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Julienne J O’Rourke, Rohan Bythell-Douglas, Elyse A Dunn & Andrew J Deans. (2019) ALT control, delete: FANCM as an anti-cancer target in Alternative Lengthening of Telomeres. Nucleus 10:1, pages 221-230.
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Jean-Hugues Guervilly & Pierre Henri Gaillard. (2018) SLX4: multitasking to maintain genome stability. Critical Reviews in Biochemistry and Molecular Biology 53:5, pages 475-514.
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Articles from other publishers (116)
Anna M Rose, Tomas Goncalves, Siobhan Cunniffe, Helene E B Geiller, Thomas Kent, Sam Shepherd, Malitha Ratnaweera, Roderick J O’Sullivan, Richard J Gibbons & David Clynes. (2023)
Induction of the alternative lengthening of telomeres pathway by trapping of proteins on
DNA
. Nucleic Acids Research 51:13, pages 6509-6527.
Crossref
Crossref
Ronan Broderick, Veronica Cherdyntseva, Jadwiga Nieminuszczy, Eleni Dragona, Maria Kyriakaki, Theodora Evmorfopoulou, Sarantis Gagos & Wojciech Niedzwiedz. (2023) Pathway choice in the alternative telomere lengthening in neoplasia is dictated by replication fork processing mediated by EXD2’s nuclease activity. Nature Communications 14:1.
Crossref
Crossref
Rekha Rai, Kevin Biju, Wenqi Sun, Tori Sodeinde, Amer Al-Hiyasat, Jaida Morgan, Xianwen Ye, Xueqing Li, Yong Chen & Sandy Chang. (2023) Homology directed telomere clustering, ultrabright telomere formation and nuclear envelope rupture in cells lacking TRF2B and RAP1. Nature Communications 14:1.
Crossref
Crossref
Frances Karla Kusuma, Aishvaryaa Prabhu, Galen Tieo, Syed Moiz Ahmed, Pushkar Dakle, Wai Khang Yong, Elina Pathak, Vikas Madan, Yan Yi Jiang, Wai Leong Tam, Dennis Kappei, Peter Dröge, H. Phillip Koeffler & Maya Jeitany. (2023) Signalling inhibition by ponatinib disrupts productive alternative lengthening of telomeres (ALT). Nature Communications 14:1.
Crossref
Crossref
Sarah F. Clatterbuck Soper & Paul S. Meltzer. (2023) ATRX/DAXX: Guarding the Genome against the Hazards of ALT. Genes 14:4, pages 790.
Crossref
Crossref
Eric J. Sohn, Julia A. Goralsky, Jerry W. Shay & Jaewon Min. (2023) The Molecular Mechanisms and Therapeutic Prospects of Alternative Lengthening of Telomeres (ALT). Cancers 15:7, pages 1945.
Crossref
Crossref
Ryan P. Barnes, Sanjana A. Thosar & Patricia L. Opresko. (2023) Telomere Fragility and MiDAS: Managing the Gaps at the End of the Road. Genes 14:2, pages 348.
Crossref
Crossref
Mandy L. Ballinger, Swetansu Pattnaik, Piyushkumar A. Mundra, Milita Zaheed, Emma Rath, Peter Priestley, Jonathan Baber, Isabelle Ray-Coquard, Nicholas IsambertSylvain Causeret, Winette T. A. van der Graaf, Ajay Puri, Florence Duffaud, Axel Le CesneBeatrice SeddonCoonoor ChandrasekarJoshua D. Schiffman, Andrew S. Brohl, Paul A. James, Jean-Emmanuel KurtzNicolas Penel, Ola Myklebost, Leonardo A. Meza-Zepeda, Hilda PickettMaya Kansara, Nicola Waddell, Olga Kondrashova, John V. Pearson, Andrew P. BarbourShuai Li, Tuong L. Nguyen, Diane Fatkin, Robert M. Graham, Eleni Giannoulatou, Melissa J. Green, Warren Kaplan, Shyamsundar Ravishankar, Joseph Copty, Joseph E. Powell, Edwin Cuppen, Kristel van EijkJan Veldink, Jin-Hee Ahn, Jeong Eun Kim, R. Lor Randall, Kathy Tucker, Ian Judson, Rajiv Sarin, Thomas Ludwig, Emmanuelle Genin, Jean-Francois Deleuze, Michelle Haber, Glenn Marshall, Murray J. Cairns, Jean-Yves Blay & David M. Thomas. (2023) Heritable defects in telomere and mitotic function selectively predispose to sarcomas. Science 379:6629, pages 253-260.
