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Article

Activation of Receptor Activator of NF-κB Ligand Gene Expression by 1,25-Dihydroxyvitamin D3 Is Mediated through Multiple Long-Range Enhancers

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Pages 6469-6486 | Received 27 Feb 2006, Accepted 12 Jun 2006, Published online: 27 Mar 2023

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Jesús Delgado-Calle, Carolina Sañudo, Agustín F. Fernández, Raúl García-Renedo, Mario F. Fraga & José A. Riancho. (2012) Role of DNA methylation in the regulation of the RANKL-OPG system in human bone. Epigenetics 7:1, pages 83-91.
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Qiang Fu, Stavros C. Manolagas & Charles A. O'Brien. (2006) Parathyroid Hormone Controls Receptor Activator of NF-κB Ligand Gene Expression via a Distant Transcriptional Enhancer. Molecular and Cellular Biology 26:17, pages 6453-6468.
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Sylvia Christakos & J. Wesley Pike. 2020. Principles of Bone Biology. Principles of Bone Biology 739 756 .
Daniel D. Bikle. 2020. Principles of Bone Biology. Principles of Bone Biology 713 737 .
Philip B. MayJrJr & Stephen J. Winters. (2019) Weight-Bearing Physical Activity Influences the Effect of Vitamin D on Bone Turnover Markers in Patients with Intellectual Disability. Southern Medical Journal 112:8, pages 428-432.
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Lishan Li, Shitao Rao, Yanzhen Cheng, Xiaoyun Zhuo, Caihong Deng, Ningning Xu, Hua Zhang & Li Yang. (2019) Microbial osteoporosis: The interplay between the gut microbiota and bones via host metabolism and immunity. MicrobiologyOpen 8:8.
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Sungsin Jo, Yun Young Lee, Jinil Han, Young Lim Lee, Subin Yoon, Jaehyun Lee, Younseo Oh, Joong-Soo Han, Il-Hoon Sung, Ye-Soo Park & Tae-Hwan Kim. (2019) CCAAT/enhancer-binding protein beta (C/EBPβ) is an important mediator of 1,25 dihydroxyvitamin D3 (1,25D3)-induced receptor activator of nuclear factor kappa-B ligand (RANKL) expression in osteoblasts. BMB Reports 52:6, pages 391-396.
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Marc N. Wein & Henry M. Kronenberg. (2018) Regulation of Bone Remodeling by Parathyroid Hormone. Cold Spring Harbor Perspectives in Medicine 8:8, pages a031237.
Crossref
Dong-Li Zhu, Xiao-Feng Chen, Wei-Xin Hu, Shan-Shan Dong, Bing-Jie Lu, Yu Rong, Yi-Xiao Chen, Hao Chen, Hlaing Nwe Thynn, Nai-Ning Wang, Yan Guo & Tie-Lin Yang. (2018) Multiple Functional Variants at 13q14 Risk Locus for Osteoporosis Regulate RANKL Expression Through Long-Range Super-Enhancer . Journal of Bone and Mineral Research 33:7, pages 1335-1346.
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Ihor Shymanskyi, Olha Lisakovska, Anna Mazanova, Dmytro Labudzynskyi & Mykola Veliky. (2018) Vitamin D3 Modulates Impaired Crosstalk Between RANK and Glucocorticoid Receptor Signaling in Bone Marrow Cells After Chronic Prednisolone Administration. Frontiers in Endocrinology 9.
Crossref
Kimie Nakagawa, Yumi Okubo & Ritsuko Masuyama. (2018) Vitamin Status and Mineralized Tissue Development. Current Oral Health Reports 5:2, pages 89-95.
Crossref
D. Goltzman. (2018) Functions of vitamin D in bone. Histochemistry and Cell Biology 149:4, pages 305-312.
Crossref
Dongqing Yang, Paul H. Anderson, Asiri R. Wijenayaka, Kate R. Barratt, Rahma Triliana, Catherine J.M. Stapledon, Hong Zhou, David M. Findlay, Howard A. Morris & Gerald J. Atkins. (2018) Both ligand and VDR expression levels critically determine the effect of 1α,25-dihydroxyvitamin-D3 on osteoblast differentiation. The Journal of Steroid Biochemistry and Molecular Biology 177, pages 83-90.
Crossref
Daniel J. Owens, Richard Allison & Graeme L. Close. (2018) Vitamin D and the Athlete: Current Perspectives and New Challenges. Sports Medicine 48:S1, pages 3-16.
Crossref
David Goltzman, Geoffrey N. Hendy, Andrew C. Karaplis, Richard Kremer & Denshun Miao. 2018. Vitamin D. Vitamin D 613 631 .
Brian L. Foster & Philippe P. Hujoel. 2018. Vitamin D. Vitamin D 497 519 .
Geert Carmeliet. 2018. Vitamin D. Vitamin D 419 433 .
Jeroen van de Peppel, Renny T. Franceschi, Yan Li & Bram C.J. van der Eerden. 2018. Vitamin D. Vitamin D 295 308 .
J. Wesley Pike, Mark B. Meyer, Seong M. Lee, Melda Onal & Nancy A. Benkusky. 2018. Vitamin D. Vitamin D 141 174 .
Hector F. DeLuca. 2018. Vitamin D. Vitamin D 3 12 .
Hiroshi Saitoh. 2018. Vitamin D. Vitamin D 679 693 .
