Citations (63)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (6)
So-Hyeon Kim, Sun-Ju Yi, Hyerim Lee, Ji-Hyun Kim, Myung-ju Oh, Eun-Ju Song, Kyunghwan Kim & Byung H. Jhun. (2019) β2-Adrenergic receptor (β2-AR) agonist formoterol suppresses differentiation of L6 myogenic cells by blocking PI3K–AKT pathway. Animal Cells and Systems 23:1, pages 18-25.
Read now
Read now
Saviz Ehyai, Mathew G. Dionyssiou, Joseph W. Gordon, Declan Williams, K. W. Michael Siu & John C. McDermott. (2016) A p38 Mitogen-Activated Protein Kinase-Regulated Myocyte Enhancer Factor 2–β-Catenin Interaction Enhances Canonical Wnt Signaling. Molecular and Cellular Biology 36:2, pages 330-346.
Read now
Read now
Bryan D. Spiegelberg. (2013) G protein coupled-receptor signaling and reversible lysine acetylation. Journal of Receptors and Signal Transduction 33:5, pages 261-266.
Read now
Read now
Wei Ye, Kang Xu, Dongsheng Huang, Anjing Liang, Yan Peng, Weirong Zhu & Chunhai Li. (2011) Age-Related Increases of Macroautophagy and Chaperone-Mediated Autophagy in Rat Nucleus Pulposus. Connective Tissue Research 52:6, pages 472-478.
Read now
Read now
Tetsuaki Miyake, Nezeka S. Alli & John C. McDermott. (2010) Nuclear Function of Smad7 Promotes Myogenesis. Molecular and Cellular Biology 30:3, pages 722-735.
Read now
Read now
Elena Kozhemyakina, Todd Cohen, Tso-Pang Yao & Andrew B. Lassar. (2009) Parathyroid Hormone-Related Peptide Represses Chondrocyte Hypertrophy through a Protein Phosphatase 2A/Histone Deacetylase 4/MEF2 Pathway. Molecular and Cellular Biology 29:21, pages 5751-5762.
Read now
Read now
Articles from other publishers (57)
Kiros Haddish & Jong Won Yun. (2023) Dopamine receptor D4 (DRD4) negatively regulates UCP1- and ATP-dependent thermogenesis in 3T3-L1 adipocytes and C2C12 muscle cells. Pflügers Archiv - European Journal of Physiology 475:6, pages 757-773.
Crossref
Crossref
James D. Cornwell & John C. McDermott. (2023) MEF2 in cardiac hypertrophy in response to hypertension. Trends in Cardiovascular Medicine 33:4, pages 204-212.
Crossref
Crossref
Amira Moustafa, Sara Hashemi, Gurnoor Brar, Jörg Grigull, Siemon H. S. Ng, Declan Williams, Gerold Schmitt-Ulms & John C. McDermott. (2023) The MEF2A transcription factor interactome in cardiomyocytes. Cell Death & Disease 14:4.
Crossref
Crossref
Malwina Lisek, Oskar Przybyszewski, Ludmila Zylinska, Feng Guo & Tomasz Boczek. (2023) The Role of MEF2 Transcription Factor Family in Neuronal Survival and Degeneration. International Journal of Molecular Sciences 24:4, pages 3120.
Crossref
Crossref
Kenley Joule Pierre & Jacques J. Tremblay. (2022) Differential Response of Transcription Factors to Activated Kinases in Steroidogenic and Non-Steroidogenic Cells. International Journal of Molecular Sciences 23:21, pages 13153.
Crossref
Crossref
Yura Son & Chad M. Paton. (2022) A Review of free fatty acid-induced cell signaling, angiopoietin-like protein 4, and skeletal muscle differentiation. Frontiers in Physiology 13.
Crossref
Crossref
Mai Yoshida, Norihide Yokoi, Harumi Takahashi, Naoya Hatano, Tomohide Hayami, Wataru Ogawa & Susumu Seino. (2022) O-GlcNAcylation of myocyte-specific enhancer factor 2D negatively regulates insulin secretion from pancreatic β-cells. Biochemical and Biophysical Research Communications 605, pages 90-96.