Crossref
Crossref
Shuo Liu, Zi Wang, Sameer Bikram Shah, Chia-Yu Chang, Michael Ai, Tran Nguyen, Rong Xiang & Xiaohua Wu. (2023) DNA repair protein RAD52 is required for protecting G-quadruplexes in mammalian cells. Journal of Biological Chemistry 299:1, pages 102770.
Crossref
Crossref
Tribhuwan Yadav, Jia-Min Zhang, Jian Ouyang, Wendy Leung, Antoine Simoneau & Lee Zou. (2022) TERRA and RAD51AP1 promote alternative lengthening of telomeres through an R- to D-loop switch. Molecular Cell 82:21, pages 3985-4000.e4.
Crossref
Crossref
Nicole Kaminski, Anne R. Wondisford, Youngho Kwon, Michelle Lee Lynskey, Ragini Bhargava, Jonathan Barroso-González, Laura García-Expósito, Boxue He, Meng Xu, Dattatreya Mellacheruvu, Simon C. Watkins, Mauro Modesti, Kyle M. Miller, Alexey I. Nesvizhskii, Huaiying Zhang, Patrick Sung & Roderick J. O’Sullivan. (2022) RAD51AP1 regulates ALT-HDR through chromatin-directed homeostasis of TERRA. Molecular Cell 82:21, pages 4001-4017.e7.
Crossref
Crossref
Alexandre de Nonneville, Sébastien Salas, François Bertucci, Alexander P Sobinoff, José Adélaïde, Arnaud Guille, Pascal Finetti, Jane R Noble, Dimitri Churikov, Max Chaffanet, Elise Lavit, Hilda A Pickett, Corinne Bouvier, Daniel Birnbaum, Roger R Reddel & Vincent Géli. (2022)
TOP3A
amplification and
ATRX
inactivation are mutually exclusive events in pediatric osteosarcomas using
ALT
. EMBO Molecular Medicine 14:10.
Crossref
Crossref
Chia-Yu Guh, Hong-Jhih Shen, Liv WeiChien Chen, Pei-Chen Chiu, I-Hsin Liao, Chen-Chia Lo, Yunfei Chen, Yu-Hung Hsieh, Ting-Chia Chang, Chien-Ping Yen, Yi-Yun Chen, Tom Wei-Wu Chen, Liuh-Yow Chen, Ching-Shyi Wu, Jean-Marc Egly & Hsueh-Ping Catherine Chu. (2022) XPF activates break-induced telomere synthesis. Nature Communications 13:1.
Crossref
Crossref
Jixuan Gao & Hilda A. Pickett. (2022) Targeting telomeres: advances in telomere maintenance mechanism-specific cancer therapies. Nature Reviews Cancer 22:9, pages 515-532.
Crossref
Crossref
Xuhui Tong, Rong Tang, Jin Xu, Wei Wang, Yingjun Zhao, Xianjun Yu & Si Shi. (2022) Liquid–liquid phase separation in tumor biology. Signal Transduction and Targeted Therapy 7:1.
Crossref
Crossref
Ryan P. Barnes, Mariarosaria de Rosa, Sanjana A. Thosar, Ariana C. Detwiler, Vera Roginskaya, Bennett Van Houten, Marcel P. Bruchez, Jacob Stewart-Ornstein & Patricia L. Opresko. (2022) Telomeric 8-oxo-guanine drives rapid premature senescence in the absence of telomere shortening. Nature Structural & Molecular Biology 29:7, pages 639-652.
Crossref
Crossref
Ragini Bhargava, Michelle Lee Lynskey & Roderick J. O’Sullivan. (2022) New twists to the ALTernative endings at telomeres. DNA Repair 115, pages 103342.
Crossref
Crossref
Kirsten A. Brenner & Jayakrishnan Nandakumar. (2022) Consequences of telomere replication failure: the other end-replication problem. Trends in Biochemical Sciences 47:6, pages 506-517.
Crossref
Crossref
Kailong Hou, Yuyang Yu, Duda Li, Yanduo Zhang, Ke Zhang, Jinkai Tong, Kunxian Yang & Shuting Jia. (2022) Alternative Lengthening of Telomeres and Mediated Telomere Synthesis. Cancers 14:9, pages 2194.
Crossref
Crossref
Paula Aguilera, Marion Dubarry, Julien Hardy, Michael Lisby, Marie‐Noëlle Simon & Vincent Géli. (2022)
Telomeric C‐circles localize at nuclear pore complexes in
Saccharomyces cerevisiae
. The EMBO Journal 41:6.
