23
Views
79
CrossRef citations to date
0
Altmetric
Article

A Novel Cyclic AMP-Dependent Epac-Rit Signaling Pathway Contributes to PACAP38-Mediated Neuronal Differentiation

, &
Pages 9136-9147 | Received 23 Feb 2006, Accepted 06 Sep 2006, Published online: 27 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Weikang Cai, Geng-Xian Shi & Douglas A. Andres. (2013) Putting the Rit in cellular resistance. Communicative & Integrative Biology 6:1.
Read now
Geng-Xian Shi, Ling Jin & Douglas A. Andres. (2011) A Rit GTPase-p38 Mitogen-Activated Protein Kinase Survival Pathway Confers Resistance to Cellular Stress. Molecular and Cellular Biology 31:10, pages 1938-1948.
Read now
Chang Liu, Maho Takahashi, Yanping Li, Shuang Song, Tara J. Dillon, Ujwal Shinde & Philip J. S. Stork. (2008) Ras Is Required for the Cyclic AMP-Dependent Activation of Rap1 via Epac2. Molecular and Cellular Biology 28:23, pages 7109-7125.
Read now
Rasmus Koefoed Petersen, Lise Madsen, Lone Møller Pedersen, Philip Hallenborg, Hanne Hagland, Kristin Viste, Stein Ove Døskeland & Karsten Kristiansen. (2008) Cyclic AMP (cAMP)-Mediated Stimulation of Adipocyte Differentiation Requires the Synergistic Action of Epac- and cAMP-Dependent Protein Kinase-Dependent Processes. Molecular and Cellular Biology 28:11, pages 3804-3816.
Read now

Articles from other publishers (74)

Hasan Slika, Hadi Mansour, Suzanne A. Nasser, Abdullah Shaito, Firas Kobeissy, Alexander N. Orekhov, Gianfranco Pintus & Ali H. Eid. (2023) Epac as a tractable therapeutic target. European Journal of Pharmacology 945, pages 175645.
Crossref
Jing An, Bo Chen, Ding Tian, Yunshan Guo, Yuzhu Yan & Hao Yang. (2022) Regulation of Neurogenesis and Neuronal Differentiation by Natural Compounds. Current Stem Cell Research & Therapy 17:8, pages 756-771.
Crossref
Ahmed Maher, Nesrine El Sayed, Heba Nafea & Mohamed Gad. (2022) Rolipram Rescues Memory Consolidation Deficits Caused by Sleep Deprivation: Implication of the cAMP/PKA and cAMP/Epac Pathways. CNS & Neurological Disorders - Drug Targets 21:7, pages 631-639.
Crossref
Jessica Lu, Sarah J. Piper, Peishen Zhao, Laurence J. Miller, Denise Wootten & Patrick M. Sexton. (2022) Targeting VIP and PACAP Receptor Signaling: New Insights into Designing Drugs for the PACAP Subfamily of Receptors. International Journal of Molecular Sciences 23:15, pages 8069.
Crossref
Muhammad Bilal Ahmed, Abdullah A. A. Alghamdi, Salman Ul Islam, Joon-Seok Lee & Young-Sup Lee. (2022) cAMP Signaling in Cancer: A PKA-CREB and EPAC-Centric Approach. Cells 11:13, pages 2020.
Crossref
Zhengyin Gao, Weng I Lei & Leo Tsz On Lee. (2022) The Role of Neuropeptide-Stimulated cAMP-EPACs Signalling in Cancer Cells. Molecules 27:1, pages 311.
Crossref
Kyungmin Lee. (2021) Epac: new emerging cAMP-binding protein. BMB Reports 54:3, pages 149-156.
Crossref
Marion Laudette, Karina Formoso & Frank Lezoualc’h. (2021) GRKs and Epac1 Interaction in Cardiac Remodeling and Heart Failure. Cells 10:1, pages 154.
Crossref
Nadine Wehbe, Hasan Slika, Joelle Mesmar, Suzanne A. Nasser, Gianfranco Pintus, Serine Baydoun, Adnan Badran, Firas Kobeissy, Ali H. Eid & Elias Baydoun. (2020) The Role of Epac in Cancer Progression. International Journal of Molecular Sciences 21:18, pages 6489.