Makoto Makishima & Sachiko Yamada. 2018. Vitamin D. Vitamin D 629 646 .
Adriana S. Dusso & Jorge B. Cannata-Andia. 2018. Vitamin D. Vitamin D 445 469 .
J. Wesley Pike, Seong M. Lee & Mark B. Meyer. 2018. Physiology of the Gastrointestinal Tract. Physiology of the Gastrointestinal Tract 1153 1180 .
Daniel D. Bikle. 2018. Extraskeletal Effects of Vitamin D. Extraskeletal Effects of Vitamin D 1 40 .
Marc N Wein. (2018) Parathyroid Hormone Signaling in Osteocytes. JBMR Plus 2:1, pages 22-30.
Crossref
J. Wesley Pike & Sylvia Christakos. (2017) Biology and Mechanisms of Action of the Vitamin D Hormone. Endocrinology and Metabolism Clinics of North America 46:4, pages 815-843.
Crossref
Sohel Shamsuzzaman, Melda Onal, Hillary C. St John & J. Wesley Pike. (2017) Deletion of a Distal RANKL Gene Enhancer Delays Progression of Atherosclerotic Plaque Calcification in Hypercholesterolemic Mice . Journal of Cellular Biochemistry 118:12, pages 4240-4253.
Crossref
Jesus Delgado-Calle, Xiaolin Tu, Rafael Pacheco-Costa, Kevin McAndrews, Rachel Edwards, Gretel G Pellegrini, Kali Kuhlenschmidt, Naomie Olivos, Alexander Robling, Munro Peacock, Lilian I Plotkin & Teresita Bellido. (2017) Control of Bone Anabolism in Response to Mechanical Loading and PTH by Distinct Mechanisms Downstream of the PTH Receptor. Journal of Bone and Mineral Research 32:3, pages 522-535.
Crossref
Zhan Xu, Matthew B. Greenblatt, Guang Yan, Heng Feng, Jun Sun, Sutada Lotinun, Nicholas Brady, Roland Baron, Laurie H. Glimcher & Weiguo Zou. (2017) SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblasts. Nature Communications 8:1.
Crossref
Kevin N Keane, Vinicius F Cruzat, Emily K Calton, Prue H Hart, Mario J Soares, Philip Newsholme & John L Yovich. (2017) Molecular actions of vitamin D in reproductive cell biology. Reproduction 153:1, pages R29-R42.
Crossref
Olena V. Andrukhova & Reinhold G. Erben. 2017. Bone Toxicology. Bone Toxicology 335 362 .
Marc N. Wein, Yanke Liang, Olga Goransson, Thomas B. Sundberg, Jinhua Wang, Elizabeth A. Williams, Maureen J. O’Meara, Nicolas Govea, Belinda Beqo, Shigeki Nishimori, Kenichi Nagano, Daniel J. Brooks, Janaina S. Martins, Braden Corbin, Anthony Anselmo, Ruslan Sadreyev, Joy Y. Wu, Kei Sakamoto, Marc Foretz, Ramnik J. Xavier, Roland Baron, Mary L. Bouxsein, Thomas J. Gardella, Paola Divieti-Pajevic, Nathanael S. Gray & Henry M. Kronenberg. (2016) SIKs control osteocyte responses to parathyroid hormone. Nature Communications 7:1.
Crossref
Katherine Meckel, Yan Chun Li, John Lim, Masha Kocherginsky, Chris Weber, Anas Almoghrabi, Xindi Chen, Austin Kaboff, Farhana Sadiq, Stephen B Hanauer, Russell D Cohen, John Kwon, David T Rubin, Ira Hanan, Atsushi Sakuraba, Eugene Yen, Marc Bissonnette & Joel Pekow. (2016) Serum 25-hydroxyvitamin D concentration is inversely associated with mucosal inflammation in patients with ulcerative colitis,. The American Journal of Clinical Nutrition 104:1, pages 113-120.
Crossref
Binghan Li, Dan Lu, Yuqing Chen, Minghui Zhao & Li Zuo. (2016) Unfractionated Heparin Promotes Osteoclast Formation in Vitro by Inhibiting Osteoprotegerin Activity. International Journal of Molecular Sciences 17:4, pages 613.
Crossref
M. Onal, H. C. St. John, A. L. Danielson, J. W. Markert, E. M. Riley & J. W. Pike. (2016) Unique Distal Enhancers Linked to the Mouse Tnfsf11 Gene Direct Tissue-Specific and Inflammation-Induced Expression of RANKL. Endocrinology 157:2, pages 482-496.
Crossref
Robert L. Jilka & Charles A. O’Brien. (2016) The Role of Osteocytes in Age-Related Bone Loss. Current Osteoporosis Reports 14:1, pages 16-25.
Crossref
Melda Onal, Hillary C St. John, Allison L Danielson & J Wesley Pike. (2016) Deletion of the Distal Tnfsf11 RL-D2 Enhancer That Contributes to PTH-Mediated RANKL Expression in Osteoblast Lineage Cells Results in a High Bone Mass Phenotype in Mice . Journal of Bone and Mineral Research 31:2, pages 416-429.
Crossref
Ritobrata Goswami & Mark H Kaplan. (2016) Essential vitamins for an effective T cell response. World Journal of Immunology 6:1, pages 39.
Crossref
Tong Xu, Lu Wang, You Tao, Yan Ji, Feng Deng & Xiao-Hong Wu. (2016) The Function of Naringin in Inducing Secretion of Osteoprotegerin and Inhibiting Formation of Osteoclasts. Evidence-Based Complementary and Alternative Medicine 2016, pages 1-7.