Crossref
Crossref
Robert Lu & Hilda A. Pickett. (2022) Telomeric replication stress: the beginning and the end for alternative lengthening of telomeres cancers. Open Biology 12:3.
Crossref
Crossref
Jiameng Dan, Zhongcheng Zhou, Fang Wang, Hua Wang, Renpeng Guo, David L. Keefe & Lin Liu. (2022) Zscan4 Contributes to Telomere Maintenance in Telomerase-Deficient Late Generation Mouse ESCs and Human ALT Cancer Cells. Cells 11:3, pages 456.
Crossref
Crossref
Isaac Armendáriz-Castillo, Katherine Hidalgo-Fernández, Andy Pérez-Villa, Jennyfer M. García-Cárdenas, Andrés López-Cortés & Santiago Guerrero. (2022) Identification of Key Proteins from the Alternative Lengthening of Telomeres-Associated Promyelocytic Leukemia Nuclear Bodies Pathway. Biology 11:2, pages 185.
Crossref
Crossref
Duda Li, Kailong Hou, Ke Zhang & Shuting Jia. (2022) Regulation of Replication Stress in Alternative Lengthening of Telomeres by Fanconi Anaemia Protein. Genes 13:2, pages 180.
Crossref
Crossref
Soffía R. Gunnarsdottir, Hördur Bjarnason, Birna Thorvaldsdottir, Felice Paland, Margrét Steinarsdottir, Jórunn E. Eyfjörd & Sigrídur K. Bödvarsdottir. (2021) BRCA2 Haploinsufficiency in Telomere Maintenance. Genes 13:1, pages 83.
Crossref
Crossref
Chuanle Wang, Zhou Songyang & Yan Huang. (2021) TRIM28 inhibits alternative lengthening of telomere phenotypes by protecting SETDB1 from degradation. Cell & Bioscience 11:1.
Crossref
Crossref
Xiaohua Wu & Anna Malkova. (2021) Break-induced replication mechanisms in yeast and mammals. Current Opinion in Genetics & Development 71, pages 163-170.
Crossref
Crossref
Jonathan Barroso-González, Laura García-Expósito, Pablo Galaviz, Michelle Lee Lynskey, Joshua A.M. Allen, SongMy Hoang, Simon C. Watkins, Hilda A. Pickett & Roderick J. O’Sullivan. (2021) Anti-recombination function of MutSα restricts telomere extension by ALT-associated homology-directed repair. Cell Reports 37:10, pages 110088.
Crossref
Crossref
Lia Pinto, Hanane Baidarjad, Natacha Entz-Werlé & Eric Van Dyck. (2021) Impact of Chromatin Dynamics and DNA Repair on Genomic Stability and Treatment Resistance in Pediatric High-Grade Gliomas. Cancers 13:22, pages 5678.
Crossref
Crossref
Thomas Kent & David Clynes. (2021) Alternative Lengthening of Telomeres: Lessons to Be Learned from Telomeric DNA Double-Strand Break Repair. Genes 12:11, pages 1734.
Crossref
Crossref
Yuan-Yin Chen, Rebecca Dagg, Yuchen Zhang, Joyce H. Y. Lee, Robert Lu, Nancy Martin La Rotta, Sandra Sampl, Medina Korkut-Demirbaş, Klaus Holzmann, Loretta M. S. Lau, Roger R. Reddel & Jeremy D. Henson. (2021) The C-Circle Biomarker Is Secreted by Alternative-Lengthening-of-Telomeres Positive Cancer Cells inside Exosomes and Provides a Blood-Based Diagnostic for ALT Activity. Cancers 13:21, pages 5369.
Crossref
Crossref
Noa Lamm, Samuel Rogers & Anthony J. Cesare. (2021) Chromatin mobility and relocation in DNA repair. Trends in Cell Biology 31:10, pages 843-855.
Crossref
Crossref
Lu Xu, Kexiong Zhang & Yu-Sheng Cong. (2021) The role of telomere dysfunction in genomic instability and age-related diseases. Genome Instability & Disease 2:5, pages 292-301.
Crossref
Crossref
Galina Glousker & Joachim Lingner. (2021) Challenging endings: How telomeres prevent fragility. BioEssays 43:10, pages 2100157.
Crossref
Crossref
Isabel E. Wassing, Emily Graham, Xanita Saayman, Lucia Rampazzo, Christine Ralf, Andrew Bassett & Fumiko Esashi. (2021) The RAD51 recombinase protects mitotic chromatin in human cells. Nature Communications 12:1.