Crossref
Richard VanAntonio Cuevas-Navarro, Pau Castel & Frank McCormick. (2020) The molecular functions of RIT1 and its contribution to human disease. Biochemical Journal 477:15, pages 2755-2770.
Crossref
Rudy Schreiber, Romain Hollands & Arjan Blokland. (2020) A Mechanistic Rationale for PDE-4 Inhibitors to Treat Residual Cognitive Deficits in Acquired Brain Injury. Current Neuropharmacology 18:3, pages 188-201.
Crossref
Masaki Hara, Yuko Takeba, Taroh Iiri, Yuki Ohta, Masanori Ootaki, Minoru Watanabe, Daiki Watanabe, Satoshi Koizumi, Takehito Otsubo & Naoki Matsumoto. (2019) Vasoactive intestinal peptide increases apoptosis of hepatocellular carcinoma by inhibiting the cAMP/Bcl-xL pathway. Cancer Science 110:1, pages 235-244.
Crossref
Tahlia Sundrum & Christopher S Walker. (2018) Pituitary adenylate cyclase-activating polypeptide receptors in the trigeminovascular system: implications for migraine. British Journal of Pharmacology 175:21, pages 4109-4120.
Crossref
Uta Meyer zum Büschenfelde, Laura Isabel Brandenstein, Leonie von Elsner, Kristina Flato, Tess Holling, Martin Zenker, Georg Rosenberger & Kerstin Kutsche. (2018) RIT1 controls actin dynamics via complex formation with RAC1/CDC42 and PAK1. PLOS Genetics 14:5, pages e1007370.
Crossref
William G. RobichauxIIIIII & Xiaodong Cheng. (2018) Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development. Physiological Reviews 98:2, pages 919-1053.
Crossref
Wei-Peng Li, Ke Ma, Xiao-Yan Jiang, Rui Yang, Pei-Hua Lu, Bao-Ming Nie & Yang Lu. (2018) Molecular mechanism of panaxydol on promoting axonal growth in PC12 cells. Neural Regeneration Research 13:11, pages 1927.
Crossref
Eric R. Starr & Joseph F. Margiotta. (2017) Pituitary adenylate cyclase activating polypeptide induces long-term, transcription-dependent plasticity and remodeling at autonomic synapses. Molecular and Cellular Neuroscience 85, pages 170-182.
Crossref
Andrew C. Emery, Wenqin Xu, Maribeth V. Eiden & Lee E. Eiden. (2017) Guanine nucleotide exchange factor Epac2–dependent activation of the GTP-binding protein Rap2A mediates cAMP-dependent growth arrest in neuroendocrine cells. Journal of Biological Chemistry 292:29, pages 12220-12231.
Crossref
I. F. Sukhanova, L. M. Kozhevnikova, G. Yu. Mironova & P. V. Avdonin. (2017) The Epac protein inhibitor ESI-09 eliminates the tonic phase of aorta contraction induced by endogenic vasoconstrictors in rats. Biology Bulletin 44:2, pages 179-186.
Crossref
Pablo Muñoz-Llancao, Cristian de Gregorio, Macarena Las Heras, Christopher Meinohl, Kevin Noorman, Erik Boddeke, Xiaodong Cheng, Frank Lezoualc'h, Martina Schmidt & Christian Gonzalez-Billault. (2017) Microtubule-regulating proteins and cAMP-dependent signaling in neuroblastoma differentiation. Cytoskeleton 74:3, pages 143-158.
Crossref
Faiza Baameur, Pooja Singhmar, Yong Zhou, John F. Hancock, Xiaodong Cheng, Cobi J. Heijnen & Annemieke Kavelaars. (2016) Epac1 interacts with importin β1 and controls neurite outgrowth independently of cAMP and Rap1. Scientific Reports 6:1.
Crossref
L Zhou, S L Ma, P K K Yeung, Y H Wong, K W K Tsim, K F So, L C W Lam & S K Chung. (2016) Anxiety and depression with neurogenesis defects in exchange protein directly activated by cAMP 2-deficient mice are ameliorated by a selective serotonin reuptake inhibitor, Prozac. Translational Psychiatry 6:9, pages e881-e881.
