Advanced search
Publication Cover
Molecular and Cellular Biology Volume 37, 2017 - Issue 18
Submit an article Journal homepage
421
Views
25
CrossRef citations to date
0
Altmetric
Research Article

The N-Terminal Part of the Dishevelled DEP Domain Is Required for Wnt/β-Catenin Signaling in Mammalian Cells

Petra Paclíkováa Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic
,
Ondřej Bernatíka Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic
,
Tomasz Witold Radaszkiewicza Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic
&
Vítězslav Bryjaa Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic;b Institute of Biophysics, The Czech Academy of Sciences, Brno, Czech RepublicCorrespondence[email protected]
Article: e00145-17 | Received 29 Mar 2017, Accepted 15 Jun 2017, Published online: 17 Mar 2023

Citations (25)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Vítězslav Bryja, Igor Červenka & Lukáš Čajánek. (2017) The connections of Wnt pathway components with cell cycle and centrosome: side effects or a hidden logic?. Critical Reviews in Biochemistry and Molecular Biology 52:6, pages 614-637.
Read now

Articles from other publishers (24)

Do Hyun Kim, Alexandra M. Binder, Hua Zhou & Su Yon Jung. (2023) DNA methylation patterns associated with breast cancer prognosis that are specific to tumor subtype and menopausal status. Frontiers in Genetics 14.
Crossref
Francesco L. Falginella, Marek Kravec, Martina Drabinová, Petra Paclíková, Vítĕzslav Bryja & Robert Vácha. (2022) Binding of DEP domain to phospholipid membranes: More than just electrostatics. Biochimica et Biophysica Acta (BBA) - Biomembranes 1864:10, pages 183983.
Crossref
Geetha Priya Boligala, Mingxiao V. Yang, Jenna C. van Wunnik & Kevin Pruitt. (2022) Nuclear Dishevelled: An enigmatic role in governing cell fate and Wnt signaling. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1869:10, pages 119305.
Crossref
Jacob P. Mahoney, Elise S. Bruguera, Mansi VasishthaLauren B. KillingsworthSaw KyawWilliam I. Weis. (2022) PI(4,5)P 2 -stimulated positive feedback drives the recruitment of Dishevelled to Frizzled in Wnt–β-catenin signaling . Science Signaling 15:748.
Crossref
Qiaoni Shi & Ye-Guang Chen. (2021) Regulation of Dishevelled protein activity and stability by post-translational modifications and autophagy. Trends in Biochemical Sciences 46:12, pages 1003-1016.
Crossref
Tomasz Radaszkiewicz, Michaela Nosková, Kristína Gömöryová, Olga Vondálová Blanářová, Katarzyna Anna Radaszkiewicz, Markéta Picková, Ráchel Víchová, Tomáš Gybeľ, Karol Kaiser, Lucia Demková, Lucia Kučerová, Tomáš Bárta, David Potěšil, Zbyněk Zdráhal, Karel Souček & Vítězslav Bryja. (2021) RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy. eLife 10.
Crossref
Wei Hu, Mingxu Li, Junyi Wu, Hong Chen, Ting  Zhao, Chunjie Zhang & Zhong Wang. (2021) Inhibition of Dishevelled‑2 suppresses the biological behavior of pancreatic cancer by downregulating Wnt/β‑catenin signaling. Oncology Letters 22:5.
Crossref
Ondrej Bernatik, Petra Paclikova, Anna Kotrbova, Vitezslav Bryja & Lukas Cajanek. (2021) Primary Cilia Formation Does Not Rely on WNT/β-Catenin Signaling. Frontiers in Cell and Developmental Biology 9.
Crossref
Miroslav Jurásek, Jitender Kumar, Petra Paclíková, Alka Kumari, Konstantinos Tripsianes, Vítězslav Bryja & Robert Vácha. (2021) Phosphorylation-induced changes in the PDZ domain of Dishevelled 3. Scientific Reports 11:1.
Crossref
Tomasz Radaszkiewicz & Vítězslav Bryja. (2020) Protease associated domain of RNF43 is not necessary for the suppression of Wnt/β-catenin signaling in human cells. Cell Communication and Signaling 18:1.
Crossref
De-Li Shi. (2020) Decoding Dishevelled-Mediated Wnt Signaling in Vertebrate Early Development. Frontiers in Cell and Developmental Biology 8.
Crossref
Katarzyna Anna Radaszkiewicz, Deborah Beckerová, Lucie Woloszczuková, Tomasz Witold Radaszkiewicz, Petra Lesáková, Olga Vondálová Blanářová, Lukáš Kubala, Petr Humpolíček & Jiří Pachernik. (2020) 12-O-Tetradecanoylphorbol-13-acetate increases cardiomyogenesis through PKC/ERK signaling. Scientific Reports 10:1.