Crossref
Sylvia Christakos, Puneet Dhawan, Annemieke Verstuyf, Lieve Verlinden & Geert Carmeliet. (2016) Vitamin D: Metabolism, Molecular Mechanism of Action, and Pleiotropic Effects. Physiological Reviews 96:1, pages 365-408.
Crossref
Mark R. Haussler, G. Kerr Whitfield, Carol A. Haussler, Marya S. Sabir, Zainab Khan, Ruby Sandoval & Peter W. Jurutka. 2016. Vitamin D Hormone. Vitamin D Hormone 165 230 .
J. Wesley Pike, Mark B. Meyer, Nancy A. Benkusky, Seong Min Lee, Hillary St. John, Alex Carlson, Melda Onal & Sohel Shamsuzzaman. 2016. Vitamin D Hormone. Vitamin D Hormone 21 44 .
Kelly A. Teske, Olivia Yu & Leggy A. Arnold. 2016. Vitamin D Hormone. Vitamin D Hormone 45 82 .
Mark R. Haussler, Rimpi K. Saini, Marya S. Sabir, Christopher M. Dussik, Zainab Khan, G. Kerr Whitfield, Kristin P. Griffin, Ichiro Kaneko & Peter W. Jurutka. 2016. Molecular Basis of Nutrition and Aging. Molecular Basis of Nutrition and Aging 449 471 .
Adriana S. Dusso. 2016. Vitamin D in Chronic Kidney Disease. Vitamin D in Chronic Kidney Disease 51 74 .
Seong Min Lee, Mark B. Meyer, Nancy A. Benkusky, Charles A. O'Brien & J.Wesley Pike. (2015) Mechanisms of Enhancer-mediated Hormonal Control of Vitamin D Receptor Gene Expression in Target Cells. Journal of Biological Chemistry 290:51, pages 30573-30586.
Crossref
J. Wesley Pike, Mark B. Meyer, Hillary C. St. John & Nancy A. Benkusky. (2015) Epigenetic histone modifications and master regulators as determinants of context dependent nuclear receptor activity in bone cells. Bone 81, pages 757-764.
Crossref
Jinhu Xiong, Marilina Piemontese, Melda Onal, Josh Campbell, Joseph J. Goellner, Vladimir Dusevich, Lynda Bonewald, Stavros C. Manolagas & Charles A. O’Brien. (2015) Osteocytes, not Osteoblasts or Lining Cells, are the Main Source of the RANKL Required for Osteoclast Formation in Remodeling Bone. PLOS ONE 10:9, pages e0138189.
Crossref
Asiri R. Wijenayaka, Dongqing Yang, Matthew Prideaux, Nobuaki Ito, Masakazu Kogawa, Paul H. Anderson, Howard A. Morris, Lucian B. Solomon, Gabriela G. Loots, David M. Findlay & Gerald J. Atkins. (2015) 1α,25-dihydroxyvitamin D3 stimulates human SOST gene expression and sclerostin secretion. Molecular and Cellular Endocrinology 413, pages 157-167.
Crossref
Tatsuo Suda, Ritsuko Masuyama, Roger Bouillon & Geert Carmeliet. (2015) Physiological functions of vitamin D: what we have learned from global and conditional VDR knockout mouse studies. Current Opinion in Pharmacology 22, pages 87-99.
Crossref
Melda Onal, Kathleen A Bishop, Hillary C St. John, Allison L Danielson, Erin M Riley, Marilina Piemontese, Jinhu Xiong, Joseph J Goellner, Charles A O'Brien & J Wesley Pike. (2015) A DNA Segment Spanning the Mouse Tnfsf11 Transcription Unit and Its Upstream Regulatory Domain Rescues the Pleiotropic Biologic Phenotype of the RANKL Null Mouse . Journal of Bone and Mineral Research 30:5, pages 855-868.
Crossref
Mark B. Meyer, Nancy A. Benkusky & J. Wesley Pike. (2015) Selective Distal Enhancer Control of the Mmp13 Gene Identified through Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) Genomic Deletions. Journal of Biological Chemistry 290:17, pages 11093-11107.
Crossref
Rui Zhou, Rene F. Chun, Thomas S. Lisse, Alejandro J. Garcia, Jianzhong Xu, John S. Adams & Martin Hewison. (2015) Vitamin D and alternative splicing of RNA. The Journal of Steroid Biochemistry and Molecular Biology 148, pages 310-317.
Crossref
D Goltzman. (2015) Inferences from genetically modified mouse models on the skeletal actions of vitamin D. The Journal of Steroid Biochemistry and Molecular Biology 148, pages 219-224.
Crossref
Hillary C. St. John, Mark B. Meyer, Nancy A. Benkusky, Alex H. Carlson, Mathew Prideaux, Lynda F. Bonewald & J. Wesley Pike. (2015) The parathyroid hormone-regulated transcriptome in osteocytes: Parallel actions with 1,25-dihydroxyvitamin D3 to oppose gene expression changes during differentiation and to promote mature cell function. Bone 72, pages 81-91.
Crossref
Kumaran Sundaram, Yuvaraj Sambandam, Sundaravadivel Balasubramanian, Balakrishnan Pillai, Christina Voelkel-Johnson, William L. Ries & Sakamuri V. Reddy. (2015) STAT-6 mediates TRAIL induced RANK ligand expression in stromal/preosteoblast cells. Bone 71, pages 137-144.