Crossref
Zhenhao Fang, Christopher B. Marshall, Jiani C. Yin, Mohammad T. Mazhab-Jafari, Geneviève M.C. Gasmi-Seabrook, Matthew J. Smith, Tadateru Nishikawa, Yang Xu, Benjamin G. Neel & Mitsuhiko Ikura. (2016) Biochemical Classification of Disease-associated Mutants of RAS-like Protein Expressed in Many Tissues (RIT1). Journal of Biological Chemistry 291:30, pages 15641-15652.
Crossref
Todd A. Clason, Beatrice M. Girard, Victor May & Rodney L. Parsons. (2016) Activation of MEK/ERK Signaling by PACAP in Guinea Pig Cardiac Neurons. Journal of Molecular Neuroscience 59:2, pages 309-316.
Crossref
Zhiwen Zhou, Kenji F. Tanaka, Shigeru Matsunaga, Mineo Iseki, Masakatsu Watanabe, Norio Matsuki, Yuji Ikegaya & Ryuta Koyama. (2016) Photoactivated adenylyl cyclase (PAC) reveals novel mechanisms underlying cAMP-dependent axonal morphogenesis. Scientific Reports 6:1.
Crossref
Karl Blirando, Régis Blaise, Natalia Gorodnaya, Clotilde Rouxel, Olivier Meilhac, Pierre Vincent & Isabelle Limon. (2015) The stellate vascular smooth muscle cell phenotype is induced by IL-1β via the secretion of PGE2 and subsequent cAMP-dependent protein kinase A activation. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1853:12, pages 3235-3247.
Crossref
A H Berger, M Imielinski, F Duke, J Wala, N Kaplan, G-X Shi, D A Andres & M Meyerson. (2014) Oncogenic RIT1 mutations in lung adenocarcinoma. Oncogene 33:35, pages 4418-4423.
Crossref
Thota Ganesh. (2013) Prostanoid Receptor EP2 as a Therapeutic Target. Journal of Medicinal Chemistry 57:11, pages 4454-4465.
Crossref
Andrew C. Emery, Maribeth V. Eiden & Lee E. Eiden. (2014) Separate Cyclic AMP Sensors for Neuritogenesis, Growth Arrest, and Survival of Neuroendocrine Cells. Journal of Biological Chemistry 289:14, pages 10126-10139.
Crossref
E. Vitali, E. Peverelli, E. Giardino, M. Locatelli, G.B. Lasio, P. Beck-Peccoz, A. Spada, A.G. Lania & G. Mantovani. (2014) Cyclic adenosine 3′-5′-monophosphate (cAMP) exerts proliferative and anti-proliferative effects in pituitary cells of different types by activating both cAMP-dependent protein kinase A (PKA) and exchange proteins directly activated by cAMP (Epac). Molecular and Cellular Endocrinology 383:1-2, pages 193-202.
Crossref
Miguel Perez‐Aso, Patricia Fernandez, Aránzazu Mediero, Edwin S. Chan & Bruce N. Cronstein. (2013) Adenosine 2A receptor promotes collagen production by human fibroblasts via pathways involving cyclic AMP and AKT but independent of Smad2/3 . The FASEB Journal 28:2, pages 802-812.
Crossref
Geng-Xian Shi & Catherine N. Kaminski. 2014. Ras Signaling. Ras Signaling 217 240 .
Ruth D.T. Taylor, Marita Grønning Madsen, Michael Krause, Marisol Sampedro‐Castañeda, Martin Stocker & Paola Pedarzani. (2013) Pituitary adenylate cyclase‐activating polypeptide (PACAP) inhibits the slow afterhyperpolarizing current sI AHP in CA1 pyramidal neurons by activating multiple signaling pathways . Hippocampus 24:1, pages 32-43.
Crossref
Yin-zhong Ma, Na Ning, Wen-bin He, Jing-wei Li, Jin-feng Hu, Shi-feng Chu & Nai-hong Chen. (2013) Claulansine F promotes neuritogenesis in PC12 cells via the ERK signaling pathway. Acta Pharmacologica Sinica 34:12, pages 1499-1507.
Crossref
Geng-Xian Shi, Weikang Cai & Douglas A. Andres. (2013) Rit subfamily small GTPases: Regulators in neuronal differentiation and survival. Cellular Signalling 25:10, pages 2060-2068.