Crossref
Crossref
Balakrishna Koneru, Ahsan Farooqi, Thinh H. Nguyen, Wan Hsi Chen, Ashly HindleCody Eslinger, Monish Ram Makena, Trevor A. BurrowJoanne Wilson, Aaron Smith, Venkatesh Pilla Reddy, Elaine Cadogan, Stephen T. Durant & C. Patrick Reynolds. (2021) ALT neuroblastoma chemoresistance due to telomere dysfunction–induced ATM activation is reversible with ATM inhibitor AZD0156. Science Translational Medicine 13:607.
Crossref
Crossref
Jesmin Akter & Takehiko Kamijo. (2021) How Do Telomere Abnormalities Regulate the Biology of Neuroblastoma?. Biomolecules 11:8, pages 1112.
Crossref
Crossref
Xiao Wu & Bin Wang. (2021) Abraxas suppresses DNA end resection and limits break-induced replication by controlling SLX4/MUS81 chromatin loading in response to TOP1 inhibitor-induced DNA damage. Nature Communications 12:1.
Crossref
Crossref
Bibo Li. (2021) Keeping Balance Between Genetic Stability and Plasticity at the Telomere and Subtelomere of Trypanosoma brucei. Frontiers in Cell and Developmental Biology 9.
Crossref
Crossref
Sunny Y Yang, Emily Y C Chang, Joanne Lim, Harwood H Kwan, David Monchaud, Stephen Yip, Peter C Stirling & Judy M Y Wong. (2021) G-quadruplexes mark alternative lengthening of telomeres. NAR Cancer 3:3.
Crossref
Crossref
Lorenza Garribba, Ivan Vogel, Mads Lerdrup, Marisa M. Gonçalves Dinis, Liqun Ren & Ying Liu. (2021) Folate Deficiency Triggers the Abnormal Segregation of a Region With Large Cluster of CG-Rich Trinucleotide Repeats on Human Chromosome 2. Frontiers in Genetics 12.
Crossref
Crossref
Aleksandra Lezaja, Andreas Panagopoulos, Yanlin Wen, Edison Carvalho, Ralph Imhof & Matthias Altmeyer. (2021) RPA shields inherited DNA lesions for post-mitotic DNA synthesis. Nature Communications 12:1.
Crossref
Crossref
Z.W. KocklerB. OsiaR. LeeK. MusmakerA. Malkova. (2021) Repair of DNA Breaks by Break-Induced Replication. Annual Review of Biochemistry 90:1, pages 165-191.
Crossref
Crossref
Bruno Silva, Rajika Arora, Silvia Bione & Claus M. Azzalin. (2021) TERRA transcription destabilizes telomere integrity to initiate break-induced replication in human ALT cells. Nature Communications 12:1.
Crossref
Crossref
Aleksandra Lezaja & Matthias Altmeyer. (2021) Dealing with DNA lesions: When one cell cycle is not enough. Current Opinion in Cell Biology 70, pages 27-36.
Crossref
Crossref
Martina Valenzuela, Roberta Amato, Antonella Sgura, Antonio Antoccia & Francesco Berardinelli. (2021) The Multiple Facets of ATRX Protein. Cancers 13:9, pages 2211.
Crossref
Crossref
Jennifer J. Lee, Junyeop Lee & Hyunsook Lee. (2021) Alternative paths to telomere elongation. Seminars in Cell & Developmental Biology 113, pages 88-96.
Crossref
Crossref
Isabel E. Wassing & Fumiko Esashi. (2021) RAD51: Beyond the break. Seminars in Cell & Developmental Biology 113, pages 38-46.
Crossref
Crossref
Chia-Wei Yang, Meng-Hsun Hsieh, Hao-Jhe Sun & Shu-Chun Teng. (2021) Nuclear envelope tethering inhibits the formation of ALT-associated PML bodies in ALT cells. Aging 13:7, pages 10490-10516.
Crossref
Crossref
Simon Willaume, Emilie Rass, Paula Fontanilla-Ramirez, Angela Moussa, Paul Wanschoor & Pascale Bertrand. (2021) A Link between Replicative Stress, Lamin Proteins, and Inflammation. Genes 12:4, pages 552.
Crossref
Crossref
Camille Henry & Sarah S. Henrikus. (2021) Elucidating Recombination Mediator Function Using Biophysical Tools. Biology 10:4, pages 288.
Crossref
Crossref
Erin Bonnell, Emeline Pasquier & Raymund J. Wellinger. (2021) Telomere Replication: Solving Multiple End Replication Problems. Frontiers in Cell and Developmental Biology 9.
Crossref
Crossref
Mohammad Shoeb, Helen C.S. Meier & James M. Antonini. (2021) Telomeres in toxicology: Occupational health. Pharmacology & Therapeutics 220, pages 107742.