Crossref
Crossref
Luke Erber, Shirelle Liu, Yao Gong, Phu Tran & Yue Chen. (2022) Quantitative Proteome and Transcriptome Dynamics Analysis Reveals Iron Deficiency Response Networks and Signature in Neuronal Cells. Molecules 27:2, pages 484.
Crossref
Crossref
Pin Wang, Juan Zhao & Xiulian Sun. (2021) DYRK1A phosphorylates MEF2D and decreases its transcriptional activity. Journal of Cellular and Molecular Medicine 25:13, pages 6082-6093.
Crossref
Crossref
Stefanie Maria Werhahn, Julia S. Kreusser, Marco Hagenmüller, Jan Beckendorf, Nathalie Diemert, Sophia Hoffmann, Jobst-Hendrik Schultz, Johannes Backs & Matthias Dewenter. (2021) Adaptive versus maladaptive cardiac remodelling in response to sustained β-adrenergic stimulation in a new ‘ISO on/off model’. PLOS ONE 16:6, pages e0248933.
Crossref
Crossref
Sunghyun Cho, Prabuddha Manjula, Minjun Kim, Eunjin Cho, Dooho Lee, Seung Hwan Lee, Jun Heon Lee & Dongwon Seo. (2021) Comparison of Selection Signatures between Korean Native and Commercial Chickens Using 600K SNP Array Data. Genes 12:6, pages 824.
Crossref
Crossref
Javier Durán & Johannes Backs. 2021. Epigenetics in Cardiovascular Disease. Epigenetics in Cardiovascular Disease
41
52
.
Tao He, Jiale Huang, Lan Chen, Gang Han, David Stanmore, Jutta Krebs-Haupenthal, Metin Avkiran, Marco Hagenmüller & Johannes Backs. (2020) Cyclic AMP represses pathological MEF2 activation by myocyte-specific hypo-phosphorylation of HDAC5. Journal of Molecular and Cellular Cardiology 145, pages 88-98.
Crossref
Crossref
Hongjia Ouyang, Jiao Yu, Xiaolan Chen, Zhijun Wang & Qinghua Nie. (2020) A novel transcript of MEF2D promotes myoblast differentiation and its variations associated with growth traits in chicken. PeerJ 8, pages e8351.
Crossref
Crossref
Perrine Castets, Nathalie Rion, Marine Théodore, Denis Falcetta, Shuo Lin, Markus Reischl, Franziska Wild, Laurent Guérard, Christopher Eickhorst, Marielle Brockhoff, Maitea Guridi, Chikwendu Ibebunjo, Joseph Cruz, Michael Sinnreich, Rüdiger Rudolf, David J. Glass & Markus A. Rüegg. (2019) mTORC1 and PKB/Akt control the muscle response to denervation by regulating autophagy and HDAC4. Nature Communications 10:1.
Crossref
Crossref
Kiran Madugula, Ria Mulherkar, Zafar K. Khan, DeGaulle I. Chigbu, Dip Patel, Edward W. Harhaj & Pooja Jain. (2019) MEF-2 isoforms' (A-D) roles in development and tumorigenesis. Oncotarget 10:28, pages 2755-2787.
Crossref
Crossref
Kiran Nakka, Claudia Ghigna, Davide Gabellini & F. Jeffrey Dilworth. (2018) Diversification of the muscle proteome through alternative splicing. Skeletal Muscle 8:1.
Crossref
Crossref
Jared T. Field, Matthew D. Martens, Wajihah Mughal, Yan Hai, Donald Chapman, Grant M. Hatch, Tammy L. Ivanco, William Diehl-Jones & Joseph W. Gordon. (2018) Misoprostol regulates Bnip3 repression and alternative splicing to control cellular calcium homeostasis during hypoxic stress. Cell Death Discovery 4:1.
Crossref
Crossref
Rachel D. Penrod, Maria B. Carreira, Makoto Taniguchi, Jaswinder Kumar, Stephanie A. Maddox & Christopher W. Cowan. (2018) Novel role and regulation of HDAC4 in cocaine-related behaviors. Addiction Biology 23:2, pages 653-664.
Crossref
Crossref
Xiao Chen, Bing Gao, Murugavel Ponnusamy, Zhijuan Lin & Jia Liu. (2017) MEF2 signaling and human diseases. Oncotarget 8:67, pages 112152-112165.