Crossref
Jianxiong Jiang & Ray Dingledine. (2013) Prostaglandin receptor EP2 in the crosshairs of anti-inflammation, anti-cancer, and neuroprotection. Trends in Pharmacological Sciences 34:7, pages 413-423.
Crossref
Martina Schmidt, Frank J. Dekker & Harm Maarsingh. (2013) Exchange Protein Directly Activated by cAMP (epac): A Multidomain cAMP Mediator in the Regulation of Diverse Biological Functions. Pharmacological Reviews 65:2, pages 670-709.
Crossref
Geng-Xian Shi, Weikang Cai & Douglas A. Andres. (2012) Rit-mediated Stress Resistance Involves a p38-Mitogen- and Stress-activated Protein Kinase 1 (MSK1)-dependent cAMP Response Element-binding Protein (CREB) Activation Cascade. Journal of Biological Chemistry 287:47, pages 39859-39868.
Crossref
Anne-Coline Laurent, Magali Breckler, Magali Berthouze & Frank Lezoualc'h. (2012) Role of Epac in brain and heart. Biochemical Society Transactions 40:1, pages 51-57.
Crossref
Guoqiang Wan, Lihan Zhou, Qing 'En Lim, Yung Hou Wong & Heng-Phon Too. (2011) Cyclic AMP signalling through PKA but not Epac is essential for neurturin-induced biphasic ERK1/2 activation and neurite outgrowths through GFRα2 isoforms. Cellular Signalling 23:11, pages 1727-1737.
Crossref
Weikang Cai, Jennifer L. Rudolph, Susan M. W. Harrison, Ling Jin, Aubrey L. Frantz, Douglas A. Harrison & Douglas A. Andres. (2011) An evolutionarily conserved Rit GTPase–p38 MAPK signaling pathway mediates oxidative stress resistance. Molecular Biology of the Cell 22:17, pages 3231-3241.
Crossref
Magali Breckler, Magali Berthouze, Anne-Coline Laurent, Bertrand Crozatier, Eric Morel & Frank Lezoualc'h. (2011) Rap-linked cAMP signaling Epac proteins: Compartmentation, functioning and disease implications. Cellular Signalling 23:8, pages 1257-1266.
Crossref
Wei Cui, Guo-Zhen Cui, Wenming Li, Zaijun Zhang, Shengquan Hu, Shinghung Mak, Huan Zhang, Paul R. Carlier, Chung-lit Choi, Yi-Tao Wong, Simon Ming-Yuen Lee & Yifan Han. (2011) Bis(12)-hupyridone, a novel multifunctional dimer, promotes neuronal differentiation more potently than its monomeric natural analog huperzine A possibly through alpha7 nAChR. Brain Research 1401, pages 10-17.
Crossref
Bartosz J. Zieba, Mykhaylo V. Artamonov, Li Jin, Ko Momotani, Ruoya Ho, Aaron S. Franke, Ronald L. Neppl, Andra S. Stevenson, Alexander S. Khromov, Magdalena Chrzanowska-Wodnicka & Avril V. Somlyo. (2011) The cAMP-responsive Rap1 Guanine Nucleotide Exchange Factor, Epac, Induces Smooth Muscle Relaxation by Down-regulation of RhoA Activity. Journal of Biological Chemistry 286:19, pages 16681-16692.
Crossref
Richard C. Hewer, Graciela B. Sala-Newby, Yih-Jer Wu, Andrew C. Newby & Mark Bond. (2011) PKA and Epac synergistically inhibit smooth muscle cell proliferation. Journal of Molecular and Cellular Cardiology 50:1, pages 87-98.
Crossref
Mélanie Métrich, Anne-Coline Laurent, Magali Breckler, Nicolas Duquesnes, Isabelle Hmitou, Delphine Courillau, Jean-Paul Blondeau, Bertrand Crozatier, Frank Lezoualc'h & Eric Morel. (2010) Epac activation induces histone deacetylase nuclear export via a Ras-dependent signalling pathway. Cellular Signalling 22:10, pages 1459-1468.
Crossref
Nicolas Duquesnes, Mickael Derangeon, Mélanie Métrich, Alexandre Lucas, Philippe Mateo, Lin Li, Eric Morel, Frank Lezoualc’h & Bertrand Crozatier. (2010) Epac stimulation induces rapid increases in connexin43 phosphorylation and function without preconditioning effect. Pflügers Archiv - European Journal of Physiology 460:4, pages 731-741.
