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Molecular and Cellular Biology Volume 40, 2020 - Issue 2
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Research Article

The SOX9-Aldehyde Dehydrogenase Axis Determines Resistance to Chemotherapy in Non-Small-Cell Lung Cancer

Maria A. Voronkovaa West Virginia University Cancer Institute, West Virginia University, Morgantown, West Virginia, USA
,
Liying W. Rojanasakulb Allergy and Clinical Immunology Branch, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA
,
Chayanin Kiratipaiboonc Department of Pharmaceutical Sciences, West Virginia University, Morgantown, West Virginia, USA
&
Yon Rojanasakula West Virginia University Cancer Institute, West Virginia University, Morgantown, West Virginia, USA;c Department of Pharmaceutical Sciences, West Virginia University, Morgantown, West Virginia, USACorrespondence[email protected]
Article: e00307-19 | Received 16 Jul 2019, Accepted 22 Oct 2019, Published online: 03 Mar 2023

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Jiang-Jie Duan, Jiao Cai, Lei Gao & Shi-Cang Yu. (2023) ALDEFLUOR activity, ALDH isoforms, and their clinical significance in cancers. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Articles from other publishers (22)

Lidan Zeng, Yueming Zhu, Carlos S. Moreno & Yong Wan. (2023) New insights into KLFs and SOXs in cancer pathogenesis, stemness, and therapy. Seminars in Cancer Biology 90, pages 29-44.
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Salma A. Al-Shamma, Dana M. Zaher, Fatema Hersi, Nour N. Abu Jayab & Hany A. Omar. (2023) Targeting aldehyde dehydrogenase enzymes in combination with chemotherapy and immunotherapy: An approach to tackle resistance in cancer cells. Life Sciences 320, pages 121541.
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Yaolu Wei, Yan Li, Yenan Chen, Pei Liu, Sheng Huang, Yuping Zhang, Yanling Sun, Zhe Wu, Meichun Hu, Qian Wu, Hongnian Wu, Fuxing Liu, Tonghui She & Zhifeng Ning. (2022) ALDH1: A potential therapeutic target for cancer stem cells in solid tumors. Frontiers in Oncology 12.
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Huafeng Liu, Liting Zhong, Yanjun Lu, Xuewen Liu, Jiawang Wei, Yuhai Ding, Huiling Huang, Qihong Nie & Xiaohong Liao. (2022) Deubiquitylase OTUD1 confers Erlotinib sensitivity in non-small cell lung cancer through inhibition of nuclear translocation of YAP1. Cell Death Discovery 8:1.
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Surya Kant Tripathi, Rajeev Kumar Sahoo & Bijesh Kumar Biswal. (2022) SOX9 as an emerging target for anticancer drugs and a prognostic biomarker for cancer drug resistance. Drug Discovery Today 27:9, pages 2541-2550.
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Huan Chen, Xupeng Chen, Fanhua Zeng, Aizhen Fu & Meiyuan Huang. (2022) Prognostic value of SOX9 in cervical cancer: Bioinformatics and experimental approaches. Frontiers in Genetics 13.
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Mijung Oh, Chaeyeon Son, Seung Bae Rho, Minjeong Kim, Kyoungsook Park & Sang Yong Song. (2022) Stem Cell Factor SOX9 Interacts with a Cell Death Regulator RIPK1 and Results in Escape of Cancer Stem Cell Death. Cells 11:3, pages 363.
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Lourdes Cortes-Dericks & Domenico Galetta. (2022) Impact of Cancer Stem Cells and Cancer Stem Cell-Driven Drug Resiliency in Lung Tumor: Options in Sight. Cancers 14:2, pages 267.
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Yajie ShenJingqi Zhou, Kui NieShuhua ChengZhengming ChenWenhan WangWeiqing Wei, Daiji JiangZijing PengYizhuo RenYirong Zhang, Qiuju FanKristy L. Richards, Yitao QiJinke Cheng, Wayne Tam & Jiao Ma. (2022) Oncogenic role of the SOX9-DHCR24-cholesterol biosynthesis axis in IGH-BCL2 + diffuse large B-cell lymphomas . Blood 139:1, pages 73-86.
