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Article

Selective Regulation of Bone Cell Apoptosis by Translational Isoforms of the Glucocorticoid Receptor

Nick Z. Lu1 Molecular Endocrinology Group, Laboratory of Signal Transduction
,
Jennifer B. Collins2 Microarray Center, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina27709
,
Sherry F. Grissom2 Microarray Center, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina27709
&
John A. Cidlowski1 Molecular Endocrinology Group, Laboratory of Signal TransductionCorrespondence[email protected]
Pages 7143-7160 | Received 12 Feb 2007, Accepted 25 Jul 2007, Published online: 27 Mar 2023

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Ya-Lin Liu, Soonmin Jang, Shih-Min Wang, Chiu-Hao Chen & Feng-Yin Li. (2016) Investigation on critical structural motifs of ligands for triggering glucocorticoid receptor nuclear migration through molecular docking simulations. Journal of Biomolecular Structure and Dynamics 34:6, pages 1214-1231.
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Nicolas C. Nicolaides & Evangelia Charmandari. 2019. Genetics of Endocrine Diseases and Syndromes. Genetics of Endocrine Diseases and Syndromes 85 102 .
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Ana C. Liberman, Maia L. Budziñski, Clara Sokn, Romina Paula Gobbini, Anja Steininger & Eduardo Arzt. (2018) Regulatory and Mechanistic Actions of Glucocorticoids on T and Inflammatory Cells. Frontiers in Endocrinology 9.
Crossref
Jean-Didier Breton, Déborah Heydet, Lora M. Starrs, Tim Veldre & Reena Ghildyal. (2018) Molecular changes during TGF β -mediated lung fibroblast-myofibroblast differentiation: implication for glucocorticoid resistance . Physiological Reports 6:7, pages e13669.
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Georgia Balsevich, Gavin N. Petrie & Matthew N. Hill. (2017) Endocannabinoids: Effectors of glucocorticoid signaling. Frontiers in Neuroendocrinology 47, pages 86-108.
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Crossref
Petra Birth, Stefanie Schöne, Ulrich Stelzl & Sebastiaan H. Meijsing. (2017) Identification and characterization of BATF3 as a context-specific coactivator of the glucocorticoid receptor. PLOS ONE 12:7, pages e0181219.
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N. Facchinello, T. Skobo, G. Meneghetti, E. Colletti, A. Dinarello, N. Tiso, R. Costa, G. Gioacchini, O. Carnevali, F. Argenton, L. Colombo & L. Dalla Valle. (2017) nr3c1 null mutant zebrafish are viable and reveal DNA-binding-independent activities of the glucocorticoid receptor. Scientific Reports 7:1.
Crossref
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Crossref
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Crossref
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Crossref
Sofie J. Desmet & Karolien De Bosscher. (2017) Glucocorticoid receptors: finding the middle ground. Journal of Clinical Investigation 127:4, pages 1136-1145.
Crossref
Kentaro Ueno, Yumiko Ninomiya, Daisuke Hazeki, Kiminori Masuda, Yuichi Nomura & Yoshifumi Kawano. (2017) Disruption of Endothelial Cell Homeostasis Plays a Key Role in the Early Pathogenesis of Coronary Artery Abnormalities in Kawasaki Disease. Scientific Reports 7:1.
Crossref
Svetlana Bivol, Suzzanne J. Owen & Roselyn B. Rose'Meyer. (2017) Glucocorticoid-induced changes in glucocorticoid receptor mRNA and protein expression in the human placenta as a potential factor for altering fetal growth and development. Reproduction, Fertility and Development 29:5, pages 845.
Crossref
Jonathan T. Busada & John A. Cidlowski. 2017. Nuclear Receptors in Development and Disease. Nuclear Receptors in Development and Disease 147 170 .
Jesus Banuelos & Nicholas Z. Lu. (2016) A gradient of glucocorticoid sensitivity among helper T cell cytokines. Cytokine & Growth Factor Reviews 31, pages 27-35.
Crossref
William E. AckermanIVIV, Irina A. Buhimschi, Haley R. Eidem, David C. Rinker, Antonis Rokas, Kara Rood, Guomao Zhao, Taryn L. Summerfield, Mark B. Landon & Catalin S. Buhimschi. (2016) Comprehensive RNA profiling of villous trophoblast and decidua basalis in pregnancies complicated by preterm birth following intra-amniotic infection. Placenta 44, pages 23-33.
