng WuDepartment of Biology, Texas A&M University, College Station, Texas, USA
&
Matthew S. SachsDepartment of Biology, Texas A&M University, College Station, Texas, USACorrespondence[email protected]
Pages 2396-2406 | Received 28 Jan 2012, Accepted 09 Apr 2012, Published online: 20 Mar 2023

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Hung-Hsi Chen & Woan-Yuh Tarn. (2019) uORF-mediated translational control: recently elucidated mechanisms and implications in cancer. RNA Biology 16:10, pages 1327-1338.
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Cláudia Onofre, Filipa Tomé, Cristina Barbosa, Ana Luísa Silva & Luísa Romão. (2015) Expression of Human Hemojuvelin (HJV) Is Tightly Regulated by Two Upstream Open Reading Frames in HJV mRNA That Respond to Iron Overload in Hepatic Cells. Molecular and Cellular Biology 35:8, pages 1376-1389.
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Marco Chiabudini, Arlette Tais, Ying Zhang, Sachiko Hayashi, Tina Wölfle, Edith Fitzke & Sabine Rospert. (2014) Release Factor eRF3 Mediates Premature Translation Termination on Polylysine-Stalled Ribosomes in . Molecular and Cellular Biology 34:21, pages 4062-4076.
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Articles from other publishers (36)

Shinobu Chiba, Keigo Fujiwara, Yuhei Chadani & Hideki Taguchi. (2023) Nascent chain-mediated translation regulation in bacteria: translation arrest and intrinsic ribosome destabilization. The Journal of Biochemistry 173:4, pages 227-236.
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Ty A. Bottorff, Heungwon Park, Adam P. Geballe & Arvind Rasi Subramaniam. (2022) Translational buffering by ribosome stalling in upstream open reading frames. PLOS Genetics 18:10, pages e1010460.
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Guang Li, Gilbert Eriani, En-Duo Wang & Xiao-Long Zhou. (2021) Distinct pathogenic mechanisms of various RARS1 mutations in Pelizaeus-Merzbacher-like disease. Science China Life Sciences 64:10, pages 1645-1660.
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Anne-Xander van der Stel, Emily R. Gordon, Arnab Sengupta, Allyson K. Martínez, Dorota Klepacki, Thomas N. Perry, Alba Herrero del Valle, Nora Vázquez-Laslop, Matthew S. Sachs, Luis R. Cruz-Vera & C. Axel Innis. (2021) Structural basis for the tryptophan sensitivity of TnaC-mediated ribosome stalling. Nature Communications 12:1.
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Chhaminder Kaur & Swati Patankar. (2021) The role of upstream open reading frames in translation regulation in the apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii . Parasitology 148:11, pages 1277-1287.
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Anthony Gaba, Hongyun Wang, Trinisia Fortune & Xiaohui Qu. (2021) Smart-ORF: a single-molecule method for accessing ribosome dynamics in both upstream and main open reading frames. Nucleic Acids Research 49:5, pages e26-e26.
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Thomas E. DeverIvaylo P. IvanovMatthew S. Sachs. (2020) Conserved Upstream Open Reading Frame Nascent Peptides That Control Translation. Annual Review of Genetics 54:1, pages 237-264.
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Fujun Zhou, Hongen Zhang, Shardul D. Kulkarni, Jon R. Lorsch & Alan G. Hinnebusch. (2020) eIF1 discriminates against suboptimal initiation sites to prevent excessive uORF translation genome-wide. RNA 26:4, pages 419-438.
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Seidai Takamatsu, Yubun Ohashi, Noriyuki Onoue, Yoko Tajima, Tomoya Imamichi, Shinya Yonezawa, Kyoko Morimoto, Hitoshi Onouchi, Yui Yamashita & Satoshi Naito. (2020) Reverse genetics-based biochemical studies of the ribosomal exit tunnel constriction region in eukaryotic ribosome stalling: spatial allocation of the regulatory nascent peptide at the constriction. Nucleic Acids Research 48:4, pages 1985-1999.
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Shuo Wang, Chuanbin Mao & Shanrong Liu. (2019) Peptides encoded by noncoding genes: challenges and perspectives. Signal Transduction and Targeted Therapy 4:1.
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Wenfei Li, Fred R. Ward, Kim F. McClure, Stacey Tsai-Lan Chang, Elizabeth Montabana, Spiros Liras, Robert G. Dullea & Jamie H. D. Cate. (2019) Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nature Structural & Molecular Biology 26:6, pages 501-509.
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Nicole E. Gregorio, Max Z. Levine & Javin P. Oza. (2019) A User’s Guide to Cell-Free Protein Synthesis. Methods and Protocols 2:1, pages 24.
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Cheng Wu, Ananya Dasgupta, Lunda Shen, Deborah Bell-Pedersen & Matthew S. Sachs. (2018) The cell free protein synthesis system from the model filamentous fungus Neurospora crassa. Methods 137, pages 11-19.
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Anton A. Komar. (2018) Unraveling co-translational protein folding: Concepts and methods. Methods 137, pages 71-81.
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Claudio A.P. Joazeiro. (2017) Ribosomal Stalling During Translation: Providing Substrates for Ribosome-Associated Protein Quality Control. Annual Review of Cell and Developmental Biology 33:1, pages 343-368.
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Noriya Hayashi, Shun Sasaki, Hiro Takahashi, Yui Yamashita, Satoshi Naito & Hitoshi Onouchi. (2017) Identification of Arabidopsis thaliana upstream open reading frames encoding peptide sequences that cause ribosomal arrest. Nucleic Acids Research 45:15, pages 8844-8858.