Crossref
Crossref
Michelle Shen, Adrian Young & Chantal Autexier. (2021) PCNA, a focus on replication stress and the alternative lengthening of telomeres pathway. DNA Repair 100, pages 103055.
Crossref
Crossref
Maya Raghunandan, Dan Geelen, Eva Majerova & Anabelle Decottignies. (2021)
NHP2 downregulation counteracts h
TR
‐mediated activation of the DNA damage response at ALT telomeres
. The EMBO Journal 40:6.
Crossref
Crossref
Jia-Min Zhang, Marie-Michelle Genois, Jian Ouyang, Li Lan & Lee Zou. (2021) Alternative lengthening of telomeres is a self-perpetuating process in ALT-associated PML bodies. Molecular Cell 81:5, pages 1027-1042.e4.
Crossref
Crossref
Ilaria Rosso & Fabrizio d’Adda di Fagagna. (2020) Detection of Telomeric DNA:RNA Hybrids Using TeloDRIP-qPCR. International Journal of Molecular Sciences 21:24, pages 9774.
Crossref
Crossref
Eun Young Yu, Syed S. Zahid, Swapna Ganduri, Jeanette H. Sutherland, Min Hsu, William K. Holloman & Neal F. Lue. (2020) Structurally distinct telomere-binding proteins in Ustilago maydis execute non-overlapping functions in telomere replication, recombination, and protection. Communications Biology 3:1.
Crossref
Crossref
Galina Glousker, Anna‐Sophia Briod, Manfredo Quadroni & Joachim Lingner. (2020)
Human shelterin protein
POT
1 prevents severe telomere instability induced by homology‐directed
DNA
repair
. The EMBO Journal 39:23.
Crossref
Crossref
Hongzhen Wang, Xin Liu & Guiying Li. (2020) Explore a novel function of human condensins in cellular senescence. Cell & Bioscience 10:1.
Crossref
Crossref
Jia-Min Zhang & Lee Zou. (2020) Alternative lengthening of telomeres: from molecular mechanisms to therapeutic outlooks. Cell & Bioscience 10:1.
Crossref
Crossref
Alexandra M. Pinzaru, Mike Kareh, Noa Lamm, Eros Lazzerini-Denchi, Anthony J. Cesare & Agnel Sfeir. (2020) Replication stress conferred by POT1 dysfunction promotes telomere relocalization to the nuclear pore. Genes & Development 34:23-24, pages 1619-1636.
Crossref
Crossref
Alisa Atkins, Michelle J Xu, Maggie Li, Nathaniel P Rogers, Marina V Pryzhkova & Philip W Jordan. (2020) SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis. eLife 9.
Crossref
Crossref
Zhe Yang, Kaori K. Takai, Courtney A. Lovejoy & Titia de Lange. (2020) Break-induced replication promotes fragile telomere formation. Genes & Development 34:19-20, pages 1392-1405.
Crossref
Crossref
Agustina P. Bertolin, Jean-Sébastien Hoffmann & Vanesa Gottifredi. (2020) Under-Replicated DNA: The Byproduct of Large Genomes?. Cancers 12:10, pages 2764.
Crossref
Crossref
Tracy M. Bryan. (2020) G-Quadruplexes at Telomeres: Friend or Foe?. Molecules 25:16, pages 3686.
Crossref
Crossref
Lorenza Garribba, Victoria A. BjerregaardMarisa M. Gonçalves Dinis, Özgün Özer, Wei WuDespoina Sakellariou, Javier Pena-Diaz, Ian D. Hickson & Ying Liu. (2020) Folate stress induces SLX1- and RAD51-dependent mitotic DNA synthesis at the fragile X locus in human cells. Proceedings of the National Academy of Sciences 117:28, pages 16527-16536.
Crossref
Crossref
Therese Wilhelm, Maha Said & Valeria Naim. (2020) DNA Replication Stress and Chromosomal Instability: Dangerous Liaisons. Genes 11:6, pages 642.
Crossref
Crossref
Emily Mason‐Osann, Katherine Terranova, Nicholas Lupo, Ying Jie Lock, Lisa M Carson & Rachel Litman Flynn. (2020) RAD54 promotes alternative lengthening of telomeres by mediating branch migration. EMBO reports 21:6.
Crossref
Crossref
Wei Wu, Rahul Bhowmick, Ivan Vogel, Özgün Özer, Fiorella Ghisays, Roshan S. Thakur, Esther Sanchez de Leon, Philipp H. Richter, Liqun Ren, John H. Petrini, Ian D. Hickson & Ying Liu. (2020) RTEL1 suppresses G-quadruplex-associated R-loops at difficult-to-replicate loci in the human genome. Nature Structural & Molecular Biology 27:5, pages 424-437.
