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Article

Chaperone Hsp27, a Novel Subunit of AUF1 Protein Complexes, Functions in AU-Rich Element-Mediated mRNA Decay

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Pages 5223-5237 | Received 15 Mar 2008, Accepted 11 Jun 2008, Published online: 27 Mar 2023

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Ales Cvekl & Carolina Eliscovich. (2021) Crystallin gene expression: Insights from studies of transcriptional bursting. Experimental Eye Research 207, pages 108564.
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So Mee Kwon, Seongki Min, Un‐woo Jeoun, Min Seok Sim, Gu Hyun Jung, Sun Mi Hong, Byul A. Jee, Hyun Goo Woo, Changhan Lee & Gyesoon Yoon. (2020) Global spliceosome activity regulates entry into cellular senescence. The FASEB Journal 35:1.
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Carrie E Barnum, Salma Al Saai, Shaili D Patel, Catherine Cheng, Deepti Anand, Xiaolu Xu, Soma Dash, Archana D Siddam, Lisa Glazewski, Emily Paglione, Shawn W Polson, Shinichiro Chuma, Robert W Mason, Shuo Wei, Mona Batish, Velia M Fowler & Salil A Lachke. (2020) The Tudor-domain protein TDRD7, mutated in congenital cataract, controls the heat shock protein HSPB1 (HSP27) and lens fiber cell morphology. Human Molecular Genetics 29:12, pages 2076-2097.
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Yutaro Uchida, Tomoki Chiba, Ryota Kurimoto & Hiroshi Asahara. (2019) Post-transcriptional regulation of inflammation by RNA-binding proteins via cis-elements of mRNAs. The Journal of Biochemistry 166:5, pages 375-382.
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Hiroshi Otsuka, Akira Fukao, Yoshinori Funakami, Kent E. Duncan & Toshinobu Fujiwara. (2019) Emerging Evidence of Translational Control by AU-Rich Element-Binding Proteins. Frontiers in Genetics 10.
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Wendy Ullmer & Bert L. Semler. (2018) Direct and Indirect Effects on Viral Translation and RNA Replication Are Required for AUF1 Restriction of Enterovirus Infections in Human Cells. mBio 9:5.
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Muskan Gupta & Gurcharan Kaur. (2018) Withania somnifera as a Potential Anxiolytic and Anti-inflammatory Candidate Against Systemic Lipopolysaccharide-Induced Neuroinflammation. NeuroMolecular Medicine 20:3, pages 343-362.
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Elise R. Breed, Carolyn A. Hilliard, Benyam Yoseph, Rohit Mittal, Zhe Liang, Ching-Wen Chen, Eileen M. Burd, Luke P. Brewster, Laura M. Hansen, Rudolph L. GleasonJr.Jr., Tej K. Pandita, Mandy L. Ford, Clayton R. Hunt & Craig M. Coopersmith. (2018) The small heat shock protein HSPB1 protects mice from sepsis. Scientific Reports 8:1.
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Guopei Zheng, Zhijie Zhang, Hao Liu, Yan Xiong, Liyun Luo, Xiaoting Jia, Cong Peng, Qiong Zhang, Nan Li, Yixue Gu, Minying Lu, Ying Song, Hao Pan, Jinbao Liu, Wanqing Liu & Zhimin He. (2018) HSP27-Mediated Extracellular and Intracellular Signaling Pathways Synergistically Confer Chemoresistance in Squamous Cell Carcinoma of Tongue. Clinical Cancer Research 24:5, pages 1163-1175.
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Jennifer Defren & Gary Brewer. 2018. Encyclopedia of Signaling Molecules. Encyclopedia of Signaling Molecules 2403 2407 .
Julia Wattacheril, Kristie L. Rose, Salisha Hill, Christian Lanciault, Clark R. Murray, Kay Washington, Brandon Williams, Wayne English, Matthew Spann, Ronald Clements, Naji Abumrad & Charles Robb Flynn. (2017) Non-alcoholic fatty liver disease phosphoproteomics: A functional piece of the precision puzzle. Hepatology Research 47:13, pages 1469-1483.
