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Molecular and Cellular Biology Volume 35, 2015 - Issue 14
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Article

Disruption of Wnt/β-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells

Ozlem Kulaka Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
,
Hua Chenb Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas, USA;d Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, Texas, USA
,
Brody Holohana Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
,
Xiaofeng Wua Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
,
Huawei Heb Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas, USA;d Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, Texas, USA
,
Dominika Borekc Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, USA;d Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, Texas, USA
,
Zbyszek Otwinowskic Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, USA;d Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, Texas, USA
,
Kiyoshi Yamaguchie Division of Clinical Genome Research, Advanced Clinical Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan
,
Lauren A. Garofaloc Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, USA
,
Zhiqiang Mac Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, USA
,
Woodring Wrighta Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
,
Chuo Chenc Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, USA
,
Jerry W. Shaya Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
,
Xuewu Zhangb Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas, USA;d Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, Texas, USACorrespondence[email protected] [email protected]
&
Lawrence Luma Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USACorrespondence[email protected] [email protected]
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Pages 2425-2435 | Received 15 Apr 2015, Accepted 28 Apr 2015, Published online: 20 Mar 2023

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Chirag C. Mehta & Hardik G. Bhatt. (2021) Tankyrase inhibitors as antitumor agents: a patent update (2013 – 2020). Expert Opinion on Therapeutic Patents 31:7, pages 645-661.
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Lakshmanan Loganathan, Karthikeyan Muthusamy, John Marshal Jayaraj, Afrinrilwana Kajamaideen & Josephine Julia Balthasar. (2019) In silico insights on tankyrase protein: A potential target for colorectal cancer. Journal of Biomolecular Structure and Dynamics 37:14, pages 3637-3648.
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