Crossref
Crossref
Meichun Xing, Fengjiao Zhang, Hongwei Liao, Sisi Chen, Luanqing Che, Xiaohui Wang, Zhengqiang Bao, Fang Ji, Gaoying Chen, Huihui Zhang, Wen Li, Zhihua Chen, Ying Liu, Ian D. Hickson, Huahao Shen & Songmin Ying. (2020) Replication Stress Induces ATR/CHK1-Dependent Nonrandom Segregation of Damaged Chromosomes. Molecular Cell 78:4, pages 714-724.e5.
Crossref
Crossref
Prem Singh Yadav & Abubakar Muhammad Wakil. 2020. Telomerase and non-Telomerase Mechanisms of Telomere Maintenance. Telomerase and non-Telomerase Mechanisms of Telomere Maintenance.
Roberta Amato, Martina Valenzuela, Francesco Berardinelli, Erica Salvati, Carmen Maresca, Stefano Leone, Antonio Antoccia & Antonella Sgura. (2020) G-quadruplex Stabilization Fuels the ALT Pathway in ALT-positive Osteosarcoma Cells. Genes 11:3, pages 304.
Crossref
Crossref
Song My Hoang & Roderick J. O’Sullivan. (2020) Alternative Lengthening of Telomeres: Building Bridges To Connect Chromosome Ends. Trends in Cancer 6:3, pages 247-260.
Crossref
Crossref
Sara Ovejero, Avelino Bueno & María P. Sacristán. (2020) Working on Genomic Stability: From the S-Phase to Mitosis. Genes 11:2, pages 225.
Crossref
Crossref
Jun Tan, Meihan Duan, Tribhuwan Yadav, Laiyee Phoon, Xiangyu Wang, Jia-Min Zhang, Lee Zou & Li Lan. (2020) An R-loop-initiated CSB–RAD52–POLD3 pathway suppresses ROS-induced telomeric DNA breaks. Nucleic Acids Research 48:3, pages 1285-1300.
Crossref
Crossref
Veronica Cherdyntseva & Sarantis Gagos. (2020) Chromosome extremities under the microscopy lens: molecular cytogenetics in telomere research. Current Opinion in Genetics & Development 60, pages 69-76.
Crossref
Crossref
Alexander P Sobinoff & Hilda A Pickett. (2020) Mechanisms that drive telomere maintenance and recombination in human cancers. Current Opinion in Genetics & Development 60, pages 25-30.
Crossref
Crossref
Aurore Sommer & Nicola J. Royle. (2020) ALT: A Multi-Faceted Phenomenon. Genes 11:2, pages 133.
Crossref
Crossref
Thomas Kent, Deanne Gracias, Samuel Shepherd & David Clynes. (2020) Alternative Lengthening of Telomeres in Pediatric Cancer: Mechanisms to Therapies. Frontiers in Oncology 9.
Crossref
Crossref
Rosa Maria Porreca, Emilia Herrera-Moyano, Eleni Skourti, Pui Pik Law, Roser Gonzalez Franco, Alex Montoya, Peter Faull, Holger Kramer & Jean-Baptiste Vannier. (2020) TRF1 averts chromatin remodelling, recombination and replication dependent-break induced replication at mouse telomeres. eLife 9.
Crossref
Crossref
Xiaolei Pan, Yun Chen, Beena Biju, Naveed Ahmed, Joyce Kong, Marti Goldenberg, Judy Huang, Nandakumar Mohan, Stephanie Klosek, Kian Parsa, Chia-Yu Guh, Robert Lu, Hilda A. Pickett, Hsueh-Ping Chu & Dong Zhang. (2019) FANCM suppresses DNA replication stress at ALT telomeres by disrupting TERRA R-loops. Scientific Reports 9:1.
Crossref
Crossref
Mindy K. Graham, Jiyoung Kim, Joseph Da, Jacqueline A. Brosnan-Cashman, Anthony Rizzo, Javier A. Baena Del Valle, Lionel Chia, Michael Rubenstein, Christine Davis, Qizhi Zheng, Leslie Cope, Michael Considine, Michael C. Haffner, Angelo M. De Marzo, Alan K. Meeker & Christopher M. Heaphy. (2019)
Functional Loss of
ATRX
and
TERC
Activates Alternative Lengthening of Telomeres (ALT) in LAPC4 Prostate Cancer Cells
. Molecular Cancer Research 17:12, pages 2480-2491.