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Patrick L. Heilman, SungWon Song, Carlos J. Miranda, Kathrin Meyer, Amit K. Srivastava, Amy Knapp, Christopher G. Wier, Brian K. Kaspar & Stephen J. Kolb. (2017) HSPB1 mutations causing hereditary neuropathy in humans disrupt non-cell autonomous protection of motor neurons. Experimental Neurology 297, pages 101-109.
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Stephane Esnault, Zhong-Jian Shen & James S. Malter. (2017) Protein Translation and Signaling in Human Eosinophils. Frontiers in Medicine 4.
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Elizabeth J.F. White, Aerielle E. Matsangos & Gerald M. Wilson. (2017) AUF1 regulation of coding and noncoding RNA. Wiley Interdisciplinary Reviews: RNA 8:2, pages e1393.
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Pavel Kovarik, Florian Ebner & Vitaly Sedlyarov. (2017) Posttranscriptional regulation of cytokine expression. Cytokine 89, pages 21-26.
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Eva Hadadi, Biyan Zhang, Kajus Baidžajevas, Nurhashikin Yusof, Kia Joo Puan, Siew Min Ong, Wei Hseun Yeap, Olaf Rotzschke, Endre Kiss-Toth, Heather Wilson & Siew Cheng Wong. (2016) Differential IL-1β secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability. Scientific Reports 6:1.
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Jiahui Chen, Lihui Liu, Guifeng Wei, Wei Wu, Huaxia Luo, Jiao Yuan, Jianjun Luo & Runsheng Chen. (2016) The long noncoding RNA ASNR regulates degradation of Bcl-2 mRNA through its interaction with AUF1. Scientific Reports 6:1.
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Emanuela Corsini, Valentina Galbiati, Angela Papale, Elena Kummer, Antonella Pinto, Antonio Guaita & Marco Racchi. (2016) The role of HSP27 in RACK1-mediated PKC activation in THP-1 cells. Immunologic Research 64:4, pages 940-950.
Crossref
Jing-Yi Lin, Gary Brewer & Mei-Ling Li. (2015) HuR and Ago2 Bind the Internal Ribosome Entry Site of Enterovirus 71 and Promote Virus Translation and Replication. PLOS ONE 10:10, pages e0140291.
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Takashi Toyama, Yumi Abiko, Yuko Katayama, Toshiyuki Kaji & Yoshito Kumagai. (2015) <i>S</i>-Mercuration of ubiquitin carboxyl-terminal hydrolase L1 through Cys152 by methylmercury causes inhibition of its catalytic activity and reduction of monoubiquitin levels in SH-SY5Y cells. The Journal of Toxicological Sciences 40:6, pages 887-893.
Crossref
André-Patrick Arrigo, Benjamin Ducarouge, Fabrice Lavial & Benjamin Gibert. 2015. The Big Book on Small Heat Shock Proteins. The Big Book on Small Heat Shock Proteins 27 83 .
David Dávila, Eva M. Jiménez-Mateos, Claire M. Mooney, Guillermo Velasco, David C. Henshall & Jochen H. M. Prehn. (2014) Hsp27 binding to the 3′UTR of bim mRNA prevents neuronal death during oxidative stress–induced injury: a novel cytoprotective mechanism . Molecular Biology of the Cell 25:21, pages 3413-3423.
Crossref
Jing-Yi Lin, Mei-Ling Li & Gary Brewer. (2014) mRNA Decay Factor AUF1 Binds the Internal Ribosomal Entry Site of Enterovirus 71 and Inhibits Virus Replication. PLoS ONE 9:7, pages e103827.
Crossref
Ashleigh E. Moore, Devon M. Chenette, Lauren C. Larkin & Robert J. Schneider. (2014) Physiological networks and disease functions of RNA-binding protein AUF1. Wiley Interdisciplinary Reviews: RNA 5:4, pages 549-564.
Crossref
André-Patrick Arrigo & Benjamin Gibert. (2014) HspB1, HspB5 and HspB4 in Human Cancers: Potent Oncogenic Role of Some of Their Client Proteins. Cancers 6:1, pages 333-365.
Crossref
Xiankui Sun, Zhigang Zhou, David J. Fink & Marina Mata. (2013) HspB1 silences translation of PDZ-RhoGEF by enhancing miR-20a and miR-128 expression to promote neurite extension. Molecular and Cellular Neuroscience 57, pages 111-119.