Crossref
Dirk Haubert & Gisbert Weckbecker. (2010) Vav1 couples the T cell receptor to cAMP response element activation via a PKC-dependent pathway. Cellular Signalling 22:6, pages 944-954.
Crossref
Geng-Xian Shi, Ling Jin & Douglas A. Andres. (2010) Src-dependent TrkA Transactivation Is Required for Pituitary Adenylate Cyclase-activating Polypeptide 38-mediated Rit Activation and Neuronal Differentiation. Molecular Biology of the Cell 21:9, pages 1597-1608.
Crossref
Patrick Kelly, Candice L. Bailey, Patrick T. Fueger, Christopher B. Newgard, Patrick J. Casey & Michelle E. Kimple. (2010) Rap1 Promotes Multiple Pancreatic Islet Cell Functions and Signals through Mammalian Target of Rapamycin Complex 1 to Enhance Proliferation. Journal of Biological Chemistry 285:21, pages 15777-15785.
Crossref
Martijn GloerichJohannes L. Bos. (2010) Epac: Defining a New Mechanism for cAMP Action. Annual Review of Pharmacology and Toxicology 50:1, pages 355-375.
Crossref
Gillian Borland, Brian O Smith & Stephen J Yarwood. (2009) EPAC proteins transduce diverse cellular actions of cAMP. British Journal of Pharmacology 158:1, pages 70-86.
Crossref
Pierre Voisin & Marianne Bernard. (2009) Cyclic AMP-dependent activation of rhodopsin gene transcription in cultured retinal precursor cells of chicken embryo. Journal of Neurochemistry 110:1, pages 318-327.
Crossref
Tatiana Fila, Stefania Trazzi, Christophe Crochemore, Renata Bartesaghi & Elisabetta Ciani. (2009) Lot1 Is a Key Element of the Pituitary Adenylate Cyclase-activating Polypeptide (PACAP)/Cyclic AMP Pathway That Negatively Regulates Neuronal Precursor Proliferation. Journal of Biological Chemistry 284:22, pages 15325-15338.
Crossref
Douglas A. Andres, Geng-Xian Shi, Donald Bruun, Chris Barnhart & Pamela J. Lein. (2008) Rit signaling contributes to interferon-γ-induced dendritic retraction via p38 mitogen-activated protein kinase activation. Journal of Neurochemistry 107:5, pages 1436-1447.
Crossref
Hege Ugland, Andrew C. Boquest, Soheil Naderi, Philippe Collas & Heidi Kiil Blomhoff. (2008) cAMP-mediated Induction of Cyclin E Sensitizes Growth-arrested Adipose Stem Cells to DNA Damage–induced Apoptosis. Molecular Biology of the Cell 19:12, pages 5082-5092.
Crossref
Naoko Tomimatsu & Yoshihiro Arakawa. (2008) Survival-promoting activity of pituitary adenylate cyclase-activating polypeptide in the presence of phosphodiesterase inhibitors on rat motoneurons in culture: cAMP-protein kinase A-mediated survival. Journal of Neurochemistry 107:3, pages 628-635.
Crossref
Adriane D. Sumner & Joseph F. Margiotta. (2008) Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Alters Parasympathetic Neuron Gene Expression in a Time-dependent Fashion. Journal of Molecular Neuroscience 36:1-3, pages 141-156.
Crossref
Agnieszka Dejda, Valérie Jolivel, Steve Bourgault, Tommy Seaborn, Alain Fournier, Hubert Vaudry & David Vaudry. (2008) Inhibitory Effect of PACAP on Caspase Activity in Neuronal Apoptosis: A Better Understanding Towards Therapeutic Applications in Neurodegenerative Diseases. Journal of Molecular Neuroscience 36:1-3, pages 26-37.
Crossref
Nancy Gerits, Sergiy Kostenko, Alexey Shiryaev, Mona Johannessen & Ugo Moens. (2008) Relations between the mitogen-activated protein kinase and the cAMP-dependent protein kinase pathways: Comradeship and hostility. Cellular Signalling 20:9, pages 1592-1607.
