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Molecular and Cellular Biology Volume 32, 2012 - Issue 16
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Article

Calpain 2 Activated through N-Methyl-d-Aspartic Acid Receptor Signaling Cleaves CPEB3 and Abrogates CPEB3-Repressed Translation in Neurons

Chia-Fang Wanga Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan;b Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan
&
Yi-Shuian Huanga Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan;b Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, TaiwanCorrespondence[email protected]
Pages 3321-3332 | Received 04 Mar 2012, Accepted 08 Jun 2012, Published online: 20 Mar 2023

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Liang Hong, Han-Chang Huang & Zhao-Feng Jiang. (2014) Relationship between amyloid-beta and the ubiquitin–proteasome system in Alzheimer’s disease. Neurological Research 36:3, pages 276-282.
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Yi-Shuian Huang, Raul Mendez, Mercedes Fernandez & Joel D. Richter. (2023) CPEB and translational control by cytoplasmic polyadenylation: impact on synaptic plasticity, learning, and memory. Molecular Psychiatry.
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Jackie Ngai-Man Chan, Dalinda Isabel Sánchez-Vidaña, Shailendra Anoopkumar-Dukie, Yue Li & Lau Benson Wui-Man. (2022) RNA-binding protein signaling in adult neurogenesis. Frontiers in Cell and Developmental Biology 10.
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Yaping Liu, Runrong Ding, Ze Xu, Yuan Xue, Dongdong Zhang, Yujing Zhang, Wenjie Li & Xing Li. (2021) Roles and Mechanisms of the Protein Quality Control System in Alzheimer’s Disease. International Journal of Molecular Sciences 23:1, pages 345.
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Sara Picó, Alberto Parras, María Santos-Galindo, Julia Pose-Utrilla, Margarita Castro, Enrique Fraga, Ivó H. HernándezAinara Elorza, Héctor Anta, Nan WangLaura Martí-Sánchez, Eulàlia Belloc, Paula Garcia-Esparcia, Juan J. Garrido, Isidro Ferrer, Daniel Macías-García, Pablo Mir, Rafael Artuch, Belén PérezFélix HernándezPilar Navarro, José Luis López-Sendón, Teresa Iglesias, X. William YangRaúl Méndez & José J. Lucas. (2021) CPEB alteration and aberrant transcriptome-polyadenylation lead to a treatable SLC19A3 deficiency in Huntington’s disease. Science Translational Medicine 13:613.
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Wen-Hsin Lu, Hsu-Wen Chao, Pei-Yi Lin, Shu-Hui Lin, Tzu-Hsien Liu, Hao-Wen Chen & Yi-Shuian Huang. (2021) CPEB3-dowregulated Nr3c1 mRNA translation confers resilience to developing posttraumatic stress disorder-like behavior in fear-conditioned mice. Neuropsychopharmacology 46:9, pages 1669-1679.
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Wenrui Qu, Hongjuan Jin, Bing-Peng Chen, Jun Liu, Rui Li, Wenlai Guo & Heng Tian. (2020) CPEB3 regulates neuron-specific alternative splicing and involves neurogenesis gene expression. Aging 13:2, pages 2330-2347.
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Alessandro Evangelisti, Helen Butler & Federica del Monte. (2021) The Heart of the Alzheimer's: A Mindful View of Heart Disease. Frontiers in Physiology 11.
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Wen Rui Qu, Qi Han Sun, Qian Qian Liu, Hong Juan Jin, Ran Ji Cui, Wei Yang, De Biao Song & Bing Jin Li. (2020) Role of CPEB3 protein in learning and memory: new insights from synaptic plasticity. Aging 12:14, pages 15169-15182.
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Ronald Ng, Heather Manring, Nikolaos Papoutsidakis, Taylor Albertelli, Nicole Tsai, Claudia J. See, Xia Li, Jinkyu Park, Tyler L. Stevens, Prameela J. Bobbili, Muhammad Riaz, Yongming Ren, Christopher E. Stoddard, Paul M.L. Janssen, T. Jared Bunch, Stephen P. Hall, Ying-Chun Lo, Daniel L. Jacoby, Yibing Qyang, Nathan Wright, Maegen A. Ackermann & Stuart G. Campbell. (2019) Patient mutations linked to arrhythmogenic cardiomyopathy enhance calpain-mediated desmoplakin degradation. JCI Insight 4:14.
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I. V. Kudryashova. (2019) The Molecular Basis of Destabilization of Synapses as a Factor of Structural Plasticity. Neurochemical Journal 13:1, pages 1-10.
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Yubin Wang, Xiaoning Bi & Michel Baudry. 2018. Acute Neuronal Injury. Acute Neuronal Injury 19 35 .
Ching-San Tseng, Hsu-Wen Chao, Hsien-Sung Huang & Yi-Shuian Huang. (2017) Olfactory-Experience- and Developmental-Stage-Dependent Control of CPEB4 Regulates c-Fos mRNA Translation for Granule Cell Survival. Cell Reports 21:8, pages 2264-2276.
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Jie Liang, Jia-Li Li, Ying Han, Yi-Xiao Luo, Yan-Xue Xue, Yàn Zhang, Yán Zhang, Li-Bo Zhang, Man-Li Chen, Lin Lu & Jie Shi. (2017) Calpain-GRIP Signaling in Nucleus Accumbens Core Mediates the Reconsolidation of Drug Reward Memory. The Journal of Neuroscience 37:37, pages 8938-8951.