Crossref
Crossref
Michael V. Taylor & Simon M. Hughes. (2017) Mef2 and the skeletal muscle differentiation program. Seminars in Cell & Developmental Biology 72, pages 33-44.
Crossref
Crossref
Okechukwu Clinton Ifegwu, Guleid Awale, Komal Rajpura, Kevin W-H. Lo & Cato T. Laurencin. (2017) Harnessing cAMP signaling in musculoskeletal regenerative engineering. Drug Discovery Today 22:7, pages 1027-1044.
Crossref
Crossref
S. W. Tobin, S. Hashemi, K. Dadson, S. Turdi, K. Ebrahimian, J. Zhao, G. Sweeney, J. Grigull & J. C. McDermott. (2017) Heart Failure and MEF2 Transcriptome Dynamics in Response to β-Blockers. Scientific Reports 7:1.
Crossref
Crossref
Cody Desjardins & Francisco Naya. (2016) The Function of the MEF2 Family of Transcription Factors in Cardiac Development, Cardiogenomics, and Direct Reprogramming. Journal of Cardiovascular Development and Disease 3:3, pages 26.
Crossref
Crossref
Eros Di Giorgio & Claudio Brancolini. (2016) Regulation of class IIa HDAC activities: it is not only matter of subcellular localization. Epigenomics 8:2, pages 251-269.
Crossref
Crossref
Julia R. Pon & Marco A. Marra. (2015) MEF2 transcription factors: developmental regulators and emerging cancer genes. Oncotarget 7:3, pages 2297-2312.
Crossref
Crossref
W Mughal, L Nguyen, S Pustylnik, S C da Silva Rosa, S Piotrowski, D Chapman, M Du, N S Alli, J Grigull, A J Halayko, M Aliani, M K Topham, R M Epand, G M Hatch, T J Pereira, S Kereliuk, J C McDermott, C Rampitsch, V W Dolinsky & J W Gordon. (2015) A conserved MADS-box phosphorylation motif regulates differentiation and mitochondrial function in skeletal, cardiac, and smooth muscle cells. Cell Death & Disease 6:10, pages e1944-e1944.
Crossref
Crossref
S Hashemi, S Wales, T Miyake & J C McDermott. (2015) Heart disease: recruitment of MEF2 activity by β−blockers wards off cardiomyocyte death. Cell Death & Disease 6:10, pages e1916-e1916.
Crossref
Crossref
S Hashemi, J Salma, S Wales & JC McDermott. (2015) Pro-survival function of MEF2 in cardiomyocytes is enhanced by β-blockers. Cell Death Discovery 1:1.
Crossref
Crossref
Keith Dadson, Subat Turdi, Sarah Hashemi, Jianzhong Zhao, Nazar Polidovitch, Sanja Beca, Peter H. Backx, John C. McDermott & Gary Sweeney. (2015) Adiponectin is required for cardiac MEF2 activation during pressure overload induced hypertrophy. Journal of Molecular and Cellular Cardiology 86, pages 102-109.
Crossref
Crossref
Hae-Ahm Lee, Min-Ji Song, Young-Mi Seok, Seol-Hee Kang, Sang-Yeob Kim & Inkyeom Kim. (2015) Histone Deacetylase 3 and 4 Complex Stimulates the Transcriptional Activity of the Mineralocorticoid Receptor. PLOS ONE 10:8, pages e0136801.
Crossref
Crossref
Sebastian Frese, Matthias Ruebner, Frank Suhr, Thierry M. Konou, Kim A. Tappe, Marco Toigo, Hans H. Jung, Christine Henke, Ruth Steigleder, Pamela L. Strissel, Hanna Huebner, Matthias W. Beckmann, Piet van der Keylen, Benedikt Schoser, Thorsten Schiffer, Laura Frese, Wilhelm Bloch & Reiner Strick. (2015) Long-Term Endurance Exercise in Humans Stimulates Cell Fusion of Myoblasts along with Fusogenic Endogenous Retroviral Genes In Vivo. PLOS ONE 10:7, pages e0132099.
Crossref
Crossref
Meiling Zhang, Bo Zhu & Judith Davie. (2015) Alternative Splicing of MEF2C pre-mRNA Controls Its Activity in Normal Myogenesis and Promotes Tumorigenicity in Rhabdomyosarcoma Cells. Journal of Biological Chemistry 290:1, pages 310-324.