Crossref
D. Goltzman, G.N. Hendy & J.H. White. (2015) Vitamin D and its receptor during late development. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1849:2, pages 171-180.
Crossref
Kathleen A. Bishop, Xiaohua Wang, Heidi M. Coy, Mark B. Meyer, Jenny E. Gumperz & J. Wesley Pike. (2015) Transcriptional Regulation of the Human TNFSF11 Gene in T Cells via a Cell Type-Selective Set of Distal Enhancers . Journal of Cellular Biochemistry 116:2, pages 320-330.
Crossref
. (2015) 局所的なビタミンDの機能と骨・ミネラル恒常性. Japanese Journal of Physical Fitness and Sports Medicine 64:1, pages 75-75.
Crossref
David Goltzman & Andrew C. Karaplis. 2015. Hypoparathyroidism. Hypoparathyroidism 69 79 .
Sandra L. Grimm, Robert D. Ward, Alison E. Obr, Heather L. Franco, Rodrigo Fernandez-Valdivia, Jung-Sun Kim, Justin M. Roberts, Jae-Wook Jeong, Francesco J. DeMayo, John P. Lydon, Dean P. Edwards & Nancy L. Weigel. (2014) A Role for Site-Specific Phosphorylation of Mouse Progesterone Receptor at Serine 191 in Vivo. Molecular Endocrinology 28:12, pages 2025-2037.
Crossref
J. Wesley Pike & Mark B. Meyer. (2014) Fundamentals of vitamin D hormone-regulated gene expression. The Journal of Steroid Biochemistry and Molecular Biology 144, pages 5-11.
Crossref
Mark B. Meyer, Nancy A. Benkusky & J. Wesley Pike. (2014) 1,25-Dihydroxyvitamin D3 induced histone profiles guide discovery of VDR action sites. The Journal of Steroid Biochemistry and Molecular Biology 144, pages 19-21.
Crossref
Jinhu Xiong, Marilina Piemontese, Jeff D. Thostenson, Robert S. Weinstein, Stavros C. Manolagas & Charles A. O'Brien. (2014) Osteocyte-derived RANKL is a critical mediator of the increased bone resorption caused by dietary calcium deficiency. Bone 66, pages 146-154.
Crossref
Alexandre S. Stephens & Nigel A. Morrison. (2014) Novel Target Genes of RUNX2 Transcription Factor and 1,25-Dihydroxyvitamin D3. Journal of Cellular Biochemistry 115:9, pages 1594-1608.
Crossref
Mark B. Meyer, Nancy A. Benkusky, Chang-Hun Lee & J.Wesley Pike. (2014) Genomic Determinants of Gene Regulation by 1,25-Dihydroxyvitamin D3 during Osteoblast-lineage Cell Differentiation. Journal of Biological Chemistry 289:28, pages 19539-19554.
Crossref
Mark B. Meyer, Nancy A. Benkusky & J. Wesley Pike. (2014) The RUNX2 Cistrome in Osteoblasts. Journal of Biological Chemistry 289:23, pages 16016-16031.
Crossref
Beate Lanske, Michael J Densmore & Reinhold G Erben. (2014) Vitamin D endocrine system and osteocytes. BoneKEy Reports 3.
Crossref
Stefano Zanotti, Ivo Kalajzic, Hector Leonardo Aguila & Ernesto Canalis. (2014) Sex and Genetic Factors Determine Osteoblastic Differentiation Potential of Murine Bone Marrow Stromal Cells. PLoS ONE 9:1, pages e86757.
Crossref
J Wesley Pike, Seong Min Lee & Mark B Meyer. (2014) Regulation of gene expression by 1,25-dihydroxyvitamin D3 in bone cells: exploiting new approaches and defining new mechanisms. BoneKEy Reports 3.
Crossref
Ritsuko Masuyama. (2013) Role of local vitamin D signaling and cellular calcium transport system in bone homeostasis. Journal of Bone and Mineral Metabolism 32:1, pages 1-9.
Crossref
Guy Yoskovitz, Natalia Garcia-Giralt, Maria Rodriguez-Sanz, Roser Urreizti, Robert Guerri, Sergi Ariño-Ballester, Daniel Prieto-Alhambra, Leonardo Mellibovsky, Daniel Grinberg, Xavier Nogues, Susana Balcells & Adolfo Diez-Perez. (2013) Analyses of RANK and RANKL in the Post-GWAS Context: Functional Evidence of Vitamin D Stimulation Through a RANKL Distal Region . Journal of Bone and Mineral Research 28:12, pages 2550-2560.
Crossref
Alison E. Obr, Sandra L. Grimm, Kathleen A. Bishop, J. Wesley Pike, John P. Lydon & Dean P. Edwards. (2013) Progesterone Receptor and Stat5 Signaling Cross Talk Through RANKL in Mammary Epithelial Cells. Molecular Endocrinology 27:11, pages 1808-1824.
Crossref
Kumaran Sundaram, Joseph Senn & Sakamuri V. Reddy. (2013) SOCS-1/3 participation in FGF-2 signaling to modulate RANK ligand expression in paget's disease of bone. Journal of Cellular Biochemistry 114:9, pages 2032-2038.
Crossref
Jun-ichi Satoh & Hiroko Tabunoki. (2013) Molecular network of chromatin immunoprecipitation followed by deep sequencing-based vitamin D receptor target genes. Multiple Sclerosis Journal 19:8, pages 1035-1045.