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Victor Briz & Michel Baudry. (2016) Calpains: Master Regulators of Synaptic Plasticity. The Neuroscientist 23:3, pages 221-231.
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Judit Faus-Garriga, Isabel Novoa & Andrés Ozaita. (2017) mTOR signaling in proteostasis and its relevance to autism spectrum disorders. AIMS Biophysics 4:1, pages 63-89.
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Andrej Susor & Michal Kubelka. 2017. Oocytes. Oocytes 257 295 .
Yin-Peng Chen, Geng-Shuo Bai, Meng-Fang Wu, Chuan-Chin Chiao & Yi-Shuian Huang. (2016) Loss of CPEB3 Upregulates MEGF10 to Impair Mosaic Development of ON Starburst Amacrine Cells. Frontiers in Molecular Neuroscience 9.
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Iaroslav Savtchouk, Lu Sun, Crhistian L. Bender, Qian Yang, Gábor Szabó, Sonia Gasparini & Siqiong June Liu. (2016) Topological Regulation of Synaptic AMPA Receptor Expression by the RNA-Binding Protein CPEB3. Cell Reports 17:1, pages 86-103.
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Michele Curcio, Ivan L. Salazar, Miranda Mele, Lorella M.T. Canzoniero & Carlos B. Duarte. (2016) Calpains and neuronal damage in the ischemic brain: The swiss knife in synaptic injury. Progress in Neurobiology 143, pages 1-35.
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Sitt Wai Fong, Hsiu-Chen Lin, Meng-Fang Wu, Chih-Cheng Chen & Yi-Shuian Huang. (2016) CPEB3 Deficiency Elevates TRPV1 Expression in Dorsal Root Ganglia Neurons to Potentiate Thermosensation. PLOS ONE 11:2, pages e0148491.
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Chen-Dan Zou, Wei-Ming Zhao, Xiao-Na Wang, Qiang Li, Hui Huang, Wan-Peng Cheng, Jian-Feng Jin, He Zhang, Ming-Juan Wu, Sheng Tai, Chao-Xia Zou & Xu Gao. (2015) MicroRNA-107: a novel promoter of tumor progression that targets the CPEB3/EGFR axis in human hepatocellular carcinoma. Oncotarget 7:1, pages 266-278.
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Yuko Fukunaga, Eri Nakajima, Erika Hatano, Sayaka Itoh, Yasuhiro Kashino & Atsuo Miyazawa. (2015) Activation of NMDA receptors thickens the postsynaptic density via proteolysis. Neuroscience Research 101, pages 6-14.
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Po-Jen Chen, Jui-Yun Weng, Pang-Hung Hsu, Jin-Yuh Shew, Yi-Shuian Huang & Wen-Hwa Lee. (2015) NPGPx modulates CPEB2-controlled HIF-1α RNA translation in response to oxidative stress. Nucleic Acids Research 43:19, pages 9393-9404.
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Hui-Yan Lei, Xiao-Long Zhou, Zhi-Rong Ruan, Wei-Cheng Sun, Gilbert Eriani & En-Duo Wang. (2015) Calpain Cleaves Most Components in the Multiple Aminoacyl-tRNA Synthetase Complex and Affects Their Functions. Journal of Biological Chemistry 290:43, pages 26314-26327.
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Wen-Hsuan Huang, Hsu-Wen Chao, Li-Yun Tsai, Ming-Hung Chung & Yi-Shuian Huang. (2014) Elevated activation of CaMKIIα in the CPEB3-knockout hippocampus impairs a specific form of NMDAR-dependent synaptic depotentiation. Frontiers in Cellular Neuroscience 8.
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Yu-Wei Chang & Yi-Shuian Huang. (2014) Arsenite-Activated JNK Signaling Enhances CPEB4-Vinexin Interaction to Facilitate Stress Granule Assembly and Cell Survival. PLoS ONE 9:9, pages e107961.
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Li-Yun Tsai, Yu-Wei Chang, Pei-Yi Lin, Hsin-Jung Chou, Ta-Jen Liu, Ping-Tao Lee, Wen-Hsuan Huang, Yueh-Liang Tsou & Yi-Shuian Huang. (2013) CPEB4 Knockout Mice Exhibit Normal Hippocampus-Related Synaptic Plasticity and Memory. PLoS ONE 8:12, pages e84978.
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Yubin Wang, Victor Briz, Athar Chishti, Xiaoning Bi & Michel Baudry. (2013) Distinct Roles for μ-Calpain and m-Calpain in Synaptic NMDAR-Mediated Neuroprotection and Extrasynaptic NMDAR-Mediated Neurodegeneration. The Journal of Neuroscience 33:48, pages 18880-18892.
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Hsu-Wen Chao, Li-Yun Tsai, Yi-Ling Lu, Pei-Yi Lin, Wen-Hsuan Huang, Hsin-Jung Chou, Wen-Hsin Lu, Hsiu-Chen Lin, Ping-Tao Lee & Yi-Shuian Huang. (2013) Deletion of CPEB3 Enhances Hippocampus-Dependent Memory via Increasing Expressions of PSD95 and NMDA Receptors. The Journal of Neuroscience 33:43, pages 17008-17022.
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Amanda Charlesworth, Hedda A. Meijer & Cornelia H. de Moor. (2013) Specificity factors in cytoplasmic polyadenylation. Wiley Interdisciplinary Reviews: RNA 4:4, pages 437-461.
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Wei Cui, Jie Ma, Xingqin Wang, Wenjuan Yang, Jing Zhang & Qiuhe Ji. (2013) Free Fatty Acid Induces Endoplasmic Reticulum Stress and Apoptosis of β-cells by Ca2+/Calpain-2 Pathways. PLoS ONE 8:3, pages e59921.
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Aparna Oruganty-Das, Teclise Ng, Tsuyoshi Udagawa, Eyleen L.K. Goh & Joel D. Richter. (2012) Translational Control of Mitochondrial Energy Production Mediates Neuron Morphogenesis. Cell Metabolism 16:6, pages 789-800.
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