Crossref
Crossref
Ackermann & Fischer. (2019) Telomere Maintenance in Pediatric Cancer. International Journal of Molecular Sciences 20:23, pages 5836.
Crossref
Crossref
Rachel L. Flynn & Christopher M. Heaphy. (2019) Surviving Telomere Attrition with the MiDAS Touch. Trends in Genetics 35:11, pages 783-785.
Crossref
Crossref
Jaewon Min & Jerry W. Shay. (2019) Telomere clustering drives ALT. Aging 11:19, pages 8046-8047.
Crossref
Crossref
Jonathan Barroso-González, Laura García-Expósito, Song My Hoang, Michelle L. Lynskey, Justin L. Roncaioli, Arundhati Ghosh, Callen T. Wallace, Marco de Vitis, Mauro Modesti, Kara A. Bernstein, Saumendra N. Sarkar, Simon C. Watkins & Roderick J. O’Sullivan. (2019) RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres. Molecular Cell 76:1, pages 11-26.e7.
Crossref
Crossref
Maxime Louzon, Michael Coeurdassier, Frédéric Gimbert, Benjamin Pauget & Annette de Vaufleury. (2019) Telomere dynamic in humans and animals: Review and perspectives in environmental toxicology. Environment International 131, pages 105025.
Crossref
Crossref
Eric T. Sugarman, Gao Zhang & Jerry W. Shay. (2019) In perspective: An update on telomere targeting in cancer. Molecular Carcinogenesis 58:9, pages 1581-1588.
Crossref
Crossref
Cari L. Graber-Feesl, Kayla D. Pederson, Katherine J. Aney & Naoko Shima. (2019) Mitotic DNA Synthesis Is Differentially Regulated between Cancer and Noncancerous Cells. Molecular Cancer Research 17:8, pages 1687-1698.
Crossref
Crossref
Manisha Jalan, Kyrie S. Olsen & Simon N. Powell. (2019) Emerging Roles of RAD52 in Genome Maintenance. Cancers 11:7, pages 1038.
Crossref
Crossref
Jayaram Bhandari, Travis Karg & Kent G Golic. (2019)
Homolog-Dependent Repair Following Dicentric Chromosome Breakage in
Drosophila melanogaster
. Genetics 212:3, pages 615-630.
Crossref
Crossref
Jaewon Min, Woodring E. Wright & Jerry W. Shay. (2019) Clustered telomeres in phase-separated nuclear condensates engage mitotic DNA synthesis through BLM and RAD52. Genes & Development 33:13-14, pages 814-827.
Crossref
Crossref
Elise Fouquerel, Ryan P. Barnes, Shikhar Uttam, Simon C. Watkins, Marcel P. Bruchez & Patricia L. Opresko. (2019) Targeted and Persistent 8-Oxoguanine Base Damage at Telomeres Promotes Telomere Loss and Crisis. Molecular Cell 75:1, pages 117-130.e6.
Crossref
Crossref
Bruno Silva, Richard Pentz, Ana Margarida Figueira, Rajika Arora, Yong Woo Lee, Charlotte Hodson, Harry Wischnewski, Andrew J. Deans & Claus M. Azzalin. (2019) FANCM limits ALT activity by restricting telomeric replication stress induced by deregulated BLM and R-loops. Nature Communications 10:1.
Crossref
Crossref
Mi‐Sun Kwon, Jennifer J. Lee, Jaewon Min, Kwangwoo Hwang, Seung Gu Park, Eun‐Hye Kim, Byung Chul Kim, Jong Bhak & Hyunsook Lee. (2019) Brca2 abrogation engages with the alternative lengthening of telomeres via break‐induced replication. The FEBS Journal 286:10, pages 1841-1858.
Crossref
Crossref
Elisa Palumbo & Antonella Russo. (2019) Common fragile site instability in normal cells: Lessons and perspectives. Genes, Chromosomes and Cancer 58:5, pages 260-269.
Crossref
Crossref
Doksani. (2019) The Response to DNA Damage at Telomeric Repeats and Its Consequences for Telomere Function. Genes 10:4, pages 318.
Crossref
Crossref
Bi Ning Zhang, Andrés Bueno Venegas, Ian D. Hickson & Wai Kit Chu. (2019) DNA replication stress and its impact on chromosome segregation and tumorigenesis. Seminars in Cancer Biology 55, pages 61-69.
