33
Views
34
CrossRef citations to date
0
Altmetric
Article

The Stress Response Mediator ATF3 Represses Androgen Signaling by Binding the Androgen Receptor

, , , , , , , & show all
Pages 3190-3202 | Received 02 Feb 2012, Accepted 22 May 2012, Published online: 20 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Ziyan Wang & Chunhong Yan. (2016) Emerging roles of ATF3 in the suppression of prostate cancer. Molecular & Cellular Oncology 3:1.
Read now

Articles from other publishers (33)

少霞 王. (2023) Research Progress of Activating Transcription Factor 3 in Tumors. Advances in Clinical Medicine 13:03, pages 2918-2925.
Crossref
Attila Meszaros, Junaid Ahmed, Giorgio Russo, Peter Tompa & Tamas Lazar. (2022) The evolution and polymorphism of mono-amino acid repeats in androgen receptor and their regulatory role in health and disease. Frontiers in Medicine 9.
Crossref
Pavlína Šimečková, Kateřina Pěnčíková, Ondrej Kováč, Josef Slavík, Martina Pařenicová, Jan Vondráček & Miroslav Machala. (2022) In vitro profiling of toxic effects of environmental polycyclic aromatic hydrocarbons on nuclear receptor signaling, disruption of endogenous metabolism and induction of cellular stress. Science of The Total Environment 815, pages 151967.
Crossref
Jing Chen, Esther A. Zaal, Celia R. Berkers, Rob Ruijtenbeek, Johan Garssen & Frank A. Redegeld. (2021) Omega-3 Fatty Acids DHA and EPA Reduce Bortezomib Resistance in Multiple Myeloma Cells by Promoting Glutathione Degradation. Cells 10:9, pages 2287.
Crossref
Xingyao Li, Daniel Gracilla, Lun Cai, Mingyi Zhang, Xiaolin Yu, Xiaoguang Chen, Junran Zhang, Xiaochun Long, Han-Fei Ding & Chunhong Yan. (2021) ATF3 promotes the serine synthesis pathway and tumor growth under dietary serine restriction. Cell Reports 36:12, pages 109706.
Crossref
Zhilong Wang, Yang Liu, Jingyu Liu, Na Kong, Yue Jiang, Ruiwei Jiang, Xin Zhen, Jidong Zhou, Chaojun Li, Haixiang Sun & Guijun Yan. (2021) ATF3 deficiency impairs the proliferative–secretory phase transition and decidualization in RIF patients. Cell Death & Disease 12:4.
Crossref
Chin-Hong Chang, Ying-Shuang Chang & Yu-Lin Hsieh. (2021) Transient receptor potential vanilloid subtype 1 depletion mediates mechanical allodynia through cellular signal alterations in small-fiber neuropathy. PAIN Reports 6:1, pages e922.
Crossref
Hui-Chen Ku & Ching-Feng Cheng. (2020) Master Regulator Activating Transcription Factor 3 (ATF3) in Metabolic Homeostasis and Cancer. Frontiers in Endocrinology 11.
Crossref
Jing Jin, Nina Xue, Yuan Liu, Rong Fu, Mingjin Wang, Ming Ji, Fangfang Lai, Jinping Hu, Xiaojian Wang, Qiong Xiao, Xiaoying Zhang, Dali Yin, Liping Bai, Xiaoguang Chen & Shuan Rao. (2020) A novel S1P1 modulator IMMH002 ameliorates psoriasis in multiple animal models. Acta Pharmaceutica Sinica B 10:2, pages 276-288.
Crossref
Yanhui Wang, Xiaoqing Chi & Dazhi Meng. (2019) The Application of Network Structure Aanalysis in the Study of Disease Mechanisms. The Application of Network Structure Aanalysis in the Study of Disease Mechanisms.
Seonung Lim, Wonwoo Lee, Doo Lee, In-Jeong Nam, Nayoung Yun, Yoonseon Jeong, Taewoong Rho & Sunyoung Kim. (2018) Botanical Formulation HX109 Ameliorates TP-Induced Benign Prostate Hyperplasia in Rat Model and Inhibits Androgen Receptor Signaling by Upregulating Ca2+/CaMKKβ and ATF3 in LNCaP Cells. Nutrients 10:12, pages 1946.