Crossref
N C Walsh, K A Alexander, C A Manning, S K Karmakar, J F Wang, C M Weyand, A R Pettit & E M Gravallese. (2013) Activated human T cells express alternative mRNA transcripts encoding a secreted form of RANKL. Genes & Immunity 14:5, pages 336-345.
Crossref
Liesbet Lieben & Geert Carmeliet. (2013) Vitamin D signaling in osteocytes: Effects on bone and mineral homeostasis. Bone 54:2, pages 237-243.
Crossref
Charles A. O'Brien, Tomoki Nakashima & Hiroshi Takayanagi. (2013) Osteocyte control of osteoclastogenesis. Bone 54:2, pages 258-263.
Crossref
Kumaran Sundaram, D Sudhaker Rao, William L Ries & Sakamuri V Reddy. (2013) CXCL5 stimulation of RANK ligand expression in Paget's disease of bone. Laboratory Investigation 93:4, pages 472-479.
Crossref
Rimpi K. Saini, Ichiro Kaneko, Peter W. Jurutka, Ryan Forster, Antony Hsieh, Jui-Cheng Hsieh, Mark R. Haussler & G. Kerr Whitfield. (2012) 1,25-Dihydroxyvitamin D3 Regulation of Fibroblast Growth Factor-23 Expression in Bone Cells: Evidence for Primary and Secondary Mechanisms Modulated by Leptin and Interleukin-6. Calcified Tissue International 92:4, pages 339-353.
Crossref
Mark R. Haussler, G. Kerr Whitfield, Ichiro Kaneko, Carol A. Haussler, David Hsieh, Jui-Cheng Hsieh & Peter W. Jurutka. (2012) Molecular Mechanisms of Vitamin D Action. Calcified Tissue International 92:2, pages 77-98.
Crossref
Xiaoke Feng, Chengyin Lv, Fang Wang, Ke Gan, Miaojia Zhang & Wenfeng Tan. (2013) Modulatory Effect of 1,25-Dihydroxyvitamin D 3 on IL1 β -Induced RANKL, OPG, TNF α , and IL-6 Expression in Human Rheumatoid Synoviocyte MH7A . Clinical and Developmental Immunology 2013, pages 1-8.
Crossref
Maya Styner, Mark B. Meyer, Kornelia Galior, Natasha Case, Zhihui Xie, Buer Sen, William R. Thompson, John Wesley Pike & Janet Rubin. (2012) Mechanical Strain Downregulates C/EBPβ in MSC and Decreases Endoplasmic Reticulum Stress. PLoS ONE 7:12, pages e51613.
Crossref
Adrian GombartPeter Jurutka, G Whitfield, Ryan Forster, Shane Batie, Jamie Lee & Mark Haussler. 2012. Vitamin D. Vitamin D 3 36 .
Alfred C. GriffinIIIIII, Michael J. Kern & Keith L. Kirkwood. (2012) MKP-1 Is Essential for Canonical Vitamin D-Induced Signaling through Nuclear Import and Regulates RANKL Expression and Function. Molecular Endocrinology 26:10, pages 1682-1693.
Crossref
Zine Kechrid, Malika Hamdi, Mustafa Nazıroğlu & Manuel Flores-Arce. (2012) Vitamin D Supplementation Modulates Blood and Tissue Zinc, Liver Glutathione and Blood Biochemical Parameters in Diabetic Rats on a Zinc-Deficient Diet. Biological Trace Element Research 148:3, pages 371-377.
Crossref
Nicole M. ColletteDamian C. GenetosAris N. EconomidesLiQin XieMohammad ShahnazariWei YaoNancy E. LaneRichard M. Harland & Gabriela G. Loots. (2012) Targeted deletion of Sost distal enhancer increases bone formation and bone mass . Proceedings of the National Academy of Sciences 109:35, pages 14092-14097.
Crossref
J. Wesley Pike & Mark B. Meyer. (2012) Regulation of mouse Cyp24a1 expression via promoter-proximal and downstream-distal enhancers highlights new concepts of 1,25-dihydroxyvitamin D3 action. Archives of Biochemistry and Biophysics 523:1, pages 2-8.
Crossref
Agnieszka Glebocka & Grazia Chiellini. (2012) A-ring analogs of 1,25-dihydroxyvitamin D3. Archives of Biochemistry and Biophysics 523:1, pages 48-57.
Crossref
Marc N. WeinDallas C. JonesJae-Hyuck ShimAntonios O. AliprantisRosalyn SulyantoVanja LazarevicSandra L. PoliachikTed S. GrossLaurie H. Glimcher. (2012) Control of bone resorption in mice by Schnurri-3. Proceedings of the National Academy of Sciences 109:21, pages 8173-8178.
Crossref
Renny T. Franceschi, Chunxi Ge & Christopher G. Wilson. 2012. Mineralized Tissues in Oral and Craniofacial Science. Mineralized Tissues in Oral and Craniofacial Science 43 57 .
J. Wesley Pike, Mark B. Meyer & Kathleen A. Bishop. (2011) Regulation of target gene expression by the vitamin D receptor - an update on mechanisms. Reviews in Endocrine and Metabolic Disorders 13:1, pages 45-55.
Crossref
John H. White. (2011) Vitamin D metabolism and signaling in the immune system. Reviews in Endocrine and Metabolic Disorders 13:1, pages 21-29.
