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Molecular and Cellular Biology Volume 33, 2013 - Issue 21
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Article

Multipoint Binding of the SLP-76 SH2 Domain to ADAP Is Critical for Oligomerization of SLP-76 Signaling Complexes in Stimulated T Cells

Nathan P. Coussensa Laboratory of Cellular and Molecular Biology, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA
,
Ryo Hayashib Laboratory of Cell Biology, National Cancer Institute, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA
,
Patrick H. Brownc Biomedical Engineering and Physical Sciences Shared Resource, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA
,
Lakshmi Balagopalana Laboratory of Cellular and Molecular Biology, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA
,
Andrea Balboc Biomedical Engineering and Physical Sciences Shared Resource, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA
,
Itoro Akpana Laboratory of Cellular and Molecular Biology, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA
,
Jon C. D. Houtmana Laboratory of Cellular and Molecular Biology, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA
,
Valarie A. Barra Laboratory of Cellular and Molecular Biology, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA
,
Peter Schuckd Dynamics of Macromolecular Assembly Section, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA
,
Ettore Appellab Laboratory of Cell Biology, National Cancer Institute, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA
&
Lawrence E. Samelsona Laboratory of Cellular and Molecular Biology, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USACorrespondence[email protected]
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Pages 4140-4151 | Received 03 Apr 2013, Accepted 08 Aug 2013, Published online: 20 Mar 2023

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Martin G. Sauer, Jessica Herbst, Ulf Diekmann, Christopher E. Rudd & Christian Kardinal. (2016) SHP-1 Acts as a Key Regulator of Alloresponses by Modulating LFA-1-Mediated Adhesion in Primary Murine T Cells. Molecular and Cellular Biology 36:24, pages 3113-3127.
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Benno Kuropka, Burkhart Schraven, Stefanie Kliche, Eberhard Krause & Christian Freund. (2016) Tyrosine-phosphorylation of the scaffold protein ADAP and its role in T cell signaling. Expert Review of Proteomics 13:6, pages 545-554.
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Junya Wada, Udumbara Rathnayake, Lisa M. Jenkins, Avinash Singh, Moosa Mohammadi, Ettore Appella, Paul A. Randazzo & Lawrence E. Samelson. (2022) In vitro reconstitution reveals cooperative mechanisms of adapter protein-mediated activation of phospholipase C-γ1 in T cells. Journal of Biological Chemistry 298:3, pages 101680.
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