Crossref
Christopher D. Krause, Gina Digioia, Lara S. Izotova, Junxia Xie, Youngsun Kim, Barbara J. Schwartz, Olga V. Mirochnitchenko & Sidney Pestka. (2013) Ligand-independent interaction of the type I interferon receptor complex is necessary to observe its biological activity. Cytokine 64:1, pages 286-297.
Crossref
Christopher D. Krause, Gina Digioia, Lara S. Izotova & Sidney Pestka. (2013) Improving the spectral analysis of fluorescence resonance energy transfer in live cells: Application to interferon receptors and Janus kinases. Cytokine 64:1, pages 272-285.
Crossref
Christopher D. Krause, Lara S. Izotova & Sidney Pestka. (2013) Analytical use of multi-protein fluorescence resonance energy transfer to demonstrate membrane-facilitated interactions within cytokine receptor complexes. Cytokine 64:1, pages 298-309.
Crossref
Beth E. Zucconi & Gerald M. Wilson. (2013) Assembly of Functional Ribonucleoprotein Complexes by AU-rich Element RNA-binding Protein 1 (AUF1) Requires Base-dependent and -independent RNA Contacts. Journal of Biological Chemistry 288:39, pages 28034-28048.
Crossref
André-Patrick Arrigo. (2013) Human small heat shock proteins: Protein interactomes of homo- and hetero-oligomeric complexes: An update. FEBS Letters 587:13, pages 1959-1969.
Crossref
Takuya Uehata & Shizuo Akira. (2013) mRNA degradation by the endoribonuclease Regnase-1/ZC3H12a/MCPIP-1. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1829:6-7, pages 708-713.
Crossref
Elizabeth J.F. White, Gary Brewer & Gerald M. Wilson. (2013) Post-transcriptional control of gene expression by AUF1: Mechanisms, physiological targets, and regulation. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1829:6-7, pages 680-688.
Crossref
Ugo Moens, Sergiy Kostenko & Baldur Sveinbjørnsson. (2013) The Role of Mitogen-Activated Protein Kinase-Activated Protein Kinases (MAPKAPKs) in Inflammation. Genes 4:2, pages 101-133.
Crossref
Xiangyue Wu, Sandra Chesoni, Gaelle Rondeau, Christi Tempesta, Reshma Patel, Sandy Charles, Naznin Daginawala, Beth E. Zucconi, Aparna Kishor, Guangwu Xu, Yufang Shi, Mei-Ling Li, Patricia Irizarry-Barreto, John Welsh, Gerald M. Wilson & Gary Brewer. (2013) Combinatorial mRNA binding by AUF1 and Argonaute 2 controls decay of selected target mRNAs. Nucleic Acids Research 41:4, pages 2644-2658.
Crossref
Christian Kroun Damgaard & Jens Lykke-Andersen. 2013. RNA and Cancer. RNA and Cancer 153 180 .
Xiangyue Wu & Gary Brewer. (2012) The regulation of mRNA stability in mammalian cells: 2.0. Gene 500:1, pages 10-21.
Crossref
Hong Xin, Julie A. Brown, Changning Gong, Hao Fan, Gary Brewer & James R. Gnarra. (2012) Association of the von Hippel–Lindau Protein with AUF1 and Posttranscriptional Regulation of VEGFA mRNA. Molecular Cancer Research 10:1, pages 108-120.
Crossref
Øyvind L. Busk, Caroline Frizzell, Steven Verhaegen, Silvio Uhlig, Lisa Connolly, Erik Ropstad & Morten Sørlie. (2012) Cytosol protein regulation in H295R steroidogenesis model induced by the zearalenone metabolites, α- and β-zearalenol. Toxicon 59:1, pages 17-24.
Crossref
Ruma Pengal, Adam J. Guess, Shipra Agrawal, Joshua Manley, Richard F. Ransom, Robert J. Mourey, Rainer Benndorf & William E. Smoyer. (2011) Inhibition of the protein kinase MK-2 protects podocytes from nephrotic syndrome-related injury. American Journal of Physiology-Renal Physiology 301:3, pages F509-F519.