Crossref
Melda Onal, Carlo Galli, Qiang Fu, Jinhu Xiong, Robert S. Weinstein, Stavros C. Manolagas & Charles A. O'Brien. (2012) The RANKL Distal Control Region Is Required for the Increase in RANKL Expression, But Not the Bone Loss, Associated with Hyperparathyroidism or Lactation in Adult Mice. Molecular Endocrinology 26:2, pages 341-348.
Crossref
J. Wesley Pike & Mark B. Meyer. (2012) The Vitamin D Receptor: New Paradigms for the Regulation of Gene Expression by 1,25-Dihydroxyvitamin D3. Rheumatic Disease Clinics of North America 38:1, pages 13-27.
Crossref
Mark B. Meyer, Paul D. Goetsch & J. Wesley Pike. (2012) VDR/RXR and TCF4/β-Catenin Cistromes in Colonic Cells of Colorectal Tumor Origin: Impact on c-FOS and c-MYC Gene Expression. Molecular Endocrinology 26:1, pages 37-51.
Crossref
J.Wesley Pike & Mark B. Meyer. 2012. Physiology of the Gastrointestinal Tract. Physiology of the Gastrointestinal Tract 1681 1709 .
Edward M. Brown & Andrew Arnold. 2012. Surgery of the Thyroid and Parathyroid Glands. Surgery of the Thyroid and Parathyroid Glands 413 432 .
J. Wesley Pike. (2011) Genome-wide principles of gene regulation by the vitamin D receptor and its activating ligand. Molecular and Cellular Endocrinology 347:1-2, pages 3-10.
Crossref
Ryan E. Forster, Peter W. Jurutka, Jui-Cheng Hsieh, Carol A. Haussler, Christine L. Lowmiller, Ichiro Kaneko, Mark R. Haussler & G. Kerr Whitfield. (2011) Vitamin D receptor controls expression of the anti-aging klotho gene in mouse and human renal cells. Biochemical and Biophysical Research Communications 414:3, pages 557-562.
Crossref
Mark R. Haussler, Peter W. Jurutka, Mathew Mizwicki & Anthony W. Norman. (2011) Vitamin D receptor (VDR)-mediated actions of 1α,25(OH)2vitamin D3: Genomic and non-genomic mechanisms. Best Practice & Research Clinical Endocrinology & Metabolism 25:4, pages 543-559.
Crossref
Melissa L. Martowicz, Mark B. Meyer & J. Wesley Pike. (2011) The mouse RANKL gene locus is defined by a broad pattern of histone H4 acetylation and regulated through distinct distal enhancers. Journal of Cellular Biochemistry 112:8, pages 2030-2045.
Crossref
Kathleen A. Bishop, Heidi M. Coy, Robert D. Nerenz, Mark B. Meyer & J. Wesley Pike. (2011) Mouse Rankl Expression Is Regulated in T Cells by c-Fos through a Cluster of Distal Regulatory Enhancers Designated the T Cell Control Region. Journal of Biological Chemistry 286:23, pages 20880-20891.
Crossref
J Wesley Pike. (2011) Genome-scale techniques highlight the epigenome and redefine fundamental principles of gene regulation. Journal of Bone and Mineral Research 26:6, pages 1155-1162.
Crossref
Makoto Makishima & Sachiko Yamada. 2011. Vitamin D. Vitamin D 1509 1524 .
Edward M. Brown. 2011. Vitamin D. Vitamin D 425 456 .
Renny T. Franceschi & Yan Li. 2011. Vitamin D. Vitamin D 321 333 .
Carsten Carlberg. 2011. Vitamin D. Vitamin D 211 226 .
Mark R. Haussler, G. Kerr Whitfield, Carol A. Haussler, Jui-Cheng Hsieh & Peter W. Jurutka. 2011. Vitamin D. Vitamin D 137 170 .
J. Wesley Pike, Mark B. Meyer & Seong Min Lee. 2011. Vitamin D. Vitamin D 97 135 .
Hector F. Deluca. 2011. Vitamin D. Vitamin D 3 12 .
Roberto Nitsch, Valeria Di Dato, Alessandra di Gennaro, Tiziana de Cristofaro, Serena Abbondante, Mario De Felice, Mariastella Zannini & Roberto Di Lauro. (2010) Comparative genomics reveals a functional thyroid-specific element in the far upstream region of the PAX8 gene. BMC Genomics 11:1.
Crossref
John H. White. (2010) Vitamin D as an inducer of cathelicidin antimicrobial peptide expression: Past, present and future. The Journal of Steroid Biochemistry and Molecular Biology 121:1-2, pages 234-238.
Crossref
J. Wesley Pike, Mark B. Meyer, Melissa L. Martowicz, Kathleen A. Bishop, Seong Min Lee, Robert D. Nerenz & Paul D. Goetsch. (2010) Emerging regulatory paradigms for control of gene expression by 1,25-dihydroxyvitamin D3. The Journal of Steroid Biochemistry and Molecular Biology 121:1-2, pages 130-135.
Crossref
J. Wesley Pike & Mark B. Meyer. (2010) The Vitamin D Receptor: New Paradigms for the Regulation of Gene Expression by 1,25-Dihydroxyvitamin D3. Endocrinology and Metabolism Clinics of North America 39:2, pages 255-269.