Crossref
Sofia Soto-Rodriguez, Gabriela Lopez-Armas, Sonia Luquin, Rodrigo Ramos-Zuñiga, Fernando Jauregui-Huerta, Oscar Gonzalez-Perez & Rocio E. Gonzalez-Castañeda. (2016) Rapid Eye Movement Sleep Deprivation Produces Long-Term Detrimental Effects in Spatial Memory and Modifies the Cellular Composition of the Subgranular Zone. Frontiers in Cellular Neuroscience 10.
Crossref
Shengcheng Yao, Yingnan Zhang, Xiaoyu Wang, Fengchao Zhao, Maji Sun, Xin Zheng, Hongyan Dong & Kaijin Guo. (2016) Pigment Epithelium-Derived Factor (PEDF) Protects Osteoblastic Cell Line from Glucocorticoid-Induced Apoptosis via PEDF-R. International Journal of Molecular Sciences 17:5, pages 730.
Crossref
J. Banuelos, S. Shin, Y. Cao, B. S. Bochner, L. Morales-Nebreda, G. R. S. Budinger, L. Zhou, S. Li, J. Xin, M. W. Lingen, C. Dong, R. P. Schleimer & N. Z. Lu. (2016) BCL-2 protects human and mouse Th17 cells from glucocorticoid-induced apoptosis. Allergy 71:5, pages 640-650.
Crossref
Kerstin Hartmann, Mascha Koenen, Sebastian Schauer, Stephanie Wittig-Blaich, Mubashir Ahmad, Ulrike Baschant & Jan P. Tuckermann. (2016) Molecular Actions of Glucocorticoids in Cartilage and Bone During Health, Disease, and Steroid Therapy. Physiological Reviews 96:2, pages 409-447.
Crossref
Zarqa Saif, Rebecca M. Dyson, Hannah K. Palliser, Ian M. R. Wright, Nick Lu & Vicki L. Clifton. (2016) Identification of Eight Different Isoforms of the Glucocorticoid Receptor in Guinea Pig Placenta: Relationship to Preterm Delivery, Sex and Betamethasone Exposure. PLOS ONE 11:2, pages e0148226.
Crossref
Sivapriya Ramamoorthy & John A. Cidlowski. (2016) Corticosteroids. Rheumatic Disease Clinics of North America 42:1, pages 15-31.
Crossref
John A. Cidlowski, Carl D. Malchoff & Diana M. Malchoff. 2016. Endocrinology: Adult and Pediatric. Endocrinology: Adult and Pediatric 1717 1726.e4 .
Robert H. Oakley & John A. Cidlowski. (2015) Glucocorticoid signaling in the heart: A cardiomyocyte perspective. The Journal of Steroid Biochemistry and Molecular Biology 153, pages 27-34.
Crossref
Derek W. Cain & John A. Cidlowski. (2015) Specificity and sensitivity of glucocorticoid signaling in health and disease. Best Practice & Research Clinical Endocrinology & Metabolism 29:4, pages 545-556.
Crossref
Z. Saif, N.A. Hodyl, M.J. Stark, P.J. Fuller, T. Cole, N. Lu & V.L. Clifton. (2015) Expression of eight glucocorticoid receptor isoforms in the human preterm placenta vary with fetal sex and birthweight. Placenta 36:7, pages 723-730.
Crossref
Vesna Tesic, Milka Perovic, Divna Lazic, Snezana Kojic, Kosara Smiljanic, Sabera Ruzdijic, Ljubisav Rakic & Selma Kanazir. (2015) Long-term intermittent feeding restores impaired GR signaling in the hippocampus of aged rat. The Journal of Steroid Biochemistry and Molecular Biology 149, pages 43-52.
Crossref
Jesus Banuelos, Soon Cheon Shin & Nick Z. Lu. (2015) A hotspot in the glucocorticoid receptor DNA-binding domain susceptible to loss of function mutation. Steroids 96, pages 115-120.
Crossref
T Joshi, M Johnson, R Newton & M Giembycz. (2015) An analysis of glucocorticoid receptor-mediated gene expression in BEAS-2B human airway epithelial cells identifies distinct, ligand-directed, transcription profiles with implications for asthma therapeutics. British Journal of Pharmacology 172:5, pages 1360-1378.
Crossref
Jonathan D. Turner, Sara Vernocchi, Stephanie Schmitz & Claude P. Muller. (2014) Role of the 5′-untranslated regions in post-transcriptional regulation of the human glucocorticoid receptor. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1839:11, pages 1051-1061.