Crossref
Seung-Whan Kim, Hyun-Woo Suh, Bo-Kyung Yoo, Kisang Kwon, Kweon Yu, Ji-Young Choi & O-Yu Kwon. (2018) Larval hemolymph of rhinoceros beetle, Allomyrina dichotoma , enhances insulin secretion through ATF3 gene expression in INS-1 pancreatic β-cells . Zeitschrift für Naturforschung C 73:9-10, pages 391-396.
Crossref
Shoko Matsushita, Kentaro Suzuki, Aki Murashima, Daiki Kajioka, Alvin Resultay Acebedo, Shinichi Miyagawa, Ryuma Haraguchi, Yukiko Ogino & Gen Yamada. (2018) Regulation of masculinization: androgen signalling for external genitalia development. Nature Reviews Urology 15:6, pages 358-368.
Crossref
Avital Lev, Amriti R. Lulla, Brian C. Ross, Marie D. Ralff, Petr B. Makhov, David T. Dicker & Wafik S. El-Deiry. (2018) ONC201 Targets AR and AR-V7 Signaling, Reduces PSA, and Synergizes with Everolimus in Prostate Cancer. Molecular Cancer Research 16:5, pages 754-766.
Crossref
Jaeseok Han & Randal J. Kaufman. (2017) Physiological/pathological ramifications of transcription factors in the unfolded protein response. Genes & Development 31:14, pages 1417-1438.
Crossref
Wenying Yu, Chenglong Li, Wenda Zhang, Yuanzheng Xia, Shanshan Li, Jia-yuh Lin, Keqin Yu, Mu Liu, Lei Yang, Jianguang Luo, Yijun Chen, Hongbin Sun & Lingyi Kong. (2017) Discovery of an Orally Selective Inhibitor of Signal Transducer and Activator of Transcription 3 Using Advanced Multiple Ligand Simultaneous Docking. Journal of Medicinal Chemistry 60:7, pages 2718-2731.
Crossref
Jonathan Zhao, Xingyao Li, Mingxiong Guo, Jindan Yu & Chunhong Yan. (2016) The common stress responsive transcription factor ATF3 binds genomic sites enriched with p300 and H3K27ac for transcriptional regulation. BMC Genomics 17:1.
Crossref
Z Wang, J Kim, Y Teng, H-F Ding, J Zhang, T Hai, J K Cowell & C Yan. (2015) Loss of ATF3 promotes hormone-induced prostate carcinogenesis and the emergence of CK5+CK8+ epithelial cells. Oncogene 35:27, pages 3555-3564.
Crossref
Thirupandiyur S. Udayakumar, Radka Stoyanova, Mohammed M. Shareef, Zhaomei Mu, Sakhi Philip, Kerry L. Burnstein & Alan Pollack. (2016) Edelfosine Promotes Apoptosis in Androgen-Deprived Prostate Tumors by Increasing ATF3 and Inhibiting Androgen Receptor Activity. Molecular Cancer Therapeutics 15:6, pages 1353-1363.
Crossref
Hongmei Cui, Xingyao Li, Chunhua Han, Qi-En Wang, Hongbo Wang, Han-Fei Ding, Junran Zhang & Chunhong Yan. (2016) The Stress-responsive Gene ATF3 Mediates Dichotomous UV Responses by Regulating the Tip60 and p53 Proteins. Journal of Biological Chemistry 291:20, pages 10847-10857.
Crossref
Fabiola Cecchi, Chih-Jian Lih, Young H. Lee, William Walsh, Daniel C. Rabe, Paul M. Williams & Donald P. Bottaro. (2015) Expression array analysis of the hepatocyte growth factor invasive program. Clinical & Experimental Metastasis 32:7, pages 659-676.
Crossref
Z Wang, D Xu, H-F Ding, J Kim, J Zhang, T Hai & C Yan. (2014) Loss of ATF3 promotes Akt activation and prostate cancer development in a Pten knockout mouse model. Oncogene 34:38, pages 4975-4984.