Crossref
Ling-Qing Yuan, Wei Liu, Rong-Rong Cui, Dan Wang, Ji-Cai Meng, Hui Xie, Xian-Ping Wu, Hou-De Zhou, Ying Lu & Er-Yuan Liao. (2009) Taurine inhibits osteoclastogenesis through the taurine transporter. Amino Acids 39:1, pages 89-99.
Crossref
Mark B. Meyer, Paul D. Goetsch & J. Wesley Pike. (2010) A Downstream Intergenic Cluster of Regulatory Enhancers Contributes to the Induction of CYP24A1 Expression by 1α,25-Dihydroxyvitamin D3. Journal of Biological Chemistry 285:20, pages 15599-15610.
Crossref
Ronald N. Margolis & Sylvia Christakos. (2010) The nuclear receptor superfamily of steroid hormones and vitamin D gene regulation. Annals of the New York Academy of Sciences 1192:1, pages 208-214.
Crossref
Charles A. O'Brien. (2010) Control of RANKL gene expression. Bone 46:4, pages 911-919.
Crossref
Edwin Cheung & W. Lee Kraus. (2010) Genomic Analyses of Hormone Signaling and Gene Regulation. Annual Review of Physiology 72:1, pages 191-218.
Crossref
Lee A. Zella, Mark B. Meyer, Robert D. Nerenz, Seong Min Lee, Melissa L. Martowicz & J. Wesley Pike. (2010) Multifunctional Enhancers Regulate Mouse and Human Vitamin D Receptor Gene Transcription. Molecular Endocrinology 24:1, pages 128-147.
Crossref
S. Ruiz-Gaspà, N. Guañabens, A. Enjuanes, P. Peris, A. Martinez-Ferrer, M. J. Martinez de Osaba, B. Gonzalez, L. Alvarez, A. Monegal, A. Combalia & A. Parés. (2010) Lithocholic acid downregulates vitamin D effects in human osteoblasts. European Journal of Clinical Investigation 40:1, pages 25-34.
Crossref
Carsten Carlberg. 2010. Nuclear Receptors. Nuclear Receptors 419 437 .
Lori A. Plum & Hector F. DeLuca. 2010. Vitamin D. Vitamin D 61 97 .
Carsten Carlberg. 2010. Vitamin D. Vitamin D 255 274 .
Kathleen A. Bishop, Mark B. Meyer & J. Wesley Pike. (2009) A Novel Distal Enhancer Mediates Cytokine Induction of Mouse Rankl Gene Expression. Molecular Endocrinology 23:12, pages 2095-2110.
Crossref
Buer Sen, Maya Styner, Zhihui Xie, Natasha Case, Clinton T. Rubin & Janet Rubin. (2009) Mechanical Loading Regulates NFATc1 and β-Catenin Signaling through a GSK3β Control Node. Journal of Biological Chemistry 284:50, pages 34607-34617.
Crossref
Kumaran Sundaram, Joseph Senn, Sambandam Yuvaraj, D. Sudhaker Rao & Sakamuri V. Reddy. (2009) FGF-2 Stimulation of RANK Ligand Expression in Paget’s Disease of Bone. Molecular Endocrinology 23:9, pages 1445-1454.
Crossref
Xiaoxue Zhang, Diane R. Dowd, Meika C. Moore, Tanya A. Kranenburg, Magda A. Meester-Smoor, Ellen C. Zwarthoff & Paul N. MacDonald. (2009) Meningioma 1 Is Required for Appropriate Osteoblast Proliferation, Motility, Differentiation, and Function. Journal of Biological Chemistry 284:27, pages 18174-18183.
Crossref
Xiaolin Tang & Huanxin Meng. (2009) Osteogenic induction and 1,25-dihydroxyvitamin D3 oppositely regulate the proliferation and expression of RANKL and the vitamin D receptor of human periodontal ligament cells. Archives of Oral Biology 54:7, pages 625-633.
Crossref
J Wesley Pike, Mark B Meyer & Melissa L Martowicz. (2009) New techniques in transcription research extend our understanding of the molecular actions of the vitamin D hormone. IBMS BoneKEy 6:5, pages 169-180.
Crossref
Anthony N. Gerber, Kiriko MasunoMarc I. Diamond. (2009) Discovery of selective glucocorticoid receptor modulators by multiplexed reporter screening. Proceedings of the National Academy of Sciences 106:12, pages 4929-4934.
Crossref
Lori A. Plum & Hector F. DeLuca. (2009) The Functional Metabolism and Molecular Biology of Vitamin D Action. Clinical Reviews in Bone and Mineral Metabolism 7:1, pages 20-41.
Crossref
Daniel Bikle. (2009) Nonclassic Actions of Vitamin D. The Journal of Clinical Endocrinology & Metabolism 94:1, pages 26-34.
Crossref
You Fu Pan, K. D. Senali Abayratna Wansa, Mei Hui Liu, Bing Zhao, Shu Zhen Hong, Peck Yean Tan, Kar Sian Lim, Guillaume Bourque, Edison T. Liu & Edwin Cheung. (2008) Regulation of Estrogen Receptor-mediated Long Range Transcription via Evolutionarily Conserved Distal Response Elements. Journal of Biological Chemistry 283:47, pages 32977-32988.
Crossref
Alanna Roff & Robin Taylor Wilson. (2008) A novel SNP in a vitamin D response element of the CYP24A1 promoter reduces protein binding, transactivation, and gene expression. The Journal of Steroid Biochemistry and Molecular Biology 112:1-3, pages 47-54.