Crossref
Sofie Vandevyver, Lien Dejager & Claude Libert. (2014) Comprehensive Overview of the Structure and Regulation of the Glucocorticoid Receptor. Endocrine Reviews 35:4, pages 671-693.
Crossref
Laurent Givalois. (2014) The glucocorticoid receptors regulation in Alzheimer's disease. Neurobiology of Aging 35:7, pages e17-e18.
Crossref
James P. Bridges, Angelica Schehr, Yanhua Wang, Liya Huo, Valérie Besnard, Machiko Ikegami, Jeffrey A. Whitsett & Yan Xu. (2014) Epithelial SCAP/INSIG/SREBP Signaling Regulates Multiple Biological Processes during Perinatal Lung Maturation. PLoS ONE 9:5, pages e91376.
Crossref
Z. Saif, N.A. Hodyl, E. Hobbs, A.R. Tuck, M.S. Butler, A. Osei-Kumah & V.L. Clifton. (2014) The human placenta expresses multiple glucocorticoid receptor isoforms that are altered by fetal sex, growth restriction and maternal asthma. Placenta 35:4, pages 260-268.
Crossref
Kan Chen, Kwan Man, Herold J. Metselaar, Harry L. A. Janssen, Maikel P. Peppelenbosch & Qiuwei Pan. (2014) Rationale of personalized immunosuppressive medication for hepatocellular carcinoma patients after liver transplantation. Liver Transplantation 20:3, pages 261-269.
Crossref
Judith Toneatto, Nancy L. Charó, Agostina Naselli, Melina Muñoz-Bernart, Antonella Lombardi & Graciela Piwien-Pilipuk. (2014) Corticosteroid Receptors, Their Chaperones and Cochaperones: How Do They Modulate Adipogenesis?. Nuclear Receptor Research 1.
Crossref
Jody White. 2015. Molecular Oncology. Molecular Oncology 367 377 .
Dariusz Ratman, Wim Vanden Berghe, Lien Dejager, Claude Libert, Jan Tavernier, Ilse M. Beck & Karolien De Bosscher. (2013) How glucocorticoid receptors modulate the activity of other transcription factors: A scope beyond tethering. Molecular and Cellular Endocrinology 380:1-2, pages 41-54.
Crossref
Robert H. Oakley & John A. Cidlowski. (2013) The biology of the glucocorticoid receptor: New signaling mechanisms in health and disease. Journal of Allergy and Clinical Immunology 132:5, pages 1033-1044.
Crossref
Cristen B. Chafin, Nicole L. Regna, Sarah E. Hammond & Christopher M. Reilly. (2013) Cellular and urinary microRNA alterations in NZB/W mice with hydroxychloroquine or prednisone treatment. International Immunopharmacology 17:3, pages 894-906.
Crossref
Ingrid K. Bender, Yun Cao & Nick Z. Lu. (2013) Determinants of the Heightened Activity of Glucocorticoid Receptor Translational Isoforms. Molecular Endocrinology 27:9, pages 1577-1587.
Crossref
Josefine Lindroos, Julia Husa, Gerfried Mitterer, Arvand Haschemi, Sabine Rauscher, Robert Haas, Marion Gröger, Robert Loewe, Norbert Kohrgruber, Klaus F. Schrögendorfer, Gerhard Prager, Harald Beck, J. Andrew Pospisilik, Maximilian Zeyda, Thomas M. Stulnig, Wolfgang Patsch, Oswald Wagner, Harald Esterbauer & Martin Bilban. (2013) Human but Not Mouse Adipogenesis Is Critically Dependent on LMO3. Cell Metabolism 18:1, pages 62-74.
Crossref
Amanda Gruver-Yates & John Cidlowski. (2013) Tissue-Specific Actions of Glucocorticoids on Apoptosis: A Double-Edged Sword. Cells 2:2, pages 202-223.
Crossref
Yun Cao, Ingrid K. Bender, Athanasios K. Konstantinidis, Soon Cheon Shin, Christine M. Jewell, John A. Cidlowski, Robert P. Schleimer & Nick Z. Lu. (2013) Glucocorticoid receptor translational isoforms underlie maturational stage-specific glucocorticoid sensitivities of dendritic cells in mice and humans. Blood 121:9, pages 1553-1562.
Crossref
Steven Robertson, Janet P. Hapgood & Ann Louw. (2013) Glucocorticoid receptor concentration and the ability to dimerize influence nuclear translocation and distribution. Steroids 78:2, pages 182-194.
