Citations (51)
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Clarisse van der Feltz & Aaron A. Hoskins. (2019) Structural and functional modularity of the U2 snRNP in pre-mRNA splicing. Critical Reviews in Biochemistry and Molecular Biology 54:5, pages 443-465.
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Nan-Ying Wu, Che-Sheng Chung & Soo-Chen Cheng. (2017) Role of Cwc24 in the First Catalytic Step of Splicing and Fidelity of 5′ Splice Site Selection. Molecular and Cellular Biology 37:6.
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Ting-Wei Chiang & Soo-Chen Cheng. (2013) A Weak Spliceosome-Binding Domain of Yju2 Functions in the First Step and Bypasses Prp16 in the Second Step of Splicing. Molecular and Cellular Biology 33:9, pages 1746-1755.
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Hsin-Chou Chen, Chi-Kang Tseng, Rong-Tzong Tsai, Che-Sheng Chung & Soo-Chen Cheng. (2013) Link of NTR-Mediated Spliceosome Disassembly with DEAH-Box ATPases Prp2, Prp16, and Prp22. Molecular and Cellular Biology 33:3, pages 514-525.
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Hsueh-Lien Liu & Soo-Chen Cheng. (2012) The Interaction of Prp2 with a Defined Region of the Intron Is Required for the First Splicing Reaction. Molecular and Cellular Biology 32:24, pages 5056-5066.
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Tzu-Chi Yeh, Hseuh-Lien Liu, Che-Sheng Chung, Nan-Ying Wu, Yen-Chi Liu & Soo-Chen Cheng. (2011) Splicing Factor Cwc22 Is Required for the Function of Prp2 and for the Spliceosome To Escape from a Futile Pathway. Molecular and Cellular Biology 31:1, pages 43-53.
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Ying-Fang Chiu, Yen-Chi Liu, Ting-Wei Chiang, Tzu-Chi Yeh, Chi-Kang Tseng, Nan-Ying Wu & Soo-Chen Cheng. (2009) Cwc25 Is a Novel Splicing Factor Required after Prp2 and Yju2 To Facilitate the First Catalytic Reaction. Molecular and Cellular Biology 29:21, pages 5671-5678.
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Rong-Tzong Tsai, Chi-Kang Tseng, Pei-Jung Lee, Hsin-Chou Chen, Ru-Huei Fu, Kae-jiun Chang, Fu-Lung Yeh & Soo-Chen Cheng. (2007) Dynamic Interactions of Ntr1-Ntr2 with Prp43 and with U5 Govern the Recruitment of Prp43 To Mediate Spliceosome Disassembly. Molecular and Cellular Biology 27:23, pages 8027-8037.
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Articles from other publishers (43)
Chi-Kang Tseng & Soo-Chen Cheng. 2023. RNA-Protein Complexes and Interactions. RNA-Protein Complexes and Interactions
193
211
.
Helena Covelo-Molares, Ales Obrdlik, Ivana Poštulková, Michaela Dohnálková, Pavlína Gregorová, Ranjani Ganji, David Potěšil, Lisa Gawriyski, Markku Varjosalo & Štěpánka Vaňáčová. (2021) The comprehensive interactomes of human adenosine RNA methyltransferases and demethylases reveal distinct functional and regulatory features. Nucleic Acids Research 49:19, pages 10895-10910.
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Zuzer Dhoondia, Hesham Elewa, Marva Malik, Zahidur Arif, Roger Pique-Regi & Athar Ansari. (2021) A termination-independent role of Rat1 in cotranscriptional splicing. Nucleic Acids Research 49:10, pages 5520-5536.
Crossref
Crossref
Max E. Wilkinson, Sebastian M. Fica, Wojciech P. Galej & Kiyoshi Nagai. (2021) Structural basis for conformational equilibrium of the catalytic spliceosome. Molecular Cell 81:7, pages 1439-1452.e9.
Crossref
Crossref
Francesca De Bortoli, Sara Espinosa & Rui Zhao. (2021) DEAH-Box RNA Helicases in Pre-mRNA Splicing. Trends in Biochemical Sciences 46:3, pages 225-238.
Crossref
Crossref
Max E. WilkinsonClément CharentonKiyoshi Nagai. (2020) RNA Splicing by the Spliceosome. Annual Review of Biochemistry 89:1, pages 359-388.
Crossref
Crossref
Ruixue WanRui Bai, Xiechao ZhanYigong Shi. (2020) How Is Precursor Messenger RNA Spliced by the Spliceosome?. Annual Review of Biochemistry 89:1, pages 333-358.
Crossref
Crossref
Ruixue Wan, Rui Bai & Yigong Shi. (2019) Molecular choreography of pre-mRNA splicing by the spliceosome. Current Opinion in Structural Biology 59, pages 124-133.
Crossref
Crossref
Berthold Kastner, Cindy L. Will, Holger Stark & Reinhard Lührmann. (2019) Structural Insights into Nuclear pre-mRNA Splicing in Higher Eukaryotes. Cold Spring Harbor Perspectives in Biology 11:11, pages a032417.