Crossref
Christopher D Krause, Lara S Izotova, Gwangwen Ren, Zeng-Rong Yuan, Yufang Shi, Chiann-Chyi Chen, Yacov Ron & Sidney Pestka. (2011) Efficient co-expression of bicistronic proteins in mesenchymal stem cells by development and optimization of a multifunctional plasmid. Stem Cell Research & Therapy 2:2.
Crossref
Salil A. LachkeFowzan S. AlkurayaStephen C. KneelandTakbum OhnAnton AboukhalilGareth R. HowellIrfan SaadiResy CavallescoYingzi YueAnne C-H. TsaiK. Saidas NairMihai I. CosmaRichard S. SmithEmily HodgesSuad M. AlFadhliAmal Al-HajeriHanan E. ShamseldinAbdulMutalib BehbehaniGregory J. HannonMartha L. BulykArlene V. DrackPaul J. AndersonSimon W. M. JohnRichard L. Maas. (2011) Mutations in the RNA Granule Component TDRD7 Cause Cataract and Glaucoma. Science 331:6024, pages 1571-1576.
Crossref
María Gabriela Thomas, Mariela Loschi, María Andrea Desbats & Graciela Lidia Boccaccio. (2011) RNA granules: The good, the bad and the ugly. Cellular Signalling 23:2, pages 324-334.
Crossref
Sreevidya Sivaswamy, Edward J. Neafsey & Michael A. Collins. (2010) Neuroprotective preconditioning of rat brain cultures with ethanol: potential transduction by PKC isoforms and focal adhesion kinase upstream of increases in effector heat shock proteins. European Journal of Neuroscience 32:11, pages 1800-1812.
Crossref
Frances M. Gratacós & Gary Brewer. (2010) The role of AUF1 in regulated mRNA decay. Wiley Interdisciplinary Reviews: RNA 1:3, pages 457-473.
Crossref
Xiankui Sun, Jean-Marc Fontaine, Adam D. Hoppe, Serena Carra, Cheryl DeGuzman, Jody L. Martin, Stephanie Simon, Patrick Vicart, Michael J. Welsh, Jacques Landry & Rainer Benndorf. (2010) Abnormal interaction of motor neuropathy-associated mutant HspB8 (Hsp22) forms with the RNA helicase Ddx20 (gemin3). Cell Stress and Chaperones 15:5, pages 567-582.
Crossref
Aurelie de ThonelJulie VandekerckhoveDavid LanneauSubramaniam SelvakumarGeneviève CourtoisAdonis HazoumeMathilde BrunetSebastien MaurelArlette HammannJean Antoine RibeilYael ZermatiAnne Sophie GabetJoan BoyesEric Solary, Olivier Hermine & Carmen Garrido. (2010) HSP27 controls GATA-1 protein level during erythroid cell differentiation. Blood 116:1, pages 85-96.
Crossref
Christina Papadopoulou, Meropi Patrinou-Georgoula & Apostolia Guialis. (2010) Extensive association of HuR with hnRNP proteins within immunoselected hnRNP and mRNP complexes. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1804:4, pages 692-703.
Crossref
Stephen J. Kolb, Scott Sutton & Daniel R. Schoenberg. (2010) RNA processing defects associated with diseases of the motor neuron. Muscle & Nerve 41:1, pages 5-17.
Crossref
Leandro C Cerchietti, Eloisi C Lopes, Shao Ning Yang, Katerina Hatzi, Karen L Bunting, Lucas A Tsikitas, Alka Mallik, Ana I Robles, Jennifer Walling, Lyuba Varticovski, Rita Shaknovich, Kapil N Bhalla, Gabriela Chiosis & Ari Melnick. (2009) A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6–dependent B cell lymphomas. Nature Medicine 15:12, pages 1369-1376.
Crossref
Sergiy Kostenko & Ugo Moens. (2009) Heat shock protein 27 phosphorylation: kinases, phosphatases, functions and pathology. Cellular and Molecular Life Sciences 66:20, pages 3289-3307.
Crossref
Shomita S. Mathew, Megan P. Della Selva & April D. Burch. (2009) Modification and Reorganization of the Cytoprotective Cellular Chaperone Hsp27 during Herpes Simplex Virus Type 1 Infection. Journal of Virology 83:18, pages 9304-9312.
Crossref

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