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Zhi-Fu Li, Dong-Dong Meng, Yong-Yi Liu, Fang-Gang Bi, Ke Tian, Jian-Zhong Xu, Jian-Guang Sun, Chen-Xi Gu & Yu Li. (2022) Hypoxia inducible factor-3α promotes osteosarcoma progression by activating KDM3A-mediated demethylation of SOX9. Chemico-Biological Interactions 351, pages 109759.
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Tianyu Sun, Jingge Zhang, Xiaoqing Fan, Tan Long, Shaolin Tao, Poming Kang & Qunyou Tan. (2021) The Human Positive Cofactor 4 is a Promising Chemotherapeutic Target in Lung Adenocarcinoma. Journal of Oncology 2021, pages 1-13.
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Aihua Ji, Lei Qian, Zhenmin Tian & Jie Cui. (2021) WDR5 promotes the proliferation of lung adenocarcinoma by inducing SOX9 expression. Biomarkers in Medicine 15:17, pages 1599-1609.
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Mario Cioce, Claudia Canino, Harvey Pass, Giovanni Blandino, Sabrina Strano & Vito Michele Fazio. (2021) Arachidonic acid drives adaptive responses to chemotherapy-induced stress in malignant mesothelioma. Journal of Experimental & Clinical Cancer Research 40:1.
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Mario Cioce, Andrea Sacconi, Harvey I. Pass, Claudia Canino, Sabrina Strano, Giovanni Blandino & Vito Michele Fazio. (2021) Insights into Intra-Tumoral Heterogeneity: Transcriptional Profiling of Chemoresistant MPM Cell Subpopulations Reveals Involvement of NFkB and DNA Repair Pathways and Contributes a Prognostic Signature. International Journal of Molecular Sciences 22:21, pages 12071.
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Hong Yang, Yiwen Liu & Jinyu Kong. (2021) Effect of aerobic exercise on acquired gefitinib resistance in lung adenocarcinoma. Translational Oncology 14:11, pages 101204.
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Munmun Panda, Surya Kant Tripathi & Bijesh K. Biswal. (2021) SOX9: An emerging driving factor from cancer progression to drug resistance. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1875:2, pages 188517.
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Shengyu Cui, Zhebo Liu, Bo Tao, Suzhen Fan, Yong Pu, Xiangping Meng, Dongqing Li, Hao Xia & Lin Xu. (2020) miR‐145 attenuates cardiac fibrosis through the AKT/GSK‐3β/β‐catenin signaling pathway by directly targeting SOX9 in fibroblasts. Journal of Cellular Biochemistry 122:2, pages 209-221.
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Huijie Fan, Jing Yuan, Yaqing Li, Yongxu Jia, Jing Li, Xiaofeng Wang & Xingya Li. (2021) MKL1-induced lncRNA SNHG18 drives the growth and metastasis of non-small cell lung cancer via the miR-211-5p/BRD4 axis. Cell Death & Disease 12:1.
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Jolanta Szenajch, Alicja Szabelska-Beręsewicz, Aleksandra Świercz, Joanna Zyprych-Walczak, Idzi Siatkowski, Michał Góralski, Agnieszka Synowiec & Luiza Handschuh. (2020) Transcriptome Remodeling in Gradual Development of Inverse Resistance between Paclitaxel and Cisplatin in Ovarian Cancer Cells. International Journal of Molecular Sciences 21:23, pages 9218.
Crossref
Miguel Ángel Sarabia-Sánchez, Eduardo Alvarado-Ortiz, Mariel Esperanza Toledo-Guzman, Alejandro García-Carrancá & Elizabeth Ortiz-Sánchez. (2020) ALDHHIGH Population Is Regulated by the AKT/β-Catenin Pathway in a Cervical Cancer Model. Frontiers in Oncology 10.
Crossref
Davide M. Ferraris, Edoardo L. M. Gelardi, Silvia Garavaglia, Riccardo Miggiano & Menico Rizzi. (2020) Targeting NAD-dependent dehydrogenases in drug discovery against infectious diseases and cancer. Biochemical Society Transactions 48:2, pages 693-707.
Crossref
Li Liu, Lu Yan, Ning Liao, Wan-Qin Wu & Jun-Ling Shi. (2020) A Review of ULK1-Mediated Autophagy in Drug Resistance of Cancer. Cancers 12:2, pages 352.
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