Crossref
Crossref
Ruixue Wan, Rui Bai, Chuangye Yan, Jianlin Lei & Yigong Shi. (2019) Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell 177:2, pages 339-351.e13.
Crossref
Crossref
Che-Sheng Chung, Chi-Kang Tseng, Yung-Hua Lai, Hui-Fang Wang, Andrew J Newman & Soo-Chen Cheng. (2019) Dynamic protein–RNA interactions in mediating splicing catalysis. Nucleic Acids Research 47:2, pages 899-910.
Crossref
Crossref
Yu-Lun Su, Hsin-Chou Chen, Rong-Tzong Tsai, Pei-Chun Lin & Soo-Chen Cheng. (2018) Cwc23 is a component of the NTR complex and functions to stabilize Ntr1 and facilitate disassembly of spliceosome intermediates. Nucleic Acids Research 46:7, pages 3764-3773.
Crossref
Crossref
Xiechao Zhan, Chuangye Yan, Xiaofeng Zhang, Jianlin LeiYigong Shi. (2018) Structure of a human catalytic step I spliceosome. Science 359:6375, pages 537-545.
Crossref
Crossref
Penghui Bao, Cindy L. Will, Henning Urlaub, Kum-Loong Boon & Reinhard Lührmann. (2017)
The RES complex is required for efficient transformation of the precatalytic B spliceosome into an activated B
act
complex
. Genes & Development 31:23-24, pages 2416-2429.
Crossref
Crossref
Sjors HW Scheres & Kiyoshi Nagai. (2017) CryoEM structures of spliceosomal complexes reveal the molecular mechanism of pre-mRNA splicing. Current Opinion in Structural Biology 46, pages 130-139.
Crossref
Crossref
Tatsuo Kanno, Wen-Dar Lin, Jason L. Fu, Antonius J.M. Matzke & Marjori Matzke. (2017)
A genetic screen implicates a CWC16/Yju2/CCDC130 protein and SMU1 in alternative splicing in
Arabidopsis thaliana
. RNA 23:7, pages 1068-1079.
Crossref
Crossref
John Abelson. (2017) A close-up look at the spliceosome, at last. Proceedings of the National Academy of Sciences 114:17, pages 4288-4293.
Crossref
Crossref
Chi-Kang Tseng, Che-Sheng Chung, Hsin-Chou Chen & Soo-Chen Cheng. (2017) A central role of Cwc25 in spliceosome dynamics during the catalytic phase of pre-mRNA splicing. RNA 23:4, pages 546-556.
Crossref
Crossref
Ruixue WanChuangye YanRui BaiGaoxingyu HuangYigong Shi. (2016) Structure of a yeast catalytic step I spliceosome at 3.4 Å resolution. Science 353:6302, pages 895-904.
Crossref
Crossref
Noriko Sasaki-Haraguchi, Takeshi Ikuyama, Shogo Yoshii, Tomoko Takeuchi-Andoh, David Frendewey & Tokio Tani. (2015) Cwf16p Associating with the Nineteen Complex Ensures Ordered Exon Joining in Constitutive Pre-mRNA Splicing in Fission Yeast. PLOS ONE 10:8, pages e0136336.
Crossref
Crossref
Rui G. Martinho, Leonardo G. Guilgur & Pedro Prudêncio. (2015) How gene expression in fast-proliferating cells keeps pace. BioEssays 37:5, pages 514-524.
Crossref
Crossref
Martha R. Stark, Elizabeth A. Dunn, William S. C. Dunn, Cameron J. Grisdale, Anthony R. Daniele, Matthew R. G. Halstead, Naomi M. Fast & Stephen D. Rader. (2015)
Dramatically reduced spliceosome in
Cyanidioschyzon merolae
. Proceedings of the National Academy of Sciences 112:11.
Crossref
Crossref
Hsin-Chou Chen, Kae-Jiun Chang, Yu-Lun Su, Yu-Hsin Huang & Soo-Chen Cheng. (2014) Structural requirement of Ntc77 for spliceosome activation and first catalytic step. Nucleic Acids Research 42:19, pages 12261-12271.
Crossref
Crossref
Hani Kotzer-Nevo, Flavia de Lima Alves, Juri Rappsilber, Joseph Sperling & Ruth Sperling. (2014) Supraspliceosomes at Defined Functional States Portray the Pre-Assembled Nature of the Pre-mRNA Processing Machine in the Cell Nucleus. International Journal of Molecular Sciences 15:7, pages 11637-11664.
Crossref
Crossref
Alissa M. Wlodaver & Jonathan P. Staley. (2014) The DExD/H-box ATPase Prp2p destabilizes and proofreads the catalytic RNA core of the spliceosome. RNA 20:3, pages 282-294.
Crossref
Crossref
Sittinan Chanarat & Katja Sträßer. (2013) Splicing and beyond: The many faces of the Prp19 complex. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1833:10, pages 2126-2134.