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Ivaylo P. Ivanov, Jiajie Wei, Stephen Z. Caster, Kristina M. Smith, Audrey M. Michel, Ying Zhang, Andrew E. Firth, Michael Freitag, Jay C. Dunlap, Deborah Bell-Pedersen, John F. Atkins & Matthew S. Sachs. (2017) Translation Initiation from Conserved Non-AUG Codons Provides Additional Layers of Regulation and Coding Capacity. mBio 8:3.
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Yui Yamashita, Seidai Takamatsu, Michael Glasbrenner, Thomas Becker, Satoshi Naito & Roland Beckmann. (2017) Sucrose sensing through nascent peptide-meditated ribosome stalling at the stop codon of Arabidopsis bZIP11 uORF2 . FEBS Letters 591:9, pages 1266-1277.
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Sara K. Young & Ronald C. Wek. (2016) Upstream Open Reading Frames Differentially Regulate Gene-specific Translation in the Integrated Stress Response. Journal of Biological Chemistry 291:33, pages 16927-16935.
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Alan G. HinnebuschIvaylo P. IvanovNahum Sonenberg. (2016) Translational control by 5′-untranslated regions of eukaryotic mRNAs. Science 352:6292, pages 1413-1416.
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Thomas E Dever, Terri Goss Kinzy & Graham D Pavitt. (2016) Mechanism and Regulation of Protein Synthesis in Saccharomyces cerevisiae . Genetics 203:1, pages 65-107.
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Daniel N Wilson, Stefan Arenz & Roland Beckmann. (2016) Translation regulation via nascent polypeptide-mediated ribosome stalling. Current Opinion in Structural Biology 37, pages 123-133.
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Yui YAMASHITA, Hitoshi ONOUCHI & Satoshi NAITO. (2016) . Kagaku To Seibutsu KAGAKU TO SEIBUTSU 54:3, pages 191-197.
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Renana Sabi & Tamir Tuller. (2015) A comparative genomics study on the effect of individual amino acids on ribosome stalling. BMC Genomics 16:S10.
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Ying Zhang & Matthew S Sachs. (2015) Control of mRNA Stability in Fungi by NMD, EJC and CBC Factors Through 3′UTR Introns. Genetics 200:4, pages 1133-1148.
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Martina M. Yordanova, Cheng Wu, Dmitry E. Andreev, Matthew S. Sachs & John F. Atkins. (2015) A Nascent Peptide Signal Responsive to Endogenous Levels of Polyamines Acts to Stimulate Regulatory Frameshifting on Antizyme mRNA. Journal of Biological Chemistry 290:29, pages 17863-17878.
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Isao Ebina, Mariko Takemoto-Tsutsumi, Shun Watanabe, Hiroaki Koyama, Yayoi Endo, Kaori Kimata, Takuya Igarashi, Karin Murakami, Rin Kudo, Arisa Ohsumi, Abdul Latif Noh, Hiro Takahashi, Satoshi Naito & Hitoshi Onouchi. (2015) Identification of novel Arabidopsis thaliana upstream open reading frames that control expression of the main coding sequences in a peptide sequence-dependent manner . Nucleic Acids Research 43:3, pages 1562-1576.
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Naoko Uchiyama-Kadokura, Karin Murakami, Mariko Takemoto, Naoto Koyanagi, Katsunori Murota, Satoshi Naito & Hitoshi Onouchi. (2014) Polyamine-Responsive Ribosomal Arrest at the Stop Codon of an Upstream Open Reading Frame of the AdoMetDC1 Gene Triggers Nonsense-Mediated mRNA Decay in Arabidopsis thaliana. Plant and Cell Physiology 55:9, pages 1556-1567.
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Cristina Barbosa & Luísa Romão. (2014) Translation of the human erythropoietin transcript is regulated by an upstream open reading frame in response to hypoxia. RNA 20:5, pages 594-608.
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Yui Yamashita, Yoshitomo Kadokura, Naoyuki Sotta, Toru Fujiwara, Ichigaku Takigawa, Akiko Satake, Hitoshi Onouchi & Satoshi Naito. (2014) Ribosomes in a Stacked Array. Journal of Biological Chemistry 289:18, pages 12693-12704.
Crossref
Koreaki Ito. 2014. Regulatory Nascent Polypeptides. Regulatory Nascent Polypeptides 135 148 .
Koreaki Ito & Shinobu Chiba. 2014. Regulatory Nascent Polypeptides. Regulatory Nascent Polypeptides 3 20 .
Bijoyita Roy & Allan Jacobson. (2013) The intimate relationships of mRNA decay and translation. Trends in Genetics 29:12, pages 691-699.
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Koreaki ItoShinobu Chiba. (2013) Arrest Peptides: Cis -Acting Modulators of Translation . Annual Review of Biochemistry 82:1, pages 171-202.
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Jiajie Wei, Ying Zhang, Ivaylo P. Ivanov & Matthew S. Sachs. (2013) The Stringency of Start Codon Selection in the Filamentous Fungus Neurospora crassa. Journal of Biological Chemistry 288:13, pages 9549-9562.
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Shinobu Chiba & Koreaki Ito. (2012) Multisite Ribosomal Stalling: A Unique Mode of Regulatory Nascent Chain Action Revealed for MifM. Molecular Cell 47:6, pages 863-872.
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