Crossref
I Wu, S C Shin, Y Cao, I K Bender, N Jafari, G Feng, S Lin, J A Cidlowski, R P Schleimer & N Z Lu. (2013) Selective glucocorticoid receptor translational isoforms reveal glucocorticoid-induced apoptotic transcriptomes. Cell Death & Disease 4:1, pages e453-e453.
Crossref
Yanyan Han, Claudia A. Staab-Weijnitz, Guangming Xiong & Edmund Maser. (2013) Identification of microRNAs as a potential novel regulatory mechanism in HSD11B1 expression. The Journal of Steroid Biochemistry and Molecular Biology 133, pages 129-139.
Crossref
Hui Li, Wenwei Qian, Xisheng Weng, Zhihong Wu, Huihua Li, Qianyu Zhuang, Bin Feng & Yanyan Bian. (2012) Glucocorticoid Receptor and Sequential P53 Activation by Dexamethasone Mediates Apoptosis and Cell Cycle Arrest of Osteoblastic MC3T3-E1 Cells. PLoS ONE 7:6, pages e37030.
Crossref
Paraskevi Moutsatsou, Eva Kassi & Athanasios G. Papavassiliou. (2012) Glucocorticoid receptor signaling in bone cells. Trends in Molecular Medicine 18:6, pages 348-359.
Crossref
Jih-Yang Ko, Re-Wen Wu, Shu-Jui Kuo, Ming-Wen Chen, Da-Wei Yeh, Huei-Ching Ke, Shin-Long Wu & Feng-Sheng Wang. (2012) Cannabinoid receptor 1 mediates glucocorticoid-induced bone loss in rats by perturbing bone mineral acquisition and marrow adipogenesis. Arthritis & Rheumatism 64:4, pages 1204-1214.
Crossref
Christine M. Jewell, Alyson B. Scoltock, Brant L. Hamel, Matthew R. Yudt & John A. Cidlowski. (2012) Complex Human Glucocorticoid Receptor dim Mutations Define Glucocorticoid Induced Apoptotic Resistance in Bone Cells. Molecular Endocrinology 26:2, pages 244-256.
Crossref
Re-Wen Wu, Tzu-Ping Lin, Jih-Yang Ko, Da-Wei Yeh, Ming-Wen Chen, Huei-Ching Ke, Shin-Long Wu & Feng-Sheng Wang. (2011) Cannabinoid receptor 1 regulates ERK and GSK-3β-dependent glucocorticoid inhibition of osteoblast differentiation in murine MC3T3-E1 cells. Bone 49:6, pages 1255-1263.
Crossref
George Schlossmacher, Adam Stevens & Anne White. (2011) Glucocorticoid receptor-mediated apoptosis: mechanisms of resistance in cancer cells. Journal of Endocrinology 211:1, pages 17-25.
Crossref
H. Gatica, M. Aliste, J. Guerrero & I. A. Goecke. (2011) Effects of methotrexate on the expression of the translational isoforms of glucocorticoid receptors   and  : correlation with methotrexate efficacy in rheumatoid arthritis patients. Rheumatology 50:9, pages 1665-1671.
Crossref
Katherine L. Gross, Robert H. Oakley, Alyson B. Scoltock, Christine M. Jewell & John A. Cidlowski. (2011) Glucocorticoid Receptor α Isoform-Selective Regulation of Antiapoptotic Genes in Osteosarcoma Cells: A New Mechanism for Glucocorticoid Resistance. Molecular Endocrinology 25:7, pages 1087-1099.
Crossref
Milan Surjit, Krishna Priya Ganti, Atish Mukherji, Tao Ye, Guoqiang Hua, Daniel Metzger, Mei Li & Pierre Chambon. (2011) Widespread Negative Response Elements Mediate Direct Repression by Agonist- Liganded Glucocorticoid Receptor. Cell 145:2, pages 224-241.
Crossref
Robert H. Oakley & John A. Cidlowski. (2011) Cellular Processing of the Glucocorticoid Receptor Gene and Protein: New Mechanisms for Generating Tissue-specific Actions of Glucocorticoids. Journal of Biological Chemistry 286:5, pages 3177-3184.
Crossref
Amy B. Emerman, Zai-Rong Zhang, Oishee Chakrabarti & Ramanujan S. Hegde. (2010) Compartment-Restricted Biotinylation Reveals Novel Features of Prion Protein Metabolism in Vivo. Molecular Biology of the Cell 21:24, pages 4325-4337.
