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Molecular and Cellular Biology Volume 26, 2006 - Issue 23
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Article

The LRS and SIN Domains: Two Structurally Equivalent but Functionally Distinct Nucleosomal Surfaces Required for Transcriptional Silencing

Christopher J. Fry1 Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts01605
,
Anne Norris2 Department of Molecular Biology and Genetics and High Throughput Biology Center, The Johns Hopkins University, Baltimore, Maryland21205
,
Michael Cosgrove3 Department of Biology, Syracuse University, 406D Lyman Hall, 108 College Place, Syracuse, New York13244
,
Jef D. Boeke2 Department of Molecular Biology and Genetics and High Throughput Biology Center, The Johns Hopkins University, Baltimore, Maryland21205
&
Craig L. Peterson1 Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts01605Correspondence[email protected]
Pages 9045-9059 | Received 09 Feb 2006, Accepted 14 Sep 2006, Published online: 27 Mar 2023

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McKenna N. M. Kyriss, Yi Jin, Isaura J. Gallegos, James A. Sanford & John J. Wyrick. (2010) Novel Functional Residues in the Core Domain of Histone H2B Regulate Yeast Gene Expression and Silencing and Affect the Response to DNA Damage. Molecular and Cellular Biology 30:14, pages 3503-3518.
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Michael S Cosgrove. (2007) Histone proteomics and the epigenetic regulation of nucleosome mobility. Expert Review of Proteomics 4:4, pages 465-478.
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Articles from other publishers (21)

Eric M. Small & Mary Ann Osley. (2023) A screen for histone mutations that affect quiescence in S. cerevisiae . The FEBS Journal 290:14, pages 3539-3562.
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Mzwanele Ngubo, Jessica Laura Reid & Hugh–George Patterton. (2022) Distinct structural groups of histone H3 and H4 residues have divergent effects on chronological lifespan in Saccharomyces cerevisiae. PLOS ONE 17:5, pages e0268760.
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Kathiresan Selvam, Sheikh Arafatur Rahman & Shisheng Li. (2019) Histone H4 H75E mutation attenuates global genomic and Rad26-independent transcription-coupled nucleotide excision repair. Nucleic Acids Research 47:14, pages 7392-7401.
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Callum J. O’KaneEdel M. Hyland. (2019) Yeast epigenetics: the inheritance of histone modification states. Bioscience Reports 39:5.
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Pilendra K. Thakre, Athira SV, Upendarrao Golla, Sakshi Chauhan & Raghuvir S. Tomar. (2018) Previously uncharacterized amino acid residues in histone H3 and H4 mutants with roles in DNA damage repair response and cellular aging . The FEBS Journal 286:6, pages 1154-1173.
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Payel Sen, Weiwei Dang, Greg Donahue, Junbiao Dai, Jean Dorsey, Xiaohua Cao, Wei Liu, Kajia Cao, Rocco Perry, Jun Yeop Lee, Brian M. Wasko, Daniel T. Carr, Chong He, Brett Robison, John Wagner, Brian D. Gregory, Matt Kaeberlein, Brian K. Kennedy, Jef D. Boeke & Shelley L. Berger. (2015) H3K36 methylation promotes longevity by enhancing transcriptional fidelity. Genes & Development 29:13, pages 1362-1376.
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Gregory D. Bowman & Michael G. Poirier. (2014) Post-Translational Modifications of Histones That Influence Nucleosome Dynamics. Chemical Reviews 115:6, pages 2274-2295.
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Cecil J. Howard, Ruixuan R. Yu, Miranda L. Gardner, John C. Shimko & Jennifer J. Ottesen. 2015. Protein Ligation and Total Synthesis II. Protein Ligation and Total Synthesis II 193 226 .
Karim-Jean ArmacheJoseph D. GarlickDaniele CanzioGeeta J. NarlikarRobert E. Kingston. (2011) Structural Basis of Silencing: Sir3 BAH Domain in Complex with a Nucleosome at 3.0 Å Resolution. Science 334:6058, pages 977-982.
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Michel Fink, Jeffrey S. Thompson & Fritz Thoma. (2011) Contributions of Histone H3 Nucleosome Core Surface Mutations to Chromatin Structures, Silencing and DNA Repair. PLoS ONE 6:10, pages e26210.
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Marek SimonJustin A. NorthJohn C. Shimko, Robert A. FortiesMichelle B. FerdinandMridula ManoharMeng Zhang, Richard Fishel, Jennifer J. Ottesen & Michael G. Poirier. (2011) Histone fold modifications control nucleosome unwrapping and disassembly. Proceedings of the National Academy of Sciences 108:31, pages 12711-12716.
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Eugenia T Prescott, Alexias Safi & Laura N Rusche. (2011) A Region of the Nucleosome Required for Multiple Types of Transcriptional Silencing in Saccharomyces cerevisiae . Genetics 188:3, pages 535-548.
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Ronita Nag & Michael J. Smerdon. (2009) Altering the chromatin landscape for nucleotide excision repair. Mutation Research/Reviews in Mutation Research 682:1, pages 13-20.
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Hailiang Huang, Alexandra M. Maertens, Edel M. Hyland, Junbiao Dai, Anne Norris, Jef D. Boeke & Joel S. Bader. (2009) HistoneHits: A database for histone mutations and their phenotypes. Genome Research 19:4, pages 674-681.
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Shubho Chaudhuri, John J. Wyrick & Michael J. Smerdon. (2009) Histone H3 Lys79 methylation is required for efficient nucleotide excision repair in a silenced locus of Saccharomyces cerevisiae. Nucleic Acids Research 37:5, pages 1690-1700.
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Anne Norris, Mario A. Bianchet & Jef D. Boeke. (2008) Compensatory Interactions between Sir3p and the Nucleosomal LRS Surface Imply Their Direct Interaction. PLoS Genetics 4:12, pages e1000301.
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Hai-Ning Du, Ian M. Fingerman & Scott D. Briggs. (2008) Histone H3 K36 methylation is mediated by a trans -histone methylation pathway involving an interaction between Set2 and histone H4 . Genes & Development 22:20, pages 2786-2798.
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Bo Yang, Jeanette Britton & Ann L. Kirchmaier. (2008) Insights into the Impact of Histone Acetylation and Methylation on Sir Protein Recruitment, Spreading, and Silencing in Saccharomyces cerevisiae. Journal of Molecular Biology 381:4, pages 826-844.
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R. Nag, F. Gong, D. Fahy & M. J. Smerdon. (2008) A single amino acid change in histone H4 enhances UV survival and DNA repair in yeast. Nucleic Acids Research 36:11, pages 3857-3866.
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Mohammed Altaf, Rhea T. Utley, Nicolas Lacoste, Song Tan, Scott D. Briggs & Jacques Côté. (2007) Interplay of Chromatin Modifiers on a Short Basic Patch of Histone H4 Tail Defines the Boundary of Telomeric Heterochromatin. Molecular Cell 28:6, pages 1002-1014.
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Feng Xu, Qiongyi Zhang, Kangling Zhang, Wei Xie & Michael Grunstein. (2007) Sir2 Deacetylates Histone H3 Lysine 56 to Regulate Telomeric Heterochromatin Structure in Yeast. Molecular Cell 27:6, pages 890-900.
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