Crossref
Andrew J. Murray & Derryck A. Shewan. (2008) Epac mediates cyclic AMP-dependent axon growth, guidance and regeneration. Molecular and Cellular Neuroscience 38:4, pages 578-588.
Crossref
Xiaodong Cheng, Zhenyu Ji, Tamara Tsalkova & Fang Mei. (2008) Epac and PKA: a tale of two intracellular cAMP receptors. Acta Biochimica et Biophysica Sinica 40:7, pages 651-662.
Crossref
Sara S. Roscioni, Carolina R. S. Elzinga & Martina Schmidt. (2008) Epac: effectors and biological functions. Naunyn-Schmiedeberg's Archives of Pharmacology 377:4-6, pages 345-357.
Crossref
John S. O'NeillElizabeth S. MaywoodJohanna E. CheshamJoseph S. TakahashiMichael H. Hastings. (2008) cAMP-Dependent Signaling as a Core Component of the Mammalian Circadian Pacemaker. Science 320:5878, pages 949-953.
Crossref
Andrea Williams, Sovan Sarkar, Paul Cuddon, Evangelia K Ttofi, Shinji Saiki, Farah H Siddiqi, Luca Jahreiss, Angeleen Fleming, Dean Pask, Paul Goldsmith, Cahir J O'Kane, Rodrigo Andres Floto & David C Rubinsztein. (2008) Novel targets for Huntington's disease in an mTOR-independent autophagy pathway. Nature Chemical Biology 4:5, pages 295-305.
Crossref
Mélanie MétrichAlexandre LucasMonique GastineauJane-Lise SamuelChristophe HeymesEric MorelFrank Lezoualc’h. (2008) Epac Mediates β-Adrenergic Receptor–Induced Cardiomyocyte Hypertrophy. Circulation Research 102:8, pages 959-965.
Crossref
William A. Sands & Timothy M. Palmer. (2008) Regulating gene transcription in response to cyclic AMP elevation. Cellular Signalling 20:3, pages 460-466.
Crossref
George G. Holz, Oleg G. Chepurny & Frank Schwede. (2008) Epac-selective cAMP analogs: New tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors. Cellular Signalling 20:1, pages 10-20.
Crossref
Jennifer L. Rudolph, Geng-Xian Shi, Eda Erdogan, Alan P. Fields & Douglas A. Andres. (2007) Rit mutants confirm role of MEK/ERK signaling in neuronal differentiation and reveal novel Par6 interaction. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1773:12, pages 1793-1800.
Crossref
T. K. Monaghan, C. J. MacKenzie, R. Plevin & E. M. Lutz. (2007) PACAP-38 induces neuronal differentiation of human SH-SY5Y neuroblastoma cells via cAMP-mediated activation of ERK and p38 MAP kinases. Journal of Neurochemistry 0:0, pages 071108171001001-???.
Crossref
Dong Chen, Scott Reierstad, Zhihong Lin, Meiling Lu, Chris Brooks, Newton Li, Joy Innes & Serdar E. Bulun. (2007) Prostaglandin E2 Induces Breast Cancer–Related Aromatase Promoters via Activation of p38 and c-Jun NH2-Terminal Kinase in Adipose Fibroblasts. Cancer Research 67:18, pages 8914-8922.
Crossref
Martina Brock, Ann-Christin Nickel, Beata Madziar, Jan Krzysztof Blusztajn & Brygida Berse. (2007) Differential regulation of the high affinity choline transporter and the cholinergic locus by cAMP signaling pathways. Brain Research 1145, pages 1-10.
Crossref
Matthew J. GerdinLee E. Eiden. (2007) Regulation of PC12 Cell Differentiation by cAMP Signaling to ERK Independent of PKA: Do All the Connections Add Up?. Science's STKE 2007:382.
Crossref
Jeanne Ster, Frédéric De Bock, Nathalie C. Guérineau, Andrea Janossy, Stéphanie Barrère-Lemaire, Johannes L. Bos, Joël Bockaert & Laurent Fagni. (2007) Exchange protein activated by cAMP (Epac) mediates cAMP activation of p38 MAPK and modulation of Ca 2+ -dependent K + channels in cerebellar neurons . Proceedings of the National Academy of Sciences 104:7, pages 2519-2524.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.