Crossref
Jonathan D. Turner, Simone R. Alt, Lei Cao, Sara Vernocchi, Slavena Trifonova, Nadia Battello & Claude P. Muller. (2010) Transcriptional control of the glucocorticoid receptor: CpG islands, epigenetics and more. Biochemical Pharmacology 80:12, pages 1860-1868.
Crossref
Nelo Eidy Zanchi, Mário Alves de Siqueira Filho, Vitor Felitti, Humberto Nicastro, Fábio Medici Lorenzeti & Antonio Herbert LanchaJrJr. (2010) Glucocorticoids: Extensive physiological actions modulated through multiple mechanisms of gene regulation. Journal of Cellular Physiology 224:2, pages 311-315.
Crossref
Karolien De Bosscher. (2010) Selective Glucocorticoid Receptor modulators. The Journal of Steroid Biochemistry and Molecular Biology 120:2-3, pages 96-104.
Crossref
Stefano Bruscoli, Valerio Donato, Enrico Velardi, Moises Di Sante, Graziella Migliorati, Rosario Donato & Carlo Riccardi. (2010) Glucocorticoid-induced Leucine Zipper (GILZ) and Long GILZ Inhibit Myogenic Differentiation and Mediate Anti-myogenic Effects of Glucocorticoids. Journal of Biological Chemistry 285:14, pages 10385-10396.
Crossref
Claudia A. Staab & Edmund Maser. (2010) 11β-Hydroxysteroid dehydrogenase type 1 is an important regulator at the interface of obesity and inflammation. The Journal of Steroid Biochemistry and Molecular Biology 119:1-2, pages 56-72.
Crossref
Lindsay K. Smith & John A. Cidlowski. 2010. Neuroendocrinology - Pathological Situations and Diseases. Neuroendocrinology - Pathological Situations and Diseases 1 30 .
Robert H. Oakley, Laura J. Lewis-Tuffin, Carl D. Malchoff, Diana Mark Malchoff & John A. Cidlowski. 2010. Endocrinology. Endocrinology 1820 1830 .
Ilse M. E. Beck, Guy Haegeman & Karolien De Bosscher. 2010. From Molecular to Modular Tumor Therapy. From Molecular to Modular Tumor Therapy 191 242 .
Robert H. Oakley & John A. Cidlowski. 2010. Nuclear Receptors. Nuclear Receptors 63 89 .
Ilse M. E. Beck, Wim Vanden Berghe, Linda Vermeulen, Keith R. Yamamoto, Guy Haegeman & Karolien De Bosscher. (2009) Crosstalk in Inflammation: The Interplay of Glucocorticoid Receptor-Based Mechanisms and Kinases and Phosphatases. Endocrine Reviews 30:7, pages 830-882.
Crossref
Javier R. Revollo & John A. Cidlowski. (2009) Mechanisms Generating Diversity in Glucocorticoid Receptor Signaling. Annals of the New York Academy of Sciences 1179:1, pages 167-178.
Crossref
Amy J. Galliher-Beckley & John A. Cidlowski. (2009) Emerging roles of glucocorticoid receptor phosphorylation in modulating glucocorticoid hormone action in health and disease. IUBMB Life 61:10, pages 979-986.
Crossref
JOHN A. CIDLOWSKI. (2009) GLUCOCORTICOIDS AND THEIR ACTIONS IN CELLS. Retina 29:6, pages S21-S23.
Crossref
Erno Vreugdenhil, Carla S. L. Verissimo, Rob Mariman, Jessica T. Kamphorst, Joana S. Barbosa, Thijs Zweers, Danielle L. Champagne, Theo Schouten, Onno C. Meijer, E. Ron de Kloet & Carlos P. Fitzsimons. (2009) MicroRNA 18 and 124a Down-Regulate the Glucocorticoid Receptor: Implications for Glucocorticoid Responsiveness in the Brain. Endocrinology 150:5, pages 2220-2228.
Crossref
Katherine L. Gross, Nick Z. Lu & John A. Cidlowski. (2009) Molecular mechanisms regulating glucocorticoid sensitivity and resistance. Molecular and Cellular Endocrinology 300:1-2, pages 7-16.
Crossref
Paul E. Marik. (2009) Critical Illness-Related Corticosteroid Insufficiency. Chest 135:1, pages 181-193.
Crossref
P.J. Fuller & M.J. Young. 2009. Hormones, Brain and Behavior. Hormones, Brain and Behavior 1421 1439 .
Katherine L. Gross & John A. Cidlowski. (2008) Tissue-specific glucocorticoid action: a family affair. Trends in Endocrinology & Metabolism 19:9, pages 331-339.
Crossref

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