Crossref
Crossref
Eleonora Petti, Valentina Buemi, Antonina Zappone, Odessa Schillaci, Pamela Veneziano Broccia, Roberto Dinami, Silvia Matteoni, Roberta Benetti & Stefan Schoeftner. (2019) SFPQ and NONO suppress RNA:DNA-hybrid-related telomere instability. Nature Communications 10:1.
Crossref
Crossref
Anna Y. Aksenova & Sergei M. Mirkin. (2019) At the Beginning of the End and in the Middle of the Beginning: Structure and Maintenance of Telomeric DNA Repeats and Interstitial Telomeric Sequences. Genes 10:2, pages 118.
Crossref
Crossref
Jia-Min Zhang, Tribhuwan Yadav, Jian Ouyang, Li Lan & Lee Zou. (2019) Alternative Lengthening of Telomeres through Two Distinct Break-Induced Replication Pathways. Cell Reports 26:4, pages 955-968.e3.
Crossref
Crossref
Caroline T.Y. Cheung, Rajkumar S. Kalra, Sunil C. Kaul & Renu Wadhwa. 2019. Reference Module in Biomedical Sciences. Reference Module in Biomedical Sciences.
Emily Mason-Osann, Himabindu Gali & Rachel Litman Flynn. 2019. DNA Repair. DNA Repair
31
57
.
Anissia Ait Saada, Sarah A.E. Lambert & Antony M. Carr. (2018) Preserving replication fork integrity and competence via the homologous recombination pathway. DNA Repair 71, pages 135-147.
Crossref
Crossref
Shir Toubiana & Sara Selig. (2018) DNA:RNA hybrids at telomeres – when it is better to be out of the (R) loop. The FEBS Journal 285:14, pages 2552-2566.
Crossref
Crossref
J. Kramara, B. Osia & A. Malkova. (2018) Break-Induced Replication: The Where, The Why, and The How. Trends in Genetics 34:7, pages 518-531.
Crossref
Crossref
Michael Lee, Erdahl T Teber, Oliver Holmes, Katia Nones, Ann-Marie Patch, Rebecca A Dagg, Loretta M S Lau, Joyce H Lee, Christine E Napier, Jonathan W Arthur, Sean M Grimmond, Nicholas K Hayward, Peter A Johansson, Graham J Mann, Richard A Scolyer, James S Wilmott, Roger R Reddel, John V Pearson, Nicola Waddell & Hilda A Pickett. (2018) Telomere sequence content can be used to determine ALT activity in tumours. Nucleic Acids Research 46:10, pages 4903-4918.
Crossref
Crossref
Anna H Bizard & Ian D Hickson. (2018) Anaphase: a fortune-teller of genomic instability. Current Opinion in Cell Biology 52, pages 112-119.
Crossref
Crossref
Özgün Özer & Ian D. Hickson. (2018) Pathways for maintenance of telomeres and common fragile sites during DNA replication stress. Open Biology 8:4, pages 180018.
Crossref
Crossref
Özgün Özer, Rahul Bhowmick, Ying Liu & Ian D. Hickson. (2018) Human cancer cells utilize mitotic DNA synthesis to resist replication stress at telomeres regardless of their telomere maintenance mechanism. Oncotarget 9:22, pages 15836-15846.
Crossref
Crossref
Margaux Olivier, Cyril Charbonnel, Simon Amiard, Charles I White & Maria E Gallego. (2018) RAD51 and RTEL1 compensate telomere loss in the absence of telomerase. Nucleic Acids Research 46:5, pages 2432-2445.
Crossref
Crossref
Priyanka Verma, Robert L. Dilley, Melina T. Gyparaki & Roger A. Greenberg. 2018. Mechanisms of DNA Recombination and Genome Rearrangements: Methods to Study Homologous Recombination. Mechanisms of DNA Recombination and Genome Rearrangements: Methods to Study Homologous Recombination
107
134
.
Luca Pompili, Carlo Leonetti, Annamaria Biroccio & Erica Salvati. (2017) Diagnosis and treatment of ALT tumors: is Trabectedin a new therapeutic option?. Journal of Experimental & Clinical Cancer Research 36:1.
Crossref
Crossref
Alexander P. Sobinoff & Hilda A. Pickett. (2017) Alternative Lengthening of Telomeres: DNA Repair Pathways Converge. Trends in Genetics 33:12, pages 921-932.
Crossref
Crossref
Tsung-Po Lai, Ning Zhang, Jungsik Noh, Ilgen Mender, Enzo Tedone, Ejun Huang, Woodring E. Wright, Gaudenz Danuser & Jerry W. Shay. (2017) A method for measuring the distribution of the shortest telomeres in cells and tissues. Nature Communications 8:1.
Crossref
Crossref