Crossref
Crossref
Stephanie Wales, Sara Hashemi, Alexandre Blais & John C. McDermott. (2014) Global MEF2 target gene analysis in cardiac and skeletal muscle reveals novel regulation of DUSP6 by p38MAPK-MEF2 signaling. Nucleic Acids Research 42:18, pages 11349-11362.
Crossref
Crossref
J. Shilpa & C. S. Paulose. (2014) GABA and 5-HT chitosan nanoparticles decrease striatal neuronal degeneration and motor deficits during liver injury. Journal of Materials Science: Materials in Medicine 25:7, pages 1721-1735.
Crossref
Crossref
Lorenz H. Lehmann, Barbara C. Worst, David A. Stanmore & Johannes Backs. (2013) Histone deacetylase signaling in cardioprotection. Cellular and Molecular Life Sciences 71:9, pages 1673-1690.
Crossref
Crossref
M G Dionyssiou, S Ehyai, E Avrutin, M K Connor & J C McDermott. (2014) Glycogen synthase kinase 3β represses MYOGENIN function in alveolar rhabdomyosarcoma. Cell Death & Disease 5:2, pages e1094-e1094.
Crossref
Crossref
A. J. Rashid, C. J. Cole & S. A. Josselyn. (2014) Emerging roles for MEF2 transcription factors in memory. Genes, Brain and Behavior 13:1, pages 118-125.
Crossref
Crossref
Mathew G Dionyssiou, Jahan Salma, Mariya Bevzyuk, Stephanie Wales, Lusine Zakharyan & John C McDermott. (2013) Krüppel-like factor 6 (KLF6) promotes cell proliferation in skeletal myoblasts in response to TGFβ/Smad3 signaling. Skeletal Muscle 3:1.
Crossref
Crossref
Carol Y Ying, David Dominguez-Sola, Melissa Fabi, Ivo C Lorenz, Shafinaz Hussein, Mukesh Bansal, Andrea Califano, Laura Pasqualucci, Katia Basso & Riccardo Dalla-Favera. (2013) MEF2B mutations lead to deregulated expression of the oncogene BCL6 in diffuse large B cell lymphoma. Nature Immunology 14:10, pages 1084-1092.
Crossref
Crossref
Yewei Liu & Martin F. Schneider. (2013) Opposing HDAC4 nuclear fluxes due to phosphorylation by β-adrenergic activated protein kinase A or by activity or Epac activated CaMKII in skeletal muscle fibres. The Journal of Physiology 591:14, pages 3605-3623.
Crossref
Crossref
Soji Sebastian, Hervé Faralli, Zizhen Yao, Patricia Rakopoulos, Carmen Palii, Yi Cao, Kulwant Singh, Qi-Cai Liu, Alphonse Chu, Arif Aziz, Marjorie Brand, Stephen J. Tapscott & F. Jeffrey Dilworth. (2013) Tissue-specific splicing of a ubiquitously expressed transcription factor is essential for muscle differentiation. Genes & Development 27:11, pages 1247-1259.
Crossref
Crossref
MARTINE MÜLLER KLOSTER, ELIN HALLAN NADERI, INGVILD HAALAND, BJØRN TORE GJERTSEN, HEIDI KIIL BLOMHOFF & SOHEIL NADERI. (2013) cAMP signalling inhibits p53 acetylation and apoptosis via HDAC and SIRT deacetylases. International Journal of Oncology 42:5, pages 1815-1821.
Crossref
Crossref
Donald R. Walkinshaw, Ryan Weist, Go-Woon Kim, Linya You, Lin Xiao, Jianyun Nie, Cathy S. Li, Songping Zhao, Minghong Xu & Xiang-Jiao Yang. (2013) The Tumor Suppressor Kinase LKB1 Activates the Downstream Kinases SIK2 and SIK3 to Stimulate Nuclear Export of Class IIa Histone Deacetylases. Journal of Biological Chemistry 288:13, pages 9345-9362.
Crossref
Crossref
Donald R. Walkinshaw, Ryan Weist, Lin Xiao, Kezhi Yan, Go-Woon Kim & Xiang-Jiao Yang. (2013) Dephosphorylation at a Conserved SP Motif Governs cAMP Sensitivity and Nuclear Localization of Class IIa Histone Deacetylases*. Journal of Biological Chemistry 288:8, pages 5591-5605.
