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Molecular and Cellular Biology Volume 34, 2014 - Issue 18
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Article

Cell Activation-Induced Phosphoinositide 3-Kinase Alpha/Beta Dimerization Regulates PTEN Activity

Vicente Pérez-GarcíaDepartment of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Cantoblanco, Madrid, Spain
,
Javier Redondo-MuñozDepartment of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Cantoblanco, Madrid, Spain
,
Amit KumarDepartment of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Cantoblanco, Madrid, Spain
&
Ana C. CarreraDepartment of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Cantoblanco, Madrid, SpainCorrespondence[email protected]
Pages 3359-3373 | Received 03 Feb 2014, Accepted 18 Jun 2014, Published online: 20 Mar 2023

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Claire Conche & Karsten Sauer. (2014) Uncovering the PI3Ksome: Phosphoinositide 3-Kinases and Counteracting PTEN Form a Signaling Complex with Intrinsic Regulatory Properties. Molecular and Cellular Biology 34:18, pages 3356-3358.
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Articles from other publishers (10)

Esteban Salazar-Petres, Daniela Pereira-Carvalho, Jorge Lopez-Tello & Amanda N. Sferruzzi-Perri. (2023) Maternal and Intrauterine Influences on Feto-Placental Growth Are Accompanied by Sexually Dimorphic Changes in Placental Mitochondrial Respiration, and Metabolic Signalling Pathways. Cells 12:5, pages 797.
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Jorge Lopez-Tello, Esteban Salazar-Petres, Liam Webb, Abigail L. Fowden & Amanda N. Sferruzzi-Perri. (2022) Ablation of PI3K-p110alpha Impairs Maternal Metabolic Adaptations to Pregnancy. Frontiers in Cell and Developmental Biology 10.
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Ionel Sandovici, Aikaterini Georgopoulou, Vicente Pérez-García, Antonia Hufnagel, Jorge López-Tello, Brian Y.H. Lam, Samira N. Schiefer, Chelsea Gaudreau, Fátima Santos, Katharina Hoelle, Giles S.H. Yeo, Keith Burling, Moritz Reiterer, Abigail L. Fowden, Graham J. Burton, Cristina M. Branco, Amanda N. Sferruzzi-Perri & Miguel Constância. (2022) The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth. Developmental Cell 57:1, pages 63-79.e8.
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Manuel Olazábal-Morán, Miriam Sánchez-Ortega, Laura Martínez-Muñoz, Carmen Hernández, Manuel S. Rodríguez, Mario Mellado & Ana C. Carrera. (2021) Fluctuations in AKT and PTEN Activity Are Linked by the E3 Ubiquitin Ligase cCBL. Cells 10:11, pages 2803.
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Vicente Perez-Garcia, Georgia Lea, Pablo Lopez-Jimenez, Hanneke Okkenhaug, Graham J Burton, Ashley Moffett, Margherita Y Turco & Myriam Hemberger. (2021) BAP1/ASXL complex modulation regulates epithelial-mesenchymal transition during trophoblast differentiation and invasion. eLife 10.
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Fatemeh Mazloumi Gavgani, Thomas Karlsson, Ingvild L. Tangen, Andrea Papdiné Morovicz, Victoria Smith Arnesen, Diana C. Turcu, Sandra Ninzima, Katharina Spang, Camilla Krakstad, Julie Guillermet-Guibert & Aurélia E. Lewis. (2021) Nuclear upregulation of class I phosphoinositide 3-kinase p110β correlates with high 47S rRNA levels in cancer cells. Journal of Cell Science 134:3.
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Jesús Vallejo-Díaz, Monica Chagoyen, Manuel Olazabal-Morán, Ana González-García & Ana Clara Carrera. (2019) The Opposing Roles of PIK3R1/p85α and PIK3R2/p85β in Cancer. Trends in Cancer 5:4, pages 233-244.
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Sebastián A. Riquelme, Benjamin D. Hopkins, Andrew L. Wolfe, Emily DiMango, Kipyegon Kitur, Ramon Parsons & Alice Prince. (2017) Cystic Fibrosis Transmembrane Conductance Regulator Attaches Tumor Suppressor PTEN to the Membrane and Promotes Anti Pseudomonas aeruginosa Immunity. Immunity 47:6, pages 1169-1181.e7.
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Thomas Karlsson, Camilla Krakstad, Ingvild Løberg Tangen, Erling A. Hoivik, Pamela M. Pollock, Helga B. Salvesen & Aurélia E. Lewis. (2016) Endometrial cancer cells exhibit high expression of p110β and its selective inhibition induces variable responses on PI3K signaling, cell survival and proliferation. Oncotarget 8:3, pages 3881-3894.
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Jaclyn LoPiccolo, Seung Joong Kim, Yi Shi, Bin Wu, Haiyan Wu, Brian T. Chait, Robert H. Singer, Andrej Sali, Michael Brenowitz, Anne R. Bresnick & Jonathan M. Backer. (2015) Assembly and Molecular Architecture of the Phosphoinositide 3-Kinase p85α Homodimer. Journal of Biological Chemistry 290:51, pages 30390-30405.
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