Crossref
Ondrej Bernatik, Petra Paclikova, Ranjani Sri Ganji & Vitezslav Bryja. (2020) Activity of Smurf2 Ubiquitin Ligase Is Regulated by the Wnt Pathway Protein Dishevelled. Cells 9:5, pages 1147.
Crossref
Marie-Claire Kratzer, Sarah F. S. Becker, Anita Grund, Anne Merks, Jakub Harnoš, Vítězslav Bryja, Klaudia Giehl, Jubin Kashef & Annette Borchers. (2020) The Rho guanine nucleotide exchange factor Trio is required for neural crest cell migration and interacts with Dishevelled. Development.
Crossref
Kateřina Hanáková, Ondřej Bernatík, Marek Kravec, Miroslav Micka, Jitender Kumar, Jakub Harnoš, Petra Ovesná, Petra Paclíková, Matěj Rádsetoulal, David Potěšil, Konstantinos Tripsianes, Lukáš Čajánek, Zbyněk Zdráhal & Vítězslav Bryja. (2019) Comparative phosphorylation map of Dishevelled 3 links phospho-signatures to biological outputs. Cell Communication and Signaling 17:1.
Crossref
Monica Sharma, Deborah Molehin, Isabel Castro-Piedras, Edgar G. Martinez & Kevin Pruitt. (2019) Acetylation of conserved DVL-1 lysines regulates its nuclear translocation and binding to gene promoters in triple-negative breast cancer. Scientific Reports 9:1.
Crossref
Sébastien Dupasquier, Philippe Blache, Laurence Picque Lasorsa, Han Zhao, Jean-Daniel Abraham, Jody J. Haigh, Marc Ychou & Corinne Prévostel. (2019) Modulating PKCα Activity to Target Wnt/β-Catenin Signaling in Colon Cancer. Cancers 11:5, pages 693.
Crossref
Jakub Harnoš, Maria Consuelo Alonso Cañizal, Miroslav Jurásek, Jitender Kumar, Cornelia Holler, Alexandra Schambony, Kateřina Hanáková, Ondřej Bernatík, Zbyněk Zdráhal, Kristína Gömöryová, Tomáš Gybeľ, Tomasz Witold Radaszkiewicz, Marek Kravec, Lukáš Trantírek, Jan Ryneš, Zankruti Dave, Ana Iris Fernández-Llamazares, Robert Vácha, Konstantinos Tripsianes, Carsten Hoffmann & Vítězslav Bryja. (2019) Dishevelled-3 conformation dynamics analyzed by FRET-based biosensors reveals a key role of casein kinase 1. Nature Communications 10:1.
Crossref
Dipak N Patil, Erumbi S Rangarajan, Scott J Novick, Bruce D Pascal, Douglas J Kojetin, Patrick R Griffin, Tina Izard & Kirill A Martemyanov. (2018) Structural organization of a major neuronal G protein regulator, the RGS7-Gβ5-R7BP complex. eLife 7.
Crossref
Jana Valnohova, Maria Kowalski-Jahn, Roger K. Sunahara & Gunnar Schulte. (2018) Functional dissection of the N-terminal extracellular domains of Frizzled 6 reveals their roles for receptor localization and Dishevelled recruitment. Journal of Biological Chemistry 293:46, pages 17875-17887.
Crossref
Katerina Strakova, Maria Kowalski-Jahn, Tomas Gybel, Jana Valnohova, Vishnu M. Dhople, Jakub Harnos, Ondrej Bernatik, Ranjani Sri Ganji, Zbynek Zdrahal, Jan Mulder, Cecilia Lindskog, Vitezslav Bryja & Gunnar Schulte. (2018) Dishevelled enables casein kinase 1–mediated phosphorylation of Frizzled 6 required for cell membrane localization. Journal of Biological Chemistry 293:48, pages 18477-18493.
Crossref
Koji Kikuchi, Akira Nakamura, Masaki Arata, Dongbo Shi, Mami Nakagawa, Tsubasa Tanaka, Tadashi Uemura, Toshihiko Fujimori, Akira Kikuchi, Akiyoshi Uezu, Yasuhisa Sakamoto & Hiroyuki Nakanishi. (2018) Map7/7D1 and Dvl form a feedback loop that facilitates microtubule remodeling and Wnt5a signaling. EMBO reports 19:7.
Crossref
Yoonmi Lee, Nam Hee Kim, Eunae Sandra Cho, Ji Hye Yang, Yong Hoon Cha, Hee Eun Kang, Jun Seop Yun, Sue Bean Cho, Seon-Hyeong Lee, Petra Paclikova, Tomasz W. Radaszkiewicz, Vitezslav Bryja, Chi Gu Kang, Young Soo Yuk, So Young Cha, Soo-Youl Kim, Hyun Sil Kim & Jong In Yook. (2018) Dishevelled has a YAP nuclear export function in a tumor suppressor context-dependent manner. Nature Communications 9:1.
Crossref
Melissa Gammons & Mariann Bienz. (2018) Multiprotein complexes governing Wnt signal transduction. Current Opinion in Cell Biology 51, pages 42-49.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.