Crossref
Crossref
M.G. Dionyssiou, N.B. Nowacki, S. Hashemi, J. Zhao, A. Kerr, R.G. Tsushima & J.C. McDermott. (2013) Cross-talk between glycogen synthase kinase 3β (GSK3β) and p38MAPK regulates myocyte enhancer factor 2 (MEF2) activity in skeletal and cardiac muscle. Journal of Molecular and Cellular Cardiology 54, pages 35-44.
Crossref
Crossref
Danielle C. Lynch, David A. Dyment, Lijia Huang, Sarah M. Nikkel, Didier Lacombe, Philippe M. Campeau, Brendan Lee, Carlos A. Bacino, Jacques L. Michaud, Francois P. Bernier, FORGE Canada Consortium, Jillian S. Parboosingh & A. Micheil Innes. (2013)
Identification of Novel Mutations Confirms
Pde4d
as a Major Gene Causing Acrodysostosis
. Human Mutation 34:1, pages 97-102.
Crossref
Crossref
Maximilian A.X. Vargas, Jennifer S. Tirnauer, Nicole Glidden, Michael S. Kapiloff & Kimberly L. Dodge-Kafka. (2012) Myocyte enhancer factor 2 (MEF2) tethering to muscle selective A-kinase anchoring protein (mAKAP) is necessary for myogenic differentiation. Cellular Signalling 24:8, pages 1496-1503.
Crossref
Crossref
Rebecca Berdeaux & Randi Stewart. (2012) cAMP signaling in skeletal muscle adaptation: hypertrophy, metabolism, and regeneration. American Journal of Physiology-Endocrinology and Metabolism 303:1, pages E1-E17.
Crossref
Crossref
Jahan Salma & John C. McDermott. (2012) Suppression of a MEF2-KLF6 Survival Pathway by PKA Signaling Promotes Apoptosis in Embryonic Hippocampal Neurons. The Journal of Neuroscience 32:8, pages 2790-2803.
Crossref
Crossref
Ashraf Said Al Madhoun, Virja Mehta, Grace Li, Daniel Figeys, Nadine Wiper-Bergeron & Ilona S Skerjanc. (2011) Skeletal myosin light chain kinase regulates skeletal myogenesis by phosphorylation of MEF2C. The EMBO Journal 30:12, pages 2477-2489.
Crossref
Crossref
James DR Knight & Rashmi Kothary. (2011) The myogenic kinome: protein kinases critical to mammalian skeletal myogenesis. Skeletal Muscle 1:1, pages 29.
Crossref
Crossref
Chang Hoon Ha, Ji Young Kim, Jinjing Zhao, Weiye Wang, Bong Sook Jhun, Chelsea Wong & Zheng Gen Jin. (2010) PKA phosphorylates histone deacetylase 5 and prevents its nuclear export, leading to the inhibition of gene transcription and cardiomyocyte hypertrophy. Proceedings of the National Academy of Sciences 107:35, pages 15467-15472.
Crossref
Crossref
James G Ryall, Jarrod E Church & Gordon S Lynch. (2010) Novel role for β-adrenergic signalling in skeletal muscle growth, development and regeneration. Clinical and Experimental Pharmacology and Physiology 37:3, pages 397-401.
Crossref
Crossref
Seán P. Barry & Paul A. Townsend. 2010.
113
179
.
Yoshio Wakamatsu. (2009) Overlapped and differential expression of cAMP-dependent kinase-inhibitor isoforms during avian organogenesis period. Development, Growth & Differentiation 51:8, pages 707-714.
Crossref
Crossref
Joseph W. Gordon, Christina Pagiatakis, Jahan Salma, Min Du, John J. Andreucci, Jianzhong Zhao, Guangpei Hou, Robert L. Perry, Qinghong Dan, David Courtman, Michelle P. Bendeck & John C. McDermott. (2009) Protein Kinase A-regulated Assembly of a MEF2·HDAC4 Repressor Complex Controls c-Jun Expression in Vascular Smooth Muscle Cells. Journal of Biological Chemistry 284:28, pages 19027-19042.
Crossref
Crossref