Crossref
Takuo Kubota, Toshimi Michigami, Naoko Sakaguchi, Chikara Kokubu, Akira Suzuki, Noriyuki Namba, Norio Sakai, Shigeo Nakajima, Kenji Imai & Keiichi Ozono. (2008) Lrp6 Hypomorphic Mutation Affects Bone Mass Through Bone Resorption in Mice and Impairs Interaction With Mesd. Journal of Bone and Mineral Research 23:10, pages 1661-1671.
Crossref
Mark R Haussler, Carol A Haussler, Leonid Bartik, G Kerr Whitfield, Jui-Cheng Hsieh, Stephanie Slater & Peter W Jurutka. (2008) Vitamin D receptor: molecular signaling and actions of nutritional ligands in disease prevention. Nutrition Reviews 66, pages S98-S112.
Crossref
John H. White. (2008) Vitamin D Signaling, Infectious Diseases, and Regulation of Innate Immunity. Infection and Immunity 76:9, pages 3837-3843.
Crossref
Mayumi Saeki, Kouichi Kurose, Masahiro Tohkin & Ryuichi Hasegawa. (2008) Identification of the functional vitamin D response elements in the human MDR1 gene. Biochemical Pharmacology 76:4, pages 531-542.
Crossref
Lee A. Zella, Nirupama K. Shevde, Bruce W. Hollis, Nancy E. Cooke & J. Wesley Pike. (2008) Vitamin D-Binding Protein Influences Total Circulating Levels of 1,25-Dihydroxyvitamin D3 but Does Not Directly Modulate the Bioactive Levels of the Hormone in Vivo. Endocrinology 149:7, pages 3656-3667.
Crossref
A. Liesegang, K. Singer & A. Boos. (2008) Vitamin D receptor amounts across different segments of the gastrointestinal tract in Brown Swiss and Holstein Frisean cows of different age. Journal of Animal Physiology and Animal Nutrition 92:3, pages 316-323.
Crossref
Robert D. Nerenz, Melissa L. Martowicz & J. Wesley Pike. (2008) An Enhancer 20 Kilobases Upstream of the Human Receptor Activator of Nuclear Factor-κB Ligand Gene Mediates Dominant Activation by 1,25-Dihydroxyvitamin D3. Molecular Endocrinology 22:5, pages 1044-1056.
Crossref
Kumaran Sundaram, Santhosh K. Mani, Kazuyuki Kitatani, Kongming Wu, Richard G. Pestell & Sakamuri V. Reddy. (2008) DACH1 negatively regulates the human RANK ligand gene expression in stromal/preosteoblast cells. Journal of Cellular Biochemistry 103:6, pages 1747-1759.
Crossref
Katharina Riner, Alois Boos, Michael Hässig & Annette Liesegang. (2008) Vitamin D receptor distribution in intestines of domesticated sheepOvis ammon f. aries. Journal of Morphology 269:2, pages 144-152.
Crossref
Carlo Galli, Lee A. Zella, Jackie A. Fretz, Qiang Fu, J. Wesley Pike, Robert S. Weinstein, Stavros C. Manolagas & Charles A. O’Brien. (2008) Targeted Deletion of a Distant Transcriptional Enhancer of the Receptor Activator of Nuclear Factor-κB Ligand Gene Reduces Bone Remodeling and Increases Bone Mass. Endocrinology 149:1, pages 146-153.
Crossref
Peter W Jurutka, Leonid Bartik, G Kerr Whitfield, Douglas R Mathern, Thomas K Barthel, Miriam Gurevich, Jui-Cheng Hsieh, Magdalena Kaczmarska, Carol A Haussler & Mark R Haussler. (2007) Vitamin D Receptor: Key Roles in Bone Mineral Pathophysiology, Molecular Mechanism of Action, and Novel Nutritional Ligands. Journal of Bone and Mineral Research 22:S2, pages V2-V10.
Crossref
J Wesley Pike, Lee A Zella, Mark B Meyer, Jackie A Fretz & Sungtae Kim. (2007) Molecular Actions of 1,25-Dihydroxyvitamin D3 on Genes Involved in Calcium Homeostasis. Journal of Bone and Mineral Research 22:S2, pages V16-V19.
Crossref
. (2007) Current World Literature. Current Opinion in Endocrinology, Diabetes & Obesity 14:6, pages 494-503.
Crossref
Weihua Yuan, Wei Pan, Juan Kong, Wei Zheng, Frances L. Szeto, Kari E. Wong, Ronald Cohen, Anna Klopot, Zhongyi Zhang & Yan Chun Li. (2007) 1,25-Dihydroxyvitamin D3 Suppresses Renin Gene Transcription by Blocking the Activity of the Cyclic AMP Response Element in the Renin Gene Promoter. Journal of Biological Chemistry 282:41, pages 29821-29830.
Crossref
Daniel D Bikle. (2007) What is new in vitamin D: 2006–2007. Current Opinion in Rheumatology 19:4, pages 383-388.
Crossref
J. Wesley Pike, Mark B. Meyer, Makoto Watanuki, Sungtae Kim, Lee A. Zella, Jackie A. Fretz, Miwa Yamazaki & Nirupama K. Shevde. (2007) Perspectives on mechanisms of gene regulation by 1,25-dihydroxyvitamin D3 and its receptor. The Journal of Steroid Biochemistry and Molecular Biology 103:3-5, pages 389-395.
Crossref

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