Crossref
Ya-di Geng, Chao Zhang, Ya-min Shi, Yuan-zheng Xia, Chao Guo, Lei Yang & Ling-yi Kong. (2015) Icariside II-induced mitochondrion and lysosome mediated apoptosis is counterbalanced by an autophagic salvage response in hepatoblastoma. Cancer Letters 366:1, pages 19-31.
Crossref
Hongmei Cui, Mingxiong Guo, Dong Xu, Zhi-Chun Ding, Gang Zhou, Han-Fei Ding, Junran Zhang, Yi Tang & Chunhong Yan. (2015) The stress-responsive gene ATF3 regulates the histone acetyltransferase Tip60. Nature Communications 6:1.
Crossref
Zhen-Feng Hao, You-Ming Su, Cong-min Wang & Rong-Ya Yang. (2014) Activating transcription factor 3 interferes with p21 activation in histone deacetylase inhibitor-induced growth inhibition of epidermoid carcinoma cells. Tumor Biology 36:3, pages 1471-1476.
Crossref
Ya-di Geng, Lei Yang, Chao Zhang & Ling-yi Kong. (2014) Blockade of epidermal growth factor receptor/mammalian target of rapamycin pathway by Icariside II results in reduced cell proliferation of osteosarcoma cells. Food and Chemical Toxicology 73, pages 7-16.
Crossref
Mounia Tannour-Louet, Shuo Han, Jean-Francois Louet, Bin Zhang, Karina Romero, Josephine Addai, Aysegul Sahin, Sau Wai Cheung & Dolores J Lamb. (2014) Increased gene copy number of VAMP7 disrupts human male urogenital development through altered estrogen action. Nature Medicine 20:7, pages 715-724.
Crossref
Jing Jin, Jinping Hu, Wanqi Zhou, Xiaojian Wang, Qiong Xiao, Nina Xue, Dali Yin & Xiaoguang Chen. (2014) Development of a selective S1P1 receptor agonist, Syl930, as a potential therapeutic agent for autoimmune encephalitis. Biochemical Pharmacology 90:1, pages 50-61.
Crossref
Saisai Wei, Hongbo Wang, Chunwan Lu, Sarah Malmut, Jianqiao Zhang, Shumei Ren, Guohua Yu, Wei Wang, Dale D. Tang & Chunhong Yan. (2014) The Activating Transcription Factor 3 Protein Suppresses the Oncogenic Function of Mutant p53 Proteins. Journal of Biological Chemistry 289:13, pages 8947-8959.
Crossref
Jae-kyung Park, Hoon Jang, SeongSoo Hwang, Eun-Jung Kim, Dong-Ern Kim, Keon-Bong Oh, Dae-Jin Kwon, Jeong-Tae Koh, Kumi Kimura, Hiroshi Inoue, Won-Gu Jang & Jeong-Woong Lee. (2014) ER stress-inducible ATF3 suppresses BMP2-induced ALP expression and activation in MC3T3-E1 cells. Biochemical and Biophysical Research Communications 443:1, pages 333-338.
Crossref
Zhen-Feng Hao, Jun-Hong Ao, Jie Zhang, You-Ming Su & Rong-Ya Yang. (2013) ATF3 Activates Stat3 Phosphorylation through Inhibition of p53 Expression in Skin Cancer Cells. Asian Pacific Journal of Cancer Prevention 14:12, pages 7439-7444.
Crossref
Chunwan Lu, Di Liu, Jing Jin, Hemantkumar Deokar, Yi Zhang, John K. Buolamwini, Xiaoming Yu, Chunhong Yan & Xiaoguang Chen. (2013) Inhibition of gastric tumor growth by a novel Hsp90 inhibitor. Biochemical Pharmacology 85:9, pages 1246-1256.
Crossref
Chiung-Min Wang & Wei-Hsiung Yang. (2013) Loss of SUMOylation on ATF3 Inhibits Proliferation of Prostate Cancer Cells by Modulating CCND1/2 Activity. International Journal of Molecular Sciences 14:4, pages 8367-8380.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.