Crossref
Crossref
Thomas Ohrt, Peter Odenwälder, Julia Dannenberg, Mira Prior, Zbigniew Warkocki, Jana Schmitzová, Ramazan Karaduman, Ingo Gregor, Jörg Enderlein, Patrizia Fabrizio & Reinhard Lührmann. (2013) Molecular dissection of step 2 catalysis of yeast pre-mRNA splicing investigated in a purified system. RNA 19:7, pages 902-915.
Crossref
Crossref
Chi-Kang Tseng & Soo-Chen Cheng. (2013) The spliceosome catalyzes debranching in competition with reverse of the first chemical reaction. RNA 19:7, pages 971-981.
Crossref
Crossref
Daniel J. Crawford, Aaron A. Hoskins, Larry J. Friedman, Jeff Gelles & Melissa J. Moore. (2013) Single-molecule colocalization FRET evidence that spliceosome activation precedes stable approach of 5′ splice site and branch site. Proceedings of the National Academy of Sciences 110:17, pages 6783-6788.
Crossref
Crossref
Maria de Lourdes Coelho Ribeiro, Julio Espinosa, Sameen Islam, Osvaldo Martinez, Jayesh Jamnadas Thanki, Stephanie Mazariegos, Tam Nguyen, Maya Larina, Bin Xue & Vladimir N. Uversky. (2013)
Malleable ribonucleoprotein machine: protein intrinsic disorder in the
Saccharomyces cerevisiae
spliceosome
. PeerJ 1, pages e2.
Crossref
Crossref
Prashant Kumar Singh, Shivani Kanodia, Chethan Jambanna Dandin, Usha Vijayraghavan & Pawan Malhotra. (2012) Plasmodium falciparum Prp16 homologue and its role in splicing. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1819:11-12, pages 1186-1199.
Crossref
Crossref
Hsin-Chou Chen & Soo-Chen Cheng. (2012) Functional roles of protein splicing factors. Bioscience Reports 32:4, pages 345-359.
Crossref
Crossref
Thomas Ohrt, Mira Prior, Julia Dannenberg, Peter Odenwälder, Olexandr Dybkov, Nicolas Rasche, Jana Schmitzová, Ingo Gregor, Patrizia Fabrizio, Jörg Enderlein & Reinhard Lührmann. (2012) Prp2-mediated protein rearrangements at the catalytic core of the spliceosome as revealed by dcFCCS. RNA 18:6, pages 1244-1256.
Crossref
Crossref
Jana Schmitzová, Nicolas Rasche, Olexander Dybkov, Katharina Kramer, Patrizia Fabrizio, Henning Urlaub, Reinhard Lührmann & Vladimir Pena. (2012) Crystal structure of Cwc2 reveals a novel architecture of a multipartite RNA-binding protein. The EMBO Journal 31:9, pages 2222-2234.
Crossref
Crossref
David S. Horowitz. (2012) The mechanism of the second step of pre-mRNA splicing. Wiley Interdisciplinary Reviews: RNA 3:3, pages 331-350.
Crossref
Crossref
David S. Horowitz. (2011) The splice is right: Guarantors of fidelity in pre-mRNA splicing: FIGURE 1.. RNA 17:4, pages 551-554.
Crossref
Crossref
Chi-Kang Tseng, Hsueh-Lien Liu & Soo-Chen Cheng. (2011) DEAH-box ATPase Prp16 has dual roles in remodeling of the spliceosome in catalytic steps. RNA 17:1, pages 145-154.
Crossref
Crossref
Saba Valadkhan & Yasaman Jaladat. (2010) The spliceosomal proteome: At the heart of the largest cellular ribonucleoprotein machine. PROTEOMICS 10:22, pages 4128-4141.
Crossref
Crossref
Rebecca HoggJoanne C. McGrailRaymond T. O'Keefe. (2010) The function of the NineTeen Complex (NTC) in regulating spliceosome conformations and fidelity during pre-mRNA splicing. Biochemical Society Transactions 38:4, pages 1110-1115.
Crossref
Crossref
Rea M. Lardelli, James X. Thompson, John R. YatesIIIIII & Scott W. Stevens. (2010) Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing. RNA 16:3, pages 516-528.
Crossref
Crossref
Zbigniew Warkocki, Peter Odenwälder, Jana Schmitzová, Florian Platzmann, Holger Stark, Henning Urlaub, Ralf Ficner, Patrizia Fabrizio & Reinhard Lührmann. (2009) Reconstitution of both steps of Saccharomyces cerevisiae splicing with purified spliceosomal components. Nature Structural & Molecular Biology 16:12, pages 1237-1243.
Crossref
Crossref
Patrizia Fabrizio, Julia Dannenberg, Prakash Dube, Berthold Kastner, Holger Stark, Henning Urlaub & Reinhard Lührmann. (2009) The Evolutionarily Conserved Core Design of the Catalytic Activation Step of the Yeast Spliceosome. Molecular Cell 36:4, pages 593-608.
Crossref
Crossref
Kae-Jiun Chang, Hsin-Chou Chen & Soo-Chen Cheng. (2009) Ntc90 is required for recruiting first step factor Yju2 but not for spliceosome activation. RNA 15:9, pages 1729-1739.
Crossref
Crossref